Obstacles and Recommendations for Clinical Translation of Nanoparticle System-Based Targeted Alpha-Particle Therapy

Nanotechnology for Modern Medicine: Next Steps Towards Clinical Translation

(2021) Shrey Sindhwani et al.   JOURNAL OF INTERNAL MEDICINE

Clinical Perspectives of Theranostics

(2021) Shozo Okamoto et al.   MOLECULES

Emerging Radionuclides in a Regulatory Framework for Medicinal Products – How Do They Fit?

(2021) Clemens Decristoforo et al.   Frontiers in Medicine

Realizing Clinical Trials with Astatine-211: The Chemistry Infrastructure

(2020) Sture Lindegren et al.   CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

Nanohydroxyapatite and its textures as potential carriers of promising short-lived lead isotopes

(2020) A. V. Severin et al.   RUSSIAN CHEMICAL BULLETIN

A Proof-of-Concept Study on the Therapeutic Potential of Au Nanoparticles Radiolabeled with the Alpha-Emitter Actinium-225

(2020) Evangelia-Alexandra Salvanou et al.   Pharmaceutics

Smart Nanotheranostics Responsive to Pathological Stimuli

(2020) Alessandro Parodi et al.   Frontiers in Bioengineering and Biotechnology

Targeted Alpha Therapy: Current Clinical Applications

(2020) Francisco D.C. Guerra Liberal et al.   CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

Development of Ga-68 radiolabeled DOTA functionalized and acetylated PAMAM dendrimer-coated iron oxide nanoparticles as PET/MR dual-modal imaging agent

(2020) Tinoosh Almasi et al.   International Journal of Polymeric Materials and Polymeric Biomaterials

Sub‐10 nm Radiolabeled Barium Sulfate Nanoparticles as Carriers for Theranostic Applications and Targeted Alpha Therapy

(2020) Falco Reissig et al.   ChemistryOpen

Nanoparticles in Targeted Alpha Therapy

(2020) Agnieszka Majkowska-Pilip et al.   Nanomaterials

Atomic Nanogenerators in Targeted Alpha Therapies: Curie’s Legacy in Modern Cancer Management

(2020) Mareike Roscher et al.   Pharmaceuticals

Trastuzumab Modified Barium Ferrite Magnetic Nanoparticles Labeled with Radium-223: A New Potential Radiobioconjugate for Alpha Radioimmunotherapy

(2020) Weronika Gawęda et al.   Nanomaterials

Activity and Adverse Events of Actinium-225-PSMA-617 in Advanced Metastatic Castration-resistant Prostate Cancer After Failure of Lutetium-177-PSMA

(2020) Benedikt Feuerecker et al.   EUROPEAN UROLOGY

Trastuzumab-Modified Gold Nanoparticles Labeled with 211At as a Prospective Tool for Local Treatment of HER2-Positive Breast Cancer

(2019) Łucja Dziawer et al.   Nanomaterials

Gadolinium vanadate nanocrystals as carriers of α-emitters (225Ac, 227Th) and contrast agents

(2019) Miguel Toro-González et al.   JOURNAL OF APPLIED PHYSICS

Targeted alpha therapy with bismuth-213 and actinium-225: Meeting future demand

(2019) F. Bruchertseifer et al.   JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

Radiolabeling nanomaterials for multimodality imaging: New insights into nuclear medicine and cancer diagnosis

(2019) Jianxian Ge et al.   BIOMATERIALS

Recent advances on thermosensitive and pH-sensitive liposomes employed in controlled release

(2019) Marjan Abri Aghdam et al.   JOURNAL OF CONTROLLED RELEASE

Neuroendocrine Tumor Therapy: 177Lu-DOTATATE

(2018) Erik S. Mittra   AMERICAN JOURNAL OF ROENTGENOLOGY

Prolonged survival in secondary glioblastoma following local injection of targeted alpha therapy with 213Bi-substance P analogue

(2018) Leszek Krolicki et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Progress in Targeted Alpha-Particle Therapy. What We Learned about Recoils Release from In Vivo Generators

(2018) Ján Kozempel et al.   MOLECULES

Alpha-Emitters and Targeted Alpha Therapy in Oncology: from Basic Science to Clinical Investigations

(2018) Mehran Makvandi et al.   Targeted Oncology

Current Trends and Challenges in the Clinical Translation of Nanoparticulate Nanomedicines: Pathways for Translational Development and Commercialization

(2018) Susan Hua et al.   Frontiers in Pharmacology

Radiopharmaceutical enhancement by drug delivery systems: A review

(2018) Janke Kleynhans et al.   JOURNAL OF CONTROLLED RELEASE

A Status Report on FDA Approval of Medical Devices Containing Nanostructured Materials

(2018) A-Andrew D. Jones et al.   TRENDS IN BIOTECHNOLOGY

Health Concerns of Various Nanoparticles: A Review of Their in Vitro and in Vivo Toxicity

(2018) Marziyeh Ajdary et al.   Nanomaterials

Nanomedicine: Principles, Properties, and Regulatory Issues

(2018) Sara Soares et al.   Frontiers in Chemistry

Nanoparticles for Biomedical Imaging: Fundamentals of Clinical Translation

(2018) Hak Soo Choi et al.   Molecular Imaging

An overview of nanoscale radionuclides and radiolabeled nanomaterials commonly used for nuclear molecular imaging and therapeutic functions

(2018) Leila Farzin et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Targeted Alpha Therapy, an Emerging Class of Cancer Agents

(2018) et al.   JAMA Oncology

Theranostic and nanotheranostic probes in nuclear medicine

(2017) Natascha Drude et al.   METHODS

Alpha Particle Enhanced Blood Brain/Tumor Barrier Permeabilization in Glioblastomas Using Integrin Alpha-v Beta-3–Targeted Liposomes

(2017) Anirudh Sattiraju et al.   MOLECULAR CANCER THERAPEUTICS

Nanozeolite bioconjugates labeled with 223 Ra for targeted alpha therapy

(2017) Agata Piotrowska et al.   NUCLEAR MEDICINE AND BIOLOGY

Gold nanoparticle bioconjugates labelled with 211At for targeted alpha therapy

(2017) L. Dziawer et al.   RSC Advances

The Clinical Translation of Organic Nanomaterials for Cancer Therapy: A Focus on Polymeric Nanoparticles, Micelles, Liposomes and Exosomes

(2017) Stefano Palazzolo et al.   CURRENT MEDICINAL CHEMISTRY

Study of 223Ra uptake mechanism by Fe3O4 nanoparticles: towards new prospective theranostic SPIONs

(2016) Olga Mokhodoeva et al.   JOURNAL OF NANOPARTICLE RESEARCH

225Ac-PSMA-617 for PSMA-Targeted  -Radiation Therapy of Metastatic Castration-Resistant Prostate Cancer

(2016) C. Kratochwil et al.   JOURNAL OF NUCLEAR MEDICINE

Regulatory aspects on nanomedicines

(2015) Vanessa Sainz et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Branched amphiphilic peptide capsules: Cellular uptake and retention of encapsulated solutes

(2014) Pinakin Sukthankar et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Theranostic Nanoparticles

(2014) F. Chen et al.   JOURNAL OF NUCLEAR MEDICINE

Physicochemical Properties of Nanomaterials: Implication in Associated Toxic Manifestations

(2014) Manzoor Ahmad Gatoo et al.   Biomed Research International

Retention studies of recoiling daughter nuclides of 225Ac in polymer vesicles

(2013) G. Wang et al.   APPLIED RADIATION AND ISOTOPES

PSA-responsive and PSMA-mediated multifunctional liposomes for targeted therapy of prostate cancer

(2013) Bai Xiang et al.   BIOMATERIALS

Nanotoxicological classification system (NCS) – A guide for the risk-benefit assessment of nanoparticulate drug delivery systems

(2013) Cornelia M. Keck et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Functionalized NaA nanozeolites labeled with 224,225Ra for targeted alpha therapy

(2013) Agata Piotrowska et al.   JOURNAL OF NANOPARTICLE RESEARCH

Anti-Prostate-Specific Membrane Antigen Liposomes Loaded with 225Ac for Potential Targeted Antivascular  -Particle Therapy of Cancer

(2013) A. Bandekar et al.   JOURNAL OF NUCLEAR MEDICINE

Production of [211At]-Astatinated Radiopharmaceuticals and Applications in Targeted α-Particle Therapy

(2012) François Guérard et al.   CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

A review of current nanoparticle and targeting moieties for the delivery of cancer therapeutics

(2012) Stephanie D. Steichen et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Radiolabelling of engineered nanoparticles for in vitro and in vivo tracing applications using cyclotron accelerators

(2011) N. Gibson et al.   ARCHIVES OF TOXICOLOGY

LaPO4Nanoparticles Doped with Actinium-225 that Partially Sequester Daughter Radionuclides

(2011) Jonathan Woodward et al.   BIOCONJUGATE CHEMISTRY

In vivo212Pb/212Bi generator using indium-DTPA-tagged liposomes

(2011) A. Le Du et al.   RADIOCHIMICA ACTA

Drug delivery and nanoparticles: Applications and hazards

(2010) de Jong   International Journal of Nanomedicine

Enhanced Loading Efficiency and Retention of225Ac in Rigid Liposomes for Potential Targeted Therapy of Micrometastases

(2008) Min-Yuan Chang et al.   BIOCONJUGATE CHEMISTRY