A membrane protein display platform for receptor interactome discovery

Dual proteome-scale networks reveal cell-specific remodeling of the human interactome

(2021) Edward L. Huttlin et al.   CELL

Cell-Surface Proteomic Profiling in the Fly Brain Uncovers Wiring Regulators

(2020) Jiefu Li et al.   CELL

Microenvironment mapping via Dexter energy transfer on immune cells

(2020) Jacob B. Geri et al.   SCIENCE

The Immunoglobulin Superfamily Receptome Defines Cancer-Relevant Networks Associated with Clinical Outcome

(2020) Erik Verschueren et al.   CELL

Molecular Characterization of the Coproduced Extracellular Vesicles in HEK293 during Virus-Like Particle Production

(2020) Jesús Lavado-García et al.   JOURNAL OF PROTEOME RESEARCH

PANTHER version 16: a revised family classification, tree-based classification tool, enhancer regions and extensive API

(2020) Huaiyu Mi et al.   NUCLEIC ACIDS RESEARCH

CD248: A therapeutic target in cancer and fibrotic diseases

(2019) Beverly A. Teicher   Oncotarget

An anti-apoptotic HEK293 cell line provides a robust and high titer platform for transient protein expression in bioreactors

(2019) Tia A Arena et al.   mAbs

Development and application of a high-content virion display human GPCR array

(2019) Guan-Da Syu et al.   Nature Communications

A platform for extracellular interactome discovery identifies novel functional binding partners for the immune receptors B7-H3/CD276 and PVR/CD155

(2019) Bushra Husain et al.   MOLECULAR & CELLULAR PROTEOMICS

The generation and use of recombinant extracellular vesicles as biological reference material

(2019) Edward Geeurickx et al.   Nature Communications

Single-cell RNA sequencing reveals stromal evolution into LRRC15+ myofibroblasts as a determinant of patient response to cancer immunotherapy

(2019) Claudia X Dominguez et al.   Cancer Discovery

LRRC15 Is a Novel Mesenchymal Protein and Stromal Target for Antibody–Drug Conjugates

(2018) James W. Purcell et al.   CANCER RESEARCH

Isolation of state-dependent monoclonal antibodies against the 12-transmembrane domain glucose transporter 4 using virus-like particles

(2018) David F. Tucker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapid isolation and enrichment of extracellular vesicle preparations using anion exchange chromatography

(2018) Nikki Heath et al.   Scientific Reports

An Unbiased Screen for Human Cytomegalovirus Identifies Neuropilin-2 as a Central Viral Receptor

(2018) Nadia Martinez-Martin et al.   CELL

ProLIF – quantitative integrin protein–protein interactions and synergistic membrane effects on proteoliposomes

(2018) Nicola De Franceschi et al.   JOURNAL OF CELL SCIENCE

STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

(2018) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

The in silico human surfaceome

(2018) Damaris Bausch-Fluck et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Getting to know the neighborhood: using proximity-dependent biotinylation to characterize protein complexes and map organelles

(2018) Anne-Claude Gingras et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Recent advances in nanodisc technology for membrane protein studies (2012-2017)

(2017) John E. Rouck et al.   FEBS LETTERS

GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses

(2017) Zefang Tang et al.   NUCLEIC ACIDS RESEARCH

A subcellular map of the human proteome

(2017) Peter J. Thul et al.   SCIENCE

Technologies for Proteome-Wide Discovery of Extracellular Host-Pathogen Interactions

(2017) Nadia Martinez-Martin   Journal of Immunology Research

Extracellular vesicles for drug delivery

(2016) Pieter Vader et al.   ADVANCED DRUG DELIVERY REVIEWS

ExoCarta: A Web-Based Compendium of Exosomal Cargo

(2016) Shivakumar Keerthikumar et al.   JOURNAL OF MOLECULAR BIOLOGY

A comprehensive map of molecular drug targets

(2016) Rita Santos et al.   NATURE REVIEWS DRUG DISCOVERY

Magneto-nanosensor platform for probing low-affinity protein–protein interactions and identification of a low-affinity PD-L1/PD-L2 interaction

(2016) Jung-Rok Lee et al.   Nature Communications

Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles

(2014) Marina Colombo et al.   Annual Review of Cell and Developmental Biology

The basic structure and dynamics of cell membranes: An update of the Singer–Nicolson model

(2014) Félix M. Goñi   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Quantitative analysis of mammalian GIRK2 channel regulation by G proteins, the signaling lipid PIP2 and Na+ in a reconstituted system

(2014) Weiwei Wang et al.   eLife

VirD: A Virion Display Array for Profiling Functional Membrane Proteins

(2013) Shaohui Hu et al.   ANALYTICAL CHEMISTRY

Generation of HIV-1 Gag VLPs by transient transfection of HEK 293 suspension cell cultures using an optimized animal-derived component free medium

(2013) Laura Cervera et al.   JOURNAL OF BIOTECHNOLOGY

Ligand-based receptor identification on living cells and tissues using TRICEPS

(2013) Andreas P Frei et al.   Nature Protocols

Binding constants of membrane-anchored receptors and ligands depend strongly on the nanoscale roughness of membranes

(2013) J. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fc-fusion proteins: new developments and future perspectives

(2012) Daniel M. Czajkowsky et al.   EMBO Molecular Medicine

CD248 facilitates tumor growth via its cytoplasmic domain

(2011) Margarida Maia et al.   BMC CANCER

High-throughput identification of transient extracellular protein interactions

(2010) Gavin J. Wright et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Signal initiation in biological systems: the properties and detection of transient extracellular protein interactions

(2009) Gavin J. Wright   Molecular BioSystems

Virus-like Particles as Quantitative Probes of Membrane Protein Interactions†

(2008) Sharon Willis et al.   BIOCHEMISTRY

Endosialin Protein Expression and Therapeutic Target Potential in Human Solid Tumors: Sarcoma versus Carcinoma

(2008) C. Rouleau et al.   CLINICAL CANCER RESEARCH

Large-scale screening for novel low-affinity extracellular protein interactions

(2008) K. M. Bushell et al.   GENOME RESEARCH

Exosome Function: From Tumor Immunology to Pathogen Biology

(2008) Jeffrey S. Schorey et al.   TRAFFIC