Development and application of a high-content virion display human GPCR array

Pharmacogenomics of GPCR Drug Targets

(2018) Alexander S. Hauser et al.   CELL

G Protein-Coupled Receptors as Targets for Approved Drugs: How Many Targets and How Many Drugs?

(2018) Krishna Sriram et al.   MOLECULAR PHARMACOLOGY

2017 FDA drug approvals

(2018) Asher Mullard   NATURE REVIEWS DRUG DISCOVERY

Measuring Ligand Binding Kinetics to Membrane Proteins Using Virion Nano-oscillators

(2018) Guangzhong Ma et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

2016 FDA drug approvals

(2017) Asher Mullard   NATURE REVIEWS DRUG DISCOVERY

Trends in GPCR drug discovery: new agents, targets and indications

(2017) Alexander S. Hauser et al.   NATURE REVIEWS DRUG DISCOVERY

A Controlled Trial of Erenumab for Episodic Migraine

(2017) Peter J. Goadsby et al.   NEW ENGLAND JOURNAL OF MEDICINE

Kinetic and high-throughput profiling of epigenetic interactions by 3D-carbene chip-based surface plasmon resonance imaging technology

(2017) Shuai Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cysteinyl leukotrienes as novel host factors facilitatingCryptococcus neoformanspenetration into the brain

(2016) Longkun Zhu et al.   CELLULAR MICROBIOLOGY

Plain Silver Surface Plasmon Resonance for Microarray Application

(2015) Zhiqiang Cheng et al.   ANALYTICAL CHEMISTRY

Real-Time Monitoring of Phosphorylation Kinetics with Self-Assembled Nano-oscillators

(2015) Yimin Fang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Antibody anarchy: A call to order

(2015) Monya Baker   NATURE

Reproducibility: Standardize antibodies used in research

(2015) Andrew Bradbury et al.   NATURE

Editorial: Antibody Can Get It Right: Confronting Problems of Antibody Specificity and Irreproducibility

(2014) Agnes Schonbrunn   MOLECULAR ENDOCRINOLOGY

Generating thermostabilized agonist-bound GPR40/FFAR1 using virus-like particles and a label-free binding assay

(2014) Yoshihiko Hirozane et al.   MOLECULAR MEMBRANE BIOLOGY

Detection of Charges and Molecules with Self-Assembled Nano-Oscillators

(2014) Xiaonan Shan et al.   NANO LETTERS

Montelukast, a Cysteinyl Leukotriene Receptor-1 Antagonist Protects Against Hippocampal Injury Induced by Transient Global Cerebral Ischemia and Reperfusion in Rats

(2014) M. A. Saad et al.   NEUROCHEMICAL RESEARCH

Cysteinyl leukotriene receptor (CysLT) antagonists decrease pentylenetetrazol-induced seizures and blood–brain barrier dysfunction

(2014) Q.F. Lenz et al.   NEUROSCIENCE

Exposure of human astrocytes to leukotriene C4 promotes a CX3CL1/fractalkine-mediated transmigration of HIV-1-infected CD4+ T cells across an in vitro blood–brain barrier model

(2014) Jonathan Bertin et al.   VIROLOGY

VirD: A Virion Display Array for Profiling Functional Membrane Proteins

(2013) Shaohui Hu et al.   ANALYTICAL CHEMISTRY

Reconstitution of Membrane Proteins into Model Membranes: Seeking Better Ways to Retain Protein Activities

(2013) Hsin-Hui Shen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Lack of Specificity of Commercial Antibodies Leads to Misidentification of Angiotensin Type 1 Receptor Protein

(2012) Marcela Herrera et al.   HYPERTENSION

Rapid Identification of Monospecific Monoclonal Antibodies Using a Human Proteome Microarray

(2012) Jun Seop Jeong et al.   MOLECULAR & CELLULAR PROTEOMICS

Host Cytosolic Phospholipase A2α Contributes to Group B Streptococcus Penetration of the Blood-Brain Barrier

(2011) Ravi Maruvada et al.   INFECTION AND IMMUNITY

Herpes simplex virus infects most cell types in vitro: clues to its success

(2011) Ghadah A Karasneh et al.   Virology Journal

Mammalian cell transfection: the present and the future

(2010) Tae Kyung Kim et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Antibody validation

(2010) Jennifer Bordeaux et al.   BIOTECHNIQUES

Comparative transfection of DNA into primary and transformed mammalian cells from different lineages

(2010) Rosalie Maurisse et al.   BMC BIOTECHNOLOGY

Meningococcus Hijacks a β2-Adrenoceptor/β-Arrestin Pathway to Cross Brain Microvasculature Endothelium

(2010) Mathieu Coureuil et al.   CELL

The nanodisc: a novel tool for membrane protein studies

(2009) Jonas Borch et al.   BIOLOGICAL CHEMISTRY

Atypical Responsiveness of the Orphan Receptor GPR55 to Cannabinoid Ligands

(2009) Ankur Kapur et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

How and why do GPCRs dimerize?

(2008) Vsevolod V. Gurevich et al.   TRENDS IN PHARMACOLOGICAL SCIENCES