Quantitative analysis of mammalian GIRK2 channel regulation by G proteins, the signaling lipid PIP2 and Na+ in a reconstituted system

Serotonin induces depolarization in lateral amygdala neurons by activation of TRPC-like current and inhibition of GIRK current depending on 5-HT2C receptor

(2014) Ryo Yamamoto et al.   NEUROPHARMACOLOGY

X-ray structure of the mammalian GIRK2–βγ G-protein complex

(2013) Matthew R. Whorton et al.   NATURE

Phosphoinositides: Tiny Lipids With Giant Impact on Cell Regulation

(2013) Tamas Balla   PHYSIOLOGICAL REVIEWS

Conformational Changes Underlying Pore Dilation in the Cytoplasmic Domain of Mammalian Inward Rectifier K+ Channels

(2013) Atsushi Inanobe et al.   PLoS One

Structural Basis for Modulation of Gating Property of G Protein-gated Inwardly Rectifying Potassium Ion Channel (GIRK) by i/o-family G Protein α Subunit (Gαi/o)

(2012) Yoko Mase et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structure of the Human K2P TRAAK, a Lipid- and Mechano-Sensitive K+ Ion Channel

(2012) S. G. Brohawn et al.   SCIENCE

Crystal Structure of the Mammalian GIRK2 K+ Channel and Gating Regulation by G Proteins, PIP2, and Sodium

(2011) Matthew R. Whorton et al.   CELL

Two Distinct Aspects of Coupling between GαiProtein and G Protein-activated K+Channel (GIRK) Revealed by Fluorescently Labeled Gαi3Protein Subunits

(2011) Shai Berlin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Agonist-induced Localization of Gq-coupled Receptors and G Protein-gated Inwardly Rectifying K+(GIRK) Channels to Caveolae Determines Receptor Specificity of Phosphatidylinositol 4,5-Bisphosphate Signaling

(2010) Shanyu Cui et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Structural Determinant for the Control of PIP2Sensitivity in G Protein-gated Inward Rectifier K+Channels

(2010) Atsushi Inanobe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NMR Analyses of the Gβγ Binding and Conformational Rearrangements of the Cytoplasmic Pore of G Protein-activated Inwardly Rectifying Potassium Channel 1 (GIRK1)

(2010) Mariko Yokogawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Emerging roles for G protein-gated inwardly rectifying potassium (GIRK) channels in health and disease

(2010) Christian Lüscher et al.   NATURE REVIEWS NEUROSCIENCE

Gαiand Gβγ Jointly Regulate the Conformations of a Gβγ Effector, the Neuronal G Protein-activated K+Channel (GIRK)

(2009) Shai Berlin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Divergent regulation of GIRK1 and GIRK2 subunits of the neuronal G protein gated K+channel by GαiGDPand Gβγ

(2009) Moran Rubinstein et al.   JOURNAL OF PHYSIOLOGY-LONDON

Emerging role(s) of G-protein α-subunits in the gating of GIRKs

(2009) Wolfgang Schreibmayer   JOURNAL OF PHYSIOLOGY-LONDON

New sites of action for GIRK and SK channels

(2009) Rafael Luján et al.   NATURE REVIEWS NEUROSCIENCE

Functional Analysis of Kv1.2 and Paddle Chimera Kv Channels in Planar Lipid Bilayers

(2008) Xiao Tao et al.   JOURNAL OF MOLECULAR BIOLOGY

Membrane recognition by phospholipid-binding domains

(2008) Mark A. Lemmon   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Membrane lipids: where they are and how they behave

(2008) Gerrit van Meer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY