CD248 facilitates tumor growth via its cytoplasmic domain

Development of a Fully Human Anti-PDGFRβ Antibody That Suppresses Growth of Human Tumor Xenografts and Enhances Antitumor Activity of an Anti-VEGFR2 Antibody

(2015) Juqun Shen et al.   NEOPLASIA

Colorectal Cancer Cells Activate Adjacent Fibroblasts Resulting in FGF1/FGFR3 Signaling and Increased Invasion

(2011) Maria L. Henriksson et al.   AMERICAN JOURNAL OF PATHOLOGY

Pten in the Breast Tumor Microenvironment: Modeling Tumor–Stroma Coevolution: Figure 1.

(2011) Julie A. Wallace et al.   CANCER RESEARCH

CD248 and its cytoplasmic domain: A therapeutic target for arthritis

(2010) Margarida Maia et al.   ARTHRITIS AND RHEUMATISM

Matricellular proteins: from homeostasis to inflammation, cancer, and metastasis

(2010) Claudia Chiodoni et al.   CANCER AND METASTASIS REVIEWS

Endosialin/TEM-1/CD248 regulates pericyte proliferation through PDGF receptor signaling

(2010) Brian Tomkowicz et al.   CANCER BIOLOGY & THERAPY

The pericyte and stromal cell marker CD248 (endosialin) is required for efficient lymph node expansion

(2010) Siân Lax et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Hallmarks of cancer: Interactions with the tumor stroma

(2010) Kristian Pietras et al.   EXPERIMENTAL CELL RESEARCH

Notch and Transforming Growth Factor-β (TGFβ) Signaling Pathways Cooperatively Regulate Vascular Smooth Muscle Cell Differentiation

(2010) Yuefeng Tang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of placenta growth factor and its receptor flt-1 in rheumatoid inflammation: A link between angiogenesis and inflammation

(2009) Seung-Ah Yoo et al.   ARTHRITIS AND RHEUMATISM

Malignant cells fuel tumor growth by educating infiltrating leukocytes to produce the mitogen Gas6

(2009) S. Loges et al.   BLOOD

Characterization of TEM1/endosialinin human and murine brain tumors

(2009) Eleanor B Carson-Walter et al.   BMC CANCER

NOTCH3 Expression Is Induced in Mural Cells Through an Autoregulatory Loop That Requires Endothelial-Expressed JAGGED1

(2009) Hua Liu et al.   CIRCULATION RESEARCH

Cancer-associated fibroblasts and tumor growth – bystanders turning into key players

(2009) Arne Östman et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Cancer associated fibroblasts (CAFs) in tumor microenvironment

(2009) Fei Xing   Frontiers in Bioscience-Landmark

Human mesenchymal stem cells from bone marrow express tumor endothelial and stromal markers

(2009) Bagley   INTERNATIONAL JOURNAL OF ONCOLOGY

Responsiveness of Stromal Fibroblasts to IFN-  Blocks Tumor Growth via Angiostasis

(2009) Y. Lu et al.   JOURNAL OF IMMUNOLOGY

Proinflammatory Role of Vascular Endothelial Growth Factor in the Pathogenesis of Rheumatoid Arthritis: Prospects for Therapeutic Intervention

(2009) Seung-Ah Yoo et al.   MEDIATORS OF INFLAMMATION

HEY1 Leu94Met gene polymorphism dramatically modifies its biological functions

(2009) M A Villaronga et al.   ONCOGENE

Mesenchymal Stem Cell Transition to Tumor-Associated Fibroblasts Contributes to Fibrovascular Network Expansion and Tumor Progression

(2009) Erika L. Spaeth et al.   PLoS One

Limited Role of Murine ATM in Oncogene-Induced Senescence and p53-Dependent Tumor Suppression

(2009) Alejo Efeyan et al.   PLoS One

Cancer associated fibroblasts in cancer pathogenesis

(2009) Omar E. Franco et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Hijacking HES1: how tumors co-opt the anti-differentiation strategies of quiescent cells

(2009) Liyun Sang et al.   TRENDS IN MOLECULAR MEDICINE

Endosialin (Tem1) Is a Marker of Tumor-Associated Myofibroblasts and Tumor Vessel-Associated Mural Cells

(2008) Sven Christian et al.   AMERICAN JOURNAL OF PATHOLOGY

TGFBI Deficiency Predisposes Mice to Spontaneous Tumor Development

(2008) Y. Zhang et al.   CANCER RESEARCH

Endosialin Protein Expression and Therapeutic Target Potential in Human Solid Tumors: Sarcoma versus Carcinoma

(2008) C. Rouleau et al.   CLINICAL CANCER RESEARCH

Tumor stroma marker endosialin (Tem1) is a binding partner of metastasis-related protein Mac-2 BP/90K

(2008) Renate Becker et al.   FASEB JOURNAL

Molecular aspects of rheumatoid arthritis: role of transcription factors

(2008) Hiroshi Okamoto et al.   FEBS Journal

Role of platelet-derived growth factors in physiology and medicine

(2008) J. Andrae et al.   GENES & DEVELOPMENT

Transgelin: An actin-binding protein and tumour suppressor

(2008) Stephen J. Assinder et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Endosialin/TEM 1/CD248 is a pericyte marker of embryonic and tumor neovascularization

(2008) Rebecca G. Bagley et al.   MICROVASCULAR RESEARCH

Endosialin (CD248) is a marker of tumor-associated pericytes in high-grade glioma

(2008) Nicole Simonavicius et al.   MODERN PATHOLOGY

Notch tumor suppressor function

(2008) G P Dotto   ONCOGENE

Notch signaling regulates tumor angiogenesis by diverse mechanisms

(2008) J Dufraine et al.   ONCOGENE

Functions of Paracrine PDGF Signaling in the Proangiogenic Tumor Stroma Revealed by Pharmacological Targeting

(2008) Kristian Pietras et al.   PLOS MEDICINE