Functional and Biochemical Consequences of Disease Variants in Neurotransmitter Transporters: A Special Emphasis on Folding and Trafficking Deficits
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Title
Functional and Biochemical Consequences of Disease Variants in Neurotransmitter Transporters: A Special Emphasis on Folding and Trafficking Deficits
Authors
Keywords
Neurotransmitter, Transporter, SLC6, Disease variants, Folding, Pharmacochaperoning
Journal
PHARMACOLOGY & THERAPEUTICS
Volume 222, Issue -, Pages 107785
Publisher
Elsevier BV
Online
2020-12-11
DOI
10.1016/j.pharmthera.2020.107785
References
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- Sialin (SLC17A5) functions as a nitrate transporter in the plasma membrane
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- Identification of congenital muscular dystonia 2 associated with an inherited GlyT2 defect in Belgian Blue cattle from the United Kingdom
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- The Neuronal Transporter Gene SLC6A15 Confers Risk to Major Depression
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- New advances in NMDA receptor pharmacology
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- Orphan Transporter SLC6A18 Is Renal Neutral Amino Acid Transporter B0AT3
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- Choline transporter gene variation is associated with attention-deficit hyperactivity disorder
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- The Vesicular Acetylcholine Transporter Is Required for Neuromuscular Development and Function
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- Association of SLC6A4 variants with obsessive-compulsive disorder in a large multicenter US family study
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- Enhanced tonic GABAA inhibition in typical absence epilepsy
- (2009) David W Cope et al. NATURE MEDICINE
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- Novel and functional norepinephrine transporter protein variants identified in attention-deficit hyperactivity disorder
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- Impairment of SLC17A8 Encoding Vesicular Glutamate Transporter-3, VGLUT3, Underlies Nonsyndromic Deafness DFNA25 and Inner Hair Cell Dysfunction in Null Mice
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- Function of taurine transporter (Slc6a6/TauT) as a GABA transporting protein and its relevance to GABA transport in rat retinal capillary endothelial cells
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- Tissue-Specific Amino Acid Transporter Partners ACE2 and Collectrin Differentially Interact With Hartnup Mutations
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- Multivariate permutation analysis associates multiple polymorphisms with subphenotypes of major depression
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- The Substrates of the γ-Aminobutyric Acid Transporter GAT-1 Induce Structural Rearrangements around the Interface of Transmembrane Domains 1 and 6
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- Molecular physiology and pathophysiology of lysosomal membrane transporters
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- Peptide-Based Interactions with Calnexin Target Misassembled Membrane Proteins into Endoplasmic Reticulum-Derived Multilamellar Bodies
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- Cellular distribution of the neutral amino acid transporter subtype ASCT2 in mouse brain
- (2008) Catherine M. Gliddon et al. JOURNAL OF NEUROCHEMISTRY
- Synaptic Homeostasis in a Zebrafish Glial Glycine Transporter Mutant
- (2008) Rebecca Mongeon et al. JOURNAL OF NEUROPHYSIOLOGY
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- Vesicular Glutamate Transporter 3 Is Required for Synaptic Transmission in Zebrafish Hair Cells
- (2008) N. Obholzer et al. JOURNAL OF NEUROSCIENCE
- Anomalous Dopamine Release Associated with a Human Dopamine Transporter Coding Variant
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- The Orphan Transporter Rxt1/NTT4 (SLC6A17) Functions as a Synaptic Vesicle Amino Acid Transporter Selective for Proline, Glycine, Leucine, and Alanine
- (2008) L. A. Parra et al. MOLECULAR PHARMACOLOGY
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