De novo mutation in the dopamine transporter gene associates dopamine dysfunction with autism spectrum disorder

A C-terminal PDZ domain-binding sequence is required for striatal distribution of the dopamine transporter

(2013) Mattias Rickhag et al.   Nature Communications

Crystal Structure of an Activated Variant of Small Heat Shock Protein Hsp16.5

(2012) Hassane S. Mchaourab et al.   BIOCHEMISTRY

Genetic architecture in autism spectrum disorder

(2012) Bernie Devlin et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Reward circuitry dysfunction in psychiatric and neurodevelopmental disorders and genetic syndromes: animal models and clinical findings

(2012) Gabriel S Dichter et al.   Journal of Neurodevelopmental Disorders

The membrane raft protein Flotillin-1 is essential in dopamine neurons for amphetamine-induced behavior in Drosophila

(2012) A B Pizzo et al.   MOLECULAR PSYCHIATRY

X-ray structures of LeuT in substrate-free outward-open and apo inward-open states

(2012) Harini Krishnamurthy et al.   NATURE

Patterns and rates of exonic de novo mutations in autism spectrum disorders

(2012) Benjamin M. Neale et al.   NATURE

De novo mutations revealed by whole-exome sequencing are strongly associated with autism

(2012) Stephan J. Sanders et al.   NATURE

An integrated map of genetic variation from 1,092 human genomes

(2012)   NATURE

Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations

(2012) Brian J. O’Roak et al.   NATURE

De Novo Gene Disruptions in Children on the Autistic Spectrum

(2012) Ivan Iossifov et al.   NEURON

A Modular Toolset for Recombination Transgenesis and Neurogenetic Analysis of Drosophila

(2012) Ji-Wu Wang et al.   PLoS One

MAOA, DBH, and SLC6A4 variants in CHARGE: a case-control study of autism spectrum disorders

(2011) Flora Tassone et al.   Autism Research

Substrate-modulated gating dynamics in a Na+-coupled neurotransmitter transporter homologue

(2011) Yongfang Zhao et al.   NATURE

Rare De Novo and Transmitted Copy-Number Variation in Autistic Spectrum Disorders

(2011) Dan Levy et al.   NEURON

Multiple Recurrent De Novo CNVs, Including Duplications of the 7q11.23 Williams Syndrome Region, Are Strongly Associated with Autism

(2011) Stephan J. Sanders et al.   NEURON

Effects of Fluoxetine Treatment on Striatal Dopamine Transporter Binding and Cerebrospinal Fluid Insulin-Like Growth Factor-1 in Children with Autism

(2011) I. Makkonen et al.   NEUROPEDIATRICS

Psychopathological aspects of dopaminergic gene polymorphisms in adolescence and young adulthood

(2011) Zsofia Nemoda et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

SLC6 Neurotransmitter Transporters: Structure, Function, and Regulation

(2011) A. S. Kristensen et al.   PHARMACOLOGICAL REVIEWS

The Substrate-Driven Transition to an Inward-Facing Conformation in the Functional Mechanism of the Dopamine Transporter

(2011) Jufang Shan et al.   PLoS One

Toward the Fourth Dimension of Membrane Protein Structure: Insight into Dynamics from Spin-Labeling EPR Spectroscopy

(2011) Hassane S. Mchaourab et al.   STRUCTURE

Brain Serotonin and Dopamine Transporter Bindings in Adults With High-Functioning Autism

(2010) Kazuhiko Nakamura et al.   ARCHIVES OF GENERAL PSYCHIATRY

Increased Sensitivity and Extended Range of Distance Measurements in Spin-Labeled Membrane Proteins: Q-Band Double Electron-Electron Resonance and Nanoscale Bilayers

(2010) Ping Zou et al.   BIOPHYSICAL JOURNAL

Association of DRD4 polymorphism with severity of oppositional defiant disorder, separation anxiety disorder and repetitive behaviors in children with autism spectrum disorder

(2010) Kenneth D. Gadow et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Dysregulation of Dopamine Transporters via Dopamine D2 Autoreceptors Triggers Anomalous Dopamine Efflux Associated with Attention-Deficit Hyperactivity Disorder

(2010) E. Bowton et al.   JOURNAL OF NEUROSCIENCE

Clinical and molecular characterisation of hereditary dopamine transporter deficiency syndrome: an observational cohort and experimental study

(2010) Manju A Kurian et al.   LANCET NEUROLOGY

Functional impact of global rare copy number variation in autism spectrum disorders

(2010) Dalila Pinto et al.   NATURE

Ion/substrate-dependent conformational dynamics of a bacterial homolog of neurotransmitter:sodium symporters

(2010) Derek P Claxton et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The binding sites for benztropines and dopamine in the dopamine transporter overlap

(2010) Heidi Bisgaard et al.   NEUROPHARMACOLOGY

Dysregulation of the Norepinephrine Transporter Sustains Cortical Hypodopaminergia and Schizophrenia-Like Behaviors in Neuronal Rictor Null Mice

(2010) Michael A. Siuta et al.   PLOS BIOLOGY

Examination of association to autism of common genetic variationin genes related to dopamine

(2009) B.M. Anderson et al.   Autism Research

The role of dopamine in bipolar disorder

(2009) David A Cousins et al.   BIPOLAR DISORDERS

A single nucleotide polymorphism in the human serotonin transporter introduces a new site for N-linked glycosylation

(2009) Trine N. Rasmussen et al.   NEUROPHARMACOLOGY

A DRD1 haplotype is associated with risk for autism spectrum disorders in male‐only affected sib‐pair families

(2008) Joe A. Hettinger et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Dopamine Signaling in the Dorsal Striatum Is Essential for Motivated Behaviors

(2008) Richard D. Palmiter   Annals of the New York Academy of Sciences

A Common Variant in DRD3 Receptor Is Associated with Autism Spectrum Disorder

(2008) Mariken de Krom et al.   BIOLOGICAL PSYCHIATRY

Association of ADHD, tics, and anxiety with dopamine transporter (DAT1) genotype in autism spectrum disorder

(2008) Kenneth D. Gadow et al.   JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY

Evidence for overlapping genetic influences on autistic and ADHD behaviours in a community twin sample

(2008) Angelica Ronald et al.   JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY

Interaction of dopamine, female pheromones, locomotion and sex behavior in Drosophila melanogaster

(2008) Claude Wicker-Thomas et al.   JOURNAL OF INSECT PHYSIOLOGY

Anomalous Dopamine Release Associated with a Human Dopamine Transporter Coding Variant

(2008) M. S. Mazei-Robison et al.   JOURNAL OF NEUROSCIENCE

A Juxtamembrane Mutation in the N Terminus of the Dopamine Transporter Induces Preference for an Inward-Facing Conformation

(2008) B. Guptaroy et al.   MOLECULAR PHARMACOLOGY

Copy-number variations associated with neuropsychiatric conditions

(2008) Edwin H. Cook Jr et al.   NATURE

The binding sites for cocaine and dopamine in the dopamine transporter overlap

(2008) Thijs Beuming et al.   NATURE NEUROSCIENCE