SLC6A3 coding variant Ala559Val found in two autism probands alters dopamine transporter function and trafficking

Decoding the contribution of dopaminergic genes and pathways to autism spectrum disorder (ASD)

(2014) Michael Nguyen et al.   NEUROCHEMISTRY INTERNATIONAL

Protein kinase Cβ is a modulator of the dopamine D2 autoreceptor-activated trafficking of the dopamine transporter

(2013) Rong Chen et al.   JOURNAL OF NEUROCHEMISTRY

De novo mutation in the dopamine transporter gene associates dopamine dysfunction with autism spectrum disorder

(2013) P J Hamilton et al.   MOLECULAR PSYCHIATRY

X-ray structure of dopamine transporter elucidates antidepressant mechanism

(2013) Aravind Penmatsa et al.   NATURE

Social reward requires coordinated activity of nucleus accumbens oxytocin and serotonin

(2013) Gül Dölen et al.   NATURE

Rare Complete Knockouts in Humans: Population Distribution and Significant Role in Autism Spectrum Disorders

(2013) Elaine T. Lim et al.   NEURON

Underconnectivity between voice-selective cortex and reward circuitry in children with autism

(2013) D. A. Abrams et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pharmacological treatments prescribed to people with autism spectrum disorder (ASD) in primary health care

(2013) Macey L. Murray et al.   PSYCHOPHARMACOLOGY

Analysis of Rare, Exonic Variation amongst Subjects with Autism Spectrum Disorders and Population Controls

(2013) Li Liu et al.   PLoS Genetics

Genetic architecture in autism spectrum disorder

(2012) Bernie Devlin et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

The dopamine transporter haplotype and reward-related striatal responses in adult ADHD

(2012) Martine Hoogman et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Psychostimulants for ADHD-like symptoms in individuals with autism spectrum disorders

(2012) Samuele Cortese et al.   Expert Review of Neurotherapeutics

Dopamine transporter polymorphisms affect social approach-avoidance tendencies

(2012) D. Enter et al.   GENES BRAIN AND BEHAVIOR

Rescue of Dopamine Transporter Function in Hypoinsulinemic Rats by a D2 Receptor-ERK-Dependent Mechanism

(2012) W. A. Owens et al.   JOURNAL OF NEUROSCIENCE

Attention Deficit/Hyperactivity Disorder-Derived Coding Variation in the Dopamine Transporter Disrupts Microdomain Targeting and Trafficking Regulation

(2012) D. Sakrikar et al.   JOURNAL OF NEUROSCIENCE

Patterns and rates of exonic de novo mutations in autism spectrum disorders

(2012) Benjamin M. Neale et al.   NATURE

De novo mutations revealed by whole-exome sequencing are strongly associated with autism

(2012) Stephan J. Sanders et al.   NATURE

Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations

(2012) Brian J. O’Roak et al.   NATURE

De Novo Gene Disruptions in Children on the Autistic Spectrum

(2012) Ivan Iossifov et al.   NEURON

Clinical Practice Pathways for Evaluation and Medication Choice for Attention-Deficit/Hyperactivity Disorder Symptoms in Autism Spectrum Disorders

(2012) Rajneesh Mahajan et al.   PEDIATRICS

Altered Serotonin, Dopamine and Norepinepherine Levels in 15q Duplication and Angelman Syndrome Mouse Models

(2012) M. Febin Farook et al.   PLoS One

Effect of Dopamine Transporter Genotype on Intrinsic Functional Connectivity Depends on Cognitive State

(2011) Evan M. Gordon et al.   CEREBRAL CORTEX

Flotillin-1 is essential for PKC-triggered endocytosis and membrane microdomain localization of DAT

(2011) M Laura Cremona et al.   NATURE NEUROSCIENCE

Rare De Novo and Transmitted Copy-Number Variation in Autistic Spectrum Disorders

(2011) Dan Levy et al.   NEURON

Multiple Recurrent De Novo CNVs, Including Duplications of the 7q11.23 Williams Syndrome Region, Are Strongly Associated with Autism

(2011) Stephan J. Sanders et al.   NEURON

Effects of Fluoxetine Treatment on Striatal Dopamine Transporter Binding and Cerebrospinal Fluid Insulin-Like Growth Factor-1 in Children with Autism

(2011) I. Makkonen et al.   NEUROPEDIATRICS

SLC6 Neurotransmitter Transporters: Structure, Function, and Regulation

(2011) A. S. Kristensen et al.   PHARMACOLOGICAL REVIEWS

Akt-Dependent and Isoform-Specific Regulation of Dopamine Transporter Cell Surface Expression

(2010) Nicole K. Speed et al.   ACS Chemical Neuroscience

Brain Serotonin and Dopamine Transporter Bindings in Adults With High-Functioning Autism

(2010) Kazuhiko Nakamura et al.   ARCHIVES OF GENERAL PSYCHIATRY

Association of DRD4 polymorphism with severity of oppositional defiant disorder, separation anxiety disorder and repetitive behaviors in children with autism spectrum disorder

(2010) Kenneth D. Gadow et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Dysregulation of Dopamine Transporters via Dopamine D2 Autoreceptors Triggers Anomalous Dopamine Efflux Associated with Attention-Deficit Hyperactivity Disorder

(2010) E. Bowton et al.   JOURNAL OF NEUROSCIENCE

Functional impact of global rare copy number variation in autism spectrum disorders

(2010) Dalila Pinto et al.   NATURE

Protein kinase C: poised to signal

(2009) Alexandra C. Newton   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Examination of association to autism of common genetic variationin genes related to dopamine

(2009) B.M. Anderson et al.   Autism Research

Comparative Study of Children With ADHD Only, Autism Spectrum Disorder + ADHD, and Chronic Multiple Tic Disorder + ADHD

(2009) Kenneth D. Gadow et al.   Journal of Attention Disorders

A Closer Look at Amphetamine-Induced Reverse Transport and Trafficking of the Dopamine and Norepinephrine Transporters

(2009) S. D. Robertson et al.   MOLECULAR NEUROBIOLOGY

Structural Variation of Chromosomes in Autism Spectrum Disorder

(2008) Christian R. Marshall et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A DRD1 haplotype is associated with risk for autism spectrum disorders in male‐only affected sib‐pair families

(2008) Joe A. Hettinger et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Dopamine Signaling in the Dorsal Striatum Is Essential for Motivated Behaviors

(2008) Richard D. Palmiter   Annals of the New York Academy of Sciences

PI3K signaling supports amphetamine-induced dopamine efflux

(2008) Brandon J. Lute et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A Common Variant in DRD3 Receptor Is Associated with Autism Spectrum Disorder

(2008) Mariken de Krom et al.   BIOLOGICAL PSYCHIATRY

Association of ADHD, tics, and anxiety with dopamine transporter (DAT1) genotype in autism spectrum disorder

(2008) Kenneth D. Gadow et al.   JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY

Currents in Response to Rapid Concentration Jumps of Amphetamine Uncover Novel Aspects of Human Dopamine Transporter Function

(2008) K. Erreger et al.   JOURNAL OF NEUROSCIENCE

Anomalous Dopamine Release Associated with a Human Dopamine Transporter Coding Variant

(2008) M. S. Mazei-Robison et al.   JOURNAL OF NEUROSCIENCE

Involvement of the PRKCB1 gene in autistic disorder: significant genetic association and reduced neocortical gene expression

(2008) C Lintas et al.   MOLECULAR PSYCHIATRY

Copy-number variations associated with neuropsychiatric conditions

(2008) Edwin H. Cook Jr et al.   NATURE

Association between Microdeletion and Microduplication at 16p11.2 and Autism

(2008) Lauren A. Weiss et al.   NEW ENGLAND JOURNAL OF MEDICINE

Structural Basis of Protein Kinase C Isoform Function

(2008) Susan F. Steinberg   PHYSIOLOGICAL REVIEWS

Variation in dopamine genes influences responsivity of the human reward system

(2008) J.-C. Dreher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Amphetamine-induced decreases in dopamine transporter surface expression are protein kinase C-independent

(2007) Ekaterina Boudanova et al.   NEUROPHARMACOLOGY