Conformational state interactions provide clues to the pharmacochaperone potential of serotonin transporter partial substrates

Electrogenic Binding of Intracellular Cations Defines a Kinetic Decision Point in the Transport Cycle of the Human Serotonin Transporter

(2016) Peter S. Hasenhuetl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pharmacological Chaperones of the Dopamine Transporter Rescue Dopamine Transporter Deficiency Syndrome Mutations in Heterologous Cells

(2016) Pieter Beerepoot et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional Rescue of a MisfoldedDrosophila melanogasterDopamine Transporter Mutant Associated with a Sleepless Phenotype by Pharmacological Chaperones

(2016) Ameya Kasture et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The conservative view: is it necessary to implant a stent into the dopamine transporter?

(2015) D Schmid et al.   BRITISH JOURNAL OF PHARMACOLOGY

Potassium fluxes across the endoplasmic reticulum and their role in endoplasmic reticulum calcium homeostasis

(2015) Malle Kuum et al.   CELL CALCIUM

A Salt Bridge Linking the First Intracellular Loop with the C Terminus Facilitates the Folding of the Serotonin Transporter

(2015) Florian Koban et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amphetamines, new psychoactive drugs and the monoamine transporter cycle

(2015) Harald H. Sitte et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Dopamine transporter deficiency syndrome: phenotypic spectrum from infancy to adulthood

(2014) Joanne Ng et al.   BRAIN

A Cytosolic Relay of Heat Shock Proteins HSP70-1A and HSP90β Monitors the Folding Trajectory of the Serotonin Transporter

(2014) Ali El-Kasaby et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A quantitative model of amphetamine action on the 5-HT transporter

(2013) Walter Sandtner et al.   BRITISH JOURNAL OF PHARMACOLOGY

Defining the blanks – Pharmacochaperoning of SLC6 transporters and ABC transporters

(2013) Peter Chiba et al.   PHARMACOLOGICAL RESEARCH

The Mechanistic Basis for Noncompetitive Ibogaine Inhibition of Serotonin and Dopamine Transporters

(2012) Simon Bulling et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Unifying Concept of Serotonin Transporter-associated Currents

(2011) Klaus Schicker et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular chaperones in protein folding and proteostasis

(2011) F. Ulrich Hartl et al.   NATURE

SLC6 Neurotransmitter Transporters: Structure, Function, and Regulation

(2011) A. S. Kristensen et al.   PHARMACOLOGICAL REVIEWS

The Atypical Stimulant and Nootropic Modafinil Interacts with the Dopamine Transporter in a Different Manner than Classical Cocaine-Like Inhibitors

(2011) Kyle C. Schmitt et al.   PLoS One

Mutations in the Carboxyl-terminal SEC24 Binding Motif of the Serotonin Transporter Impair Folding of the Transporter

(2010) Ali El-Kasaby et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The N Terminus of Monoamine Transporters Is a Lever Required for the Action of Amphetamines

(2010) Sonja Sucic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Clinical and molecular characterisation of hereditary dopamine transporter deficiency syndrome: an observational cohort and experimental study

(2010) Manju A Kurian et al.   LANCET NEUROLOGY

Homozygous loss-of-function mutations in the gene encoding the dopamine transporter are associated with infantile parkinsonism-dystonia

(2009) Manju A. Kurian et al.   JOURNAL OF CLINICAL INVESTIGATION

Single Nigrostriatal Dopaminergic Neurons Form Widely Spread and Highly Dense Axonal Arborizations in the Neostriatum

(2009) W. Matsuda et al.   JOURNAL OF NEUROSCIENCE