Novel treatments for autism spectrum disorder based on genomics and systems biology
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Novel treatments for autism spectrum disorder based on genomics and systems biology
Authors
Keywords
Autistic disorder, Drug therapy, Clinical trials
Journal
PHARMACOLOGY & THERAPEUTICS
Volume -, Issue -, Pages 107939
Publisher
Elsevier BV
Online
2021-06-24
DOI
10.1016/j.pharmthera.2021.107939
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Improved symptoms following bumetanide treatment in children aged 3 to 6 years with autism spectrum disorder: a randomized, double-blind, placebo-controlled trial
- (2021) Yuan Dai et al. Science Bulletin
- Simultaneous quantification of GABA, Glx and GSH in the neonatal human brain using magnetic resonance spectroscopy
- (2021) Maria Yanez Lopez et al. NEUROIMAGE
- Modulation of atypical brain activation during executive functioning in autism: a pharmacological MRI study of tianeptine
- (2021) Robert H. Wichers et al. Molecular Autism
- Large-Scale Exome Sequencing Study Implicates Both Developmental and Functional Changes in the Neurobiology of Autism
- (2020) F. Kyle Satterstrom et al. CELL
- The Master Observational Trial: A New Class of Master Protocol to Advance Precision Medicine
- (2020) Dane Dickson et al. CELL
- Autism Spectrum Disorder as a Brain-Gut-Microbiome Axis Disorder
- (2020) Virginia Saurman et al. DIGESTIVE DISEASES AND SCIENCES
- Symptom improvement in children with autism spectrum disorder following bumetanide administration is associated with decreased GABA/glutamate ratios
- (2020) Lingli Zhang et al. Translational Psychiatry
- Autism spectrum disorder
- (2020) Catherine Lord et al. Nature Reviews Disease Primers
- Sulforaphane as an anticancer molecule: mechanisms of action, synergistic effects, enhancement of drug safety, and delivery systems
- (2020) Mohammad M. Kamal et al. ARCHIVES OF PHARMACAL RESEARCH
- Controlled trial of lovastatin combined with an open-label treatment of a parent-implemented language intervention in youth with fragile X syndrome
- (2020) Angela John Thurman et al. Journal of Neurodevelopmental Disorders
- A longitudinal item response model for Aberrant Behavior Checklist (ABC) data from children with autism
- (2020) Elham Haem et al. JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS
- A framework for an evidence-based gene list relevant to autism spectrum disorder
- (2020) Christian P. Schaaf et al. NATURE REVIEWS GENETICS
- Phase II study of oral mTOR inhibitor everolimus for recurrent, radiographic-progressive neurofibromatosis type 1-associated pediatric low-grade glioma A phase II study of continuous oral mTOR inhibitor everolimus for recurrent, radiographic-progressive neurofibromatosis type 1–associated pediatric low-grade glioma: a Neurofibromatosis Clinical Trials Consortium study
- (2020) Nicole J Ullrich et al. NEURO-ONCOLOGY
- Assessing the efficacy and safety of fecal microbiota transplantation and probiotic VSL#3 for active ulcerative colitis: A systematic review and meta-analysis
- (2020) Xiaofei Dang et al. PLoS One
- Inattention and hyperactive/impulsive component scores do not differentiate between autism spectrum disorder and attention-deficit/hyperactivity disorder in a clinical sample
- (2020) Aneta D. Krakowski et al. Molecular Autism
- Bumetanide for Core Symptoms of Autism Spectrum Disorder (BAMBI): A Single Center, Double-Blinded, Participant-Randomized, Placebo-Controlled, Phase Two, Superiority Trial
- (2020) Jan J. Sprengers et al. JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY
- Advances in understanding of Rett syndrome and MECP2 duplication syndrome: prospects for future therapies
- (2020) Alexander J Sandweiss et al. LANCET NEUROLOGY
- Genome-wide detection of tandem DNA repeats that are expanded in autism
- (2020) Brett Trost et al. NATURE
- Regulation of autism-relevant behaviors by cerebellar–prefrontal cortical circuits
- (2020) Elyza Kelly et al. NATURE NEUROSCIENCE
- Immune modulatory treatments for autism spectrum disorder
- (2020) Robyn P. Thom et al. Seminars in Pediatric Neurology
- Measurement of excitation-inhibition ratio in autism spectrum disorder using critical brain dynamics
- (2020) Hilgo Bruining et al. Scientific Reports
- IGF-1 treatment causes unique transcriptional response in neurons from individuals with idiopathic autism
- (2020) Sara B. Linker et al. Molecular Autism
- Effectiveness of N-acetylcysteine in autism spectrum disorders: A meta-analysis of randomized controlled trials
- (2020) Tsung-Min Lee et al. AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY
- Cas9 gene therapy for Angelman syndrome traps Ube3a-ATS long non-coding RNA
- (2020) Justin M. Wolter et al. NATURE
- Drug Development for Cystic Fibrosis
- (2020) Don B. Sanders et al. PEDIATRIC PULMONOLOGY
- Big data approaches to decomposing heterogeneity across the autism spectrum
- (2019) Michael V. Lombardo et al. MOLECULAR PSYCHIATRY
- Pilot study of probiotic/colostrum supplementation on gut function in children with autism and gastrointestinal symptoms
- (2019) Megan R. Sanctuary et al. PLoS One
- Disruption of mTOR and MAPK pathways correlates with severity in idiopathic autism
- (2019) Eleonora Rosina et al. Translational Psychiatry
- Motor cortex excitability and inhibitory imbalance in autism spectrum disorder assessed with transcranial magnetic stimulation: a systematic review
- (2019) Fumi Masuda et al. Translational Psychiatry
- Long-term Risk of Neuropsychiatric Disease After Exposure to Infection In Utero
- (2019) Benjamin J. S. al-Haddad et al. JAMA Psychiatry
- Efficacy and safety of mTOR inhibitors (rapamycin and its analogues) for tuberous sclerosis complex: a meta-analysis
- (2019) Min Li et al. Orphanet Journal of Rare Diseases
- An Exploratory Examination of Neonatal Cytokines and Chemokines as Predictors of Autism Risk: The Early Markers for Autism Study
- (2019) Luke S. Heuer et al. BIOLOGICAL PSYCHIATRY
- Excitation-inhibition balance as a framework for investigating mechanisms in neuropsychiatric disorders
- (2019) Vikaas S. Sohal et al. MOLECULAR PSYCHIATRY
- A phase 2 clinical trial of a vasopressin V1a receptor antagonist shows improved adaptive behaviors in men with autism spectrum disorder
- (2019) Federico Bolognani et al. Science Translational Medicine
- Meta-analysis and multidisciplinary consensus statement: exome sequencing is a first-tier clinical diagnostic test for individuals with neurodevelopmental disorders
- (2019) Siddharth Srivastava et al. GENETICS IN MEDICINE
- Recent advances in molecular therapies for neurological disease: triplet repeat disorders
- (2019) Pedro Gonzalez-Alegre HUMAN MOLECULAR GENETICS
- A randomized controlled trial with everolimus for IQ and autism in tuberous sclerosis complex
- (2019) Iris E. Overwater et al. NEUROLOGY
- The Autism-Associated Gene Scn2a Contributes to Dendritic Excitability and Synaptic Function in the Prefrontal Cortex
- (2019) Perry W.E. Spratt et al. NEURON
- The co-occurrence of epilepsy and autism: A systematic review
- (2019) Sara Lukmanji et al. EPILEPSY & BEHAVIOR
- Serum cytokine levels in children with spectrum autism disorder: Differences in pro- and anti-inflammatory balance
- (2019) Natalia Karolina Kordulewska et al. JOURNAL OF NEUROIMMUNOLOGY
- A meta-analysis of pro-inflammatory cytokines in autism spectrum disorders: Effects of age, gender, and latitude
- (2019) Amene Saghazadeh et al. JOURNAL OF PSYCHIATRIC RESEARCH
- Anti-inflammatory cytokines in autism spectrum disorders: A systematic review and meta-analysis
- (2019) Amene Saghazadeh et al. CYTOKINE
- Mendelian disorders of the epigenetic machinery: postnatal malleability and therapeutic prospects
- (2019) Jill A Fahrner et al. HUMAN MOLECULAR GENETICS
- Heterogeneity and efficacy of antipsychotic treatment for schizophrenia with or without treatment resistance: a meta-analysis
- (2019) Yuya Mizuno et al. NEUROPSYCHOPHARMACOLOGY
- Congenital Heart Disease and Autism: A Case-Control Study
- (2019) Eric R. Sigmon et al. PEDIATRICS
- Examining overlap and homogeneity in ASD, ADHD, and OCD: a data-driven, diagnosis-agnostic approach
- (2019) Azadeh Kushki et al. Translational Psychiatry
- Systematic review and guide to management of core and psychiatric symptoms in youth with autism
- (2018) S. H. Ameis et al. ACTA PSYCHIATRICA SCANDINAVICA
- Epigenetics and autism spectrum disorder: A report of an autism case with mutation in H1 linker histone HIST1H1E and literature review
- (2018) Lara J. Duffney et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS
- Psychiatry in a Dish: Stem Cells and Brain Organoids Modeling Autism Spectrum Disorders
- (2018) Mirolyba Ilieva et al. BIOLOGICAL PSYCHIATRY
- Ketone bodies as epigenetic modifiers
- (2018) Hai-Bin Ruan et al. CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE
- An integrative analysis of non-coding regulatory DNA variations associated with autism spectrum disorder
- (2018) Sarah M. Williams et al. MOLECULAR PSYCHIATRY
- Mechanisms of ketamine action as an antidepressant
- (2018) P Zanos et al. MOLECULAR PSYCHIATRY
- Social deficits in Shank3-deficient mouse models of autism are rescued by histone deacetylase (HDAC) inhibition
- (2018) Luye Qin et al. NATURE NEUROSCIENCE
- Histone deacetylase inhibitor MS-275 restores social and synaptic function in a Shank3-deficient mouse model of autism
- (2018) Kaijie Ma et al. NEUROPSYCHOPHARMACOLOGY
- Histone deacetylases (HDACs) as therapeutic target for depressive disorders
- (2018) Paulina Misztak et al. Pharmacological Reports
- A modified ketogenic gluten-free diet with MCT improves behavior in children with autism spectrum disorder
- (2018) Ryan W.Y. Lee et al. PHYSIOLOGY & BEHAVIOR
- Systematic review and meta-analysis of reported adverse events of long-term intranasal oxytocin treatment for autism spectrum disorder
- (2018) Qizheng Cai et al. PSYCHIATRY AND CLINICAL NEUROSCIENCES
- Folinic Acid Increases Protein Arginine Methylation in Human Endothelial Cells
- (2018) Ruben Esse et al. Nutrients
- Bumetanide for autism: more eye contact, less amygdala activation
- (2018) Nouchine Hadjikhani et al. Scientific Reports
- Randomised controlled trial of simvastatin treatment for autism in young children with neurofibromatosis type 1 (SANTA)
- (2018) Stavros Stivaros et al. Molecular Autism
- Case-control meta-analysis of blood DNA methylation and autism spectrum disorder
- (2018) Shan V. Andrews et al. Molecular Autism
- Placebo-controlled crossover assessment of mecasermin for the treatment of Rett syndrome
- (2018) Heather M. O'Leary et al. Annals of Clinical and Translational Neurology
- Meta-analysis of the diagnostic and clinical utility of genome and exome sequencing and chromosomal microarray in children with suspected genetic diseases
- (2018) Michelle M. Clark et al. npj Genomic Medicine
- Everolimus for epilepsy and autism spectrum disorder in tuberous sclerosis complex: EXIST-3 substudy in Japan
- (2018) Masashi Mizuguchi et al. BRAIN & DEVELOPMENT
- Treatment of Alzheimer's Disease with the GSK-3 Inhibitor Tideglusib: A Pilot Study
- (2018) Teodoro del Ser et al. JOURNAL OF ALZHEIMERS DISEASE
- Development and Validation of Objective and Quantitative Eye Tracking−Based Measures of Autism Risk and Symptom Levels
- (2018) Thomas W. Frazier et al. JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY
- Common genetic variants contribute to risk of rare severe neurodevelopmental disorders
- (2018) Mari E. K. Niemi et al. NATURE
- Progress and potential in organoid research
- (2018) Giuliana Rossi et al. NATURE REVIEWS GENETICS
- Intravenous immunoglobulin for the treatment of autoimmune encephalopathy in children with autism
- (2018) Kathleen Connery et al. Translational Psychiatry
- Autism is a prenatal disorder: Evidence from late gestation brain overgrowth
- (2018) Fréderique Bonnet-Brilhault et al. Autism Research
- Absence of Efficacy of Everolimus in Neurofibromatosis 1-Related Plexiform Neurofibromas: Results from a Phase 2a Trial
- (2018) Ouidad Zehou et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- 5.16 A Phase 2 Randomized, Placebo-Controlled Trial of Tideglusib, an Orally Administered GSK-3 Beta Inhibitor, in the Treatment of Adolescents With ASD
- (2018) Evdokia Anagnostou et al. JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY
- A pilot dose finding study of pioglitazone in autistic children
- (2018) Lucia Capano et al. Molecular Autism
- The contribution of [1H] magnetic resonance spectroscopy to the study of excitation-inhibition in autism
- (2018) Laura A. Ajram et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- The clinical landscape for SMA in a new therapeutic era
- (2017) K Talbot et al. GENE THERAPY
- Histone Deacetylase Inhibitors as Anticancer Drugs
- (2017) Tomas Eckschlager et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Using a Patient-Centered Outcome Measure to Test Methylphenidate Versus Placebo in Children with Autism Spectrum Disorder
- (2017) Lawrence Scahill et al. JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY
- Safety and Efficacy of Memantine in Children with Autism: Randomized, Placebo-Controlled Study and Open-Label Extension
- (2017) Michael G. Aman et al. JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY
- Development and validation of an item response theory-based Social Responsiveness Scale short form
- (2017) Alexandra Sturm et al. JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY
- GRIN2B encephalopathy: novel findings on phenotype, variant clustering, functional consequences and treatment aspects
- (2017) Konrad Platzer et al. JOURNAL OF MEDICAL GENETICS
- Arbaclofen in fragile X syndrome: results of phase 3 trials
- (2017) Elizabeth Berry-Kravis et al. Journal of Neurodevelopmental Disorders
- Insulin-like Growth Factor II Targets the mTOR Pathway to Reverse Autism-like Phenotypes in Mice
- (2017) Adam B. Steinmetz et al. JOURNAL OF NEUROSCIENCE
- Ketogenic diet versus gluten free casein free diet in autistic children: a case-control study
- (2017) Omnia El-Rashidy et al. METABOLIC BRAIN DISEASE
- Prenatal fever and autism risk
- (2017) M Hornig et al. MOLECULAR PSYCHIATRY
- Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders
- (2017) Daniel J Weiner et al. NATURE GENETICS
- Whole genome sequencing resource identifies 18 new candidate genes for autism spectrum disorder
- (2017) Ryan K C Yuen et al. NATURE NEUROSCIENCE
- Drug development for neurodevelopmental disorders: lessons learned from fragile X syndrome
- (2017) Elizabeth M. Berry-Kravis et al. NATURE REVIEWS DRUG DISCOVERY
- Autism genetics: opportunities and challenges for clinical translation
- (2017) Jacob A. S. Vorstman et al. NATURE REVIEWS GENETICS
- SHANK proteins: roles at the synapse and in autism spectrum disorder
- (2017) Patricia Monteiro et al. NATURE REVIEWS NEUROSCIENCE
- R-Baclofen Reverses Cognitive Deficits and Improves Social Interactions in Two Lines of 16p11.2 Deletion Mice
- (2017) Laura J Stoppel et al. NEUROPSYCHOPHARMACOLOGY
- AutDB: a platform to decode the genetic architecture of autism
- (2017) Wayne Pereanu et al. NUCLEIC ACIDS RESEARCH
- Influenza Vaccination in the First Trimester of Pregnancy and Risk of Autism Spectrum Disorder—Reply
- (2017) Ousseny Zerbo et al. JAMA Pediatrics
- Serum and cerebrospinal fluid immune mediators in children with autistic disorder: a longitudinal study
- (2017) Carlos A. Pardo et al. Molecular Autism
- d-Cycloserine enhances durability of social skills training in autism spectrum disorder
- (2017) Logan K. Wink et al. Molecular Autism
- Exaggerated CpH methylation in the autism-affected brain
- (2017) Shannon E. Ellis et al. Molecular Autism
- Environmental risk factors for autism: an evidence-based review of systematic reviews and meta-analyses
- (2017) Amirhossein Modabbernia et al. Molecular Autism
- Shifting brain inhibitory balance and connectivity of the prefrontal cortex of adults with autism spectrum disorder
- (2017) L A Ajram et al. Translational Psychiatry
- Microbiota Transfer Therapy alters gut ecosystem and improves gastrointestinal and autism symptoms: an open-label study
- (2017) Dae-Wook Kang et al. Microbiome
- The Current Status of the Ketogenic Diet in Psychiatry
- (2017) Emmanuelle C. S. Bostock et al. Frontiers in Psychiatry
- Ketogenic diet improves behaviors in a maternal immune activation model of autism spectrum disorder
- (2017) David N. Ruskin et al. PLoS One
- Oxytocin Receptor Polymorphisms are Differentially Associated with Social Abilities across Neurodevelopmental Disorders
- (2017) Danielle A. Baribeau et al. Scientific Reports
- A randomised, double blind, placebo-controlled trial of a fixed dose of N-acetyl cysteine in children with autistic disorder
- (2016) Olivia M Dean et al. AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY
- Oxytocin Treatment, Circuitry, and Autism: A Critical Review of the Literature Placing Oxytocin Into the Autism Context
- (2016) Adam J. Guastella et al. BIOLOGICAL PSYCHIATRY
- Maternal infection during pregnancy and risk of autism spectrum disorders: A systematic review and meta-analysis
- (2016) Hai-yin Jiang et al. BRAIN BEHAVIOR AND IMMUNITY
- Microbial Reconstitution Reverses Maternal Diet-Induced Social and Synaptic Deficits in Offspring
- (2016) Shelly A. Buffington et al. CELL
- Changes in insulin-like growth factor signaling alter phenotypes in Fragile X Mice
- (2016) T. L. Wise GENES BRAIN AND BEHAVIOR
- Derisking Psychiatric Drug Development
- (2016) Margaret C. Grabb et al. JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY
- A Prospective Open-Label Trial of Memantine Hydrochloride for the Treatment of Social Deficits in Intellectually Capable Adults With Autism Spectrum Disorder
- (2016) Gagan Joshi et al. JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY
- Phenotyping, Etiological Factors, and Biomarkers
- (2016) David Q. Beversdorf JOURNAL OF DEVELOPMENTAL AND BEHAVIORAL PEDIATRICS
- A double-blind, placebo-controlled, crossover trial of the selective dopamine D1 receptor antagonist ecopipam in patients with Lesch-Nyhan disease
- (2016) Tanya Khasnavis et al. MOLECULAR GENETICS AND METABOLISM
- Prevention of behavioral deficits in rats exposed to folate receptor antibodies: implication in autism
- (2016) A Desai et al. MOLECULAR PSYCHIATRY
- Autism with intellectual disability is associated with increased levels of maternal cytokines and chemokines during gestation
- (2016) K L Jones et al. MOLECULAR PSYCHIATRY
- Randomized placebo-controlled study of lovastatin in children with neurofibromatosis type 1
- (2016) Jonathan M. Payne et al. NEUROLOGY
- Mice with Shank3 Mutations Associated with ASD and Schizophrenia Display Both Shared and Distinct Defects
- (2016) Yang Zhou et al. NEURON
- Arbaclofen in Children and Adolescents with Autism Spectrum Disorder: A Randomized, Controlled, Phase 2 Trial
- (2016) Jeremy Veenstra-VanderWeele et al. NEUROPSYCHOPHARMACOLOGY
- Maternal immune activation: Implications for neuropsychiatric disorders
- (2016) M. L. Estes et al. SCIENCE
- Memantine Improves Attentional Processes in Fragile X-Associated Tremor/Ataxia Syndrome: Electrophysiological Evidence from a Randomized Controlled Trial
- (2016) Jin-Chen Yang et al. Scientific Reports
- A randomized placebo-controlled pilot study of N-acetylcysteine in youth with autism spectrum disorder
- (2016) Logan K. Wink et al. Molecular Autism
- A randomized, placebo-controlled trial of d-cycloserine for the enhancement of social skills training in autism spectrum disorders
- (2016) Noha F. Minshawi et al. Molecular Autism
- Maternal mid-pregnancy C-reactive protein and risk of autism spectrum disorders: the early markers for autism study
- (2016) O Zerbo et al. Translational Psychiatry
- Practical guidelines for managing adults with 22q11.2 deletion syndrome
- (2015) Wai Lun Alan Fung et al. GENETICS IN MEDICINE
- The Role of Sulforaphane in Epigenetic Mechanisms, Including Interdependence between Histone Modification and DNA Methylation
- (2015) Agnieszka Kaufman-Szymczyk et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Molecular Diagnostic Yield of Chromosomal Microarray Analysis and Whole-Exome Sequencing in Children With Autism Spectrum Disorder
- (2015) Kristiina Tammimies et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- A Pilot Study on the Combination of Applied Behavior Analysis and Bumetanide Treatment for Children with Autism
- (2015) Lin Du et al. JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY
- Whole-genome sequencing of quartet families with autism spectrum disorder
- (2015) Ryan K C Yuen et al. NATURE MEDICINE
- GABAB Receptor Agonist R-Baclofen Reverses Social Deficits and Reduces Repetitive Behavior in Two Mouse Models of Autism
- (2015) J L Silverman et al. NEUROPSYCHOPHARMACOLOGY
- Glycogen synthase kinase-3 (GSK3): Regulation, actions, and diseases
- (2015) Eleonore Beurel et al. PHARMACOLOGY & THERAPEUTICS
- Oxytocin modulates fMRI responses to facial expression in macaques
- (2015) Ning Liu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A randomized, placebo controlled trial of omega-3 fatty acids in the treatment of young children with autism
- (2015) Deepali Mankad et al. Molecular Autism
- Predictors of placebo response in pharmacological and dietary supplement treatment trials in pediatric autism spectrum disorder: a meta-analysis
- (2015) A Masi et al. Translational Psychiatry
- Oxytocin and vasopressin: linking pituitary neuropeptides and their receptors to social neurocircuits
- (2015) Danielle A. Baribeau et al. Frontiers in Neuroscience
- 22q11.2 deletion syndrome
- (2015) Donna M. McDonald-McGinn et al. Nature Reviews Disease Primers
- Convergence of Genes and Cellular Pathways Dysregulated in Autism Spectrum Disorders
- (2014) Dalila Pinto et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Effect of lovastatin on behavior in children and adults with fragile X syndrome: An open-label study
- (2014) Artuela Çaku et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- Psychiatric Disorders From Childhood to Adulthood in 22q11.2 Deletion Syndrome: Results From the International Consortium on Brain and Behavior in 22q11.2 Deletion Syndrome
- (2014) Maude Schneider et al. AMERICAN JOURNAL OF PSYCHIATRY
- Disruptive CHD8 Mutations Define a Subtype of Autism Early in Development
- (2014) Raphael Bernier et al. CELL
- The left inferior frontal gyrus is crucial for reading the mind in the eyes: Brain lesion evidence
- (2014) Olga Dal Monte et al. CORTEX
- Intranasal Ketamine Treatment in an Adult With Autism Spectrum Disorder
- (2014) Logan K. Wink et al. JOURNAL OF CLINICAL PSYCHIATRY
- N-acetylcysteine in psychiatry: current therapeutic evidence and potential mechanisms of action
- (2014) Olivia Dean et al. JOURNAL OF PSYCHIATRY & NEUROSCIENCE
- Clustering autism: using neuroanatomical differences in 26 mouse models to gain insight into the heterogeneity
- (2014) J Ellegood et al. MOLECULAR PSYCHIATRY
- A phase 2 trial of the GSK-3 inhibitor tideglusib in progressive supranuclear palsy
- (2014) Eduardo Tolosa et al. MOVEMENT DISORDERS
- Synaptic, transcriptional and chromatin genes disrupted in autism
- (2014) Silvia De Rubeis et al. NATURE
- Memantine Effects on Verbal Memory in Fragile X-associated Tremor/Ataxia Syndrome (FXTAS): a Double-Blind Brain Potential Study
- (2014) Jin-Chen Yang et al. NEUROPSYCHOPHARMACOLOGY
- Gastrointestinal Symptoms in Autism Spectrum Disorder: A Meta-analysis
- (2014) B. O. McElhanon et al. PEDIATRICS
- Plasma oxytocin concentrations and OXTR polymorphisms predict social impairments in children with and without autism spectrum disorder
- (2014) K. J. Parker et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Functional recovery with recombinant human IGF1 treatment in a mouse model of Rett Syndrome
- (2014) Jorge Castro et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Safety, pharmacokinetics, and preliminary assessment of efficacy of mecasermin (recombinant human IGF-1) for the treatment of Rett syndrome
- (2014) O. S. Khwaja et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Sulforaphane treatment of autism spectrum disorder (ASD)
- (2014) K. Singh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Histone deacetylase inhibition rescues structural and functional brain deficits in a mouse model of Kabuki syndrome
- (2014) H. T. Bjornsson et al. Science Translational Medicine
- An Update on Medication Management of Behavioral Disorders in Autism
- (2014) Danielle A. Baribeau et al. Current Psychiatry Reports
- A pilot controlled trial of insulin-like growth factor-1 in children with Phelan-McDermid syndrome
- (2014) Alexander Kolevzon et al. Molecular Autism
- Microbiota Modulate Behavioral and Physiological Abnormalities Associated with Neurodevelopmental Disorders
- (2013) Elaine Y. Hsiao et al. CELL
- Prenatal Valproate Exposure and Risk of Autism Spectrum Disorders and Childhood Autism
- (2013) Jakob Christensen et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Autism and Dietary Therapy
- (2013) Martha R. Herbert et al. JOURNAL OF CHILD NEUROLOGY
- Memantine for Fragile X–Associated Tremor/Ataxia Syndrome
- (2013) Andreea L. Seritan et al. JOURNAL OF CLINICAL PSYCHIATRY
- Methylomic analysis of monozygotic twins discordant for autism spectrum disorder and related behavioural traits
- (2013) C C Y Wong et al. MOLECULAR PSYCHIATRY
- Elevated maternal C-reactive protein and autism in a national birth cohort
- (2013) A S Brown et al. MOLECULAR PSYCHIATRY
- Microbiota is essential for social development in the mouse
- (2013) L Desbonnet et al. MOLECULAR PSYCHIATRY
- Common DNA methylation alterations in multiple brain regions in autism
- (2013) C Ladd-Acosta et al. MOLECULAR PSYCHIATRY
- Attention to eyes is present but in decline in 2–6-month-old infants later diagnosed with autism
- (2013) Warren Jones et al. NATURE
- SHANK3 and IGF1 restore synaptic deficits in neurons from 22q13 deletion syndrome patients
- (2013) Aleksandr Shcheglovitov et al. NATURE
- Diet rapidly and reproducibly alters the human gut microbiome
- (2013) Lawrence A. David et al. NATURE
- Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs
- (2013) S Hong Lee et al. NATURE GENETICS
- Lovastatin Corrects Excess Protein Synthesis and Prevents Epileptogenesis in a Mouse Model of Fragile X Syndrome
- (2013) Emily K. Osterweil et al. NEURON
- Tuberous Sclerosis Complex Surveillance and Management: Recommendations of the 2012 International Tuberous Sclerosis Complex Consensus Conference
- (2013) Darcy A. Krueger et al. PEDIATRIC NEUROLOGY
- Glycogen synthase kinase-3 inhibitors: Rescuers of cognitive impairments
- (2013) Margaret K. King et al. PHARMACOLOGY & THERAPEUTICS
- Multiplex Genome Engineering Using CRISPR/Cas Systems
- (2013) L. Cong et al. SCIENCE
- Ketone bodies as signaling metabolites
- (2013) John C. Newman et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Association Between Early-Onset Parkinson Disease and 22q11.2 Deletion Syndrome
- (2013) Nancy J. Butcher et al. JAMA Neurology
- Baseline Factors Predicting Placebo Response to Treatment in Children and Adolescents With Autism Spectrum Disorders
- (2013) Bryan H. King et al. JAMA Pediatrics
- A Randomized Controlled Pilot Trial of Oral N-Acetylcysteine in Children with Autism
- (2012) Antonio Y. Hardan et al. BIOLOGICAL PSYCHIATRY
- Molecular Therapies for Tuberous Sclerosis and Neurofibromatosis
- (2012) David Neal Franz et al. Current Neurology and Neuroscience Reports
- Psychostimulants for ADHD-like symptoms in individuals with autism spectrum disorders
- (2012) Samuele Cortese et al. Expert Review of Neurotherapeutics
- Mutations inSYNGAP1Cause Intellectual Disability, Autism, and a Specific Form of Epilepsy by Inducing Haploinsufficiency
- (2012) Martin H. Berryer et al. HUMAN MUTATION
- 1H-MRS in autism spectrum disorders: a systematic meta-analysis
- (2012) Jonathan C. Ipser et al. METABOLIC BRAIN DISEASE
- Cerebral folate receptor autoantibodies in autism spectrum disorder
- (2012) R E Frye et al. MOLECULAR PSYCHIATRY
- Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice
- (2012) Peter T. Tsai et al. NATURE
- Chronic Pharmacological mGlu5 Inhibition Corrects Fragile X in Adult Mice
- (2012) Aubin Michalon et al. NEURON
- Autism After Infection, Febrile Episodes, and Antibiotic Use During Pregnancy: An Exploratory Study
- (2012) H. O. Atladottir et al. PEDIATRICS
- Rescue of dendritic spine phenotype in Fmr1 KO mice with the mGluR5 antagonist AFQ056/Mavoglurant
- (2012) Andreea S. Pop et al. PSYCHOPHARMACOLOGY
- Interactions Between the Microbiota and the Immune System
- (2012) L. V. Hooper et al. SCIENCE
- Reversal of Disease-Related Pathologies in the Fragile X Mouse Model by Selective Activation of GABAB Receptors with Arbaclofen
- (2012) C. Henderson et al. Science Translational Medicine
- Effects of STX209 (Arbaclofen) on Neurobehavioral Function in Children and Adults with Fragile X Syndrome: A Randomized, Controlled, Phase 2 Trial
- (2012) E. M. Berry-Kravis et al. Science Translational Medicine
- Social impairment in children with obsessive compulsive disorder: Do comorbid problems of inattention and hyperactivity matter?
- (2012) Kerri L. Kim et al. Journal of Obsessive-Compulsive and Related Disorders
- A randomised controlled trial of bumetanide in the treatment of autism in children
- (2012) E Lemonnier et al. Translational Psychiatry
- Oxytocin and vasopressin in the human brain: social neuropeptides for translational medicine
- (2011) Andreas Meyer-Lindenberg et al. NATURE REVIEWS NEUROSCIENCE
- Autistic Traits Below the Clinical Threshold: Re-examining the Broader Autism Phenotype in the 21st Century
- (2011) E. Sucksmith et al. NEUROPSYCHOLOGY REVIEW
- The Toll-Like Receptor 2 Pathway Establishes Colonization by a Commensal of the Human Microbiota
- (2011) J. L. Round et al. SCIENCE
- The diuretic bumetanide decreases autistic behaviour in five infants treated during 3 months with no side effects
- (2010) Eric Lemonnier et al. ACTA PAEDIATRICA
- Consensus Statement: Chromosomal Microarray Is a First-Tier Clinical Diagnostic Test for Individuals with Developmental Disabilities or Congenital Anomalies
- (2010) David T. Miller et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Research Domain Criteria (RDoC): Toward a New Classification Framework for Research on Mental Disorders
- (2010) Thomas Insel et al. AMERICAN JOURNAL OF PSYCHIATRY
- Open-label riluzole in fragile X syndrome
- (2010) Craig A. Erickson et al. BRAIN RESEARCH
- Antidepressant Drug Effects and Depression Severity
- (2010) Jay C. Fournier et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Functional impact of global rare copy number variation in autism spectrum disorders
- (2010) Dalila Pinto et al. NATURE
- fMRI evidence of neural abnormalities in the subcortical face processing system in ASD
- (2010) Natalia M. Kleinhans et al. NEUROIMAGE
- Clinical Genetic Testing for Patients With Autism Spectrum Disorders
- (2010) Y. Shen et al. PEDIATRICS
- Assessing and reporting heterogeneity in treatment effects in clinical trials: a proposal
- (2010) David M Kent et al. Trials
- Cytokines and CNS Development
- (2009) Benjamin E. Deverman et al. NEURON
- Divalproex Sodium vs Placebo for the Treatment of Irritability in Children and Adolescents with Autism Spectrum Disorders
- (2009) Eric Hollander et al. NEUROPSYCHOPHARMACOLOGY
- Aripiprazole in the Treatment of Irritability in Children and Adolescents With Autistic Disorder
- (2009) R. Owen et al. PEDIATRICS
- History of the ketogenic diet
- (2008) James W. Wheless EPILEPSIA
- Pioglitazone reduces tumor necrosis factor-α serum concentration and mRNA expression of adipose tissue in hypercholesterolemic rabbits
- (2008) Zhi-hong Wu et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- The ketogenic diet for the treatment of childhood epilepsy: a randomised controlled trial
- (2008) Elizabeth G Neal et al. LANCET NEUROLOGY
- Pregnenolone sulfate in the brain: A controversial neurosteroid
- (2007) Michael Schumacher et al. NEUROCHEMISTRY INTERNATIONAL
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now