Effects of STX209 (Arbaclofen) on Neurobehavioral Function in Children and Adults with Fragile X Syndrome: A Randomized, Controlled, Phase 2 Trial

Reversal of Disease-Related Pathologies in the Fragile X Mouse Model by Selective Activation of GABAB Receptors with Arbaclofen

(2012) C. Henderson et al.   Science Translational Medicine

Amygdala Regulation of Fear and Emotionality in Fragile X Syndrome

(2011) Jose Luis Olmos-Serrano et al.   DEVELOPMENTAL NEUROSCIENCE

Epigenetic Modification of the FMR1 Gene in Fragile X Syndrome Is Associated with Differential Response to the mGluR5 Antagonist AFQ056

(2011) S. Jacquemont et al.   Science Translational Medicine

Toward Fulfilling the Promise of Molecular Medicine in Fragile X Syndrome

(2010) Dilja D. Krueger et al.   Annual Review of Medicine

Emerging Pharmacotherapies for Neurodevelopmental Disorders

(2010) Daniel Z. Wetmore et al.   JOURNAL OF DEVELOPMENTAL AND BEHAVIORAL PEDIATRICS

Clinical assessment of DSM-IV anxiety disorders in fragile X syndrome: prevalence and characterization

(2010) Lisa Cordeiro et al.   Journal of Neurodevelopmental Disorders

Defective GABAergic Neurotransmission and Pharmacological Rescue of Neuronal Hyperexcitability in the Amygdala in a Mouse Model of Fragile X Syndrome

(2010) J. L. Olmos-Serrano et al.   JOURNAL OF NEUROSCIENCE

Fragile X: Leading the way for targeted treatments in autism

(2010) Lulu W. Wang et al.   Neurotherapeutics

Characterization and reversal of synaptic defects in the amygdala in a mouse model of fragile X syndrome

(2010) A. Suvrathan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapamycin for treating Tuberous sclerosis and Autism spectrum disorders

(2010) Dan Ehninger et al.   TRENDS IN MOLECULAR MEDICINE

Aberrant Brain Activation During Gaze Processing in Boys With Fragile X Syndrome

(2008) Christa Watson et al.   ARCHIVES OF GENERAL PSYCHIATRY

Identification of small molecules rescuing fragile X syndrome phenotypes in Drosophila

(2008) Shuang Chang et al.   Nature Chemical Biology

Rescue of behavioral phenotype and neuronal protrusion morphology in Fmr1 KO mice

(2008) Femke M.S. de Vrij et al.   NEUROBIOLOGY OF DISEASE

Advances in the Treatment of Fragile X Syndrome

(2008) R. J. Hagerman et al.   PEDIATRICS