Randomised controlled trial of simvastatin treatment for autism in young children with neurofibromatosis type 1 (SANTA)

A Proton Magnetic Resonance Spectroscopic Study in Autism Spectrum Disorder Using a 3-Tesla Clinical Magnetic Resonance Imaging (MRI) System: The Anterior Cingulate Cortex and the Left Cerebellum

(2017) Hiromichi Ito et al.   JOURNAL OF CHILD NEUROLOGY

Testing the excitation/inhibition imbalance hypothesis in a mouse model of the autism spectrum disorder: in vivo neurospectroscopy and molecular evidence for regional phenotypes

(2017) Joana Gonçalves et al.   Molecular Autism

Strength of ERK1/2 MAPK Activation Determines Its Effect on Myelin and Axonal Integrity in the Adult CNS

(2016) Akihiro Ishii et al.   JOURNAL OF NEUROSCIENCE

Randomized placebo-controlled study of lovastatin in children with neurofibromatosis type 1

(2016) Jonathan M. Payne et al.   NEUROLOGY

GABA deficiency in NF1

(2016) Inês R. Violante et al.   NEUROLOGY

Quantification of γ-aminobutyric acid (GABA) in1H MRS volumes composed heterogeneously of grey and white matter

(2016) Mark Mikkelsen et al.   NMR IN BIOMEDICINE

Statins and the brain: New perspective for old drugs

(2016) Q. Ling et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Disease Burden and Symptom Structure of Autism in Neurofibromatosis Type 1

(2016) Stephanie M. Morris et al.   JAMA Psychiatry

A randomized placebo-controlled lovastatin trial for neurobehavioral function in neurofibromatosis I

(2016) Carrie E. Bearden et al.   Annals of Clinical and Translational Neurology

Comprehensive RNA Analysis of the NF1 Gene in Classically Affected NF1 Affected Individuals Meeting NIH Criteria has High Sensitivity and Mutation Negative Testing is Reassuring in Isolated Cases With Pigmentary Features Only

(2016) D.G. Evans et al.   EBioMedicine

Resting state functional MRI reveals abnormal network connectivity in neurofibromatosis 1

(2015) Steffie N. Tomson et al.   HUMAN BRAIN MAPPING

Plasma protein biomarkers of Alzheimer’s disease endophenotypes in asymptomatic older twins: early cognitive decline and regional brain volumes

(2015) S J Kiddle et al.   Translational Psychiatry

Social learning and amygdala disruptions in Nf1 mice are rescued by blocking p21-activated kinase

(2014) Andrei I Molosh et al.   NATURE NEUROSCIENCE

Statins in neurological disorders: An overview and update

(2014) Anna Maria Malfitano et al.   PHARMACOLOGICAL RESEARCH

Increasing the power of the Mann-Whitney test in randomized experiments through flexible covariate adjustment

(2014) Karel Vermeulen et al.   STATISTICS IN MEDICINE

Reduced Cerebral Arterial Spin-Labeled Perfusion in Children with Neurofibromatosis Type 1

(2013) K.W. Yeom et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

Lovastatin improves impaired synaptic plasticity and phasic alertness in patients with neurofibromatosis type 1

(2013) Florian Mainberger et al.   BMC Neurology

GABA deficit in the visual cortex of patients with neurofibromatosis type 1: genotype–phenotype correlations and functional impact

(2013) Inês R. Violante et al.   BRAIN

Simvastatin for cognitive deficits and behavioural problems in patients with neurofibromatosis type 1 (NF1-SIMCODA): a randomised, placebo-controlled trial

(2013) Thijs van der Vaart et al.   LANCET NEUROLOGY

Neurofibromatosis Type 1 and Autism Spectrum Disorder

(2013) S. Garg et al.   PEDIATRICS

Nf1 Loss and Ras Hyperactivation in Oligodendrocytes Induce NOS-Driven Defects in Myelin and Vasculature

(2013) Debra A. Mayes et al.   Cell Reports

Longitudinal changes in brain function related to statin use

(2012) Lori Beason-Held et al.   Alzheimers & Dementia

Autism and other psychiatric comorbidity in neurofibromatosis type 1: evidence from a population-based study

(2012) SHRUTI GARG et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Current practice in the use of MEGA-PRESS spectroscopy for the detection of GABA

(2012) Paul G. Mullins et al.   NEUROIMAGE

Lovastatin regulates brain spontaneous low-frequency brain activity in Neurofibromatosis type 1

(2012) Camille Chabernaud et al.   NEUROSCIENCE LETTERS

Alterations in White Matter Microstructure in Neurofibromatosis-1

(2012) Katherine H. Karlsgodt et al.   PLoS One

Lovastatin as Treatment for Neurocognitive Deficits in Neurofibromatosis Type 1: Phase I Study

(2011) Maria T. Acosta et al.   PEDIATRIC NEUROLOGY

Birth incidence and prevalence of tumor-prone syndromes: Estimates from a UK family genetic register service

(2010) D.G. Evans et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Altered white matter integrity and development in children with autism: A combined voxel-based morphometry and diffusion imaging study

(2010) Paola Mengotti et al.   BRAIN RESEARCH BULLETIN

Reduced thalamic 18F-flurodeoxyglucose retention in adults with neurofibromatosis type 1

(2009) Ralph Buchert et al.   NUCLEAR MEDICINE COMMUNICATIONS

Neurofibromin Regulation of ERK Signaling Modulates GABA Release and Learning

(2008) Yijun Cui et al.   CELL

Diffusion Tensor Imaging of Frontal Lobe in Autism Spectrum Disorder

(2008) S. K. Sundaram et al.   CEREBRAL CORTEX

Effect of Simvastatin on Cognitive Functioning in Children With Neurofibromatosis Type 1

(2008) Lianne C. Krab   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Open-Label Treatment Trial of Lithium to Target the Underlying Defect in Fragile X Syndrome

(2008) Elizabeth Berry-Kravis et al.   JOURNAL OF DEVELOPMENTAL AND BEHAVIORAL PEDIATRICS