Autism Spectrum Disorder as a Brain-Gut-Microbiome Axis Disorder

Pilot study of probiotic/colostrum supplementation on gut function in children with autism and gastrointestinal symptoms

(2019) Megan R. Sanctuary et al.   PLoS One

Altered Gut Microbiota in Chinese Children With Autism Spectrum Disorders

(2019) Bingjie Ma et al.   Frontiers in Cellular and Infection Microbiology

Autism Spectrum Disorder (ASD) with and without Mental Regression is Associated with Changes in the Fecal Microbiota

(2019) Julio Plaza-Díaz et al.   Nutrients

Leveraging Human Microbiome Features to Diagnose and Stratify Children with Irritable Bowel Syndrome

(2019) Emily B. Hollister et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

The Relationship Among Gastrointestinal Symptoms, Problem Behaviors, and Internalizing Symptoms in Children and Adolescents With Autism Spectrum Disorder

(2019) Bradley J. Ferguson et al.   Frontiers in Psychiatry

Efficacy of different probiotic protocols in irritable bowel syndrome

(2019) Ding Liang et al.   MEDICINE

Long-term benefit of Microbiota Transfer Therapy on autism symptoms and gut microbiota

(2019) Dae-Wook Kang et al.   Scientific Reports

Fecal and Mucosal Microbiota Profiling in Irritable Bowel Syndrome and Inflammatory Bowel Disease

(2019) Alessandra Lo Presti et al.   Frontiers in Microbiology

Probiotics for Gastrointestinal Symptoms and Quality of Life in Autism: A Placebo-Controlled Pilot Trial

(2019) L. Eugene Arnold et al.   JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY

Intestinal serotonin and fluoxetine exposure modulate bacterial colonization in the gut

(2019) Thomas C. Fung et al.   Nature Microbiology

Analysis of gut microbiome, nutrition and immune status in autism spectrum disorder: a case-control study in Ecuador

(2019) María Fernanda Zurita et al.   Gut Microbes

The Gut Microbiota Mediates the Anti-Seizure Effects of the Ketogenic Diet

(2018) Christine A. Olson et al.   CELL

Gut Microbial Dysbiosis in Indian Children with Autism Spectrum Disorders

(2018) Joby Pulikkan et al.   MICROBIAL ECOLOGY

Comprehensive Nutritional and Dietary Intervention for Autism Spectrum Disorder—A Randomized, Controlled 12-Month Trial

(2018) James Adams et al.   Nutrients

The Gut Microbiome in Adult and Pediatric Functional Gastrointestinal Disorders

(2018) Andrea Shin et al.   Clinical Gastroenterology and Hepatology

Diet Can Impact Microbiota Composition in Children With Autism Spectrum Disorder

(2018) Kirsten Berding et al.   Frontiers in Neuroscience

Otitis media, antibiotics, and risk of autism spectrum disorder

(2018) Theresa Wimberley et al.   Autism Research

The protective effects of fecal microbiota transplantation in an experimental model of necrotizing enterocolitis

(2018) Christian Prado et al.   JOURNAL OF PEDIATRIC SURGERY

Mechanisms Underlying Microbial-Mediated Changes in Social Behavior in Mouse Models of Autism Spectrum Disorder

(2018) Martina Sgritta et al.   NEURON

Gut microbiota composition and functional changes in inflammatory bowel disease and irritable bowel syndrome

(2018) Arnau Vich Vila et al.   Science Translational Medicine

Gut Microbiota Features in Young Children With Autism Spectrum Disorders

(2018) Lorena Coretti et al.   Frontiers in Microbiology

Ketogenic diet versus gluten free casein free diet in autistic children: a case-control study

(2017) Omnia El-Rashidy et al.   METABOLIC BRAIN DISEASE

Ketogenic diets improve behaviors associated with autism spectrum disorder in a sex-specific manner in the EL mouse

(2017) David N. Ruskin et al.   PHYSIOLOGY & BEHAVIOR

Sex-related alterations of gut microbiota composition in the BTBR mouse model of autism spectrum disorder

(2017) Lorena Coretti et al.   Scientific Reports

Blockade of interleukin-6 receptor in the periphery promotes rapid and sustained antidepressant actions: a possible role of gut–microbiota–brain axis

(2017) J-c Zhang et al.   Translational Psychiatry

New evidences on the altered gut microbiota in autism spectrum disorders

(2017) Francesco Strati et al.   Microbiome

Microbiota Transfer Therapy alters gut ecosystem and improves gastrointestinal and autism symptoms: an open-label study

(2017) Dae-Wook Kang et al.   Microbiome

Microbiota-related Changes in Bile Acid & Tryptophan Metabolism are Associated with Gastrointestinal Dysfunction in a Mouse Model of Autism

(2017) Anna V. Golubeva et al.   EBioMedicine

Ketogenic diet improves behaviors in a maternal immune activation model of autism spectrum disorder

(2017) David N. Ruskin et al.   PLoS One

Maternal obese-type gut microbiota differentially impact cognition, anxiety and compulsive behavior in male and female offspring in mice

(2017) Annadora J. Bruce-Keller et al.   PLoS One

Microbial Reconstitution Reverses Maternal Diet-Induced Social and Synaptic Deficits in Offspring

(2016) Shelly A. Buffington et al.   CELL

Linking the Human Gut Microbiome to Inflammatory Cytokine Production Capacity

(2016) Melanie Schirmer et al.   CELL

The Central Nervous System and the Gut Microbiome

(2016) Gil Sharon et al.   CELL

Gastrointestinal symptoms and behavioral problems in preschoolers with Autism Spectrum Disorder

(2016) Francesca Fulceri et al.   DIGESTIVE AND LIVER DISEASE

Annexin A2, autoimmunity, anxiety and depression

(2016) R. Weiss et al.   JOURNAL OF AUTOIMMUNITY

Minocycline as Adjunctive Treatment to Risperidone in Children with Autistic Disorder: A Randomized, Double-Blind Placebo-Controlled Trial

(2016) Ali Ghaleiha et al.   JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY

Serotonin transporter variant drives preventable gastrointestinal abnormalities in development and function

(2016) Kara Gross Margolis et al.   JOURNAL OF CLINICAL INVESTIGATION

Reported History of Developmental Regression and Restricted, Repetitive Behaviors in Children with Autism Spectrum Disorders

(2016) Catherine C. Bradley et al.   JOURNAL OF DEVELOPMENTAL AND BEHAVIORAL PEDIATRICS

Metabolomic Modeling To Monitor Host Responsiveness to Gut Microbiota Manipulation in the BTBRT+tf/j Mouse

(2016) Matthias S. Klein et al.   JOURNAL OF PROTEOME RESEARCH

The intestinal epithelial barrier: a therapeutic target?

(2016) Matthew A. Odenwald et al.   Nature Reviews Gastroenterology & Hepatology

The effect of ketogenic diet in an animal model of autism induced by prenatal exposure to valproic acid

(2016) Kamila Castro et al.   NUTRITIONAL NEUROSCIENCE

Ketogenic diet exposure during the juvenile period increases social behaviors and forebrain neural activation in adult Engrailed 2 null mice

(2016) Jessica L. Verpeut et al.   PHYSIOLOGY & BEHAVIOR

Maternal immune activation: Implications for neuropsychiatric disorders

(2016) M. L. Estes et al.   SCIENCE

The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring

(2016) G. B. Choi et al.   SCIENCE

Natural history of the infant gut microbiome and impact of antibiotic treatment on bacterial strain diversity and stability

(2016) Moran Yassour et al.   Science Translational Medicine

Effect of gluten free diet on gastrointestinal and behavioral indices for children with autism spectrum disorders: a randomized clinical trial

(2016) Faezeh Ghalichi et al.   World Journal of Pediatrics

A randomized, placebo-controlled trial of d-cycloserine for the enhancement of social skills training in autism spectrum disorders

(2016) Noha F. Minshawi et al.   Molecular Autism

Ketogenic diet modifies the gut microbiota in a murine model of autism spectrum disorder

(2016) Christopher Newell et al.   Molecular Autism

Adult Hippocampal Neurogenesis Is Regulated by the Microbiome

(2015) Ebere S. Ogbonnaya et al.   BIOLOGICAL PSYCHIATRY

The interaction between maternal immune activation and alpha 7 nicotinic acetylcholine receptor in regulating behaviors in the offspring

(2015) Wei-Li Wu et al.   BRAIN BEHAVIOR AND IMMUNITY

Indigenous Bacteria from the Gut Microbiota Regulate Host Serotonin Biosynthesis

(2015) Jessica M. Yano et al.   CELL

Th17 Cell Induction by Adhesion of Microbes to Intestinal Epithelial Cells

(2015) Koji Atarashi et al.   CELL

Dynamics and Stabilization of the Human Gut Microbiome during the First Year of Life

(2015) Fredrik Bäckhed et al.   Cell Host & Microbe

Gut microbes promote colonic serotonin production through an effect of short-chain fatty acids on enterochromaffin cells

(2015) Christopher S. Reigstad et al.   FASEB JOURNAL

Diversity of Duodenal and Rectal Microbiota in Biopsy Tissues and Luminal Contents in Healthy Volunteers

(2015) Gangping Li et al.   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

Microbiota Controls the Homeostasis of Glial Cells in the Gut Lamina Propria

(2015) Panagiotis S. Kabouridis et al.   NEURON

The microbiota regulates type 2 immunity through ROR t+ T cells

(2015) C. Ohnmacht et al.   SCIENCE

Simultaneous fecal microbial and metabolite profiling enables accurate classification of pediatric irritable bowel syndrome

(2015) Vijay Shankar et al.   Microbiome

Comparison of Fecal Microbiota in Children with Autism Spectrum Disorders and Neurotypical Siblings in the Simons Simplex Collection

(2015) Joshua S. Son et al.   PLoS One

The Ketogenic Diet Modifies Social and Metabolic Alterations Identified in the Prenatal Valproic Acid Model of Autism Spectrum Disorder

(2014) Younghee Ahn et al.   DEVELOPMENTAL NEUROSCIENCE

Ketogenic diets, mitochondria, and neurological diseases

(2014) Lindsey B. Gano et al.   JOURNAL OF LIPID RESEARCH

Maternal immune activation and abnormal brain development across CNS disorders

(2014) Irene Knuesel et al.   Nature Reviews Neurology

Are ‘leaky gut’ and behavior associated with gluten and dairy containing diet in children with autism spectrum disorders?

(2014) Fernando Navarro et al.   NUTRITIONAL NEUROSCIENCE

Gastrointestinal Symptoms in Autism Spectrum Disorder: A Meta-analysis

(2014) B. O. McElhanon et al.   PEDIATRICS

Absence of the gut microbiota enhances anxiety-like behavior and neuroendocrine response to acute stress in rats

(2014) Michèle Crumeyrolle-Arias et al.   PSYCHONEUROENDOCRINOLOGY

Reversal of autism-like behaviors and metabolism in adult mice with single-dose antipurinergic therapy

(2014) J C Naviaux et al.   Translational Psychiatry

Microbiota Modulate Behavioral and Physiological Abnormalities Associated with Neurodevelopmental Disorders

(2013) Elaine Y. Hsiao et al.   CELL

Autism and Dietary Therapy

(2013) Martha R. Herbert et al.   JOURNAL OF CHILD NEUROLOGY

Increased Proportions of Bifidobacterium and the Lactobacillus Group and Loss of Butyrate-Producing Bacteria in Inflammatory Bowel Disease

(2013) W. Wang et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Microbiota is essential for social development in the mouse

(2013) L Desbonnet et al.   MOLECULAR PSYCHIATRY

Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells

(2013) Yukihiro Furusawa et al.   NATURE

Diet rapidly and reproducibly alters the human gut microbiome

(2013) Lawrence A. David et al.   NATURE

Intestinal microbiota influence the early postnatal development of the enteric nervous system

(2013) J. Collins et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Modeling Autism by SHANK Gene Mutations in Mice

(2013) Yong-hui Jiang et al.   NEURON

Comorbidity Clusters in Autism Spectrum Disorders: An Electronic Health Record Time-Series Analysis

(2013) Finale Doshi-Velez et al.   PEDIATRICS

Antipurinergic Therapy Corrects the Autism-Like Features in the Poly(IC) Mouse Model

(2013) Robert K. Naviaux et al.   PLoS One

Ketogenic Diet Improves Core Symptoms of Autism in BTBR Mice

(2013) David N. Ruskin et al.   PLoS One

Reduced Incidence of Prevotella and Other Fermenters in Intestinal Microflora of Autistic Children

(2013) Dae-Wook Kang et al.   PLoS One

Fecal Microbiota and Metabolome of Children with Autism and Pervasive Developmental Disorder Not Otherwise Specified

(2013) Maria De Angelis et al.   PLoS One

Increased abundance of Sutterella spp. and Ruminococcus torques in feces of children with autism spectrum disorder

(2013) Lv Wang et al.   Molecular Autism

Molecular Characterisation of Gastrointestinal Microbiota of Children With Autism (With and Without Gastrointestinal Dysfunction) and Their Neurotypical Siblings

(2012) Shakuntla V. Gondalia et al.   Autism Research

Gastrointestinal Dysfunction in Autism: Parental Report, Clinical Evaluation, and Associated Factors

(2012) Phillip Gorrindo et al.   Autism Research

Gut Microbial Products Regulate Murine Gastrointestinal Motility via Toll-Like Receptor 4 Signaling

(2012) Mallappa Anitha et al.   GASTROENTEROLOGY

Urinary p-cresol in autism spectrum disorder

(2012) Antonio M. Persico et al.   NEUROTOXICOLOGY AND TERATOLOGY

Autism After Infection, Febrile Episodes, and Antibiotic Use During Pregnancy: An Exploratory Study

(2012) H. O. Atladottir et al.   PEDIATRICS

Modeling an autism risk factor in mice leads to permanent immune dysregulation

(2012) E. Y. Hsiao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Urinaryp-cresol is elevated in small children with severe autism spectrum disorder

(2011) Laura Altieri et al.   BIOMARKERS

Prosocial effects of oxytocin and clinical evidence for its therapeutic potential

(2011) Nadine Striepens et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Impaired Uptake of Serotonin by Platelets From Patients With Irritable Bowel Syndrome Correlates With Duodenal Immune Activation

(2011) Stephen Foley et al.   GASTROENTEROLOGY

Gastrointestinal Microbiome Signatures of Pediatric Patients With Irritable Bowel Syndrome

(2011) Delphine M. Saulnier et al.   GASTROENTEROLOGY

Oxytocin and vasopressin in the human brain: social neuropeptides for translational medicine

(2011) Andreas Meyer-Lindenberg et al.   NATURE REVIEWS NEUROSCIENCE

The relationship between the neuromodulator adenosine and behavioral symptoms of autism

(2011) Susan A. Masino et al.   NEUROSCIENCE LETTERS

Impaired Carbohydrate Digestion and Transport and Mucosal Dysbiosis in the Intestines of Children with Autism and Gastrointestinal Disturbances

(2011) Brent L. Williams et al.   PLoS One

Pyrosequencing study of fecal microflora of autistic and control children

(2010) Sydney M. Finegold et al.   ANAEROBE

Association of Hospitalization for Infection in Childhood With Diagnosis of Autism Spectrum Disorders

(2010) Hjördís Ósk Atladóttir et al.   ARCHIVES OF PEDIATRICS & ADOLESCENT MEDICINE

Social peers rescue autism-relevant sociability deficits in adolescent mice

(2010) Mu Yang et al.   Autism Research

Evaluation, Diagnosis, and Treatment of Gastrointestinal Disorders in Individuals With ASDs: A Consensus Report

(2010) Timothy Buie et al.   PEDIATRICS

Succession of microbial consortia in the developing infant gut microbiome

(2010) J. E. Koenig et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sleep problems in autism spectrum disorders: Prevalence, nature, & possible biopsychosocial aetiologies

(2009) Amanda L. Richdale et al.   SLEEP MEDICINE REVIEWS

Human colonic microbiota associated with diet, obesity and weight loss

(2008) S H Duncan et al.   INTERNATIONAL JOURNAL OF OBESITY