Mini-Review: Mitochondrial dysfunction and chemotherapy-induced neuropathic pain

Duloxetine Attenuates Paclitaxel-Induced Peripheral Nerve Injury by Inhibiting p53-Related Pathways

(2020) Yuting Lu et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Calmangafodipir Reduces Sensory Alterations and Prevents Intraepidermal Nerve Fibers Loss in a Mouse Model of Oxaliplatin Induced Peripheral Neurotoxicity

(2020) Annalisa Canta et al.   Antioxidants

[EXPRESS] Peripheral and central oxidative stress in chemotherapy-induced neuropathic pain

(2019) Hyun Soo Shim et al.   Molecular Pain

[EXPRESS] Bortezomib-induced aerobic glycolysis contributes to chemotherapy-induced painful peripheral neuropathy

(2019) Talylor Ludman et al.   Molecular Pain

Neuroprotective Role of Selected Antioxidant Agents in Preventing Cisplatin-Induced Damage of Human Neurons In Vitro

(2019) Jelena Popović et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Cell-specific role of HDAC6 in chemotherapy-induced mechanical allodynia and loss of intraepidermal nerve fibers

(2019) Jiacheng Ma et al.   PAIN

Axonal Transport and Mitochondrial Function in Neurons

(2019) Amrita Mandal et al.   Frontiers in Cellular Neuroscience

Therapeutic benefits of maintaining mitochondrial integrity and calcium homeostasis by forced expression of Hsp27 in chemotherapy-induced peripheral neuropathy

(2019) Virendra Bhagawan Chine et al.   NEUROBIOLOGY OF DISEASE

PTEN-Induced Putative Kinase 1 (PINK1)/Parkin-Mediated Mitophagy Protects PC12 Cells Against Cisplatin-Induced Neurotoxicity

(2019) Yao Zhang et al.   MEDICAL SCIENCE MONITOR

Mitochondrial morphology provides a mechanism for energy buffering at synapses

(2019) Guadalupe C. Garcia et al.   Scientific Reports

Protective Effect of a Mitochondria-Targeted Peptide against the Development of Chemotherapy-Induced Peripheral Neuropathy in Mice

(2018) Satoshi Toyama et al.   ACS Chemical Neuroscience

Mitochondrial membrane potential

(2018) Ljubava D. Zorova et al.   ANALYTICAL BIOCHEMISTRY

N-acetylcysteine versus progesterone on the cisplatin-induced peripheral neurotoxicity

(2018) S.M. Zaki et al.   FOLIA MORPHOLOGICA

Liu Jun Zi Tang—A Potential, Multi-Herbal Complementary Therapy for Chemotherapy-Induced Neurotoxicity

(2018) Chun-Tang Chiou et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Rosmarinic Acid Mitigates Mitochondrial Dysfunction and Spinal Glial Activation in Oxaliplatin-induced Peripheral Neuropathy

(2018) Aparna Areti et al.   MOLECULAR NEUROBIOLOGY

Mitochondria at the neuronal presynapse in health and disease

(2018) Michael J. Devine et al.   NATURE REVIEWS NEUROSCIENCE

Orally active Epac inhibitor reverses mechanical allodynia and loss of intraepidermal nerve fibers in a mouse model of chemotherapy-induced peripheral neuropathy

(2018) Pooja Singhmar et al.   PAIN

Oxygen radicals, nitric oxide, and peroxynitrite: Redox pathways in molecular medicine

(2018) Rafael Radi   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oxidative Phosphorylation: A Target for Novel Therapeutic Strategies Against Ovarian Cancer

(2018) Amruta Nayak et al.   Cancers

Monoclonal Antibody Targeting the Matrix Metalloproteinase 9 Prevents and Reverses Paclitaxel-Induced Peripheral Neuropathy in Mice

(2018) Raquel Tonello et al.   JOURNAL OF PAIN

Melatonin prevents mitochondrial dysfunction and promotes neuroprotection by inducing autophagy during oxaliplatin-evoked peripheral neuropathy

(2017) Aparna Areti et al.   JOURNAL OF PINEAL RESEARCH

Depletion of Mitofusin-2 Causes Mitochondrial Damage in Cisplatin-Induced Neuropathy

(2017) Ilja Bobylev et al.   MOLECULAR NEUROBIOLOGY

Cisplatin induces mitochondrial deficits in Drosophila larval segmental nerve

(2017) Jewel L. Podratz et al.   NEUROBIOLOGY OF DISEASE

HDAC6 inhibition effectively reverses chemotherapy-induced peripheral neuropathy

(2017) Karen Krukowski et al.   PAIN

Paclitaxel-induced painful neuropathy is associated with changes in mitochondrial bioenergetics, glycolysis, and an energy deficit in dorsal root ganglia neurons

(2017) Natalie A. Duggett et al.   PAIN

Carvedilol prevents functional deficits in peripheral nerve mitochondria of rats with oxaliplatin-evoked painful peripheral neuropathy

(2017) Aparna Areti et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The Interplay of Axonal Energy Homeostasis and Mitochondrial Trafficking and Anchoring

(2017) Zu-Hang Sheng   TRENDS IN CELL BIOLOGY

Pharmacological augmentation of nicotinamide phosphoribosyltransferase (NAMPT) protects against paclitaxel-induced peripheral neuropathy

(2017) Peter M LoCoco et al.   eLife

Inhibition of Mitochondrial p53 Accumulation by PFT-μ Prevents Cisplatin-Induced Peripheral Neuropathy

(2017) Magdalena A. Maj et al.   Frontiers in Molecular Neuroscience

Rosmarinic Acid Protects against Inflammation and Cardiomyocyte Apoptosis during Myocardial Ischemia/Reperfusion Injury by Activating Peroxisome Proliferator-Activated Receptor Gamma

(2017) Jichun Han et al.   Frontiers in Pharmacology

Human histone deacetylase 6 shows strong preference for tubulin dimers over assembled microtubules

(2017) Lubica Skultetyova et al.   Scientific Reports

MitoVitE, a mitochondria-targeted antioxidant, limits paclitaxel-induced oxidative stress and mitochondrial damage in vitro , and paclitaxel-induced mechanical hypersensitivity in a rat pain model

(2016) B. McCormick et al.   BRITISH JOURNAL OF ANAESTHESIA

Structural Basis for Induction of Peripheral Neuropathy by Microtubule-Targeting Cancer Drugs

(2016) J. A. Smith et al.   CANCER RESEARCH

Effect of the SOD mimetic MnL4 on in vitro and in vivo oxaliplatin toxicity: Possible aid in chemotherapy induced neuropathy

(2016) Lorenzo Di Cesare Mannelli et al.   FREE RADICAL BIOLOGY AND MEDICINE

Cisplatin Toxicity in Dorsal Root Ganglion Neurons Is Relieved by Meclizine via Diminution of Mitochondrial Compromise and Improved Clearance of DNA Damage

(2016) Murat F. Gorgun et al.   MOLECULAR NEUROBIOLOGY

Methylcobalamin ameliorates neuropathic pain induced by vincristine in rats

(2016) Jing Xu et al.   Molecular Pain

Oxidative stress in the development, maintenance and resolution of paclitaxel-induced painful neuropathy

(2016) Natalie A. Duggett et al.   NEUROSCIENCE

Mitochondrial Dynamics Decrease Prior to Axon Degeneration Induced by Vincristine and are Partially Rescued by Overexpressed cytNmnat1

(2016) Gregory W. Berbusse et al.   Frontiers in Cellular Neuroscience

Evaluation of multi-neuroprotective effects of erythropoietin using cisplatin induced peripheral neurotoxicity model

(2015) Nivin Sharawy et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

Disorders of phospholipid metabolism: an emerging class of mitochondrial disease due to defects in nuclear genes

(2015) Ya-Wen Lu et al.   Frontiers in Genetics

Activity-Driven Local ATP Synthesis Is Required for Synaptic Function

(2014) Vidhya Rangaraju et al.   CELL

Mitochondria-Targeted Peptide Reverses Mitochondrial Dysfunction and Cognitive Deficits in Sepsis-Associated Encephalopathy

(2014) Jing Wu et al.   MOLECULAR NEUROBIOLOGY

Genetic Inactivation and Pharmacological Blockade of Sigma-1 Receptors Prevent Paclitaxel-Induced Sensory-Nerve Mitochondrial Abnormalities and Neuropathic Pain in Mice

(2014) Francisco R Nieto et al.   Molecular Pain

Mitotoxicity in distal symmetrical sensory peripheral neuropathies

(2014) Gary J. Bennett et al.   Nature Reviews Neurology

Ixabepilone-induced mitochondria and sensory axon loss in breast cancer patients

(2014) Gigi J. Ebenezer et al.   Annals of Clinical and Translational Neurology

Characterization of Acute and Chronic Neuropathies Induced by Oxaliplatin in Mice and Differential Effects of a Novel Mitochondria-targeted Antioxidant on the Neuropathies

(2013) Satoshi Toyama et al.   ANESTHESIOLOGY

Targeting mitochondrial cardiolipin and the cytochromec/cardiolipin complex to promote electron transport and optimize mitochondrial ATP synthesis

(2013) A V Birk et al.   BRITISH JOURNAL OF PHARMACOLOGY

Bortezomib-induced neuropathy: Axonal membrane depolarization precedes development of neuropathy

(2013) Saiko Nasu et al.   CLINICAL NEUROPHYSIOLOGY

Nutraceuticals and chemotherapy induced peripheral neuropathy (CIPN): A systematic review

(2013) Janet M. Schloss et al.   CLINICAL NUTRITION

Treatment of oxaliplatin-induced peripheral neuropathy by intravenous mangafodipir

(2013) Romain Coriat et al.   JOURNAL OF CLINICAL INVESTIGATION

Mitochondrial swelling and microtubule depolymerization are associated with energy depletion in axon degeneration

(2013) J.Y. Park et al.   NEUROSCIENCE

Bioenergetic deficits in peripheral nerve sensory axons during chemotherapy-induced neuropathic pain resulting from peroxynitrite-mediated post-translational nitration of mitochondrial superoxide dismutase

(2013) Kali Janes et al.   PAIN

Pathobiology of cancer chemotherapy-induced peripheral neuropathy (CIPN)

(2013) Yaqin Han et al.   Frontiers in Pharmacology

Mitotoxicity and bortezomib-induced chronic painful peripheral neuropathy

(2012) H. Zheng et al.   EXPERIMENTAL NEUROLOGY

Oxaliplatin-Induced Neuropathy: Oxidative Stress as Pathological Mechanism. Protective Effect of Silibinin

(2012) Lorenzo Di Cesare Mannelli et al.   JOURNAL OF PAIN

Effects of mitochondrial poisons on the neuropathic pain produced by the chemotherapeutic agents, paclitaxel and oxaliplatin

(2012) Wen Hua Xiao et al.   PAIN

Oxidative Stress and Antioxidant Defense

(2012) Esra Birben et al.   World Allergy Organization Journal

Functional deficits in peripheral nerve mitochondria in rats with paclitaxel- and oxaliplatin-evoked painful peripheral neuropathy

(2011) Huaien Zheng et al.   EXPERIMENTAL NEUROLOGY

Manganese Superoxide Dismutase: Guardian of the Powerhouse

(2011) Aaron K. Holley et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Role of Drp1, a Key Mitochondrial Fission Protein, in Neuropathic Pain

(2011) L. F. Ferrari et al.   JOURNAL OF NEUROSCIENCE

Mitochondrial abnormality in sensory, but not motor, axons in paclitaxel-evoked painful peripheral neuropathy in the rat

(2011) W.H. Xiao et al.   NEUROSCIENCE

Characterization of oxaliplatin-induced chronic painful peripheral neuropathy in the rat and comparison with the neuropathy induced by paclitaxel

(2011) W.H. Xiao et al.   NEUROSCIENCE

Paclitaxel therapy potentiates cold hyperalgesia in streptozotocin-induced diabetic rats through enhanced mitochondrial reactive oxygen species production and TRPA1 sensitization

(2011) David André Barrière et al.   PAIN

Global Inhibition of Reactive Oxygen Species (ROS) Inhibits Paclitaxel-Induced Painful Peripheral Neuropathy

(2011) Mehmet Fidanboylu et al.   PLoS One

Chemotherapy-induced neuropathic pain

(2011) Paul Farquhar-Smith   Current Opinion in Supportive and Palliative Care

Mitochondria and Neuroplasticity

(2010) Aiwu Cheng et al.   ASN Neuro

Metabolism of acetyl-l-carnitine for energy and neurotransmitter synthesis in the immature rat brain

(2010) Susanna Scafidi et al.   JOURNAL OF NEUROCHEMISTRY

Cisplatin induced Mitochondrial DNA damage in dorsal root ganglion neurons

(2010) Jewel L. Podratz et al.   NEUROBIOLOGY OF DISEASE

SOD2-Mediated Effects Induced by WR1065 and Low-Dose Ionizing Radiation on Micronucleus Formation in RKO Human Colon Carcinoma Cells

(2010) Jeffrey S. Murley et al.   RADIATION RESEARCH

Chemical and molecular mechanisms of antioxidants: experimental approaches and model systems

(2009) Jian-Ming Lü et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Central Sensitization: A Generator of Pain Hypersensitivity by Central Neural Plasticity

(2009) Alban Latremoliere et al.   JOURNAL OF PAIN

Ameliorative effects of amiloride and pralidoxime in chronic constriction injury and vincristine induced painful neuropathy in rats

(2008) Arunachalam Muthuraman et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Oxaliplatin Acts on IB4-Positive Nociceptors to Induce an Oxidative Stress-Dependent Acute Painful Peripheral Neuropathy

(2008) Elizabeth K. Joseph et al.   JOURNAL OF PAIN

Prevention of paclitaxel-evoked painful peripheral neuropathy by acetyl-l-carnitine: Effects on axonal mitochondria, sensory nerve fiber terminal arbors, and cutaneous Langerhans cells

(2007) Hai Wei Jin et al.   EXPERIMENTAL NEUROLOGY

Chemotherapy-evoked neuropathic pain: Abnormal spontaneous discharge in A-fiber and C-fiber primary afferent neurons and its suppression by acetyl-l-carnitine

(2007) Wen Hua Xiao et al.   PAIN