Rosmarinic Acid Protects against Inflammation and Cardiomyocyte Apoptosis during Myocardial Ischemia/Reperfusion Injury by Activating Peroxisome Proliferator-Activated Receptor Gamma

Differential Roles of Peroxisome Proliferator-Activated Receptor-αand Receptor-γon Renal Crystal Formation in Hyperoxaluric Rodents

(2016) Kazumi Taguchi et al.   PPAR Research

Fucoidan reduces inflammatory response in a rat model of hepatic ischemia–reperfusion injury

(2015) Xiao-jing Li et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Anti-Warburg effect of rosmarinic acid via miR-155 in gastric cancer cells

(2015) Zhou Li et al.   Drug Design Development and Therapy

Hydrogen sulfide alleviates cardiac contractile dysfunction in an Akt2-knockout murine model of insulin resistance: role of mitochondrial injury and apoptosis

(2014) Nan Hu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Insights from systems pharmacology into cardiovascular drug discovery and therapy

(2014) Peng Li et al.   BMC Systems Biology

Rosmarinic Acid Extract for Antioxidant, Antiallergic, and α-Glucosidase Inhibitory Activities, Isolated by Supramolecular Technique and Solvent Extraction from Perilla Leaves

(2014) Fengxian Zhu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Cardioprotection against Ischemia/Reperfusion by Licochalcone B in Isolated Rat Hearts

(2014) Jichun Han et al.   Oxidative Medicine and Cellular Longevity

Telmisartan Attenuates Colon Inflammation, Oxidative Perturbations and Apoptosis in a Rat Model of Experimental Inflammatory Bowel Disease

(2014) Hany H. Arab et al.   PLoS One

Exploiting polypharmacology for drug target deconvolution

(2014) Taranjit Singh Gujral et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effect of peroxisome proliferator-activated receptor gamma agonist on heart of rabbits with acute myocardial ischemia/reperfusion injury

(2014) Qian Hu et al.   Asian Pacific Journal of Tropical Medicine

Erratum to “15-Deoxy-γ12,14-prostaglandin J2 Reduces Liver Impairment in a Model of ConA-Induced Acute Hepatic Inflammation by Activation of PPARγand Reduction in NF-κB Activity”

(2014) Kan Chen et al.   PPAR Research

History of Gestational Diabetes Mellitus and Future Risk of Atherosclerosis in Mid‐life: The Coronary Artery Risk Development in Young Adults Study

(2014) Erica P. Gunderson et al.   Journal of the American Heart Association

Coptisine protects rat heart against myocardial ischemia/reperfusion injury by suppressing myocardial apoptosis and inflammation

(2013) Jing Guo et al.   ATHEROSCLEROSIS

Telmisartan protects against microvascular dysfunction during myocardial ischemia/reperfusion injury by activation of peroxisome proliferator-activated receptor gamma

(2013) Xiao-Cong Zeng et al.   BMC Cardiovascular Disorders

Systems pharmacology in drug discovery and therapeutic insight for herbal medicines

(2013) Chao Huang et al.   BRIEFINGS IN BIOINFORMATICS

Systems pharmacology strategies for drug discovery and combination with applications to cardiovascular diseases

(2013) Peng Li et al.   JOURNAL OF ETHNOPHARMACOLOGY

The effects of dietary fatty acids on the postprandial triglyceride-rich lipoprotein/apoB48 receptor axis in human monocyte/macrophage cells

(2013) Lourdes M. Varela et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Pioglitazone attenuates myocardial ischemia-reperfusion injury via up-regulation of ERK and COX-2

(2013) Wang   BioScience Trends

Adiposity has differing associations with incident coronary heart disease and mortality in the Scottish population: cross-sectional surveys with follow-up

(2012) J W Hotchkiss et al.   INTERNATIONAL JOURNAL OF OBESITY

PPAR-γ as a therapeutic target in cardiovascular disease: evidence and uncertainty

(2012) Janice V. Huang et al.   JOURNAL OF LIPID RESEARCH

Systems-based approaches to cardiovascular disease

(2012) W. Robb MacLellan et al.   Nature Reviews Cardiology

Effect of Plant Polyphenols on Ischemia-Reperfusion Injury of the Isolated rat Heart and Vessels

(2012) Z. Brosková et al.   PHYTOTHERAPY RESEARCH

A Systematic Prediction of Multiple Drug-Target Interactions from Chemical, Genomic, and Pharmacological Data

(2012) Hua Yu et al.   PLoS One

Polypharmacology: drug discovery for the future

(2012) A Srinivas Reddy et al.   Expert Review of Clinical Pharmacology

Novel Computational Approaches to Polypharmacology as a Means to Define Responses to Individual Drugs

(2011) Lei Xie et al.   Annual Review of Pharmacology and Toxicology

The natural antioxidant rosmarinic acid spontaneously penetrates membranes to inhibit lipid peroxidation in situ

(2011) Ophélie Fadel et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Telmisartan, a dual ARB/partial PPAR-γ agonist, protects myocardium from ischaemic reperfusion injury in experimental diabetes

(2011) S. N. Goyal et al.   DIABETES OBESITY & METABOLISM

Cat's Whiskers Tea (Orthosiphon Stamineus) Extract Inhibits Growth of Colon Tumor in Nude Mice and Angiogenesis in Endothelial Cells via Suppressing VEGFR Phosphorylation

(2011) Mohamed B. Khadeer Ahamed et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

MicroRNAs Add a New Dimension to Cardiovascular Disease

(2010) Eric M. Small et al.   CIRCULATION

Predicting Polypharmacology by Binding Site Similarity: From Kinases to the Protein Universe

(2010) Francesca Milletti et al.   Journal of Chemical Information and Modeling

Peroxisome proliferator-activated receptors and angiogenesis

(2009) F. Biscetti et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Reaction of Rosmarinic Acid with Nitrite Ions in Acidic Conditions: Discovery of Nitro- and Dinitrorosmarinic Acids as New Anti-HIV-1 Agents

(2008) Mélanie Dubois et al.   JOURNAL OF MEDICINAL CHEMISTRY