Oxidative Phosphorylation: A Target for Novel Therapeutic Strategies Against Ovarian Cancer
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Oxidative Phosphorylation: A Target for Novel Therapeutic Strategies Against Ovarian Cancer
Authors
Keywords
-
Journal
Cancers
Volume 10, Issue 9, Pages 337
Publisher
MDPI AG
Online
2018-09-18
DOI
10.3390/cancers10090337
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Expression of glycolytic enzymes in ovarian cancers and evaluation of the glycolytic pathway as a strategy for ovarian cancer treatment
- (2018) Chrysi Xintaropoulou et al. BMC CANCER
- Atovaquone enhances doxorubicin’s efficacy via inhibiting mitochondrial respiration and STAT3 in aggressive thyroid cancer
- (2018) Zhuo Lv et al. JOURNAL OF BIOENERGETICS AND BIOMEMBRANES
- An inhibitor of oxidative phosphorylation exploits cancer vulnerability
- (2018) Jennifer R. Molina et al. NATURE MEDICINE
- Mutations in the SWI/SNF complex induce a targetable dependence on oxidative phosphorylation in lung cancer
- (2018) Yonathan Lissanu Deribe et al. NATURE MEDICINE
- p53 and metabolism: from mechanism to therapeutics
- (2018) Fernando M. Simabuco et al. Oncotarget
- Biological and metabolic effects of IACS-010759, an OxPhos inhibitor, on chronic lymphocytic leukemia cells
- (2018) Hima V. Vangapandu et al. Oncotarget
- Oxidative stress via inhibition of the mitochondrial electron transport and Nrf-2-mediated anti-oxidative response regulate the cytotoxic activity of plumbagin
- (2018) Arvinder Kapur et al. Scientific Reports
- TRAP1 Regulation of Cancer Metabolism: Dual Role as Oncogene or Tumor Suppressor
- (2018) Danilo Matassa et al. Genes
- Metabolic Symbiosis and Immunomodulation: How Tumor Cell-Derived Lactate May Disturb Innate and Adaptive Immune Responses
- (2018) Alexandre Morrot et al. Frontiers in Oncology
- Phenyl butyrate inhibits pyruvate dehydrogenase kinase 1 and contributes to its anti-cancer effect
- (2017) Wen Zhang et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Synthesis and antitumor activity of novel 2, 3-didithiocarbamate substituted naphthoquinones as inhibitors of pyruvate kinase M2 isoform
- (2017) Xianling Ning et al. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
- Discovery and Optimization of Potent, Cell-Active Pyrazole-Based Inhibitors of Lactate Dehydrogenase (LDH)
- (2017) Ganesha Rai et al. JOURNAL OF MEDICINAL CHEMISTRY
- Pyruvate kinase M2 is a poor prognostic marker of and a therapeutic target in ovarian cancer
- (2017) Tai-Kuang Chao et al. PLoS One
- Pilot study demonstrating metabolic and anti-proliferative effects of in vivo anti-oxidant supplementation with N-Acetylcysteine in Breast Cancer
- (2017) Daniel Monti et al. SEMINARS IN ONCOLOGY
- Bioenergetic Adaptations in Chemoresistant Ovarian Cancer Cells
- (2017) Sajad Dar et al. Scientific Reports
- Molecular features of biguanides required for targeting of mitochondrial respiratory complex I and activation of AMP-kinase
- (2016) Hannah R. Bridges et al. BMC BIOLOGY
- Olaparib maintenance therapy in patients with platinum-sensitive, relapsed serous ovarian cancer and aBRCAmutation: Overall survival adjusted for postprogression poly(adenosine diphosphate ribose) polymerase inhibitor therapy
- (2016) Ursula A. Matulonis et al. CANCER
- Oxidative metabolism drives inflammation-induced platinum resistance in human ovarian cancer
- (2016) D S Matassa et al. CELL DEATH AND DIFFERENTIATION
- Molecular Alterations of TP53 are a Defining Feature of Ovarian High-Grade Serous Carcinoma
- (2016) Russell Vang et al. INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY
- Overall survival in patients with platinum-sensitive recurrent serous ovarian cancer receiving olaparib maintenance monotherapy: an updated analysis from a randomised, placebo-controlled, double-blind, phase 2 trial
- (2016) Jonathan A Ledermann et al. LANCET ONCOLOGY
- The anti-malarial atovaquone increases radiosensitivity by alleviating tumour hypoxia
- (2016) Thomas M. Ashton et al. Nature Communications
- Repurposing atovaquone: Targeting mitochondrial complex III and OXPHOS to eradicate cancer stem cells
- (2016) Marco Fiorillo et al. Oncotarget
- Plumbagin Inhibits Prostate Carcinogenesis in Intact and Castrated PTEN Knockout Mice via Targeting PKC , Stat3, and Epithelial-to-Mesenchymal Transition Markers
- (2015) B. B. Hafeez et al. Cancer Prevention Research
- Tumors and Mitochondrial Respiration: A Neglected Connection
- (2015) Andrea Viale et al. CANCER RESEARCH
- Mitochondrial Genome Acquisition Restores Respiratory Function and Tumorigenic Potential of Cancer Cells without Mitochondrial DNA
- (2015) An S. Tan et al. Cell Metabolism
- Development of pyruvate dehydrogenase kinase inhibitors in medicinal chemistry with particular emphasis as anticancer agents
- (2015) Shao-Lin Zhang et al. DRUG DISCOVERY TODAY
- HSulf-1 deficiency dictates a metabolic reprograming of glycolysis and TCA cycle in ovarian cancer
- (2015) Susmita Mondal et al. Oncotarget
- Mitochondrial mass, a new metabolic biomarker for stem-like cancer cells: Understanding WNT/FGF-driven anabolic signaling
- (2015) Rebecca Lamb et al. Oncotarget
- Mitochondrial biogenesis is required for the anchorage-independent survival and propagation of stem-like cancer cells
- (2015) Arianna De Luca et al. Oncotarget
- Cancer Metabolism: New Validated Targets for Drug Discovery
- (2015) Federica Sotgia et al. Oncotarget
- Cancer stem cells from epithelial ovarian cancer patients privilege oxidative phosphorylation, and resist glucose deprivation
- (2015) Anna Pastò et al. Oncotarget
- Effects of metformin and other biguanides on oxidative phosphorylation in mitochondria
- (2014) Hannah R. Bridges et al. BIOCHEMICAL JOURNAL
- Ovarian tumor-initiating cells display a flexible metabolism
- (2014) Angela S. Anderson et al. EXPERIMENTAL CELL RESEARCH
- Sites of Superoxide and Hydrogen Peroxide Production by Muscle Mitochondria Assessedex Vivounder Conditions Mimicking Rest and Exercise
- (2014) Renata L. S. Goncalves et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Olaparib maintenance therapy in patients with platinum-sensitive relapsed serous ovarian cancer: a preplanned retrospective analysis of outcomes by BRCA status in a randomised phase 2 trial
- (2014) Jonathan Ledermann et al. LANCET ONCOLOGY
- Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function
- (2014) Andrea Viale et al. NATURE
- Bioenergetic Analysis of Ovarian Cancer Cell Lines: Profiling of Histological Subtypes and Identification of a Mitochondria-Defective Cell Line
- (2014) Usawadee Dier et al. PLoS One
- BRCA1 Induces Major Energetic Metabolism Reprogramming in Breast Cancer Cells
- (2014) Maud Privat et al. PLoS One
- Inhibitors of Mutant IDH for the Treatment of Cancer
- (2014) Ahmed F. Abdel-Magid ACS Medicinal Chemistry Letters
- Novel Mutation in Cytochrome B of Plasmodium falciparum in One of Two Atovaquone-Proguanil Treatment Failures in Travelers Returning From Same Site in Nigeria
- (2014) M. M. Plucinski et al. Open Forum Infectious Diseases
- Transformation of the Fallopian Tube Secretory Epithelium Leads to High-Grade Serous Ovarian Cancer in Brca;Tp53;Pten Models
- (2013) Ruth Perets et al. CANCER CELL
- Overexpression of Glucose Transporter-1 (GLUT-1) Predicts Poor Prognosis in Epithelial Ovarian Cancer
- (2013) Hanbyoul Cho et al. CANCER INVESTIGATION
- Oncogenes and inflammation rewire host energy metabolism in the tumor microenvironment
- (2013) Ubaldo E Martinez-Outschoorn et al. CELL CYCLE
- Association of overexpression of hexokinase II with chemoresistance in epithelial ovarian cancer
- (2013) Dong Hoon Suh et al. CLINICAL AND EXPERIMENTAL MEDICINE
- Metabolic changes during ovarian cancer progression as targets for sphingosine treatment
- (2013) Angela S. Anderson et al. EXPERIMENTAL CELL RESEARCH
- Metformin intake is associated with better survival in ovarian cancer
- (2012) Sanjeev Kumar et al. CANCER
- Plumbagin inhibits prostate cancer development in TRAMP mice via targeting PKC , Stat3 and neuroendocrine markers
- (2012) B. B. Hafeez et al. CARCINOGENESIS
- Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism
- (2012) Haoqiang Ying et al. CELL
- Mechanisms of free radical-induced damage to DNA
- (2012) Miral Dizdaroglu et al. FREE RADICAL RESEARCH
- Erratum: Integrated genomic analyses of ovarian carcinoma
- (2012) The Cancer Genome Atlas Research Network NATURE
- Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis
- (2012) Dimitrios Anastasiou et al. Nature Chemical Biology
- Olaparib Maintenance Therapy in Platinum-Sensitive Relapsed Ovarian Cancer
- (2012) Jonathan Ledermann et al. NEW ENGLAND JOURNAL OF MEDICINE
- Evidence for a stromal-epithelial “lactate shuttle” in human tumors
- (2011) Diana Whitaker-Menezes et al. CELL CYCLE
- The impact of diabetes on survival in women with ovarian cancer
- (2011) Arvind Bakhru et al. GYNECOLOGIC ONCOLOGY
- Use of metformin and the risk of ovarian cancer: A case–control analysis
- (2011) Michael Bodmer et al. GYNECOLOGIC ONCOLOGY
- Molecular pathogenesis and extraovarian origin of epithelial ovarian cancer—Shifting the paradigm
- (2011) Robert J. Kurman et al. HUMAN PATHOLOGY
- TP53 mutations in serous tubal intraepithelial carcinoma and concurrent pelvic high-grade serous carcinoma-evidence supporting the clonal relationship of the two lesions
- (2011) Elisabetta Kuhn et al. JOURNAL OF PATHOLOGY
- Respiratory competent mitochondria in human ovarian and peritoneal cancer
- (2011) Hwee Ying Lim et al. MITOCHONDRION
- Relationship of Type II Diabetes and Metformin Use to Ovarian Cancer Progression, Survival, and Chemosensitivity
- (2011) Iris L. Romero et al. OBSTETRICS AND GYNECOLOGY
- The Origin and Pathogenesis of Epithelial Ovarian Cancer: A Proposed Unifying Theory
- (2010) Robert J. Kurman et al. AMERICAN JOURNAL OF SURGICAL PATHOLOGY
- Are All Pelvic (Nonuterine) Serous Carcinomas of Tubal Origin?
- (2010) Christopher G. Przybycin et al. AMERICAN JOURNAL OF SURGICAL PATHOLOGY
- Stromal caveolin-1 levels predict early DCIS progression to invasive breast cancer
- (2010) Agnieszka K. Witkiewicz et al. CANCER BIOLOGY & THERAPY
- Superoxide is the major reactive oxygen species regulating autophagy
- (2009) Y Chen et al. CELL DEATH AND DIFFERENTIATION
- Pathogenesis of Ovarian Cancer
- (2009) Robert J. Kurman et al. INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY
- Evaluation of SubstitutedN,N′-Diarylsulfonamides as Activators of the Tumor Cell Specific M2 Isoform of Pyruvate Kinase
- (2009) Matthew B. Boxer et al. JOURNAL OF MEDICINAL CHEMISTRY
- Tyrosine Phosphorylation Inhibits PKM2 to Promote the Warburg Effect and Tumor Growth
- (2009) T. Hitosugi et al. Science Signaling
- How mitochondria produce reactive oxygen species
- (2008) Michael P. Murphy BIOCHEMICAL JOURNAL
- Thiol chemistry and specificity in redox signaling
- (2008) Christine C. Winterbourn et al. FREE RADICAL BIOLOGY AND MEDICINE
- Pyruvate kinase M2 is a phosphotyrosine-binding protein
- (2008) Heather R. Christofk et al. NATURE
- The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
- (2008) Heather R. Christofk et al. NATURE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started