LncRNA‐HOTAIR promotes endothelial cell pyroptosis by regulating the miR‐22/NLRP3 axis in hyperuricaemia

Research Progress on the Role of Inflammasomes in Kidney Disease

(2020) Kun Chi et al.   MEDIATORS OF INFLAMMATION

Role of Inflammasomes in Kidney Diseases via Both Canonical and Non-canonical Pathways

(2020) Huiling Xiang et al.   Frontiers in Cell and Developmental Biology

TNF‐α/HMGB1 inflammation signalling pathway regulates pyroptosis during liver failure and acute kidney injury

(2020) Yao Wang et al.   CELL PROLIFERATION

High Concentrations of Uric Acid and Angiotensin II Act Additively to Produce Endothelial Injury

(2020) Quan Hong et al.   MEDIATORS OF INFLAMMATION

The mechanism of Arhalofenate in alleviating hyperuricemia―Activating PPARγ thereby reducing caspase‐1 activity

(2020) Guihong Wang et al.   DRUG DEVELOPMENT RESEARCH

Inflammasomes and Cell Death: Common Pathways in Microparticle Diseases

(2020) Maryam Rashidi et al.   TRENDS IN MOLECULAR MEDICINE

LncRNA HOTAIR Promotes Neuronal Damage Through Facilitating NLRP3 Mediated-Pyroptosis Activation in Parkinson’s Disease via Regulation of miR-326/ELAVL1 Axis

(2020) Qian Zhang et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Long noncoding RNA Hotair facilitates retinal endothelial cell dysfunction in diabetic retinopathy

(2020) Di Zhao et al.   CLINICAL SCIENCE

New Insights into the Mechanisms of Pyroptosis and Implications for Diabetic Kidney Disease

(2020) Jinwen Lin et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Long noncoding RNA LINC00339 promotes renal tubular epithelial pyroptosis by regulating the miR-22-3p/NLRP3 axis in calcium oxalate-induced kidney stone

(2019) Zhengyao Song et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Cell Death in the Kidney

(2019) Giovanna Priante et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Pyroptotic Cell Death Effector Gasdermin D Is Activated by Gout-Associated Uric Acid Crystals but Is Dispensable for Cell Death and IL-1β Release

(2019) Maryam Rashidi et al.   JOURNAL OF IMMUNOLOGY

Dysregulated expression but redundant function of the long non-coding RNA HOTAIR in diabetic kidney disease

(2019) Syamantak Majumder et al.   DIABETOLOGIA

Comprehensive analysis of long noncoding RNA (lncRNA)-chromatin interactions reveals lncRNA functions dependent on binding diverse regulatory elements

(2019) Guanxiong Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Gasdermin D and pyroptosis in acute kidney injury

(2019) Wulf Tonnus et al.   KIDNEY INTERNATIONAL

Recent advances in inflammasome biology

(2018) David E Place et al.   CURRENT OPINION IN IMMUNOLOGY

Inflammasome, Inflammation, and Tissue Homeostasis

(2018) Vijay A.K. Rathinam et al.   TRENDS IN MOLECULAR MEDICINE

The lncRNA H19 positively affects the tumorigenic properties of glioblastoma cells and contributes to NKD1 repression through the recruitment of EZH2 on its promoter

(2018) Barbara Fazi et al.   Oncotarget

Monosodium Urate Crystals Activate the Inflammasome in Primary Progressive Multiple Sclerosis

(2018) Federica Piancone et al.   Frontiers in Immunology

miR-22 in Smooth Muscle Cells

(2018) Zhan-Peng Huang et al.   CIRCULATION

LncRNA HOX transcript antisense RNA accelerated kidney injury induced by urine-derived sepsis through the miR-22/high mobility group box 1 pathway

(2018) Jun Shen et al.   LIFE SCIENCES

LncRNA HOTAIR regulates HIF-1α/AXL signaling through inhibition of miR-217 in renal cell carcinoma

(2017) Quan Hong et al.   Cell Death & Disease

LincRNA-Gm4419 knockdown ameliorates NF-κB/NLRP3 inflammasome-mediated inflammation in diabetic nephropathy

(2017) Hong Yi et al.   Cell Death & Disease

Management of Gout: A Systematic Review in Support of an American College of Physicians Clinical Practice Guideline

(2016) Paul G. Shekelle et al.   ANNALS OF INTERNAL MEDICINE

Integrative Transcriptome Analyses of Metabolic Responses in Mice Define Pivotal LncRNA Metabolic Regulators

(2016) Ling Yang et al.   Cell Metabolism

Mechanisms of long noncoding RNA function in development and disease

(2016) Sandra U. Schmitz et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Long Noncoding RNAs in Cardiovascular Pathology, Diagnosis, and Therapy

(2016) Christian Bär et al.   CIRCULATION

Caspase-1 Inflammasome Activation Mediates Homocysteine-Induced Pyrop-Apoptosis in Endothelial CellsNovelty and Significance

(2016) Hang Xi et al.   CIRCULATION RESEARCH

Long non-coding RNA XIST exerts oncogenic functions in human nasopharyngeal carcinoma by targeting miR-34a-5p

(2016) Peng Song et al.   GENE

An NLRP3-specific inflammasome inhibitor attenuates crystal-induced kidney fibrosis in mice

(2016) Isis Ludwig-Portugall et al.   KIDNEY INTERNATIONAL

An endoplasmic reticulum stress-regulated lncRNA hosting a microRNA megacluster induces early features of diabetic nephropathy

(2016) Mitsuo Kato et al.   Nature Communications

Targeting the Notch-regulated non-coding RNA TUG1 for glioma treatment

(2016) Keisuke Katsushima et al.   Nature Communications

Molecular mechanisms regulating NLRP3 inflammasome activation

(2015) Eun-Kyeong Jo et al.   Cellular & Molecular Immunology

High Concentrations of Uric Acid Inhibit Angiogenesis via Regulation of the Krüppel-Like Factor 2-Vascular Endothelial Growth Factor-A Axis by miR-92a

(2015) Shandong Yu et al.   CIRCULATION JOURNAL

Long non-coding RNA MALAT1 regulates hyperglycaemia induced inflammatory process in the endothelial cells

(2015) Prasanth Puthanveetil et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

(2015) Jianjin Shi et al.   NATURE

A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases

(2015) Rebecca C Coll et al.   NATURE MEDICINE

Hyperuricemia-induced inflammasome and kidney diseases

(2015) Yoshitaka Isaka et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Long noncoding RNA Hotair mediated angiogenesis in nasopharyngeal carcinoma by direct and indirect signaling pathways

(2015) Wei-ming Fu et al.   Oncotarget

Human NLRP3 inflammasome senses multiple types of bacterial RNAs

(2014) Wenwen Sha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Oncogenic MicroRNA miR-22 Targets the TET2 Tumor Suppressor to Promote Hematopoietic Stem Cell Self-Renewal and Transformation

(2013) Su Jung Song et al.   Cell Stem Cell

The role of uric acid in the pathogenesis of human cardiovascular disease

(2013) Mehmet Kanbay et al.   HEART

Emerging functional and mechanistic paradigms of mammalian long non-coding RNAs

(2012) V. A. Moran et al.   NUCLEIC ACIDS RESEARCH

Gout

(2011) Tuhina Neogi   NEW ENGLAND JOURNAL OF MEDICINE

Association of Uric Acid With Change in Kidney Function in Healthy Normotensive Individuals

(2010) Gianni Bellomo et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Evolution and Functions of Long Noncoding RNAs

(2009) Chris P. Ponting et al.   CELL

The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis

(2009) Luigi Franchi et al.   NATURE IMMUNOLOGY

The conundrum of hyperuricemia, metabolic syndrome, and renal disease

(2008) Takahiko Nakagawa et al.   Internal and Emergency Medicine