Monosodium Urate Crystals Activate the Inflammasome in Primary Progressive Multiple Sclerosis

Soluble Uric Acid Activates the NLRP3 Inflammasome

(2017) Tarcio Teodoro Braga et al.   Scientific Reports

TH17-Driven Inflammation is Present in All Clinical Forms of Multiple Sclerosis; Disease Quiescence is Associated with Gata3-Expressing Cells

(2017) M. Saresella et al.   European Journal of Inflammation

Interleukin 18 (IL-18) as a target for immune intervention

(2016) Sebastian Wawrocki et al.   ACTA BIOCHIMICA POLONICA

Expression of IL-1β in rhesus EAE and MS lesions is mainly induced in the CNS itself

(2016) Saskia Maria Burm et al.   Journal of Neuroinflammation

T cell–intrinsic ASC critically promotes TH17-mediated experimental autoimmune encephalomyelitis

(2016) Bradley N Martin et al.   NATURE IMMUNOLOGY

A Fluorescent Reporter Mouse for Inflammasome Assembly Demonstrates an Important Role for Cell-Bound and Free ASC Specks during In Vivo Infection

(2016) Te-Chen Tzeng et al.   Cell Reports

A basic overview of multiple sclerosis immunopathology

(2015) N. Grigoriadis et al.   EUROPEAN JOURNAL OF NEUROLOGY

Caspase-8 as an Effector and Regulator of NLRP3 Inflammasome Signaling

(2015) Christina Antonopoulos et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Uric acid in relapsing–remitting multiple sclerosis: a 2-year longitudinal study

(2015) Marcello Moccia et al.   JOURNAL OF NEUROLOGY

Advances in T Helper 17 Cell Biology: Pathogenic Role and Potential Therapy in Multiple Sclerosis

(2015) Elisabetta Volpe et al.   MEDIATORS OF INFLAMMATION

Serum uric acid level in patients with relapsing-remitting multiple sclerosis

(2013) Fereshteh Ashtari et al.   JOURNAL OF CLINICAL NEUROSCIENCE

ASC Controls IFN-  Levels in an IL-18-Dependent Manner in Caspase-1-Deficient Mice Infected with Francisella novicida

(2013) R. Pierini et al.   JOURNAL OF IMMUNOLOGY

Interleukin-18 and IL-18 Binding Protein

(2013) Charles A. Dinarello et al.   Frontiers in Immunology

Serum levels of interleukin (IL)-18, IL-23 and IL-17 in Chinese patients with multiple sclerosis

(2012) Ying-Chun Chen et al.   JOURNAL OF NEUROIMMUNOLOGY

Serum uric acid levels in patients with multiple sclerosis: a meta-analysis

(2012) Bo Liu et al.   NEUROLOGICAL RESEARCH

Interferon-  Therapy Against EAE Is Effective Only When Development of the Disease Depends on the NLRP3 Inflammasome

(2012) M. Inoue et al.   Science Signaling

Interleukin-18, From Neuroinflammation to Alzheimers Disease

(2011) Paola Bossu et al.   CURRENT PHARMACEUTICAL DESIGN

Heterogeneity versus homogeneity of multiple sclerosis

(2011) Fumitaka Sato et al.   Expert Review of Clinical Immunology

Th17 Cell, the New Player of Neuroinflammatory Process in Multiple Sclerosis

(2011) F. Jadidi-Niaragh et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

NLRP3 Plays a Critical Role in the Development of Experimental Autoimmune Encephalomyelitis by Mediating Th1 and Th17 Responses

(2010) D. Gris et al.   JOURNAL OF IMMUNOLOGY

Dimethylfumarate inhibits microglial and astrocytic inflammation by suppressing the synthesis of nitric oxide, IL-1β, TNF-α and IL-6 in an in-vitro model of brain inflammation

(2010) Henrik Wilms et al.   Journal of Neuroinflammation

Mutant superoxide dismutase 1-induced IL-1  accelerates ALS pathogenesis

(2010) F. Meissner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inflammasomes and autoimmunity

(2010) Patrick J. Shaw et al.   TRENDS IN MOLECULAR MEDICINE

Uric Acid Is a Danger Signal Activating NALP3 Inflammasome in Lung Injury Inflammation and Fibrosis

(2009) Pamela Gasse et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Increase of uric acid and purine compounds in biological fluids of multiple sclerosis patients

(2009) Angela M. Amorini et al.   CLINICAL BIOCHEMISTRY

Cerebrospinal fluid and serum uric acid levels in patients with multiple sclerosis

(2009) Irena Dujmovic et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

The analysis of IL-1 beta and its naturally occurring inhibitors in multiple sclerosis: The elevation of IL-1 receptor antagonist and IL-1 receptor type II after steroid therapy

(2009) Irena Dujmovic et al.   JOURNAL OF NEUROIMMUNOLOGY

T helper cell type 1 (Th1), Th2 and Th17 responses to myelin basic protein and disease activity in multiple sclerosis

(2008) Chris J. Hedegaard et al.   IMMUNOLOGY

The NALP3 inflammasome is involved in the innate immune response to amyloid-β

(2008) Annett Halle et al.   NATURE IMMUNOLOGY