High Concentrations of Uric Acid and Angiotensin II Act Additively to Produce Endothelial Injury

Uric acid regulates NLRP3/IL-1β signaling pathway and further induces vascular endothelial cells injury in early CKD through ROS activation and K+ efflux

(2019) Wei Yin et al.   BMC Nephrology

NLRP3 inflammasome activation is involved in Ang II-induced kidney damage via mitochondrial dysfunction

(2016) Yi Wen et al.   Oncotarget

High Concentrations of Uric Acid Inhibit Angiogenesis via Regulation of the Krüppel-Like Factor 2-Vascular Endothelial Growth Factor-A Axis by miR-92a

(2015) Shandong Yu et al.   CIRCULATION JOURNAL

High Concentrations of Uric Acid Inhibit Endothelial Cell Migration via miR-663 Which Regulates Phosphatase and Tensin Homolog by Targeting Transforming Growth Factor-β1

(2015) Quan Hong et al.   MICROCIRCULATION

Smilacis Glabrae RhizomaReduces Oxidative Stress Caused by Hyperuricemia via Upregulation of Catalase

(2014) Quan Hong et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

ALDR Enhanced Endothelial Injury in Hyperuricemia Screened using SILAC

(2014) Yang Zhang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

ROS Function in Redox Signaling and Oxidative Stress

(2014) Michael Schieber et al.   CURRENT BIOLOGY

Angiotensin-converting-enzyme inhibition counteracts angiotensin II-mediated endothelial cell dysfunction by modulating the p38/SirT1 axis

(2013) Francesco Marampon et al.   JOURNAL OF HYPERTENSION

Hyperuricemia induces endothelial dysfunction via mitochondrial Na+/Ca2+ exchanger-mediated mitochondrial calcium overload

(2012) Quan Hong et al.   CELL CALCIUM

Is there anything good in uric acid?

(2011) B. Alvarez-Lario et al.   QJM-AN INTERNATIONAL JOURNAL OF MEDICINE

SnapShot: Reactive Oxygen Intermediates (ROI)

(2010) Carl Nathan et al.   CELL

Uric acid and evolution

(2010) B. Alvarez-Lario et al.   RHEUMATOLOGY

Relationship Between Serum Uric Acid Levels, Metabolic Syndrome, and Arterial Stiffness in Korean

(2010) Ji Hyon Lim et al.   Korean Circulation Journal

Hypothesis: Could Excessive Fructose Intake and Uric Acid Cause Type 2 Diabetes?

(2009) Richard J. Johnson et al.   ENDOCRINE REVIEWS

Elevated Uric Acid Increases the Risk for Kidney Disease

(2008) R. P. Obermayr et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Uric Acid and Cardiovascular Risk

(2008) Daniel I. Feig et al.   NEW ENGLAND JOURNAL OF MEDICINE

Inactivation of Nitric Oxide by Uric Acid

(2008) Christine Gersch et al.   NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS

Exercise-Induced Oxidative Stress: Cellular Mechanisms and Impact on Muscle Force Production

(2008) Scott K. Powers et al.   PHYSIOLOGICAL REVIEWS