Resveratrol attenuates manganese-induced oxidative stress and neuroinflammation through SIRT1 signaling in mice

The transcription factor REST up-regulates tyrosine hydroxylase and antiapoptotic genes and protects dopaminergic neurons against manganese toxicity

(2020) Edward Pajarillo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sinomenine inhibits amyloid beta-induced astrocyte activation and protects neurons against indirect toxicity

(2020) Deepali Singh et al.   Molecular Brain

Astrocyte and Oligodendrocyte Cross-Talk in the Central Nervous System

(2020) Erik Nutma et al.   Cells

ROS Generation in Microglia: Understanding Oxidative Stress and Inflammation in Neurodegenerative Disease

(2020) Dominic S. A. Simpson et al.   Antioxidants

Oxidative stress and inflammation in osteoarthritis pathogenesis: Role of polyphenols

(2020) Mohammad Yunus Ansari et al.   BIOMEDICINE & PHARMACOTHERAPY

Alpha-synuclein is involved in manganese-induced spatial memory and synaptic plasticity impairments via TrkB/Akt/Fyn-mediated phosphorylation of NMDA receptors

(2020) Zhuo Ma et al.   Cell Death & Disease

Metal Toxicity Links to Alzheimer’s Disease and Neuroinflammation

(2019) Tee Jong Huat et al.   JOURNAL OF MOLECULAR BIOLOGY

SIRT1 inhibits gastric cancer proliferation and metastasis via STAT3/MMP-13 signaling

(2019) Shu Zhang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Ethanol increases manganese—Induced spatial learning and memory deficits via oxidative/nitrosative stress induced p53 dependent/independent hippocampal apoptosis

(2019) Kpobari W. Nkpaa et al.   TOXICOLOGY

Influence of Resveratrol on the Immune Response

(2019) Malaguarnera   Nutrients

Caffeine Modulates Cadmium-Induced Oxidative Stress, Neuroinflammation, and Cognitive Impairments by Regulating Nrf-2/HO-1 In Vivo and In Vitro

(2019) Amjad Khan et al.   Journal of Clinical Medicine

A benchmark concentration analysis for manganese in drinking water and IQ deficits in children

(2019) Savroop S. Kullar et al.   ENVIRONMENT INTERNATIONAL

Manganese-Induced Neurotoxicity: New Insights Into the Triad of Protein Misfolding, Mitochondrial Impairment, and Neuroinflammation

(2019) Dilshan S. Harischandra et al.   Frontiers in Neuroscience

17β-Estradiol Modulates SIRT1 and Halts Oxidative Stress-Mediated Cognitive Impairment in a Male Aging Mouse Model

(2019) Mehtab Khan et al.   Cells

Dysregulation of TFEB contributes to manganese-induced autophagic failure and mitochondrial dysfunction in astrocytes

(2019) Ziyan Zhang et al.   Autophagy

Establishment of resveratrol and its derivatives as neuroprotectant against monocrotophos-induced alteration in NIPBL and POU4F1 protein through molecular docking studies

(2019) Ruchi Yadav et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Mitochondria regulation in ferroptosis

(2019) Hai Wang et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Neuroinflammation as a Factor of Neurodegenerative Disease: Thalidomide Analogs as Treatments

(2019) Yoo Jin Jung et al.   Frontiers in Cell and Developmental Biology

Resveratrol prevents cognitive deficits induced by chronic unpredictable mild stress: Sirt1/miR-134 signalling pathway regulates CREB/BDNF expression in hippocampus in vivo and in vitro

(2018) Jun Shen et al.   BEHAVIOURAL BRAIN RESEARCH

Effects of Resveratrol and other Polyphenols on Sirt1: Relevance to Brain Function During Aging

(2018) F. Sarubbo et al.   Current Neuropharmacology

Growth parameters at birth mediate the relationship between prenatal manganese exposure and cognitive test scores among a cohort of 2- to 3-year-old Bangladeshi children

(2018) Jane J Lee et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

SIRT1 Mediates Apelin-13 in Ameliorating Chronic Normobaric Hypoxia-induced Anxiety-like Behavior by Suppressing NF-κB Pathway in Mice Hippocampus

(2018) Junming Fan et al.   NEUROSCIENCE

Low level exposure to manganese from drinking water and cognition in school-age children

(2018) Maryse F. Bouchard et al.   NEUROTOXICOLOGY

Neuroinflammation in the central nervous system: Symphony of glial cells

(2018) Qiao‐qiao Yang et al.   GLIA

Resveratrol Protects Against Renal Damage via Attenuation of Inflammation and Oxidative Stress in High-Fat-Diet-Induced Obese Mice

(2018) Kang Cheng et al.   INFLAMMATION

SIRT1 activation by butein attenuates sepsis-induced brain injury in mice subjected to cecal ligation and puncture via alleviating inflammatory and oxidative stress

(2018) Yanrong Zhu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Polyphenolic Extract of Euphorbia supina Attenuates Manganese-Induced Neurotoxicity by Enhancing Antioxidant Activity through Regulation of ER Stress and ER Stress-Mediated Apoptosis

(2017) Entaz Bahar et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

NF-κB Signaling Activation Induced by Chloroquine Requires Autophagosome, p62 Protein, and c-Jun N-terminal Kinase (JNK) Signaling and Promotes Tumor Cell Resistance

(2017) Seungwon Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glial contributions to neurodegeneration in tauopathies

(2017) Cheryl E. G. Leyns et al.   Molecular Neurodegeneration

Resveratrol as a Natural Autophagy Regulator for Prevention and Treatment of Alzheimer’s Disease

(2017) et al.   Nutrients

Actein induces autophagy and apoptosis in human bladder cancer by potentiating ROS/JNK and inhibiting AKT pathways

(2017) Lu Ji et al.   Oncotarget

Tumor-promoting function of apoptotic caspases by an amplification loop involving ROS, macrophages and JNK in Drosophila

(2017) Ernesto Pérez et al.   eLife

Resokaempferol-mediated anti-inflammatory effects on activated macrophages via the inhibition of JAK2/STAT3, NF-κB and JNK/p38 MAPK signaling pathways

(2016) Qian Yu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Manganese Is Essential for Neuronal Health

(2015) Kyle J. Horning et al.   Annual Review of Nutrition

Sequential activation of microglia and astrocyte cytokine expression precedes increased iba-1 or GFAP immunoreactivity following systemic immune challenge

(2015) Diana M. Norden et al.   GLIA

Role of Transcription Factor Acetylation in Diabetic Kidney Disease

(2014) R. Liu et al.   DIABETES

Resveratrol attenuates 6-hydroxydopamine-induced oxidative damage and dopamine depletion in rat model of Parkinson's disease

(2010) Mohd.Moshahid Khan et al.   BRAIN RESEARCH