Recent Advances in Lipopolysaccharide-Based Glycoconjugate Vaccines

Chemical Synthesis and Immunological Evaluation of a Pentasaccharide Bearing Multiple Rare Sugars as a Potential Anti-pertussis Vaccine

(2020) Peng Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

LPS-binding IgG arrests actively motile Salmonella Typhimurium in gastrointestinal mucus

(2020) Holly A. Schroeder et al.   Mucosal Immunology

Automated Glycan Assembly in a Variable-Bed Flow Reactor Provides Insights into Oligosaccharide–Resin Interactions

(2020) Eric T. Sletten et al.   ORGANIC LETTERS

Elicitation of integrated immunity in mice by a novel pneumococcal polysaccharide vaccine conjugated with HBV surface antigen

(2020) Wen Qian et al.   Scientific Reports

Route of Vaccine Administration Alters Antigen Trafficking but Not Innate or Adaptive Immunity

(2020) Sebastian Ols et al.   Cell Reports

Biodegradable PLGA-b-PEG Nanoparticles Induce T Helper 2 (Th2) Immune Responses and Sustained Antibody Titers via TLR9 Stimulation

(2020) Kirsty L. Wilson et al.   Vaccines

Improving protein glycan coupling technology (PGCT) for glycoconjugate vaccine production

(2020) Jennifer Mhairi Dow et al.   Expert Review of Vaccines

Click chemistry compared to thiol chemistry for the synthesis of site-selective glycoconjugate vaccines using CRM197 as carrier protein

(2020) G. Stefanetti et al.   GLYCOCONJUGATE JOURNAL

Immunological effects of two new nanovaccines against Brucella based on OPS and LPS antigens conjugated with PLGA nanoparticles

(2020) Hossein Afshari et al.   EUROPEAN POLYMER JOURNAL

Multicomponent gold nano-glycoconjugate as a highly immunogenic and protective platform against Burkholderia mallei

(2020) Daniel Tapia et al.   npj Vaccines

Polyethylenimine-coated PLGA nanoparticles-encapsulated Angelica sinensis polysaccharide as an adjuvant for H9N2 vaccine to improve immune responses in chickens compared to Alum and oil-based adjuvants

(2020) Pengfei Gu et al.   VETERINARY MICROBIOLOGY

Safety and immunogenicity of a synthetic carbohydrate conjugate vaccine against Shigella flexneri 2a in healthy adult volunteers: a phase 1, dose-escalating, single-blind, randomised, placebo-controlled study

(2020) Dani Cohen et al.   LANCET INFECTIOUS DISEASES

A platform for glycoengineering a polyvalent pneumococcal bioconjugate vaccine using E. coli as a host

(2019) Christian M. Harding et al.   Nature Communications

Glycoconjugate vaccine using a genetically modified O antigen induces protective antibodies to Francisella tularensis

(2019) Giuseppe Stefanetti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IgM specific to lipopolysaccharide of Vibrio cholerae is a surrogate antibody isotype responsible for serum vibriocidal activity

(2019) Jae Seung Yang et al.   PLoS One

Automated Glycan Assembly: A Perspective

(2019) Mónica Guberman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Polymer-Coated Gold Nanospheres Do Not Impair the Innate Immune Function of Human B Lymphocytes in Vitro

(2019) Sandra Hočevar et al.   ACS Nano

Serum IgG antibodies to Shigella lipopolysaccharide antigens – a correlate of protection against shigellosis

(2019) Dani Cohen et al.   Human Vaccines & Immunotherapeutics

Recent advances in the production of recombinant glycoconjugate vaccines

(2019) Emily Kay et al.   npj Vaccines

Isolation, purification, characterization and direct conjugation of the lipid A‐free lipopolysaccharide of Vibrio cholerae O139

(2019) Peng Xu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Safety and immunogenicity of a vaccine for extra-intestinal pathogenic Escherichia coli (ESTELLA): a phase 2 randomised controlled trial

(2019) Robert W Frenck et al.   LANCET INFECTIOUS DISEASES

Classical and novel strategies to develop a Shigella glycoconjugate vaccine: from concept to efficacy in human

(2019) Louis-Antoine Barel et al.   Human Vaccines & Immunotherapeutics

Glycoconjugate vaccines: current approaches towards faster vaccine design

(2019) Francesca Micoli et al.   Expert Review of Vaccines

A promising bioconjugate vaccine against hypervirulent Klebsiella pneumoniae

(2019) Mario F. Feldman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Review of Newly Identified Functions Associated With the Heat-Labile Toxin of Enterotoxigenic Escherichia coli

(2019) Qiangde Duan et al.   Frontiers in Cellular and Infection Microbiology

Site-selective reactions for the synthesis of glycoconjugates in polysaccharide vaccine development

(2019) Lei Lin et al.   CARBOHYDRATE POLYMERS

Inhibition of Francisella tularensis phagocytosis using a novel anti-LPS scFv antibody fragment

(2019) Adva Mechaly et al.   Scientific Reports

Structural and immunological characterization of a glycoconjugate based on the delipidated lipopolysaccharide from a nontypeable Helicobacter pylori strain PJ1 containing an extended d - glycero - d - manno -heptan

(2018) Eleonora Altman et al.   CARBOHYDRATE RESEARCH

Protein Carriers for Glycoconjugate Vaccines: History, Selection Criteria, Characterization and New Trends

(2018) Francesca Micoli et al.   MOLECULES

Recent Advances in the Synthesis of Glycoconjugates for Vaccine Development

(2018) Cinzia Colombo et al.   MOLECULES

PLGA particulate subunit tuberculosis vaccines promote humoral and Th17 responses but do not enhance control of Mycobacterium tuberculosis infection

(2018) Anneliese S. Ashhurst et al.   PLoS One

Effect of Tdap upon antibody response to meningococcal polysaccharide when administered before, with or after the quadrivalent meningococcal TT-conjugate vaccine (coadministered with the 13-valent pneumococcal CRM197-conjugate vaccine) in adult Hajj pilgrims: A randomised controlled trial

(2018) M. Tashani et al.   VACCINE

Salmonella Typhi Bactericidal Antibodies Reduce Disease Severity but Do Not Protect against Typhoid Fever in a Controlled Human Infection Model

(2018) Helene B. Juel et al.   Frontiers in Immunology

Dendritic Cells in the Cross Hair for the Generation of Tailored Vaccines

(2018) Laura Gornati et al.   Frontiers in Immunology

Design and production of conjugate vaccines against S. Paratyphi A using an O-linked glycosylation system in vivo

(2018) Peng Sun et al.   npj Vaccines

Evaluation of a conjugate vaccine platform against enterotoxigenic Escherichia coli (ETEC), Campylobacter jejuni and Shigella

(2018) Renee M. Laird et al.   VACCINE

Polysaccharide structure dictates mechanism of adaptive immune response to glycoconjugate vaccines

(2018) Ximei Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

On the mechanisms of conjugate vaccines

(2018) Rino Rappuoli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Global, regional, and national estimates of pneumonia morbidity and mortality in children younger than 5 years between 2000 and 2015: a systematic analysis

(2018) David A McAllister et al.   Lancet Global Health

Oral Helicobacter pylori vaccine-encapsulated acid-resistant HP55/PLGA nanoparticles promote immune protection

(2017) Zhoulin Tan et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Recombinant Mip-PilE-FlaA dominant epitopes vaccine candidate against Legionella pneumophila

(2017) Jinlei He et al.   IMMUNOLOGY LETTERS

T Cell–Mediated Humoral Immune Responses to Type 3 Capsular Polysaccharide ofStreptococcus pneumoniae

(2017) Dustin R. Middleton et al.   JOURNAL OF IMMUNOLOGY

Automated glycan assembly using the Glyconeer 2.1 synthesizer

(2017) Heung Sik Hahm et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immunogenicity of a Glycoconjugate from Hydrazine-Detoxified Lipopolysaccharide of Vibrio cholerae O139

(2017) A. Fleischhackerová-Slimáková et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Immunogenicity, safety and reactogenicity of the pneumococcal non-typeable Haemophilus influenzae protein D conjugate vaccine (PHiD-CV) in 2–17-year-old children with asplenia or splenic dysfunction: A phase 3 study

(2017) L. Szenborn et al.   VACCINE

Vaccination with Shigella flexneri 2a conjugate induces type 2a and cross-reactive type 6 antibodies in humans but not in mice

(2017) Nahid Farzam et al.   VACCINE

Polysaccharide conjugate vaccine protein carriers as a “neglected valency” – Potential and limitations

(2017) Michael Bröker et al.   VACCINE

Deciphering minimal antigenic epitopes associated with Burkholderia pseudomallei and Burkholderia mallei lipopolysaccharide O-antigens

(2017) Marielle Tamigney Kenfack et al.   Nature Communications

Safety and Immunogenicity of a Candidate Bioconjugate Vaccine against Shigella flexneri 2a Administered to Healthy Adults: a Single-Blind, Randomized Phase I Study

(2016) Mark S. Riddle et al.   Clinical and Vaccine Immunology

The effect of preexisting anti-carrier immunity on subsequent responses to CRM197or Qb-VLP conjugate vaccines

(2016) Michael J. McCluskie et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Chemoenzymatic synthesis of the bacterial polysaccharide repeating unit undecaprenyl pyrophosphate and its analogs

(2016) Lei Li et al.   Nature Protocols

Vaccines for Antibiotic-Resistant Bacteria: Possibility or Pipe Dream?

(2016) Meritxell García-Quintanilla et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Carrier priming effect of CRM 197 is related to an enhanced B and T cell activation in meningococcal serogroup A conjugate vaccination. Immunological comparison between CRM 197 and diphtheria toxoid

(2016) S. Pecetta et al.   VACCINE

Biosynthesis of Conjugate Vaccines Using an O-Linked Glycosylation System

(2016) Chao Pan et al.   mBio

Recombinant expression ofStreptococcus pneumoniaecapsular polysaccharides inEscherichia coli

(2016) Emily J. Kay et al.   Open Biology

Sugar-Protein Connectivity Impacts on the Immunogenicity of Site-SelectiveSalmonellaO-Antigen Glycoconjugate Vaccines

(2015) Giuseppe Stefanetti et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Click Chemistry Applied to the Synthesis of Salmonella Typhimurium O-Antigen Glycoconjugate Vaccine on Solid Phase with Sugar Recycling

(2015) Giuseppe Stefanetti et al.   BIOCONJUGATE CHEMISTRY

Antigenic Potential of a Highly Conserved Neisseria meningitidis Lipopolysaccharide Inner Core Structure Defined by Chemical Synthesis

(2015) Anika Reinhardt et al.   CHEMISTRY & BIOLOGY

Shigella Outer Membrane Protein PSSP-1 Is Broadly Protective against Shigella Infection

(2015) Jae-Ouk Kim et al.   Clinical and Vaccine Immunology

Lipopolysaccharide (LPS) exposure differently affects allergic asthma exacerbations and its amelioration by intranasal curcumin in mice

(2015) Asha Kumari et al.   CYTOKINE

Monoclonal Antibodies of a Diverse Isotype Induced by an O-Antigen Glycoconjugate Vaccine MediateIn VitroandIn VivoKilling of African Invasive Nontyphoidal Salmonella

(2015) Yun Shan Goh et al.   INFECTION AND IMMUNITY

Phase 1 testing of detoxified LPS/group B meningococcal outer membrane protein vaccine with and without synthetic CPG 7909 adjuvant for the prevention and treatment of sepsis

(2015) Alan S. Cross et al.   VACCINE

Safety and immunogenicity of a candidate bioconjugate vaccine against Shigella dysenteriae type 1 administered to healthy adults: A single blind, partially randomized Phase I study

(2015) Christoph F.R Hatz et al.   VACCINE

Carrier priming with CRM197 or diphtheria toxoid has a different impact on the immunogenicity of the respective glycoconjugates: Biophysical and immunochemical interpretation

(2015) S. Pecetta et al.   VACCINE

Potential protective immunogenicity of tetanus toxoid, diphtheria toxoid and Cross Reacting Material 197 (CRM197) when used as carrier proteins in glycoconjugates

(2015) Michael Bröker   Human Vaccines & Immunotherapeutics

Interactions of conjugate vaccines and co-administered vaccines

(2015) H Findlow et al.   Human Vaccines & Immunotherapeutics

Increased efficiency of Campylobacter jejuni N-oligosaccharyltransferase PglB by structure-guided engineering

(2015) J. Ihssen et al.   Open Biology

A Cholera Conjugate Vaccine Containing O-specific Polysaccharide (OSP) of V. cholerae O1 Inaba and Recombinant Fragment of Tetanus Toxin Heavy Chain (OSP:rTTHc) Induces Serum, Memory and Lamina Proprial Responses against OSP and Is Protective in Mice

(2015) Md. Abu Sayeed et al.   PLoS Neglected Tropical Diseases

Production of Anti-LPS IgM by B1a B Cells Depends on IL-1β and Is Protective against Lung Infection with Francisella tularensis LVS

(2015) Laura del Barrio et al.   PLoS Pathogens

Recombinant Salmonella Expressing Burkholderia mallei LPS O Antigen Provides Protection in a Murine Model of Melioidosis and Glanders

(2015) Dina A. Moustafa et al.   PLoS One

Tyrosine-Directed Conjugation of Large Glycans to Proteins via Copper-Free Click Chemistry

(2014) Alberto Nilo et al.   BIOCONJUGATE CHEMISTRY

Chemistry of Lipid A: At the Heart of Innate Immunity

(2014) Antonio Molinaro et al.   CHEMISTRY-A EUROPEAN JOURNAL

Serum Bactericidal Assays To Evaluate Typhoidal and Nontyphoidal Salmonella Vaccines

(2014) Mary Adetinuke Boyd et al.   Clinical and Vaccine Immunology

Importance of (antibody-dependent) complement-mediated serum killing in protection againstBordetella pertussis

(2014) Jeroen Geurtsen et al.   Expert Review of Vaccines

Design of Glycoconjugate Vaccines against Invasive African Salmonella enterica Serovar Typhimurium

(2014) S. Rondini et al.   INFECTION AND IMMUNITY

Development of Yersinia pestis F1 antigen-loaded microspheres vaccine against plague

(2014) Ming-Kung Yeh et al.   International Journal of Nanomedicine

Dissecting the Contribution of IgG Subclasses in Restricting Airway Infection withLegionella pneumophila

(2014) Stefan S. Weber et al.   JOURNAL OF IMMUNOLOGY

Intradermal Delivery of Shigella IpaB and IpaD Type III Secretion Proteins: Kinetics of Cell Recruitment and Antigen Uptake, Mucosal and Systemic Immunity, and Protection across Serotypes

(2014) S. J. Heine et al.   JOURNAL OF IMMUNOLOGY

The Sweet Tooth of Bacteria: Common Themes in Bacterial Glycoconjugates

(2014) H. L. P. Tytgat et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Carrier priming or suppression: Understanding carrier priming enhancement of anti-polysaccharide antibody response to conjugate vaccines

(2014) Karl Pobre et al.   VACCINE

Impact of conjugation chemistry on the immunogenicity of S. Typhimurium conjugate vaccines

(2014) G. Stefanetti et al.   VACCINE

Structural modifications ofHelicobacter pylorilipopolysaccharide: An idea for how to live in peace

(2014) Magdalena Chmiela   WORLD JOURNAL OF GASTROENTEROLOGY

A universal polysaccharide conjugated vaccine against O111 E. coli

(2014) Gabrielle R Andrade et al.   Human Vaccines & Immunotherapeutics

Synthesis and immunogenicity evaluation of Salmonella enterica serovar Paratyphi A O-specific polysaccharide conjugated to diphtheria toxoid

(2014) Aamir Ali et al.   Human Vaccines & Immunotherapeutics

Evaluation in Mice of a Conjugate Vaccine for Cholera Made from Vibrio cholerae O1 (Ogawa) O-Specific Polysaccharide

(2014) Mohammad Murshid Alam et al.   PLoS Neglected Tropical Diseases

Production of a recombinant vaccine candidate against Burkholderia pseudomallei exploiting the bacterial N-glycosylation machinery

(2014) Fatima Garcia-Quintanilla et al.   Frontiers in Microbiology

Protection against Experimental Melioidosis following Immunisation with a Lipopolysaccharide-Protein Conjugate

(2014) Andrew E. Scott et al.   Journal of Immunology Research

Gold Nanoparticles as a Vaccine Platform: Influence of Size and Shape on Immunological Responses in Vitro and in Vivo

(2013) Kenichi Niikura et al.   ACS Nano

The effect of Haemophilus influenzae type B and pneumococcal conjugate vaccines on childhood meningitis mortality: a systematic review

(2013) Stephanie Davis et al.   BMC PUBLIC HEALTH

Role of Antilipopolysaccharide Antibodies in Serum Bactericidal Activity against Salmonella enterica Serovar Typhimurium in Healthy Adults and Children in the United States

(2013) Estela Trebicka et al.   Clinical and Vaccine Immunology

Chemoenzymatic synthesis of immunogenic meningococcal group C polysialic acid-tetanus Hc fragment glycoconjugates

(2013) Pumtiwitt C. McCarthy et al.   GLYCOCONJUGATE JOURNAL

The potential of dextran-based glycoconjugates for development of Helicobacter pylori vaccine

(2013) Eleonora Altman et al.   GLYCOCONJUGATE JOURNAL

Investigating the candidacy of LPS-based glycoconjugates to prevent invasive meningococcal disease: conjugates based on core oligosaccharides

(2013) F. St. Michael et al.   GLYCOCONJUGATE JOURNAL

Immunochemical characterization of synthetic hexa-, octa- and decasaccharide conjugate vaccines for Vibrio cholerae O:1 Serotype Ogawa with emphasis on antigenic density and chain length

(2013) Peter Ftacek et al.   GLYCOCONJUGATE JOURNAL

Invasive African Salmonella Typhimurium induces bactericidal antibodies against O-antigens

(2013) Simona Rondini et al.   MICROBIAL PATHOGENESIS

Protein carriers of conjugate vaccines: Characteristics, development and clinical trials

(2013) Michael E Pichichero   Human Vaccines & Immunotherapeutics

Exploitation of bacterial N-linked glycosylation to develop a novel recombinant glycoconjugate vaccine against Francisella tularensis

(2013) J. Cuccui et al.   Open Biology

Development of Burkholderia mallei and pseudomallei vaccines

(2013) Ediane B. Silva et al.   Frontiers in Cellular and Infection Microbiology

Acid-detoxified Inaba lipopolysaccharide (pmLPS) is a superior cholera conjugate vaccine immunogen than hydrazine-detoxified lipopolysaccharide and induces vibriocidal and protective antibodies

(2013) Cyrille Grandjean et al.   Pathogens and Disease

Lipopolysaccharide Inhibits Th2 Lung Inflammation Induced by House Dust Mite Allergens in Mice

(2012) J. Daan de Boer et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

A scalable method for O-antigen purification applied to various Salmonella serovars

(2012) F. Micoli et al.   ANALYTICAL BIOCHEMISTRY

Comparison of Immune Responses to the O-Specific Polysaccharide and Lipopolysaccharide of Vibrio cholerae O1 in Bangladeshi Adult Patients with Cholera

(2012) Russell A. Johnson et al.   Clinical and Vaccine Immunology

Live Oral Typhoid Vaccine Ty21a Induces Cross-Reactive Humoral Immune Responses against Salmonella enterica Serovar Paratyphi A andS. Paratyphi B in Humans

(2012) Rezwanul Wahid et al.   Clinical and Vaccine Immunology

Transcutaneous Immunization with a Vibrio cholerae O1 Ogawa Synthetic Hexasaccharide Conjugate following Oral Whole-Cell Cholera Vaccination Boosts Vibriocidal Responses and Induces Protective Immunity in Mice

(2012) A. A. Tarique et al.   Clinical and Vaccine Immunology

A century of pneumococcal vaccination research in humans

(2012) J.D. Grabenstein et al.   CLINICAL MICROBIOLOGY AND INFECTION

Evaluation of a LPS-based glycoconjugate vaccine against bovine Escherichia coli mastitis: Formation of LPS Abs in cows after immunization with E. coli core oligosaccharides conjugated to hemocyanine

(2012) Lore Brade et al.   Innate Immunity

Gold nanoparticles as carriers for a syntheticStreptococcus pneumoniaetype 14 conjugate vaccine

(2012) Dodi Safari et al.   Nanomedicine

Moraxella catarrhalis Activates Murine Macrophages through Multiple Toll Like Receptors and Has Reduced Clearance in Lungs from TLR4 Mutant Mice

(2012) Ferdaus Hassan et al.   PLoS One

O:2-CRM197 Conjugates against Salmonella Paratyphi A

(2012) Francesca Micoli et al.   PLoS One

Development of novel O-polysaccharide based glycoconjugates for immunization against glanders

(2012) Mary N. Burtnick et al.   Frontiers in Cellular and Infection Microbiology

Simple, Direct Conjugation of Bacterial O-SP–Core Antigens to Proteins: Development of Cholera Conjugate Vaccines

(2011) Peng Xu et al.   BIOCONJUGATE CHEMISTRY

Mucosal Immunologic Responses in Cholera Patients in Bangladesh

(2011) Taher Uddin et al.   Clinical and Vaccine Immunology

The design of semi-synthetic and synthetic glycoconjugate vaccines

(2011) Paolo Costantino et al.   Expert Opinion on Drug Discovery

Investigating the candidacy of lipopolysaccharide-based glycoconjugates as vaccines to combat Mannheimia haemolytica

(2011) Frank St. Michael et al.   GLYCOCONJUGATE JOURNAL

Investigating the potential of conserved inner core oligosaccharide regions of Moraxella catarrhalis lipopolysaccharide as vaccine antigens: accessibility and functional activity of monoclonal antibodies and glycoconjugate derived sera

(2011) Andrew D. Cox et al.   GLYCOCONJUGATE JOURNAL

The first use of an investigational multicomponent meningococcal serogroup B vaccine (4CMenB) in humans

(2011) Daniela Toneatto et al.   Human vaccines & immunotherapeutics

Importance of Antibodies to Lipopolysaccharide in Natural and Vaccine-Induced Serum Bactericidal Activity against Neisseria meningitidis Group B

(2011) Deborah H. Schmiel et al.   INFECTION AND IMMUNITY

Salmonella enterica Serovar Enteritidis Core O Polysaccharide Conjugated to H:g,m Flagellin as a Candidate Vaccine for Protection against Invasive Infection withS.Enteritidis

(2011) Raphael Simon et al.   INFECTION AND IMMUNITY

Anti-Pseudomonas aeruginosa serotype O11 LPS immunoglobulin M monoclonal antibody panobacumab (KBPA101) confers protection in a murine model of acute lung infection

(2011) T. Secher et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Synthesis of Laminarin Fragments and Evaluation of a β-(1,3) Glucan Hexasaccaride-CRM197Conjugate as Vaccine Candidate againstCandida albicans

(2011) Roberto Adamo et al.   JOURNAL OF CARBOHYDRATE CHEMISTRY

A mechanism for glycoconjugate vaccine activation of the adaptive immune system and its implications for vaccine design

(2011) Fikri Y Avci et al.   NATURE MEDICINE

Oligosaccharide conjugates of Bordetella pertussis and bronchiseptica induce bactericidal antibodies, an addition to pertussis vaccine

(2011) J. Kubler-Kielb et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of Francisella tularensis outer membrane protein A (FopA) as a protective antigen for tularemia

(2011) Anthony J. Hickey et al.   VACCINE

Cell-Associated Flagella Enhance the Protection Conferred by Mucosally-Administered Attenuated Salmonella Paratyphi A Vaccines

(2011) Orit Gat et al.   PLoS Neglected Tropical Diseases

Immunochemical studies of Shigella flexneri 2a and 6, and Shigella dysenteriae type 1 O-specific polysaccharide-core fragments and their protein conjugates as vaccine candidates

(2010) Joanna Kubler-Kielb et al.   CARBOHYDRATE RESEARCH

Antibody Response Patterns to Bordetella pertussis Antigens in Vaccinated (Primed) and Unvaccinated (Unprimed) Young Children with Pertussis

(2010) J. D. Cherry et al.   Clinical and Vaccine Immunology

Simultaneous vaccination with Prevenar and multicomponent vaccines for children: Interference or no interference?

(2010) Hein J. Boot et al.   Human vaccines & immunotherapeutics

Immunological efficacy of glycoconjugates derived from Vibrio cholerae O1 serotype Ogawa detoxified LPS in mice

(2010) E. Paulovicova et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Production of glycoprotein vaccines in Escherichia coli

(2010) Julian Ihssen et al.   Microbial Cell Factories

Age-related efficacy of Shigella O-specific polysaccharide conjugates in 1–4-year-old Israeli children

(2010) Justen H. Passwell et al.   VACCINE

Glycoconjugate vaccines and immune interference: A review

(2010) Ron Dagan et al.   VACCINE

The Bacterial Cell Envelope

(2010) T. J. Silhavy et al.   Cold Spring Harbor Perspectives in Biology

Antibody-mediated immunity to the obligate intracellular bacterial pathogen Coxiella burnetii is Fc receptor- and complement-independent

(2009) Jeffrey G Shannon et al.   BMC IMMUNOLOGY

Immunogenicity of a Heptavalent Conjugate Pneumococcal Vaccine Administered Concurrently with a Combination Diphtheria, Tetanus, Five-Component Acellular Pertussis, Inactivated Polio, and Haemophilus influenzae Type b Vaccine and a Meningococcal Group C Conjugate Vaccine at 2, 3, and 4 Months of Age

(2009) S. J. Moss et al.   Clinical and Vaccine Immunology

Enzymatic transglycosylation for glycoconjugate synthesis

(2009) Lai-Xi Wang et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

The structural basis of lipopolysaccharide recognition by the TLR4–MD-2 complex

(2009) Beom Seok Park et al.   NATURE

Synthesis, characterization, and immunogenicity in mice of Shigella sonnei O-specific oligosaccharide-core-protein conjugates

(2009) J. B. Robbins et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcutaneous immunization with a synthetic hexasaccharide-protein conjugate induces anti-Vibrio cholerae lipopolysaccharide responses in mice

(2009) Julianne E. Rollenhagen et al.   VACCINE

LPS/TLR4 signal transduction pathway

(2008) Yong-Chen Lu et al.   CYTOKINE

Combination vaccines containing DTPa–Hib: impact of IPV and coadministration of CRM197 conjugates

(2008) Ron Dagan et al.   Expert Review of Vaccines

O Antigen Protects Bordetella parapertussis from Complement

(2008) E. M. Goebel et al.   INFECTION AND IMMUNITY

Escherichia coli O157:H7 Colonization in Cattle following Systemic and Mucosal Immunization with Purified H7 Flagellin

(2008) T. N. McNeilly et al.   INFECTION AND IMMUNITY

Targeting subcapsular antigens for prevention of Klebsiella pneumoniae infections

(2008) Abigail Clements et al.   VACCINE

Optimising the use of conjugate vaccines to prevent disease caused by Haemophilus influenzae type b, Neisseria meningitidis and Streptococcus pneumoniae

(2008) Caroline L. Trotter et al.   VACCINE