Protein carriers of conjugate vaccines: Characteristics, development and clinical trials

The Magnitude of the Antibody and Memory B Cell Responses during Priming with a Protein-Polysaccharide Conjugate Vaccine in Human Infants Is Associated with the Persistence of Antibody and the Intensity of Booster Response

(2014) G. B. Rohner et al.   JOURNAL OF IMMUNOLOGY

Capsular Gene Sequences and Genotypes of "Serotype 6E" Streptococcus pneumoniae Isolates

(2013) K. S. Ko et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Effects of the 10-Valent Pneumococcal Nontypeable Haemophilus influenzae Protein D-Conjugate Vaccine on Nasopharyngeal Bacterial Colonization in Young Children: A Randomized Controlled Trial

(2012) M. R. van den Bergh et al.   CLINICAL INFECTIOUS DISEASES

Dose-specific efficacy of Haemophilus influenzae type b conjugate vaccines: a systematic review and meta-analysis of controlled clinical trials

(2012) U. K. GRIFFITHS et al.   EPIDEMIOLOGY AND INFECTION

Effectiveness of the ten-valent pneumococcal Haemophilus influenzae protein D conjugate vaccine (PHiD-CV10) against invasive pneumococcal disease: a cluster randomised trial

(2012) Arto A Palmu et al.   LANCET

Impact of 13-valent Pneumococcal Conjugate Vaccine on Pneumococcal Nasopharyngeal Carriage in Children With Acute Otitis Media

(2012) Robert Cohen et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Safety and Immunogenicity of a Quadrivalent Meningococcal Polysaccharide Diphtheria Toxoid Conjugate Vaccine in Infants and Toddlers

(2012) L. Miriam Pina et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Immunogenicity and Safety of a 13-Valent Pneumococcal Conjugate Vaccine in Healthy Infants and Toddlers Given With Routine Vaccines in India

(2012) Yeshwant K. Amdekar et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Pneumococcal Carriage and Invasive Disease in Children Before Introduction of the 13-valent Conjugate Vaccine

(2012) Dolly Sharma et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Three-year Antibody Persistence and Safety After a Single Dose of Combined Haemophilus influenzae Type b (Hib)–Neisseria meningitidis Serogroup C-tetanus Toxoid Conjugate Vaccine in Hib-primed Toddlers

(2012) Robert Booy et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

A randomized study to assess the immunogenicity, antibody persistence and safety of a tetravalent meningococcal serogroups A, C, W-135 and Y tetanus toxoid conjugate vaccine in children aged 2–10 years

(2012) Timo Vesikari et al.   Human Vaccines & Immunotherapeutics

The immunogenicity and safety of an investigational meningococcal serogroups A, C, W-135 and Y tetanus toxoid conjugate vaccine (ACWY-TT) compared with a licensed meningococcal tetravalent polysaccharide vaccine

(2012) Ghassan Dbaibo et al.   Human Vaccines & Immunotherapeutics

Kinetics of Immune Responses to Nasal Challenge With Meningococcal Polysaccharide One Year After Serogroup-C Glycoconjugate Vaccination

(2011) James B. Wing et al.   CLINICAL INFECTIOUS DISEASES

A Randomized Study Comparing Combined Pneumococcal Conjugate and Polysaccharide Vaccination Schedules in Adults

(2011) R. Lazarus et al.   CLINICAL INFECTIOUS DISEASES

Kinetics of the Antibody Response to Tetanus-Diphtheria-Acellular Pertussis Vaccine in Women of Childbearing Age and Postpartum Women

(2011) B. A. Halperin et al.   CLINICAL INFECTIOUS DISEASES

Next generation pneumococcal vaccines

(2011) Kristin L Moffitt et al.   CURRENT OPINION IN IMMUNOLOGY

Persistence of immune responses after a single dose of Novartis meningococcal serogroup A, C, W-135 and Y CRM-197 conjugate vaccine (Menveo®) or Menactra® among healthy adolescents

(2011) Christopher J. Gill et al.   Human vaccines & immunotherapeutics

Safety and immunogenicity of a tetravalent meningococcal serogroups A, C, W-135 and Y conjugate vaccine in adolescents and adults

(2011) Nancy Bermal et al.   Human vaccines & immunotherapeutics

Co-administration of a novelHaemophilus influenzaetype b andNeisseria meningitidisserogroups C and Y-tetanus toxoid conjugate vaccine does not interfere with the immune response to antigens contained in infant vaccines routinely used in the United States

(2011) Gary S. Marshall et al.   Human vaccines & immunotherapeutics

Shifting Genetic Structure of Invasive Serotype 19A Pneumococci in the United States

(2011) Bernard W. Beall et al.   JOURNAL OF INFECTIOUS DISEASES

Serotype replacement in disease after pneumococcal vaccination

(2011) Daniel M Weinberger et al.   LANCET

Effectiveness of Serogroup C Meningococcal Conjugate Vaccine

(2011) Philippe De Wals et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Immunogenicity of a Single Dose of Tetravalent Meningococcal Serogroups A, C, W-135, and Y Conjugate Vaccine Administered to 2- to 10-year-olds Is Noninferior to a Licensed-ACWY Polysaccharide Vaccine With an Acceptable Safety Profile

(2011) Ziad A. Memish et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Immunogenicity and Safety of an Investigational Quadrivalent Meningococcal ACWY Tetanus Toxoid Conjugate Vaccine in Healthy Adolescents and Young Adults 10 to 25 Years of Age

(2011) Roger Baxter et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Persistence of Serum Bactericidal Antibody One Year After a Booster Dose of Either a Glycoconjugate or a Plain Polysaccharide Vaccine Against Serogroup C Neisseria meningitidis Given to Adolescents Previously Immunized With a Glycoconjugate Vaccine

(2011) Philip C. S. de Whalley et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

A Randomized Trial to Assess Safety and Immunogenicity of Alternative Formulations of a Quadrivalent Meningococcal (A, C, Y, and W-135) Tetanus Protein Conjugate Vaccine in Toddlers

(2011) Jodie McVernon et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Antibody Persistence After a Primary Series of a New DTaP-IPV-Hep B-PRP-T Combined Vaccine or Separate DTaP-IPV//PRP-T and Hepatitis B Vaccines at 2, 4, and 6 Months of Age and the Effect of a Subsequent DTaP-IPV//PRP-T Booster Vaccination at 18 Months of Age in Healthy Argentinean Infants

(2011) Marcelo Tregnaghi et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Safety and Immunogenicity of a Novel Quadrivalent Meningococcal CRM-conjugate Vaccine Given Concomitantly With Routine Vaccinations in Infants

(2011) Nicola P. Klein et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Safety and Immunogenicity of a 13-valent Pneumococcal Conjugate Vaccine in Healthy Infants and Toddlers Given With Routine Pediatric Vaccinations in Canada

(2011) Otto G. Vanderkooi et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Induction of Immunologic Memory Following Primary Vaccination With the 10-valent Pneumococcal Nontypeable Haemophilus influenzae Protein D Conjugate Vaccine in Infants

(2011) Markus Knuf et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Tetravalent meningococcal serogroups A, C, W-135 and Y conjugate vaccine is well tolerated and immunogenic when co-administered with measles–mumps–rubella–varicella vaccine during the second year of life: An open, randomized controlled trial

(2011) Timo Vesikari et al.   VACCINE

Impact of the 10-valent pneumococcal non-typeable Haemophilus influenzae Protein D conjugate vaccine (PHiD-CV) on bacterial nasopharyngeal carriage

(2011) Roman Prymula et al.   VACCINE

Immunogenicity and safety of a 13-valent pneumococcal conjugate vaccine given with routine pediatric vaccines in Taiwan

(2011) Li-Min Huang et al.   VACCINE

Randomized Trial on the Safety, Tolerability, and Immunogenicity of MenACWY-CRM, an Investigational Quadrivalent Meningococcal Glycoconjugate Vaccine, Administered Concomitantly with a Combined Tetanus, Reduced Diphtheria, and Acellular Pertussis Vaccine in Adolescents and Young Adults

(2010) R. Gasparini et al.   Clinical and Vaccine Immunology

Safety and Immunogenicity of a 13-Valent Pneumococcal Conjugate Vaccine Compared to Those of a 7-Valent Pneumococcal Conjugate Vaccine Given as a Three-Dose Series with Routine Vaccines in Healthy Infants and Toddlers

(2010) S. Esposito et al.   Clinical and Vaccine Immunology

Antibody Persistence after Serogroup C Meningococcal Conjugate Immunization of United Kingdom Primary‐School Children in 1999–2000 and Response to a Booster: A Phase 4 Clinical Trial

(2010) K. P. Perrett et al.   CLINICAL INFECTIOUS DISEASES

Safety and immunogenicity of an investigational quadrivalent meningococcal CRM197 conjugate vaccine, MenACWY-CRM, compared with licensed vaccines in adults in Latin America

(2010) D. Stamboulian et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Immunogenicity and Reactogenicity of a 13-Valent-pneumococcal Conjugate Vaccine Administered at 2, 4, and 12 Months of Age

(2010) Matthew D. Snape et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Immunogenicity and Safety of an Investigational Combined Haemophilus influenzae Type B-Neisseria meningitidis Serogroups C and Y-Tetanus Toxoid Conjugate Vaccine

(2010) Terry Nolan et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Safety and Immunogenicity of a 13-Valent Pneumococcal Conjugate Vaccine

(2010) K. A. Bryant et al.   PEDIATRICS

Immunogenicity and Safety of 13-Valent Pneumococcal Conjugate Vaccine in Infants and Toddlers

(2010) S. H. Yeh et al.   PEDIATRICS

Safety and immunogenicity of one dose of MenACWY-CRM, an investigational quadrivalent meningococcal glycoconjugate vaccine, when administered to adolescents concomitantly or sequentially with Tdap and HPV vaccines

(2010) A. Arguedas et al.   VACCINE

Safety, tolerability, and immunologic noninferiority of a 13-valent pneumococcal conjugate vaccine compared to a 7-valent pneumococcal conjugate vaccine given with routine pediatric vaccinations in Germany

(2010) Dorothee M. Kieninger et al.   VACCINE

Kinetics of Antibody Persistence following Administration of a Combination Meningococcal Serogroup C and Haemophilus influenzae Type b Conjugate Vaccine in Healthy Infants in the United Kingdom Primed with a Monovalent Meningococcal Serogroup C Vaccine

(2009) R. Borrow et al.   Clinical and Vaccine Immunology

Quadrivalent Meningococcal Vaccination of Adults: Phase III Comparison of an Investigational Conjugate Vaccine, MenACWY-CRM, with the Licensed Vaccine, Menactra

(2009) K. S. Reisinger et al.   Clinical and Vaccine Immunology

Immunogenicity and Reactogenicity of Pneumococcal Polysaccharide and Conjugate Vaccines in Alaska Native Adults 55–70 Years of Age

(2009) Karen M. Miernyk et al.   CLINICAL INFECTIOUS DISEASES

Randomized Study of Early versus Late Immunization with Pneumococcal Conjugate Vaccine after Allogeneic Stem Cell Transplantation

(2009) Catherine Cordonnier et al.   CLINICAL INFECTIOUS DISEASES

Phase III Comparison of an Investigational Quadrivalent Meningococcal Conjugate Vaccine with the Licensed Meningococcal ACWY Conjugate Vaccine in Adolescents

(2009) Lisa A. Jackson et al.   CLINICAL INFECTIOUS DISEASES

Safety and immunogenicity of an investigational quadrivalent meningococcal conjugate vaccine after one or two doses given to infants and toddlers

(2009) S. A. Halperin et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Quantitative and Qualitative Anamnestic Immune Responses to Pneumococcal Conjugate Vaccine in HIV‐Infected and HIV‐Uninfected Children 5 Years after Vaccination

(2009) Shabir A. Madhi et al.   JOURNAL OF INFECTIOUS DISEASES

Immunogenicity and Immune Memory of a Nonadjuvanted Quadrivalent Meningococcal Glycoconjugate Vaccine in Infants

(2009) Kirsten P. Perrett et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

The Impact of Childhood Meningococcal Serogroup C Conjugate Vaccine Programs in Canada

(2009) Julie A. Bettinger et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Nasopharyngeal Carriage of Streptococcus pneumoniae in Gambian Children who Participated in a 9-valent Pneumococcal Conjugate Vaccine Trial and in Their Younger Siblings

(2009) Yin-Bun Cheung et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

A Randomized Trial to Determine the Tolerability and Immunogenicity of a Quadrivalent Meningococcal Glycoconjugate Vaccine in Healthy Adolescents

(2009) Lisa A. Jackson et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Immunogenicity of a 2-Dose Priming and Booster Vaccination With the 10-Valent Pneumococcal Nontypeable Haemophilus influenzae Protein D Conjugate Vaccine

(2009) Sven Arne Silfverdal et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Immunogenicity of Routinely Used Childhood Vaccines When Coadministered With the 10-Valent Pneumococcal Non-typeable Haemophilus influenzae Protein D Conjugate Vaccine (PHiD-CV)

(2009) Markus Knuf et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Immunogenicity of the 10-Valent Pneumococcal Non-typeable Haemophilus influenzae Protein D Conjugate Vaccine (PHiD-CV) Compared to the Licensed 7vCRM Vaccine

(2009) Timo Vesikari et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Continued Impact of Pneumococcal Conjugate Vaccine on Carriage in Young Children

(2009) S. S. Huang et al.   PEDIATRICS

Booster Vaccinations: Can Immunologic Memory Outpace Disease Pathogenesis?

(2009) M. E. Pichichero   PEDIATRICS

A dose-range study assessing immunogenicity and safety of one dose of a new candidate meningococcal serogroups A, C, W-135, Y tetanus toxoid conjugate (MenACWY-TT) vaccine administered in the second year of life and in young children

(2009) M. Knuf et al.   VACCINE

Immunogenicity and tolerability of a quadrivalent meningococcal glycoconjugate vaccine in children 2–10 years of age

(2009) S. Black et al.   VACCINE

Indirect Effect of 7‐Valent Pneumococcal Conjugate Vaccine on Pneumococcal Colonization among Unvaccinated Household Members

(2008) Eugene V. Millar et al.   CLINICAL INFECTIOUS DISEASES

Vaccines: Correlates of Vaccine‐Induced Immunity

(2008) Stanley A. Plotkin   CLINICAL INFECTIOUS DISEASES

Immunogenicity of a Tetravalent Meningococcal Glycoconjugate Vaccine in Infants

(2008) Matthew D. Snape et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Initial and Subsequent Response to Pneumococcal Polysaccharide and Protein‐Conjugate Vaccines Administered Sequentially to Adults Who Have Recovered from Pneumococcal Pneumonia

(2008) Daniel M. Musher et al.   JOURNAL OF INFECTIOUS DISEASES

Impact of Meningococcal Serogroup C Conjugate Vaccines on Carriage and Herd Immunity

(2008) Martin C. J. Maiden et al.   JOURNAL OF INFECTIOUS DISEASES

TRENDS IN NASOPHARYNGEAL CARRIAGE OF STREPTOCOCCUS PNEUMONIAE AMONG CHILDREN ATTENDING DAYCARE CENTERS IN SOUTHEASTERN FRANCE FROM 1999 TO 2006

(2008) Brigitte Dunais et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Safety of the 11-valent pneumococcal vaccine conjugated to non-typeable Haemophilus influenzae-derived protein D in the first 2 years of life and immunogenicity of the co-administered hexavalent diphtheria, tetanus, acellular pertussis, hepatitis B, inactivated polio virus, Haemophilus influenzae type b and control hepatitis A vaccines

(2008) Roman Prymula et al.   VACCINE

Immunogenicity, reactogenicity and persistence of meningococcal A, C, W-135 and Y-tetanus toxoid candidate conjugate (MenACWY-TT) vaccine formulations in adolescents aged 15–25 years

(2008) Lars Østergaard et al.   VACCINE

Haemophilus influenzae Type b Vaccine Failure in Children Is Associated with Inadequate Production of High-Quality Antibody

(2007) Y. C. Lee et al.   CLINICAL INFECTIOUS DISEASES