Nicotinamide phosphoribosyltransferase (Nampt) in carcinogenesis: new clinical opportunities
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Nicotinamide phosphoribosyltransferase (Nampt) in carcinogenesis: new clinical opportunities
Authors
Keywords
-
Journal
Expert Review of Anticancer Therapy
Volume 16, Issue 8, Pages 827-838
Publisher
Informa UK Limited
Online
2016-05-18
DOI
10.1080/14737140.2016.1190649
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- FK866-induced NAMPT inhibition activates AMPK and downregulates mTOR signaling in hepatocarcinoma cells
- (2015) Susanne Schuster et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Dedifferentiation of cancer cells following recovery from a potentially lethal damage is mediated by H2S–Nampt
- (2015) Elena A. Ostrakhovitch et al. EXPERIMENTAL CELL RESEARCH
- Deciphering the BRCA1 Tumor Suppressor Network
- (2015) Qinqin Jiang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Generation, Release, and Uptake of the NAD Precursor Nicotinic Acid Riboside by Human Cells
- (2015) Veronika Kulikova et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Deacetylation of Nuclear LC3 Drives Autophagy Initiation under Starvation
- (2015) Rui Huang et al. MOLECULAR CELL
- NAMPT inhibition sensitizes pancreatic adenocarcinoma cells to tumor-selective, PAR-independent metabolic catastrophe and cell death induced by β-lapachone
- (2015) Z Moore et al. Cell Death & Disease
- Dependence of Tumor Cell Lines and Patient-Derived Tumors on the NAD Salvage Pathway Renders Them Sensitive to NAMPT Inhibition with GNE-618
- (2015) Yang Xiao et al. NEOPLASIA
- Derivatization of the tricarboxylic acid intermediates with O-benzylhydroxylamine for liquid chromatography–tandem mass spectrometry detection
- (2014) Bo Tan et al. ANALYTICAL BIOCHEMISTRY
- Extracellular nicotinamide phosphoribosyltransferase (NAMPT) promotes M2 macrophage polarization in chronic lymphocytic leukemia
- (2014) Valentina Audrito et al. BLOOD
- Synergy between the NAMPT Inhibitor GMX1777(8) and Pemetrexed in Non-Small Cell Lung Cancer Cells Is Mediated by PARP Activation and Enhanced NAD Consumption
- (2014) M. Chan et al. CANCER RESEARCH
- BRCA1 as a nicotinamide adenine dinucleotide (NAD)-dependent metabolic switch in ovarian cancer
- (2014) Da Li et al. CELL CYCLE
- A novel crosstalk between BRCA1 and poly (ADP-ribose) polymerase 1 in breast cancer
- (2014) Da Li et al. CELL CYCLE
- Structural and Biochemical Analyses of the Catalysis and Potency Impact of Inhibitor Phosphoribosylation by Human Nicotinamide Phosphoribosyltransferase
- (2014) Angela Oh et al. CHEMBIOCHEM
- On-Target Effect of FK866, a Nicotinamide Phosphoribosyl Transferase Inhibitor, by Apoptosis-Mediated Death in Chronic Lymphocytic Leukemia Cells
- (2014) I. Gehrke et al. CLINICAL CANCER RESEARCH
- Prognostic value of serum nicotinamide phosphoribosyltransferase in patients with bladder cancer
- (2014) Kui Zhang et al. CROATIAN MEDICAL JOURNAL
- Nicotinamide phosphoribosyltransferase can affect metastatic activity and cell adhesive functions by regulating integrins in breast cancer
- (2014) Antonio F. Santidrian et al. DNA REPAIR
- Blockade of visfatin induction by oleanolic acid via disturbing IL-6-TRAF6-NF-κB signaling of adipocytes
- (2014) Hyun-Sung Kim et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- Nicotinamide Phosphoribosyltransferase Promotes Epithelial-to-Mesenchymal Transition as a Soluble Factor Independent of Its Enzymatic Activity
- (2014) Debora Soncini et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A H2S-Nampt Dependent Energetic Circuit Is Critical to Survival and Cytoprotection from Damage in Cancer Cells
- (2014) Reiko Sanokawa-Akakura et al. PLoS One
- Metabolomics Analysis of Metabolic Effects of Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibition on Human Cancer Cells
- (2014) Vladimir Tolstikov et al. PLoS One
- Structural Basis for Resistance to Diverse Classes of NAMPT Inhibitors
- (2014) Weiru Wang et al. PLoS One
- NAD+ and sirtuins in aging and disease
- (2014) Shin-ichiro Imai et al. TRENDS IN CELL BIOLOGY
- Expression of Nicotinamide Phosphoribosyltransferase-Influenced Genes Predicts Recurrence-Free Survival in Lung and Breast Cancers
- (2014) Tong Zhou et al. Scientific Reports
- Low-grade inflammation in overweight and obese adults is affected by weight loss program
- (2014) Ana Petelin et al. JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
- Visfatin is involved in TNFα-mediated insulin resistance via an NAD+/Sirt1/PTP1B pathway in 3T3-L1 adipocytes
- (2014) Erwan Gouranton et al. Adipocyte
- Intracellular NAD+ depletion enhances bortezomib-induced anti-myeloma activity
- (2013) A. Cagnetta et al. BLOOD
- Hormones of adipose tissue and their biologic role in lung cancer
- (2013) E. Ntikoudi et al. CANCER TREATMENT REVIEWS
- Intracellular NAD(H) levels control motility and invasion of glioma cells
- (2013) Remco van Horssen et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Antagonistic crosstalk between NF-κB and SIRT1 in the regulation of inflammation and metabolic disorders
- (2013) Anu Kauppinen et al. CELLULAR SIGNALLING
- Loss of NAPRT1 Expression by Tumor-Specific Promoter Methylation Provides a Novel Predictive Biomarker for NAMPT Inhibitors
- (2013) D. S. Shames et al. CLINICAL CANCER RESEARCH
- Targeting of NAD Metabolism in Pancreatic Cancer Cells: Potential Novel Therapy for Pancreatic Tumors
- (2013) C. C. S. Chini et al. CLINICAL CANCER RESEARCH
- CD73 Protein as a Source of Extracellular Precursors for Sustained NAD+Biosynthesis in FK866-treated Tumor Cells
- (2013) Alessia Grozio et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Follicular Lymphoma Cells Induce Changes in T-Cell Gene Expression and Function: Potential Impact on Survival and Risk of Transformation
- (2013) Shahryar Kiaii et al. JOURNAL OF CLINICAL ONCOLOGY
- Structure-Based Discovery of Novel Amide-Containing Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors
- (2013) Xiaozhang Zheng et al. JOURNAL OF MEDICINAL CHEMISTRY
- Nicotinamide Phosphoribosyltransferase Inhibitors, Design, Preparation, and Structure–Activity Relationship
- (2013) Mette K. Christensen et al. JOURNAL OF MEDICINAL CHEMISTRY
- Medicinal Chemistry of Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors
- (2013) Ubaldina Galli et al. JOURNAL OF MEDICINAL CHEMISTRY
- Sweet Potato [Ipomoea batatas (L.) Lam. ^|^ldquo;Tainong 57^|^rdquo;] Starch Improves Insulin Sensitivity in High-Fructose Diet-Fed Rats by Ameliorating Adipocytokine Levels, Pro-Inflammatory Status, and Insulin Signaling
- (2013) Ya-Yen CHEN et al. JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY
- Visfatin/Nampt: An Adipokine with Cardiovascular Impact
- (2013) Tania Romacho et al. MEDIATORS OF INFLAMMATION
- [18F]FLT and [18F]FDG PET for Non-invasive Treatment Monitoring of the Nicotinamide Phosphoribosyltransferase Inhibitor APO866 in Human Xenografts
- (2013) Mette Munk Jensen et al. PLoS One
- The Evolutionary Portrait of Metazoan NAD Salvage
- (2013) João Carneiro et al. PLoS One
- Visfatin as a Novel Mediator Released by Inflamed Human Endothelial Cells
- (2013) Tania Romacho et al. PLoS One
- Genetic variants in NAMPT predict bladder cancer risk and prognosis in individuals from southwest Chinese Han group
- (2013) Kui Zhang et al. TUMOR BIOLOGY
- Clinical Implications of Adipocytokines and Newly Emerging Metabolic Factors with Relation to Insulin Resistance and Cardiovascular Health
- (2013) Sung Hee Choi et al. Frontiers in Endocrinology
- Visfatin/NAMPT: A Multifaceted Molecule with Diverse Roles in Physiology and Pathophysiology
- (2012) Tuva B. Dahl et al. Annual Review of Nutrition
- Guidelines for the use and interpretation of assays for monitoring autophagy
- (2012) Daniel J. Klionsky et al. Autophagy
- Inhibition of NAMPT pathway by FK866 activates the function of p53 in HEK293T cells
- (2012) Basant Kumar Thakur et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- NAMPT pathway is involved in the FOXO3a-mediated regulation of GADD45A expression
- (2012) Basant Kumar Thakur et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Targeting NAD+ salvage pathway induces autophagy in multiple myeloma cells via mTORC1 and extracellular signal-regulated kinase (ERK1/2) inhibition
- (2012) M. Cea et al. BLOOD
- Adipose Tissue as Regulator of Vascular Tone
- (2012) Charlotte Boydens et al. CURRENT HYPERTENSION REPORTS
- Synthetic lethality of PARP and NAMPT inhibition in triple-negative breast cancer cells
- (2012) Ilirjana Bajrami et al. EMBO Molecular Medicine
- Insulin Resistance and Cancer Risk: An Overview of the Pathogenetic Mechanisms
- (2012) Biagio Arcidiacono et al. Experimental Diabetes Research
- PBEF/NAMPT/visfatin: a promising drug target for treating rheumatoid arthritis?
- (2012) Mari Nowell et al. Future Medicinal Chemistry
- Involvement of p53 in the cytotoxic activity of the NAMPT inhibitor FK866 in myeloid leukemic cells
- (2012) Basant Kumar Thakur et al. INTERNATIONAL JOURNAL OF CANCER
- Relation of chemokines to BMI and insulin resistance at ages 18–21
- (2012) S Ognjanovic et al. INTERNATIONAL JOURNAL OF OBESITY
- Inhibition of Nicotinamide Phosphoribosyltransferase (NAMPT) Activity by Small Molecule GMX1778 Regulates Reactive Oxygen Species (ROS)-mediated Cytotoxicity in a p53- and Nicotinic Acid Phosphoribosyltransferase1 (NAPRT1)-dependent Manner
- (2012) David Cerna et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Pharmacological Inhibition of Nicotinamide Phosphoribosyltransferase (NAMPT), an Enzyme Essential for NAD+Biosynthesis, in Human Cancer Cells
- (2012) Bo Tan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Visfatin/Pre-B-cell Colony-enhancing Factor (PBEF), a Proinflammatory and Cell Motility-changing Factor in Rheumatoid Arthritis
- (2012) Florian M. P. Meier et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Carboranes Increase the Potency of Small Molecule Inhibitors of Nicotinamide Phosphoribosyltranferase
- (2012) Mark W. Lee et al. JOURNAL OF MEDICINAL CHEMISTRY
- Nicotinamide phosphoribosyl-transferase/visfatin: A missing link between overweight/obesity and postmenopausal breast cancer? Potential preventive and therapeutic perspectives and challenges
- (2012) Maria Dalamaga MEDICAL HYPOTHESES
- Nicotinamide phosphoribosyltransferase (NAMPT) is over-expressed in melanoma lesions
- (2012) Elena Maldi et al. Pigment Cell & Melanoma Research
- Nampt is involved in DNA double-strand break repair
- (2012) Bingtao Zhu et al. Chinese Journal of Cancer
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- NAMPT in Regulated NAD Biosynthesis and its Pivotal Role in Human Metabolism
- (2011) E S. Burgos CURRENT MEDICINAL CHEMISTRY
- The level of serum visfatin (PBEF) is associated with total number of B cells in patients with rheumatoid arthritis and decreases following B cell depletion therapy
- (2011) Ladislav Šenolt et al. CYTOKINE
- Leucocytes are a major source of circulating nicotinamide phosphoribosyltransferase (NAMPT)/pre-B cell colony (PBEF)/visfatin linking obesity and inflammation in humans
- (2011) D. Friebe et al. DIABETOLOGIA
- A combination of the metabolic enzyme inhibitor APO866 and the immune adjuvant L-1-methyl tryptophan induces additive antitumor activity
- (2011) Huei-Jiun Yang et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- Hepatic FoxOs Regulate Lipid Metabolism via Modulation of Expression of the Nicotinamide Phosphoribosyltransferase Gene
- (2011) Rongya Tao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Nicotinamide Phosphoribosyltransferase Is Essential for Interleukin-1β-mediated Dedifferentiation of Articular Chondrocytes via SIRT1 and Extracellular Signal-regulated Kinase (ERK) Complex Signaling
- (2011) Eun-Hee Hong et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The c-MYC oncoprotein, the NAMPT enzyme, the SIRT1-inhibitor DBC1, and the SIRT1 deacetylase form a positive feedback loop
- (2011) A. Menssen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Nampt/PBEF/visfatin and cancer
- (2010) Tie-qiang Bi et al. CANCER BIOLOGY & THERAPY
- Pre-B Cell Colony Enhancing Factor/NAMPT/Visfatin in Inflammation and Obesity- Related Disorders
- (2010) Alexander R. Moschen et al. CURRENT PHARMACEUTICAL DESIGN
- Diabetes and Cancer: A consensus report
- (2010) E. Giovannucci et al. DIABETES CARE
- Potent synergistic interaction between the Nampt inhibitor APO866 and the apoptosis activator TRAIL in human leukemia cells
- (2010) Gabriele Zoppoli et al. EXPERIMENTAL HEMATOLOGY
- NAMPT overexpression in prostate cancer and its contribution to tumor cell survival and stress response
- (2010) B Wang et al. ONCOGENE
- Nicotinamide phosphoribosyltransferase regulates cell survival through autophagy in cardiomyocytes
- (2009) Chiao-Po Hsu et al. Autophagy
- Nicotinamide phosphoribosyltransferase (NAMPT/PBEF/visfatin) is constitutively released from human hepatocytes
- (2009) A. Garten et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- SIRT1-dependent regulation of chromatin and transcription: Linking NAD+ metabolism and signaling to the control of cellular functions
- (2009) Tong Zhang et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Role of fat mass and adipokines in chronic kidney disease
- (2009) Jonas Axelsson et al. CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION
- Extracellular PBEF/NAMPT/visfatin activates pro-inflammatory signalling in human vascular smooth muscle cells through nicotinamide phosphoribosyltransferase activity
- (2009) T. Romacho et al. DIABETOLOGIA
- Structure and reaction mechanism of human nicotinamide phosphoribosyltransferase
- (2009) Ryo Takahashi et al. JOURNAL OF BIOCHEMISTRY
- Enzymes in the NAD+Salvage Pathway Regulate SIRT1 Activity at Target Gene Promoters
- (2009) Tong Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Crucial role of visfatin/pre–B cell colony-enhancing factor in matrix degradation and prostaglandin E2 synthesis in chondrocytes: Possible influence on osteoarthritis
- (2008) Marjolaine Gosset et al. ARTHRITIS AND RHEUMATISM
- Pre-B cell colony enhancing factor (PBEF)/visfatin induces secretion of MCP-1 in human endothelial cells: Role in visfatin-induced angiogenesis
- (2008) Raghu Adya et al. ATHEROSCLEROSIS
- Perivascular adipose tissue-derived visfatin is a vascular smooth muscle cell growth factor: role of nicotinamide mononucleotide
- (2008) Pei Wang et al. CARDIOVASCULAR RESEARCH
- Role of adiponectin and PBEF/visfatin as regulators of inflammation: involvement in obesity-associated diseases
- (2008) Herbert Tilg et al. CLINICAL SCIENCE
- Nampt: linking NAD biology, metabolism and cancer
- (2008) Antje Garten et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search