The c-MYC oncoprotein, the NAMPT enzyme, the SIRT1-inhibitor DBC1, and the SIRT1 deacetylase form a positive feedback loop
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Title
The c-MYC oncoprotein, the NAMPT enzyme, the SIRT1-inhibitor DBC1, and the SIRT1 deacetylase form a positive feedback loop
Authors
Keywords
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Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 109, Issue 4, Pages E187-E196
Publisher
Proceedings of the National Academy of Sciences
Online
2011-12-22
DOI
10.1073/pnas.1105304109
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Note: Only part of the references are listed.- Target enzyme mutations are the molecular basis for resistance towards pharmacological inhibition of nicotinamide phosphoribosyltransferase
- (2011) Uffe H Olesen et al. BMC CANCER
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- (2011) H P Mohammad et al. ONCOGENE
- Mammalian Sirtuins: Biological Insights and Disease Relevance
- (2010) Marcia C. Haigis et al. Annual Review of Pathology-Mechanisms of Disease
- Interactions between DBC1 and SIRT1 are deregulated in breast cancer cells
- (2010) Ja-Eun Kim et al. CELL CYCLE
- HDAC3 Is Negatively Regulated by the Nuclear Protein DBC1
- (2010) Claudia C. S. Chini et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2010) Jose A. Palacios et al. JOURNAL OF CELL BIOLOGY
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- (2010) Carlos Escande et al. JOURNAL OF CLINICAL INVESTIGATION
- Identification of a co-activator that links growth factor signalling to c-Jun/AP-1 activation
- (2010) Clare C. Davies et al. NATURE CELL BIOLOGY
- Transcriptional regulation of BRCA1 expression by a metabolic switch
- (2010) Li-Jun Di et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- NAMPT overexpression in prostate cancer and its contribution to tumor cell survival and stress response
- (2010) B Wang et al. ONCOGENE
- SIRT1-dependent regulation of chromatin and transcription: Linking NAD+ metabolism and signaling to the control of cellular functions
- (2009) Tong Zhang et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- The Critical Role of the Class III Histone Deacetylase SIRT1 in Cancer
- (2009) T. Liu et al. CANCER RESEARCH
- Nicotinamide Phosphoribosyltransferase (Nampt): A Link Between NAD Biology, Metabolism, and Diseases
- (2009) Shin-ichiro Imai CURRENT PHARMACEUTICAL DESIGN
- SIRT1 markedly extends replicative lifespan if the NAD+salvage pathway is enhanced
- (2009) Cynthia Ho et al. FEBS LETTERS
- Inhibition of SUV39H1 Methyltransferase Activity by DBC1
- (2009) Zhenyu Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A c-Myc–SIRT1 feedback loop regulates cell growth and transformation
- (2009) Jian Yuan et al. JOURNAL OF CELL BIOLOGY
- SIRT1 Promotes Cell Survival under Stress by Deacetylation-Dependent Deactivation of Poly(ADP-Ribose) Polymerase 1
- (2009) S. B. Rajamohan et al. MOLECULAR AND CELLULAR BIOLOGY
- Cdk2 suppresses cellular senescence induced by the c-myc oncogene
- (2009) Stefano Campaner et al. NATURE CELL BIOLOGY
- Phosphorylation by Cdk2 is required for Myc to repress Ras-induced senescence in cotransformation
- (2009) P. Hydbring et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Discovery, In Vivo Activity, and Mechanism of Action of a Small-Molecule p53 Activator
- (2008) Sonia Lain et al. CANCER CELL
- Myc's broad reach
- (2008) M. Eilers et al. GENES & DEVELOPMENT
- Negative regulation of the deacetylase SIRT1 by DBC1
- (2008) Wenhui Zhao et al. NATURE
- DBC1 is a negative regulator of SIRT1
- (2008) Ja-Eun Kim et al. NATURE
- Modelling Myc inhibition as a cancer therapy
- (2008) Laura Soucek et al. NATURE
- SIRT1 Overexpression Antagonizes Cellular Senescence with Activated ERK/S6k1 Signaling in Human Diploid Fibroblasts
- (2008) Jing Huang et al. PLoS One
- AP4 encodes a c-MYC-inducible repressor of p21
- (2008) P. Jung et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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