BRCA1 as a nicotinamide adenine dinucleotide (NAD)-dependent metabolic switch in ovarian cancer

Poly (ADP-ribose) polymerase 1 transcriptional regulation: A novel crosstalk between histone modification H3K9ac and ETS1 motif hypomethylation in BRCA1-mutated ovarian cancer

(2015) Da Li et al.   Oncotarget

Epigenetic repression of phosphatidylethanolamine N-methyltransferase (PEMT) in BRCA1-mutated breast cancer

(2015) Da Li et al.   Oncotarget

The NAD+synthesizing enzyme nicotinamide mononucleotide adenylyltransferase 2 (NMNAT-2) is a p53 downstream target

(2014) Lu-Zhe Pan et al.   CELL CYCLE

Development of Pyrazolone and Isoxazol-5-one Cambinol Analogues as Sirtuin Inhibitors

(2014) Sumit S. Mahajan et al.   JOURNAL OF MEDICINAL CHEMISTRY

Regulation of DNA methyltransferase 1 transcription in BRCA1-mutated breast cancer: a novel crosstalk between E2F1 motif hypermethylation and loss of histone H3 lysine 9 acetylation

(2014) Da Li et al.   Molecular Cancer

Depletion of Sirtuin 1 (SIRT1) Leads to Epigenetic Modifications of Telomerase (TERT) Gene in Hepatocellular Carcinoma Cells

(2014) Bin Zhang et al.   PLoS One

SIRT1 and other sirtuins in metabolism

(2014) Hung-Chun Chang et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Loss of glucocorticoid receptor activation is a hallmark of BRCA1-mutated breast tissue

(2013) Myriam Vilasco et al.   BREAST CANCER RESEARCH AND TREATMENT

Ovarian cancer as a genetic disease 

(2013) Anna Czarnecka   Frontiers in Bioscience-Landmark

Effect of BRCA1 on epidermal growth factor receptor in ovarian cancer

(2013) Da Li et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

BRCA1-Dependent Translational Regulation in Breast Cancer Cells

(2013) Estelle Dacheux et al.   PLoS One

When is Sirt1 activity bad for dying neurons?

(2013) Fanny Ng et al.   Frontiers in Cellular Neuroscience

Regulation of angiotensin II type 1 receptor expression in ovarian cancer: a potential role for BRCA1

(2013) Fang-Fang Bi et al.   Journal of Ovarian Research

IGF-1 and BRCA1 signalling pathways in familial cancer

(2012) Haim Werner et al.   LANCET ONCOLOGY

BRCA1 negatively regulates IGF-1 expression through an estrogen-responsive element-like site

(2012) H J Kang et al.   Cell Death & Disease

Multifunctional transcription factor TFII-I is an activator of BRCA1 function

(2011) M Tanikawa et al.   BRITISH JOURNAL OF CANCER

Energy Restriction during Childhood and Early Adulthood and Ovarian Cancer Risk

(2011) Leo J. Schouten et al.   PLoS One

Identification of DBC1 as a transcriptional repressor for BRCA1

(2010) H Hiraike et al.   BRITISH JOURNAL OF CANCER

Identification and Management of Women With BRCA Mutations or Hereditary Predisposition for Breast and Ovarian Cancer

(2010) Sandhya Pruthi et al.   MAYO CLINIC PROCEEDINGS

Transcriptional regulation of BRCA1 expression by a metabolic switch

(2010) Li-Jun Di et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Redox-dependent Brca1 transcriptional regulation by an NADH-sensor CtBP1

(2010) Y Deng et al.   ONCOGENE

Altered Proliferation and Differentiation Properties of Primary Mammary Epithelial Cells from BRCA1 Mutation Carriers

(2009) Laura N. Burga et al.   CANCER RESEARCH

BRCA1 modulates malignant cell behavior, the expression of survivin and chemosensitivity in human breast cancer cells

(2009) Moltira Promkan et al.   INTERNATIONAL JOURNAL OF CANCER

Mechanism of BRCA1-Mediated Inhibition of Progesterone Receptor Transcriptional Activity

(2009) Pragati Katiyar et al.   MOLECULAR ENDOCRINOLOGY

Decreased BRCA1 confers tamoxifen resistance in breast cancer cells by altering estrogen receptor–coregulator interactions

(2008) J Wen et al.   ONCOGENE