Visfatin/Nampt: An Adipokine with Cardiovascular Impact

Visfatin induces cholesterol accumulation in macrophages through up-regulation of scavenger receptor-A and CD36

(2013) Fenghua Zhou et al.   CELL STRESS & CHAPERONES

Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors as Therapeutics: Rationales, Controversies, Clinical Experience

(2013) By Fabrizio Montecucco et al.   CURRENT DRUG TARGETS

Circulating levels of novel adipocytokines in patients with colorectal cancer

(2013) Mohammad Sadegh Fazeli et al.   CYTOKINE

Visfatin, a potential biomarker and prognostic factor for endometrial cancer

(2013) Wenyan Tian et al.   GYNECOLOGIC ONCOLOGY

Nampt secreted from cardiomyocytes promotes development of cardiac hypertrophy and adverse ventricular remodeling

(2012) Vinodkumar B. Pillai et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Inhibition of Nicotinamide Phosphoribosyltransferase Reduces Neutrophil-Mediated Injury in Myocardial Infarction

(2012) Fabrizio Montecucco et al.   ANTIOXIDANTS & REDOX SIGNALING

Upregulation of thromboxane synthase mediates visfatin-induced interleukin-8 expression and angiogenic activity in endothelial cells

(2012) Su-Ryun Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Proinflammatory Actions of Visfatin/Nicotinamide Phosphoribosyltransferase (Nampt) Involve Regulation of Insulin Signaling Pathway and Nampt Enzymatic Activity

(2012) Claire Jacques et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Maternal serum visfatin at 11–13 weeks’ gestation in preeclampsia

(2012) A F A Ferreira et al.   JOURNAL OF HUMAN HYPERTENSION

Decreased expressions of vascular endothelial growth factor and visfatin in the placental bed of pregnancies complicated by preeclampsia

(2012) Seung-Chul Kim et al.   JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH

Increased Expression of Visfatin in Monocytes and Macrophages in Male Acute Myocardial Infarction Patients

(2012) Cheng-An Chiu et al.   MEDIATORS OF INFLAMMATION

Role of Adipokines in Atherosclerosis: Interferences with Cardiovascular Complications in Rheumatic Diseases

(2012) Morena Scotece et al.   MEDIATORS OF INFLAMMATION

Nicotinamide phosphoribosyltransferase protects against ischemic stroke through SIRT1-dependent adenosine monophosphate-activated kinase pathway

(2011) Pei Wang et al.   ANNALS OF NEUROLOGY

Evidence for visfatin as an independent predictor of endothelial dysfunction in polycystic ovary syndrome

(2011) Carmen E. Pepene   CLINICAL ENDOCRINOLOGY

The level of serum visfatin (PBEF) is associated with total number of B cells in patients with rheumatoid arthritis and decreases following B cell depletion therapy

(2011) Ladislav Šenolt et al.   CYTOKINE

Interpretation of elevated plasma visfatin concentrations in patients with ST-elevation myocardial infarction

(2011) Li-Fen Lu et al.   CYTOKINE

Dipeptidyl Peptidase 4 Is a Novel Adipokine Potentially Linking Obesity to the Metabolic Syndrome

(2011) D. Lamers et al.   DIABETES

Visfatin Stimulates a Cellular Renin-Angiotensin System in Cultured Rat Mesangial Cells

(2011) Qiong Huang et al.   ENDOCRINE RESEARCH

Leptin, adiponectin, visfatin and retinol-binding protein-4 - mediators of comorbidities in patients with psoriasis?

(2011) Sascha Gerdes et al.   EXPERIMENTAL DERMATOLOGY

Adipokines in Periaortic and Epicardial Adipose Tissue: Differential Expression and Relation to Atherosclerosis

(2011) Sofia G. Spiroglou et al.   Journal of Atherosclerosis and Thrombosis

Visfatin Impairs Endothelium-Dependent Relaxation in Rat and Human Mesenteric Microvessels through Nicotinamide Phosphoribosyltransferase Activity

(2011) Susana Vallejo et al.   PLoS One

Visfatin-induced lipid raft redox signaling platforms and dysfunction in glomerular endothelial cells

(2010) Krishna M. Boini et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Peripheral blood gene expression patterns discriminate among chronic inflammatory diseases and healthy controls and identify novel targets

(2010) Bertalan Mesko et al.   BMC Medical Genomics

Membrane raft–lysosome redox signalling platforms in coronary endothelial dysfunction induced by adipokine visfatin

(2010) Min Xia et al.   CARDIOVASCULAR RESEARCH

Visfatin/PBEF and Atherosclerosis-Related Diseases

(2010) Theodosios Filippatos et al.   Current Vascular Pharmacology

Effects of Visfatin on Proliferation and Collagen Synthesis in Rat Cardiac Fibroblasts

(2010) X-Y. Yu et al.   HORMONE AND METABOLIC RESEARCH

Visfatin/PBEF/Nampt and Resistin Expressions in Circulating Blood Monocytes are Differentially Related to Obesity and Type 2 Diabetes in Humans

(2010) M. Laudes et al.   HORMONE AND METABOLIC RESEARCH

Reactive oxygen species and vascular biology: implications in human hypertension

(2010) Rhian M Touyz et al.   HYPERTENSION RESEARCH

Neuronal Protective Role of PBEF in a Mouse Model of Cerebral Ischemia

(2010) Weiping Zhang et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Pre-eclampsia

(2010) Eric AP Steegers et al.   LANCET

Visfatin activates eNOS via Akt and MAP kinases and improves endothelial cell function and angiogenesis in vitro and in vivo: translational implications for atherosclerosis

(2009) Fina Lovren et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Skeletal muscle NAMPT is induced by exercise in humans

(2009) Sheila R. Costford et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Plasma visfatin levels in preeclamptic and normal pregnancies

(2009) Ebru Zulfıkaroglu et al.   ARCHIVES OF GYNECOLOGY AND OBSTETRICS

Visfatin causes endothelium-dependent relaxation in isolated blood vessels

(2009) Hideyuki Yamawaki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Nicotinamide phosphoribosyltransferase (NAMPT/PBEF/visfatin) is constitutively released from human hepatocytes

(2009) A. Garten et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Detection and pharmacological modulation of nicotinamide mononucleotide (NMN) in vitro and in vivo

(2009) Laura Formentini et al.   BIOCHEMICAL PHARMACOLOGY

Endothelial Dysfunction

(2009) Paul M. Vanhoutte   CIRCULATION JOURNAL

Nicotinamide Phosphoribosyltransferase Regulates Cell Survival Through NAD + Synthesis in Cardiac Myocytes

(2009) Chiao-Po Hsu et al.   CIRCULATION RESEARCH

Association of plasma visfatin levels with inflammation, atherosclerosis and acute coronary syndromes (ACS) in humans

(2009) Sheng Wen Liu et al.   CLINICAL ENDOCRINOLOGY

Normalization of endothelial dysfunction following renal transplantation is accompanied by a reduction of circulating visfatin/NAMPT. A novel marker of endothelial damage?

(2009) Mahmut Ilker Yilmaz et al.   CLINICAL TRANSPLANTATION

Nicotinamide Phosphoribosyltransferase (Nampt): A Link Between NAD Biology, Metabolism, and Diseases

(2009) Shin-ichiro Imai   CURRENT PHARMACEUTICAL DESIGN

Involvement of dimethylarginine dimethylaminohydrolase-2 in visfatin-enhanced angiogenic function of endothelial cells

(2009) Jian Xiao et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Extracellular PBEF/NAMPT/visfatin activates pro-inflammatory signalling in human vascular smooth muscle cells through nicotinamide phosphoribosyltransferase activity

(2009) T. Romacho et al.   DIABETOLOGIA

Visfatin (Nampt) and Ghrelin as Novel Markers of Carotid Atherosclerosis in Patients with Type 2 Diabetes

(2009) N. P. E. Kadoglou et al.   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

SIRT1 markedly extends replicative lifespan if the NAD+salvage pathway is enhanced

(2009) Cynthia Ho et al.   FEBS LETTERS

Visfatin-induced expression of inflammatory mediators in human endothelial cells through the NF-κB pathway

(2009) W-J Lee et al.   INTERNATIONAL JOURNAL OF OBESITY

Adipocytokine levels in gastric cancer patients: resistin and visfatin as biomarkers of gastric cancer

(2009) Takako Eguchi Nakajima et al.   JOURNAL OF GASTROENTEROLOGY

Elevated Visfatin/Pre-B-cell Colony-enhancing Factor Plasma Concentration in Ischemic Stroke

(2009) Li-Fen Lu et al.   Journal of Stroke & Cerebrovascular Diseases

Visfatin, a New Adipocytokine, Is Predominantly Related to Inflammation/Endothelial Damage in Kidney Allograft Recipients

(2009) J. Malyszko et al.   TRANSPLANTATION PROCEEDINGS

Serum visfatin levels in late pregnancy and pre-eclampsia

(2008) Wensheng Hu et al.   ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA

Visfatin and apelin, new adipocytokines, and their relation to endothelial function in patients with chronic renal failure

(2008) J Malyszko et al.   Advances in Medical Sciences

Relationship between Serum Pre-B Cell Colony-Enhancing Factor/Visfatin and Atherosclerotic Parameters in Chronic Hemodialysis Patients

(2008) Akihiko Kato et al.   AMERICAN JOURNAL OF NEPHROLOGY

Crucial role of visfatin/pre–B cell colony-enhancing factor in matrix degradation and prostaglandin E2 synthesis in chondrocytes: Possible influence on osteoarthritis

(2008) Marjolaine Gosset et al.   ARTHRITIS AND RHEUMATISM

Pre-B cell colony enhancing factor (PBEF)/visfatin induces secretion of MCP-1 in human endothelial cells: Role in visfatin-induced angiogenesis

(2008) Raghu Adya et al.   ATHEROSCLEROSIS

Upregulation of fibroblast growth factor-2 by visfatin that promotes endothelial angiogenesis

(2008) Yun-Hee Bae et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Visfatin enhances ICAM-1 and VCAM-1 expression through ROS-dependent NF-κB activation in endothelial cells

(2008) Su-Ryun Kim et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Perivascular adipose tissue-derived visfatin is a vascular smooth muscle cell growth factor: role of nicotinamide mononucleotide

(2008) Pei Wang et al.   CARDIOVASCULAR RESEARCH

Serum levels of the adipokine visfatin are increased in pre-eclampsia

(2008) Mathias Fasshauer et al.   CLINICAL ENDOCRINOLOGY

Increased serum visfatin in patients with metabolic syndrome and carotid atherosclerosis

(2008) Ming Zhong et al.   CLINICAL ENDOCRINOLOGY

Visfatin/PBEF/Nampt: structure, regulation and potential function of a novel adipokine

(2008) Grit Sommer et al.   CLINICAL SCIENCE

Nuclear Factor- B Induction by Visfatin in Human Vascular Endothelial Cells: Its role in MMP-2/9 production and activation

(2008) R. Adya et al.   DIABETES CARE

Gene Expression of Endothelial Cells due to Interleukin-1 Beta Stimulation and Neutrophil Transmigration

(2008) Marcie R. Williams et al.   ENDOTHELIUM-JOURNAL OF ENDOTHELIAL CELL RESEARCH

Visfatin Stimulates Production of Monocyte Chemotactic Protein-1 and Interleukin-6 in Human Vein Umbilical Endothelial Cells

(2008) S. Liu et al.   HORMONE AND METABOLIC RESEARCH

Extracellular Nampt Promotes Macrophage Survival via a Nonenzymatic Interleukin-6/STAT3 Signaling Mechanism

(2008) Yankun Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The novel adipocytokine visfatin exerts direct cardioprotective effects

(2008) Shiang Y. Lim et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Epicardial fat thickness: Relationship with plasma visfatin and plasminogen activator inhibitor-1 levels in visceral obesity

(2008) Alexis E. Malavazos et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Pharmacological Inhibition of Nicotinamide Phosphoribosyltransferase/Visfatin Enzymatic Activity Identifies a New Inflammatory Pathway Linked to NAD

(2008) Nathalie Busso et al.   PLoS One

Comparison of MMP-2 and MMP-9 secretion from T helper 0, 1 and 2 lymphocytes alone and in coculture with macrophages

(2007) Ernesto Oviedo-Orta et al.   IMMUNOLOGY