An AKT/PRMT5/SREBP1 axis in lung adenocarcinoma regulates de novo lipogenesis and tumor growth
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Title
An AKT/PRMT5/SREBP1 axis in lung adenocarcinoma regulates de novo lipogenesis and tumor growth
Authors
Keywords
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Journal
CANCER SCIENCE
Volume 112, Issue 8, Pages 3083-3098
Publisher
Wiley
Online
2021-05-25
DOI
10.1111/cas.14988
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- (2020) Lindsay M. Webb et al. JOURNAL OF CLINICAL INVESTIGATION
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- (2020) Bo Zhang et al. OncoTargets and Therapy
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- (2019) Xiao Li et al. EXPERT OPINION ON THERAPEUTIC PATENTS
- Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity
- (2019) Kim Vriens et al. NATURE
- AKT as a Therapeutic Target for Cancer
- (2019) Mengqiu Song et al. CANCER RESEARCH
- PRMT5 is upregulated by B-cell receptor signaling and forms a positive-feedback loop with PI3K/AKT in lymphoma cells
- (2019) Fen Zhu et al. LEUKEMIA
- Cancer treatment and survivorship statistics, 2019
- (2019) Kimberly D. Miller et al. CA-A CANCER JOURNAL FOR CLINICIANS
- PI3K/Akt/mTOR inhibitors in cancer: At the bench and bedside
- (2019) Ali S. Alzahrani SEMINARS IN CANCER BIOLOGY
- Akt in cancer: Mediator and more
- (2019) Sundaramoorthy Revathidevi et al. SEMINARS IN CANCER BIOLOGY
- SREBP1 drives Keratin-80-dependent cytoskeletal changes and invasive behavior in endocrine-resistant ERα breast cancer
- (2019) Ylenia Perone et al. Nature Communications
- Targeting AKT for cancer therapy
- (2019) Maryam Shariati et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Cancer statistics, 2018
- (2018) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Role of hepatoma-derived growth factor in promoting de novo lipogenesis and tumorigenesis in hepatocellular carcinoma
- (2018) Xuejie Min et al. Molecular Oncology
- SREBPs in Lipid Metabolism, Insulin Signaling, and Beyond
- (2018) Russell A. DeBose-Boyd et al. TRENDS IN BIOCHEMICAL SCIENCES
- The LINC01138 interacts with PRMT5 to promote SREBP1-mediated lipid desaturation and cell growth in clear cell renal cell carcinoma
- (2018) Xi Zhang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Targeting PRMT5/Akt signalling axis prevents human lung cancer cell growth
- (2018) Shikui Zhang et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Targeting protein arginine methyltransferase 5 in disease
- (2017) André Richters Future Medicinal Chemistry
- Pleiotrophin, a target of miR-384, promotes proliferation, metastasis and lipogenesis in HBV-related hepatocellular carcinoma
- (2017) Pei-song Bai et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Fatty acid synthase – Modern tumor cell biology insights into a classical oncology target
- (2017) Douglas Buckley et al. PHARMACOLOGY & THERAPEUTICS
- Arginine Methylation of SREBP1a via PRMT5 Promotes De Novo Lipogenesis and Tumor Growth
- (2016) L. Liu et al. CANCER RESEARCH
- The IASLC Lung Cancer Staging Project: Proposals for Revision of the TNM Stage Groupings in the Forthcoming (Eighth) Edition of the TNM Classification for Lung Cancer
- (2016) Peter Goldstraw et al. Journal of Thoracic Oncology
- PRMT5 competitively binds to CDK4 to promote G1-S transition upon glucose induction in hepatocellular carcinoma
- (2016) Hao Yang et al. Oncotarget
- Inhibition of SREBP increases gefitinib sensitivity in non-small cell lung cancer cells
- (2016) Jiajin Li et al. Oncotarget
- Feedback Loop Regulation of SCAP/SREBP-1 by miR-29 Modulates EGFR Signaling-Driven Glioblastoma Growth
- (2016) Peng Ru et al. Cell Reports
- Glucose-Mediated N-glycosylation of SCAP Is Essential for SREBP-1 Activation and Tumor Growth
- (2015) Chunming Cheng et al. CANCER CELL
- p54nrb/NONO regulates lipid metabolism and breast cancer growth through SREBP-1A
- (2015) Z Zhu et al. ONCOGENE
- Targeting PI3K/AKT/mTOR pathway in non small cell lung cancer
- (2014) Claudia Fumarola et al. BIOCHEMICAL PHARMACOLOGY
- Expression of PRMT5 in lung adenocarcinoma and its significance in epithelial-mesenchymal transition
- (2014) Reem Ibrahim et al. HUMAN PATHOLOGY
- Cellular localization of protein arginine methyltransferase-5 correlates with grade of lung tumors
- (2013) Konstantin Shilo et al. Diagnostic Pathology
- Small molecule-induced cytosolic activation of protein kinase Akt rescues ischemia-elicited neuronal death
- (2012) H. Jo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Positive Feedback Loop Between PI3K-Akt-mTORC1 Signaling and the Lipogenic Pathway Boosts Akt Signaling: Induction of the Lipogenic Pathway by a Melanoma Antigen
- (2011) Y. Yamauchi et al. CANCER RESEARCH
- An LXR Agonist Promotes Glioblastoma Cell Death through Inhibition of an EGFR/AKT/SREBP-1/LDLR-Dependent Pathway
- (2011) D. Guo et al. Cancer Discovery
- The Akt–SREBP nexus: cell signaling meets lipid metabolism
- (2010) James R. Krycer et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- GFAP, Ki67 and IDH1: perhaps the golden triad of glioma immunohistochemistry
- (2009) Werner Paulus ACTA NEUROPATHOLOGICA
- Insulin Enhances Post-translational Processing of Nascent SREBP-1c by Promoting Its Phosphorylation and Association with COPII Vesicles
- (2009) Chandrahasa R. Yellaturu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- EGFR Signaling Through an Akt-SREBP-1-Dependent, Rapamycin-Resistant Pathway Sensitizes Glioblastomas to Antilipogenic Therapy
- (2009) D. Guo et al. Science Signaling
- Fatty Acid Synthase Gene Is Up-regulated by Hypoxia via Activation of Akt and Sterol Regulatory Element Binding Protein-1
- (2008) E. Furuta et al. CANCER RESEARCH
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