Targeting PRMT5/Akt signalling axis prevents human lung cancer cell growth

PRMT5 promotes cell proliferation by inhibiting BTG2 expression via the ERK signaling pathway in hepatocellular carcinoma

(2018) Hai Jiang et al.   Cancer Medicine

Protein arginine methyltransferase 5 regulates multiple signaling pathways to promote lung cancer cell proliferation

(2016) Xiumei Sheng et al.   BMC CANCER

Arginine Methylation of SREBP1a via PRMT5 Promotes De Novo Lipogenesis and Tumor Growth

(2016) L. Liu et al.   CANCER RESEARCH

Protein arginine methyltransferase 5 is associated with malignant phenotype and peritoneal metastasis in gastric cancer

(2016) Mitsuro Kanda et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Targeting methyltransferase PRMT5 eliminates leukemia stem cells in chronic myelogenous leukemia

(2016) Yanli Jin et al.   JOURNAL OF CLINICAL INVESTIGATION

The PRMT5 arginine methyltransferase: many roles in development, cancer and beyond

(2015) Nicole Stopa et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

PRMT5 Is Required for Lymphomagenesis Triggered by Multiple Oncogenic Drivers

(2015) Y. Li et al.   Cancer Discovery

Control of cell cycle transcription during G1 and S phases

(2013) Cosetta Bertoli et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Protein arginine methyltransferase 5 is a potential oncoprotein that upregulates G1 cyclins/cyclin-dependent kinases and the phosphoinositide 3-kinase/AKT signaling cascade

(2012) Tong-You W. Wei et al.   CANCER SCIENCE

Arginine methylation controls growth regulation by E2F-1

(2012) Er-Chieh Cho et al.   EMBO JOURNAL

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Nuclear Cyclin D1/CDK4 Kinase Regulates CUL4 Expression and Triggers Neoplastic Growth via Activation of the PRMT5 Methyltransferase

(2010) Priya Aggarwal et al.   CANCER CELL

High fluence low-power laser irradiation induces apoptosis via inactivation of Akt/GSK3β signaling pathway

(2010) Lei Huang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Eukaryotic Initiation Factor-4E and Cyclin D1 Expression Associated with Patient Survival in Lung Cancer

(2009) Thaer Khoury et al.   Clinical Lung Cancer

GSK-3β regulates cyclin D1 expression: A new target for chemotherapy

(2007) Fumi Takahashi-Yanaga et al.   CELLULAR SIGNALLING