Synthesis and comparison of in vitro dual anti-infective activities of novel naphthoquinone hybrids and atovaquone
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Title
Synthesis and comparison of in vitro dual anti-infective activities of novel naphthoquinone hybrids and atovaquone
Authors
Keywords
Drug design, Molecular hybridization, 1,4-naphthoquinone, 1,2,3-triazole, Click-chemistry
Journal
BIOORGANIC CHEMISTRY
Volume 114, Issue -, Pages 105118
Publisher
Elsevier BV
Online
2021-06-24
DOI
10.1016/j.bioorg.2021.105118
References
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Note: Only part of the references are listed.- Inhibitory Effect of Lygodium Root on the Cytochrome P450 3A Enzyme in vitro and in vivo
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- (2020) Magnus Ingelman-Sundberg et al. TRENDS IN PHARMACOLOGICAL SCIENCES
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- (2020) Mariano Walter Pertino et al. BIOORGANIC CHEMISTRY
- Effects of Naphthazarin (DHNQ) Combined with Lawsone (NQ-2-OH) or 1,4-Naphthoquinone (NQ) on the Auxin-Induced Growth of Zea mays L. Coleoptile Segments
- (2019) Małgorzata Rudnicka et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Synthesis and antiproliferative evaluation of some 1,4-naphthoquinone derivatives against human cervical cancer cells
- (2019) Aysecik Kacmaz et al. Open Chemistry
- Click chemistry-assisted synthesis of novel aminonaphthoquinone-1,2,3-triazole hybrids and investigation of their cytotoxicity and cancer cell cycle alterations
- (2019) Maryam Gholampour et al. BIOORGANIC CHEMISTRY
- The diverse mechanisms and anticancer potential of naphthoquinones
- (2019) Carolina Escardó Pereyra et al. Cancer Cell International
- Microtiter Screening Reveals Oxygen-Dependent Antimicrobial Activity of Natural Products Against Mastitis-Causing Bacteria
- (2019) Scott A. Ferguson et al. Frontiers in Microbiology
- Antifungal Activity of Euclea divinorum Root and Study of its Ethnobotany and Phytopharmacology
- (2019) Al-Fatimi Processes
- Synthesis and Antiplasmodial Activity of 1,2,3-Triazole-Naphthoquinone Conjugates
- (2019) Oramas-Royo et al. MOLECULES
- The natural compound gracillin exerts potent antitumor activity by targeting mitochondrial complex II
- (2019) Hye-Young Min et al. Cell Death & Disease
- Comparison of Antifungal Azole Interactions with Adult Cytochrome P450 3A4 vs. Neonatal Cytochrome P450 3A7
- (2018) Malika P. Godamudunage et al. DRUG METABOLISM AND DISPOSITION
- Potential Antileishmanial Activity of a Triazole-Based Hybrid Peptide against Leishmania major
- (2018) Krishnendu Maji et al. ChemistrySelect
- In vivo antileishmanial efficacy of a naphthoquinone derivate incorporated into a Pluronic® F127-based polymeric micelle system against Leishmania amazonensis infection
- (2018) Débora V.C. Mendonça et al. BIOMEDICINE & PHARMACOTHERAPY
- Triazole derivatives and their anti-tubercular activity
- (2017) Shu Zhang et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Novel Antitubercular 6-Dialkylaminopyrimidine Carboxamides from Phenotypic Whole-Cell High Throughput Screening of a SoftFocus Library: Structure–Activity Relationship and Target Identification Studies
- (2017) Colin R. Wilson et al. JOURNAL OF MEDICINAL CHEMISTRY
- Naphthoquinones of Sinningia reitzii and Anti-inflammatory/Antinociceptive Activities of 8-Hydroxydehydrodunnione
- (2017) Adson S. Soares et al. JOURNAL OF NATURAL PRODUCTS
- Assessment of the inhibition risk of shikonin on cytochrome P450 via cocktail inhibition assay
- (2017) Shuowen Tang et al. TOXICOLOGY LETTERS
- Increased miltefosine tolerance in clinical isolates of Leishmania donovani is associated with reduced drug accumulation, increased infectivity and resistance to oxidative stress
- (2017) Deepak Kumar Deep et al. PLoS Neglected Tropical Diseases
- Drug resistance and treatment failure in leishmaniasis: A 21st century challenge
- (2017) Alicia Ponte-Sucre et al. PLoS Neglected Tropical Diseases
- Exploring the Role of CYP3A4 Mediated Drug Metabolism in the Pharmacological Modulation of Nitric Oxide Production
- (2017) José Pérez-del Palacio et al. Frontiers in Pharmacology
- SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules
- (2017) Antoine Daina et al. Scientific Reports
- Bioluminescent Reporters for Rapid Mechanism of Action Assessment in Tuberculosis Drug Discovery
- (2016) Krupa Naran et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Plumbagin, a plant-derived naphthoquinone metabolite induces mitochondria mediated apoptosis-like cell death in Leishmania donovani: an ultrastructural and physiological study
- (2016) Bhanu Priya Awasthi et al. APOPTOSIS
- Effects of juglone and lawsone on oxidative stress in maize coleoptile cells treated with IAA
- (2016) Renata Kurtyka et al. AoB Plants
- Evaluation of the inhibition potential of plumbagin against cytochrome P450 using LC-MS/MS and cocktail approach
- (2016) Ang Chen et al. Scientific Reports
- Hit and lead criteria in drug discovery for infectious diseases of the developing world
- (2015) Kei Katsuno et al. NATURE REVIEWS DRUG DISCOVERY
- Interactions between CYP3A4 and Dietary Polyphenols
- (2015) Loai Basheer et al. Oxidative Medicine and Cellular Longevity
- The potential impact of coinfection on antimicrobial chemotherapy and drug resistance
- (2015) Ruthie B. Birger et al. TRENDS IN MICROBIOLOGY
- Are 1,4- and 1,5-Disubstituted 1,2,3-Triazoles Good Pharmacophoric Groups?
- (2014) Alberto Massarotti et al. ChemMedChem
- Sequential synthesis of amino-1,4-naphthoquinone-appended triazoles and triazole-chromene hybrids and their antimycobacterial evaluation
- (2014) Balasubramanian Devi Bala et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Auto-induction of phase I and phase II metabolism of artemisinin in healthy Chinese subjects after oral administration of a new artemisinin-piperaquine fixed combination
- (2014) Meitong Zang et al. MALARIA JOURNAL
- Antimalarial pharmacology and therapeutics of atovaquone
- (2013) G. L. Nixon et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Co-infection of tuberculosis and parasitic diseases in humans: a systematic review
- (2013) Xin-Xu Li et al. Parasites & Vectors
- An unexpected copper catalyzed ‘reduction’ of an arylazide to amine through the formation of a nitrene intermediate
- (2013) Hanjing Peng et al. TETRAHEDRON
- 1,2,3-Triazole–Heme Interactions in Cytochrome P450: Functionally Competent Triazole–Water–Heme Complexes
- (2012) Kip P. Conner et al. BIOCHEMISTRY
- The Naphthoquinone Diospyrin Is an Inhibitor of DNA Gyrase with a Novel Mechanism of Action
- (2012) Shantanu Karkare et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Copper-Catalyzed Azide–Alkyne Cycloaddition Reaction in Water Using Cyclodextrin as a Phase Transfer Catalyst
- (2012) Jung-Ah Shin et al. JOURNAL OF ORGANIC CHEMISTRY
- Validation of a simple resazurin-based promastigote assay for the routine monitoring of miltefosine susceptibility in clinical isolates of Leishmania donovani
- (2012) Arpita Kulshrestha et al. PARASITOLOGY RESEARCH
- An Image-Based High-Content Screening Assay for Compounds Targeting Intracellular Leishmania donovani Amastigotes in Human Macrophages
- (2012) Jair L. Siqueira-Neto et al. PLoS Neglected Tropical Diseases
- Revisiting the General Solubility Equation: In Silico Prediction of Aqueous Solubility Incorporating the Effect of Topographical Polar Surface Area
- (2011) Jogoth Ali et al. Journal of Chemical Information and Modeling
- Stereoselective anti-SN2′ Mitsunobu reaction of α-hydroxy-α-alkenylsilanes
- (2010) Masato Higashino et al. TETRAHEDRON LETTERS
- Trifluoromethyl ethers – synthesis and properties of an unusual substituent
- (2008) Frédéric R Leroux et al. Beilstein Journal of Organic Chemistry
- The aza-analogues of 1,4-naphthoquinones are potent substrates and inhibitors of plasmodial thioredoxin and glutathione reductases and of human erythrocyte glutathione reductase
- (2008) Christophe Morin et al. ORGANIC & BIOMOLECULAR CHEMISTRY
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