- Home
- Publications
- Publication Search
- Publication Details
Title
The diverse mechanisms and anticancer potential of naphthoquinones
Authors
Keywords
Naphthoquinones, Natural compounds, Multi-target agents, Chemotherapy, Cancer drug discovery
Journal
Cancer Cell International
Volume 19, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-08-02
DOI
10.1186/s12935-019-0925-8
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The Role of the ER-Induced UPR Pathway and the Efficacy of Its Inhibitors and Inducers in the Inhibition of Tumor Progression
- (2019) Anna Walczak et al. Oxidative Medicine and Cellular Longevity
- Role of Endoplasmic Reticulum Stress in the Anticancer Activity of Natural Compounds
- (2019) Patrizia Limonta et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Endoplasmic Reticulum Stress in Metabolic Disorders
- (2018) Rose Ghemrawi et al. Cells
- Emerging roles of ER stress in the etiology and pathogenesis of Alzheimer's disease
- (2017) Yannis Gerakis et al. FEBS Journal
- Phantom PAINS: Problems with the Utility of Alerts for Pan-Assay INterference CompoundS
- (2017) Stephen J. Capuzzi et al. Journal of Chemical Information and Modeling
- Endoplasmic reticulum stress, the unfolded protein response and autophagy in kidney diseases
- (2017) Andrey V. Cybulsky Nature Reviews Nephrology
- Activity profiles of analog series containing pan assay interference compounds
- (2017) Erik Gilberg et al. RSC Advances
- The p53 Pathway: Origins, Inactivation in Cancer, and Emerging Therapeutic Approaches
- (2016) Andreas C. Joerger et al. Annual Review of Biochemistry
- In vivo inhibition of tumor progression by 5 hydroxy-1,4-naphthoquinone (juglone) and 2-(4-hydroxyanilino)-1,4-naphthoquinone (Q7) in combination with ascorbate
- (2016) Fabiana Ourique et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Novel juglone and plumbagin 5- O derivatives and their in vitro growth inhibitory activity against apoptosis-resistant cancer cells
- (2016) Serena Fiorito et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Filtering promiscuous compounds in early drug discovery: is it a good idea?
- (2016) Mario R. Senger et al. DRUG DISCOVERY TODAY
- 2-Methoxy-6-acetyl-7-methyljuglone (MAM), a natural naphthoquinone, induces NO-dependent apoptosis and necroptosis by H 2 O 2 -dependent JNK activation in cancer cells
- (2016) Wen Sun et al. FREE RADICAL BIOLOGY AND MEDICINE
- Highly Promiscuous Small Molecules from Biological Screening Assays Include Many Pan-Assay Interference Compounds but Also Candidates for Polypharmacology
- (2016) Erik Gilberg et al. JOURNAL OF MEDICINAL CHEMISTRY
- Feeling Nature’s PAINS: Natural Products, Natural Product Drugs, and Pan Assay Interference Compounds (PAINS)
- (2016) Jonathan B. Baell JOURNAL OF NATURAL PRODUCTS
- Understanding and predicting the potency of ROS-based enzyme inhibitors, exemplified by naphthoquinones and ubiquitin specific protease-2
- (2016) Pushparathinam Gopinath et al. Chemical Science
- Molecular hybridization as a powerful tool towards multitarget quinoidal systems: synthesis, trypanocidal and antitumor activities of naphthoquinone-based 5-iodo-1,4-disubstituted-, 1,4- and 1,5-disubstituted-1,2,3-triazoles
- (2016) Samara Ben B. B. Bahia et al. MedChemComm
- A direct interaction between NQO1 and a chemotherapeutic dimeric naphthoquinone
- (2016) Lakshmi Swarna Mukhi Pidugu et al. BMC STRUCTURAL BIOLOGY
- Enhanced antitumor effect of shikonin by inhibiting Endoplasmic Reticulum Stress via JNK/c-Jun pathway in human glioblastoma stem cells
- (2015) Jing Liu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Shikonin causes apoptosis by up-regulating p73 and down-regulating ICBP90 in human cancer cells
- (2015) Soon Young Jang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Shikonin causes cell-cycle arrest and induces apoptosis by regulating the EGFR–NF-κB signalling pathway in human epidermoid carcinoma A431 cells
- (2015) Rong Tian et al. BIOSCIENCE REPORTS
- The role of thioredoxin reductase and glutathione reductase in plumbagin-induced, reactive oxygen species-mediated apoptosis in cancer cell lines
- (2015) Geun Hye Hwang et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Shikonin and its derivatives inhibit the epidermal growth factor receptor signaling and synergistically kill glioblastoma cells in combination with erlotinib
- (2015) Qiaoli Zhao et al. INTERNATIONAL JOURNAL OF CANCER
- Downregulation of Sp1 is involved in β-lapachone-induced cell cycle arrest and apoptosis in oral squamous cell carcinoma
- (2015) YOUNG-JOO JEON et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Antitumorigenic effect of plumbagin by induction of SH2-containing protein tyrosine phosphatase 1 in human gastric cancer cells
- (2015) MOON KYUNG JOO et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Identification of β-Lapachone Analogs as Novel MALT1 Inhibitors To Treat an Aggressive Subtype of Diffuse Large B-Cell Lymphoma
- (2015) Sang Min Lim et al. JOURNAL OF MEDICINAL CHEMISTRY
- 2-Methoxy-1,4-naphthoquinone (MNQ) induces apoptosis of A549 lung adenocarcinoma cells via oxidation-triggered JNK and p38 MAPK signaling pathways
- (2015) Jeremy Yee Hoong Ong et al. LIFE SCIENCES
- Synthesis and Biological Evaluation of Lipophilic 1,4-Naphthoquinone Derivatives against Human Cancer Cell Lines
- (2015) Shao-Hung Wang et al. MOLECULES
- Plumbagin alters telomere dynamics, induces DNA damage and cell death in human brain tumour cells
- (2015) Aik Kia Khaw et al. MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
- Understanding cancer and the anticancer activities of naphthoquinones – a review
- (2015) Kevin W. Wellington RSC Advances
- NQO1-induced activation of AMPK contributes to cancer cell death by oxygen-glucose deprivation
- (2015) Hyemi Lee et al. Scientific Reports
- UDP-Glucuronosyltransferase 1A Determinates Intracellular Accumulation and Anti-Cancer Effect of β-Lapachone in Human Colon Cancer Cells
- (2015) Huiying Liu et al. PLoS One
- Synthesis and evaluation of the cytotoxic activity of 1,2-furanonaphthoquinones tethered to 1,2,3-1H-triazoles in myeloid and lymphoid leukemia cell lines
- (2014) Mariana F.C. Cardoso et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Synthesis and Cytotoxic Evaluation of a Series of 2-Amino-Naphthoquinones against Human Cancer Cells
- (2014) Thiago de Moraes et al. MOLECULES
- The Protective Role of Antioxidants in the Defence against ROS/RNS-Mediated Environmental Pollution
- (2014) Borut Poljšak et al. Oxidative Medicine and Cellular Longevity
- Antiproliferative activities and SAR studies of substituted anthraquinones and 1,4-naphthoquinones
- (2013) Deepak Bhasin et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Cysteine-Mediated Redox Signaling: Chemistry, Biology, and Tools for Discovery
- (2013) Candice E. Paulsen et al. CHEMICAL REVIEWS
- Synergistic enhancement of antitumor effect of β-Lapachone by photodynamic induction of quinone oxidoreductase (NQO1)
- (2013) María Julia Lamberti et al. PHYTOMEDICINE
- Topoisomerase I Inhibitors, Shikonin and Topotecan, Inhibit Growth and Induce Apoptosis of Glioma Cells and Glioma Stem Cells
- (2013) Feng-Lei Zhang et al. PLoS One
- Novel Multiple Apoptotic Mechanism of Shikonin in Human Glioma Cells
- (2012) Ching-Hsein Chen et al. ANNALS OF SURGICAL ONCOLOGY
- An NQO1 Substrate with Potent Antitumor Activity That Selectively Kills by PARP1-Induced Programmed Necrosis
- (2012) X. Huang et al. CANCER RESEARCH
- Reviews on 1,4-naphthoquinones fromDiospyrosL.
- (2012) Alireza Nematollahi et al. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
- NAD(P)H:quinone oxidoreductase 1 (NQO1) in the sensitivity and resistance to antitumor quinones
- (2011) David Siegel et al. BIOCHEMICAL PHARMACOLOGY
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Dietary oxidative stress and antioxidant defense with an emphasis on plant extract administration
- (2011) Aristidis S. Veskoukis et al. CELL STRESS & CHAPERONES
- β-Lapachone Significantly Increases the Effect of Ionizing Radiation to Cause Mitochondrial Apoptosis via JNK Activation in Cancer Cells
- (2011) Moon-Taek Park et al. PLoS One
- Profiling the NIH Small Molecule Repository for Compounds That Generate H2O2 by Redox Cycling in Reducing Environments
- (2010) Karina M. Soares et al. ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES
- Recent Advances in the Development of Dual Topoisomerase I and II Inhibitors as Anticancer Drugs
- (2010) S. Salerno et al. CURRENT MEDICINAL CHEMISTRY
- Biological evaluation of donor-acceptor aminonaphthoquinones as antitumor agents
- (2010) Julio Benites et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- New Substructure Filters for Removal of Pan Assay Interference Compounds (PAINS) from Screening Libraries and for Their Exclusion in Bioassays
- (2010) Jonathan B. Baell et al. JOURNAL OF MEDICINAL CHEMISTRY
- 8-hydroxy-2′ -deoxyguanosine (8-OHdG): A Critical Biomarker of Oxidative Stress and Carcinogenesis
- (2009) ATHANASIOS VALAVANIDIS et al. JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART C-ENVIRONMENTAL CARCINOGENESIS & ECOTOXICOLOGY REVIEWS
- Shikonin exerts antitumor activityviaproteasome inhibition and cell death inductionin vitroandin vivo
- (2008) Huanjie Yang et al. INTERNATIONAL JOURNAL OF CANCER
- Cancer-related inflammation
- (2008) Alberto Mantovani et al. NATURE
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started