Auto-induction of phase I and phase II metabolism of artemisinin in healthy Chinese subjects after oral administration of a new artemisinin-piperaquine fixed combination

Assessment of interaction potential of AZD2066 using in vitro metabolism tools, physiologically based pharmacokinetic modelling and in vivo cocktail data

(2013) Anna Nordmark et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

High-level semi-synthetic production of the potent antimalarial artemisinin

(2013) C. J. Paddon et al.   NATURE

Pharmacokinetic Comparison of Two Piperaquine-Containing Artemisinin Combination Therapies in Papua New Guinean Children with Uncomplicated Malaria

(2012) Sam Salman et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Rapid clinical induction of bupropion hydroxylation by metamizole in healthy Chinese men

(2012) Wen-Jie Qin et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Differential effects of clinically used derivatives and metabolites of artemisinin in the activation of constitutive androstane receptor isoforms

(2012) O Burk et al.   BRITISH JOURNAL OF PHARMACOLOGY

A Concise Synthesis of (+)-Artemisinin

(2012) Chunyin Zhu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Orally Formulated Artemisinin in Healthy Fasting Vietnamese Male Subjects: A Randomized, Four-Sequence, Open-Label, Pharmacokinetic Crossover Study

(2011) Tran Tinh Hien et al.   CLINICAL THERAPEUTICS

Rapid identification of phase I and II metabolites of artemisinin antimalarials using LTQ-Orbitrap hybrid mass spectrometer in combination with online hydrogen/deuterium exchange technique

(2011) Tian Liu et al.   JOURNAL OF MASS SPECTROMETRY

Effects of woohwangcheongsimwon suspension on the pharmacokinetics of bupropion and its active metabolite, 4-hydroxybupropion, in healthy subjects

(2010) Hyunmi Kim et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Effect of danshen extract on the activity of CYP3A4 in healthy volunteers

(2010) Furong Qiu et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Efficient assessment of the utility of immortalized Fa2N-4 cells for cytochrome P450 (CYP) induction studies using multiplex quantitative reverse transcriptase-polymerase chain reaction (qRT-PCR) and substrate cassette methodologies

(2008) J. R. Kenny et al.   XENOBIOTICA