The Naphthoquinone Diospyrin Is an Inhibitor of DNA Gyrase with a Novel Mechanism of Action

Mechanisms for Defining Supercoiling Set Point of DNA Gyrase Orthologs

(2012) Elsa M. Tretter et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The role of Ca 2+ in the activity of Mycobacterium tuberculosis DNA gyrase

(2012) Shantanu Karkare et al.   NUCLEIC ACIDS RESEARCH

Exploiting bacterial DNA gyrase as a drug target: current state and perspectives

(2011) Frédéric Collin et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Etoposide Quinone Is a Redox-Dependent Topoisomerase II Poison

(2011) David A. Jacob et al.   BIOCHEMISTRY

Mass Spectrometry Reveals That the Antibiotic Simocyclinone D8 Binds to DNA Gyrase in a “Bent-Over” Conformation: Evidence of Positive Cooperativity in Binding

(2011) Marcus J. Edwards et al.   BIOCHEMISTRY

Molecular mechanisms of antibiotic resistance

(2011) Gerard D. Wright   CHEMICAL COMMUNICATIONS

Inhibition of DNA gyrase and DNA topoisomerase IV of Staphylococcus aureus and Escherichia coli by aminocoumarin antibiotics

(2011) S. Alt et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Has the era of untreatable infections arrived?

(2009) D. M. Livermore   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

The Trypanocidal Activity of Naphthoquinones: A Review

(2009) Antônio Ventura Pinto et al.   MOLECULES

Crystal structure of DNA gyrase B′ domain sheds lights on the mechanism for T-segment navigation

(2009) Guangsen Fu et al.   NUCLEIC ACIDS RESEARCH

Crystal structure of the DNA gyrase GyrA N-terminal domain fromMycobacterium tuberculosis

(2009) Elsa M. Tretter et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

A Crystal Structure of the Bifunctional Antibiotic Simocyclinone D8, Bound to DNA Gyrase

(2009) M. J. Edwards et al.   SCIENCE

Confronting the scientific obstacles to global control of tuberculosis

(2008) Douglas B. Young et al.   JOURNAL OF CLINICAL INVESTIGATION