Enhanced Cytosolic Delivery and Release of CRISPR/Cas9 by Black Phosphorus Nanosheets for Genome Editing

Thermo-triggered Release of CRISPR-Cas9 System by Lipid-Encapsulated Gold Nanoparticles for Tumor Therapy

(2018) Peng Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A black phosphorus nanosheet-based siRNA delivery system for synergistic photothermal and gene therapy

(2018) Huimeng Wang et al.   CHEMICAL COMMUNICATIONS

Graphene oxide-mediated Cas9/sgRNA delivery for efficient genome editing

(2018) Huahua Yue et al.   Nanoscale

Endosomal Escape and Delivery of CRISPR/Cas9 Genome Editing Machinery Enabled by Nanoscale Zeolitic Imidazolate Framework

(2017) Shahad K. Alsaiari et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Two-dimensional black phosphorus: Synthesis, modification, properties, and applications

(2017) Ya Yi et al.   MATERIALS SCIENCE & ENGINEERING R-REPORTS

Nanoparticle delivery of Cas9 ribonucleoprotein and donor DNA in vivo induces homology-directed DNA repair

(2017) Kunwoo Lee et al.   Nature Biomedical Engineering

Light-Induced Ambient Degradation of Few-Layer Black Phosphorus: Mechanism and Protection

(2016) Qionghua Zhou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

High-fidelity CRISPR–Cas9 nucleases with no detectable genome-wide off-target effects

(2016) Benjamin P. Kleinstiver et al.   NATURE

Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9

(2016) John G Doench et al.   NATURE BIOTECHNOLOGY

Biodegradable black phosphorus-based nanospheres for in vivo photothermal cancer therapy

(2016) Jundong Shao et al.   Nature Communications

Ultrastrong Anchoring on the Periodic Atomic Grooves of Black Phosphorus

(2016) Dae Woo Kim et al.   Advanced Materials Interfaces

Tailoring non-viral delivery vehicles for transporting genome-editing tools

(2016) Wujin Sun et al.   Science China-Materials

Bioresponsive materials

(2016) Yue Lu et al.   Nature Reviews Materials

From Black Phosphorus to Phosphorene: Basic Solvent Exfoliation, Evolution of Raman Scattering, and Applications to Ultrafast Photonics

(2015) Zhinan Guo et al.   ADVANCED FUNCTIONAL MATERIALS

Self-Assembled DNA Nanoclews for the Efficient Delivery of CRISPR-Cas9 for Genome Editing

(2015) Wujin Sun et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ultrasmall Black Phosphorus Quantum Dots: Synthesis and Use as Photothermal Agents

(2015) Zhengbo Sun et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Revealing the importance of surface morphology of nanomaterials to biological responses: Adsorption of the villin headpiece onto graphene and phosphorene

(2015) Wei Zhang et al.   CARBON

Black Phosphorus: Narrow Gap, Wide Applications

(2015) Andres Castellanos-Gomez   Journal of Physical Chemistry Letters

Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex

(2015) Silvana Konermann et al.   NATURE

CASFISH: CRISPR/Cas9-mediated in situ labeling of genomic loci in fixed cells

(2015) Wulan Deng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rationally engineered Cas9 nucleases with improved specificity

(2015) I. M. Slaymaker et al.   SCIENCE

Efficient gene editing in adult mouse livers via adenoviral delivery of CRISPR/Cas9

(2014) Ranran Cheng et al.   FEBS LETTERS

Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing

(2014) Shengdar Q Tsai et al.   NATURE BIOTECHNOLOGY

Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype

(2014) Hao Yin et al.   NATURE BIOTECHNOLOGY

The new frontier of genome engineering with CRISPR-Cas9

(2014) J. A. Doudna et al.   SCIENCE

Chemical modifications and bioconjugate reactions of nanomaterials for sensing, imaging, drug delivery and therapy

(2013) Vasudevanpillai Biju   CHEMICAL SOCIETY REVIEWS

CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering

(2013) Prashant Mali et al.   NATURE BIOTECHNOLOGY

High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

(2013) Yanfang Fu et al.   NATURE BIOTECHNOLOGY

Graphene microsheets enter cells through spontaneous membrane penetration at edge asperities and corner sites

(2013) Y. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Strategies for the intracellular delivery of nanoparticles

(2010) Leo Y. T. Chou et al.   CHEMICAL SOCIETY REVIEWS

CRISPR/Cas, the Immune System of Bacteria and Archaea

(2010) P. Horvath et al.   SCIENCE

Biodegradable calcium phosphate nanoparticle with lipid coating for systemic siRNA delivery

(2009) Jun Li et al.   JOURNAL OF CONTROLLED RELEASE

Insertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCID-X1

(2008) Salima Hacein-Bey-Abina et al.   JOURNAL OF CLINICAL INVESTIGATION