Near-infrared optogenetic engineering of photothermal nanoCRISPR for programmable genome editing

Metabolizable Semiconducting Polymer Nanoparticles for Second Near-Infrared Photoacoustic Imaging

(2019) Yuyan Jiang et al.   ADVANCED MATERIALS

Precision control of CRISPR-Cas9 using small molecules and light

(2019) Soumyashree Ashok Gangopadhyay et al.   BIOCHEMISTRY

Material solutions for delivery of CRISPR/Cas-based genome editing tools: Current status and future outlook

(2019) Tao Wan et al.   Materials Today

Miniature gold nanorods for photoacoustic molecular imaging in the second near-infrared optical window

(2019) Yun-Sheng Chen et al.   Nature Nanotechnology

53BP1 nuclear bodies enforce replication timing at under-replicated DNA to limit heritable DNA damage

(2019) Julian Spies et al.   NATURE CELL BIOLOGY

Near‐Infrared‐II Molecular Dyes for Cancer Imaging and Surgery

(2019) Shoujun Zhu et al.   ADVANCED MATERIALS

Near-infrared upconversion–activated CRISPR-Cas9 system: A remote-controlled gene editing platform

(2019) Yongchun Pan et al.   Science Advances

Thermo-triggered Release of CRISPR-Cas9 System by Lipid-Encapsulated Gold Nanoparticles for Tumor Therapy

(2018) Peng Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

In Vitro and In Vivo Photothermal Cancer Therapeutic Effects of Gold Nanorods Modified with Mushroom β-Glucan

(2018) Xiaojie Li et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Cationic Polymer-Mediated CRISPR/Cas9 Plasmid Delivery for Genome Editing

(2018) Zhen Zhang et al.   MACROMOLECULAR RAPID COMMUNICATIONS

Simultaneous single-cell profiling of lineages and cell types in the vertebrate brain

(2018) Bushra Raj et al.   NATURE BIOTECHNOLOGY

Synthetic far-red light-mediated CRISPR-dCas9 device for inducing functional neuronal differentiation

(2018) Jiawei Shao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Near-infrared deep brain stimulation via upconversion nanoparticle–mediated optogenetics

(2018) Shuo Chen et al.   SCIENCE

CRISPR Correction of Duchenne Muscular Dystrophy

(2018) Yi-Li Min et al.   Annual Review of Medicine

Engineered anti-CRISPR proteins for optogenetic control of CRISPR–Cas9

(2018) Felix Bubeck et al.   NATURE METHODS

Temperature effect on CRISPR-Cas9 mediated genome editing

(2017) Guanghai Xiang et al.   Journal of Genetics and Genomics

Dual Quantification of MicroRNAs and Telomerase in Living Cells

(2017) Wei Ma et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Effect of wavelength and beam width on penetration in light-tissue interaction using computational methods

(2017) Caerwyn Ash et al.   LASERS IN MEDICAL SCIENCE

In vivo CRISPR screening identifies Ptpn2 as a cancer immunotherapy target

(2017) Robert T. Manguso et al.   NATURE

Optogenetic Immunomodulation: Shedding Light on Antitumor Immunity

(2017) Peng Tan et al.   TRENDS IN BIOTECHNOLOGY

Antiviral Goes Viral: Harnessing CRISPR/Cas9 to Combat Viruses in Humans

(2017) Jasper Adriaan Soppe et al.   TRENDS IN MICROBIOLOGY

Development of Light-Activated CRISPR Using Guide RNAs with Photocleavable Protectors

(2016) Piyush K. Jain et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Multidimensional chemical control of CRISPR–Cas9

(2016) Basudeb Maji et al.   Nature Chemical Biology

A chemical-inducible CRISPR–Cas9 system for rapid control of genome editing

(2016) Kaiwen Ivy Liu et al.   Nature Chemical Biology

Local triple-combination therapy results in tumour regression and prevents recurrence in a colon cancer model

(2016) João Conde et al.   NATURE MATERIALS

Pair correlation microscopy reveals the role of nanoparticle shape in intracellular transport and site of drug release

(2016) Elizabeth Hinde et al.   Nature Nanotechnology

An easy and efficient inducible CRISPR/Cas9 platform with improved specificity for multiple gene targeting

(2016) Jian Cao et al.   NUCLEIC ACIDS RESEARCH

Ligand-binding domains of nuclear receptors facilitate tight control of split CRISPR activity

(2016) Duy P. Nguyen et al.   Nature Communications

Optical Control of CRISPR/Cas9 Gene Editing

(2015) James Hemphill et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Inducible in vivo genome editing with CRISPR-Cas9

(2015) Lukas E Dow et al.   NATURE BIOTECHNOLOGY

A split-Cas9 architecture for inducible genome editing and transcription modulation

(2015) Bernd Zetsche et al.   NATURE BIOTECHNOLOGY

Photoactivatable CRISPR-Cas9 for optogenetic genome editing

(2015) Yuta Nihongaki et al.   NATURE BIOTECHNOLOGY

Small molecule–triggered Cas9 protein with improved genome-editing specificity

(2015) Kevin M Davis et al.   Nature Chemical Biology

A light-inducible CRISPR-Cas9 system for control of endogenous gene activation

(2015) Lauren R Polstein et al.   Nature Chemical Biology

In vivo delivery of transcription factors with multifunctional oligonucleotides

(2015) Kunwoo Lee et al.   NATURE MATERIALS

Therapeutic genome editing: prospects and challenges

(2015) David Benjamin Turitz Cox et al.   NATURE MEDICINE

High-throughput functional genomics using CRISPR–Cas9

(2015) Ophir Shalem et al.   NATURE REVIEWS GENETICS

Genome-wide inactivation of porcine endogenous retroviruses (PERVs)

(2015) L. Yang et al.   SCIENCE

Quantifying on- and off-target genome editing

(2015) Ayal Hendel et al.   TRENDS IN BIOTECHNOLOGY

An Inducible Lentiviral Guide RNA Platform Enables the Identification of Tumor-Essential Genes and Tumor-Promoting Mutations In Vivo

(2015) Brandon J. Aubrey et al.   Cell Reports

Cas-OFFinder: a fast and versatile algorithm that searches for potential off-target sites of Cas9 RNA-guided endonucleases

(2014) S. Bae et al.   BIOINFORMATICS

Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA

(2014) Hiroshi Nishimasu et al.   CELL

Somatic mosaicism and allele complexity induced by CRISPR/Cas9 RNA injections in mouse zygotes

(2014) Shuo-Ting Yen et al.   DEVELOPMENTAL BIOLOGY

Photothermic regulation of gene expression triggered by laser-induced carbon nanohorns

(2012) E. Miyako et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

(2012) M. Jinek et al.   SCIENCE