Bilobalide Enhances AMPK Activity to Improve Liver Injury and Metabolic Disorders in STZ-Induced Diabetes in Immature Rats via Regulating HMGB1/TLR4/NF-κB Signaling Pathway

The Underlying Mechanisms of Curcumin Inhibition of Hyperglycemia and Hyperlipidemia in Rats Fed a High-Fat Diet Combined With STZ Treatment

(2020) Zhen-Hong Xia et al.   MOLECULES

Macroencapsulated Human iPSC-Derived Pancreatic Progenitors Protect against STZ-Induced Hyperglycemia in Mice

(2019) Corinne Haller et al.   Stem Cell Reports

Targeting AMPK signaling pathway by natural products for treatment of diabetes mellitus and its complications

(2019) Tanuj Joshi et al.   JOURNAL OF CELLULAR PHYSIOLOGY

A new perspective on the biguanide, metformin therapy in type 2 diabetes and lactic acidosis

(2019) Nigishi Hotta   Journal of Diabetes Investigation

Bilobalide Suppresses Adipogenesis in 3T3-L1 Adipocytes via the AMPK Signaling Pathway

(2019) Su Bu et al.   MOLECULES

Definition, Classification and Diagnosis of Diabetes Mellitus

(2019) Astrid Petersmann et al.   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

Thiazolidinediones as antidiabetic agents: A critical review

(2018) M.J. Nanjan et al.   BIOORGANIC CHEMISTRY

Are physicians neglecting the risk of heart failure in diabetic patients who are receiving sulfonylureas? Lessons from the TOSCA.IT trial

(2018) Milton Packer   EUROPEAN JOURNAL OF HEART FAILURE

Effect of redox status of peripheral blood on immune signature of circulating regulatory and cytotoxic T cells in streptozotocin induced rodent model of type I diabetes

(2018) Kumari Anupam et al.   IMMUNOBIOLOGY

Baicalein improves liver inflammation in diabetic db/db mice by regulating HMGB1/TLR4/NF-κB signaling pathway

(2018) Huafeng Yin et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Early Effects of a Low Fat, Fructose-Rich Diet on Liver Metabolism, Insulin Signaling, and Oxidative Stress in Young and Adult Rats

(2018) Raffaella Crescenzo et al.   Frontiers in Physiology

Altered mitochondrial function in insulin-deficient and insulin-resistant states

(2018) Gregory N. Ruegsegger et al.   JOURNAL OF CLINICAL INVESTIGATION

Ginkgo biloba induces different gene expression signatures and oncogenic pathways in malignant and non-malignant cells of the liver

(2018) Carolin Czauderna et al.   PLoS One

Prolonged Ischemia Triggers Necrotic Depletion of Tissue-Resident Macrophages To Facilitate Inflammatory Immune Activation in Liver Ischemia Reperfusion Injury

(2017) Shi Yue et al.   JOURNAL OF IMMUNOLOGY

Global aetiology and epidemiology of type 2 diabetes mellitus and its complications

(2017) Yan Zheng et al.   Nature Reviews Endocrinology

Anthocyanin-rich mulberry fruit improves insulin resistance and protects hepatocytes against oxidative stress during hyperglycemia by regulating AMPK/ACC/mTOR pathway

(2017) Fujie Yan et al.   Journal of Functional Foods

Blocking of carnitine palmitoyl transferase 1 potently reduces stress-induced depression in rat highlighting a pivotal role of lipid metabolism

(2017) Anne Skøttrup Mørkholt et al.   Scientific Reports

Liver-Specific Activation of AMPK Prevents Steatosis on a High-Fructose Diet

(2017) Angela Woods et al.   Cell Reports

Ginkgolides and bilobalide protect BV2 microglia cells against OGD/reoxygenation injury by inhibiting TLR2/4 signaling pathways

(2016) Jian-Ming Zhou et al.   CELL STRESS & CHAPERONES

Aqueous extract from Aconitum carmichaelii Debeaux reduces liver injury in rats via regulation of HMGB1/TLR4/NF-ΚB/caspase-3 and PCNA signaling pathways

(2016) Jian-Xing Luo et al.   JOURNAL OF ETHNOPHARMACOLOGY

Changes in Oxidative Stress and Antioxidant Enzyme Activities in Streptozotocin-Induced Diabetes Mellitus in Rats: Role ofAlhagi maurorumExtracts

(2016) S. A. Sheweita et al.   Oxidative Medicine and Cellular Longevity

Hydroethanolic extract of Smallanthus sonchifolius leaves improves hyperglycemia of streptozotocin induced neonatal diabetic rats

(2016) Silmara Baroni et al.   Asian Pacific Journal of Tropical Medicine

The treatment of diabetes mellitus of patients with chronic liver disease

(2015) Diego García-Compeán et al.   Annals of Hepatology

Curcumin ameliorates streptozotocin-induced liver damage through modulation of endoplasmic reticulum stress-mediated apoptosis in diabetic rats

(2015) R. Afrin et al.   FREE RADICAL RESEARCH

Neuroprotective effects of bilobalide on cerebral ischemia and reperfusion injury are associated with inhibition of pro-inflammatory mediator production and down-regulation of JNK1/2 and p38 MAPK activation

(2014) Mingjin Jiang et al.   Journal of Neuroinflammation

AMPK Inhibition Blocks ROS-NFκB Signaling and Attenuates Endotoxemia-Induced Liver Injury

(2014) Yuan Guo et al.   PLoS One

Burden of Diabetes Mellitus Estimated with a Longitudinal Population-Based Study Using Administrative Databases

(2014) Luciana Scalone et al.   PLoS One

Causes of type 2 diabetes in China

(2014) Ronald Ching Wan Ma et al.   Lancet Diabetes & Endocrinology

The Effects of High-Dose Qinggan Huoxue Recipe on Acute Liver Failure Induced by D-Galactosamine in Rats

(2013) Hong Zhu et al.   Evidence-based Complementary and Alternative Medicine

HMGB1 Is a Therapeutic Target for Sterile Inflammation and Infection

(2011) Ulf Andersson et al.   Annual Review of Immunology

Immunosuppressive Effects of Streptozotocin-Induced Diabetes Result in Absolute Lymphopenia and a Relative Increase of T Regulatory Cells

(2011) Y. D. Muller et al.   DIABETES

Hyperglycemia induces apoptosis in rat liver through the increase of hydroxyl radical: new insights into the insulin effect

(2010) Daniel E Francés et al.   JOURNAL OF ENDOCRINOLOGY

White button mushroom (Agaricus bisporus) lowers blood glucose and cholesterol levels in diabetic and hypercholesterolemic rats

(2010) Sang Chul Jeong et al.   NUTRITION RESEARCH

Impaired immune responses in streptozotocin-induced type I diabetes in mice. Involvement of high glucose

(2008) R. Rubinstein et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Chronic Suppression of Acetyl-CoA Carboxylase 1 in β-Cells Impairs Insulin Secretion via Inhibition of Glucose Rather Than Lipid Metabolism

(2008) Sarah M. Ronnebaum et al.   JOURNAL OF BIOLOGICAL CHEMISTRY