Blocking of carnitine palmitoyl transferase 1 potently reduces stress-induced depression in rat highlighting a pivotal role of lipid metabolism

Brain membrane lipids in major depression and anxiety disorders

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The Carnitine Palmitoyl Transferase (CPT) System and Possible Relevance for Neuropsychiatric and Neurological Conditions

(2015) Ashraf Virmani et al.   MOLECULAR NEUROBIOLOGY

Integrating the monoamine, neurotrophin and cytokine hypotheses of depression — A central role for the serotonin transporter?

(2015) Jana Haase et al.   PHARMACOLOGY & THERAPEUTICS

A review of current evidence for acetyl-l-carnitine in the treatment of depression

(2014) Sheng-Min Wang et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Chronic mild stress for modeling anhedonia

(2013) Ove Wiborg   CELL AND TISSUE RESEARCH

Effect of Allium macrostemon on a rat model of depression studied by using plasma lipid and acylcarnitine profiles from liquid chromatography/mass spectrometry

(2013) Shili Chen et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Mitochondrial Dysfunction Induces Formation of Lipid Droplets as a Generalized Response to Stress

(2013) Seon-Jin Lee et al.   Oxidative Medicine and Cellular Longevity

L-acetylcarnitine causes rapid antidepressant effects through the epigenetic induction of mGlu2 receptors

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Pharmacogenomic predictors of citalopram treatment outcome in major depressive disorder

(2013) Firoza Mamdani et al.   WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY

The neurobiology of depression and antidepressant action

(2012) Paul Willner et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

CD4+CD25+ Regulatory T Cell Depletion Modulates Anxiety and Depression-Like Behaviors in Mice

(2012) Soo-Jeong Kim et al.   PLoS One

Carnitine Palmitoyltransferase (CPT) Modulators: A Medicinal Chemistry Perspective on 35 Years of Research

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The neurobiology of anhedonia and other reward-related deficits

(2011) Andre Der-Avakian et al.   TRENDS IN NEUROSCIENCES

Inhibition of fatty acid metabolism ameliorates disease activity in an animal model of multiple sclerosis

(2011) Leah P. Shriver et al.   Scientific Reports

Cannabinoid CB1 and Dopamine D1 Receptors Partnership in the Modulation of Emotional Neural Processing

(2011) Irit Akirav et al.   Frontiers in Behavioral Neuroscience

The Dopamine and Cannabinoid Interaction in the Modulation of Emotions and Cognition: Assessing the Role of Cannabinoid CB1 Receptor in Neurons Expressing Dopamine D1 Receptors

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Open questions in current models of antidepressant action

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A general introduction to the biochemistry of mitochondrial fatty acid β-oxidation

(2010) Sander Michel Houten et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Chronic social defeat stress disrupts regulation of lipid synthesis

(2010) Jen-Chieh Chuang et al.   JOURNAL OF LIPID RESEARCH

The engine driving the ship: metabolic steering of cell proliferation and death

(2010) Marisa R. Buchakjian et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Inflammation and Its Discontents: The Role of Cytokines in the Pathophysiology of Major Depression

(2009) Andrew H. Miller et al.   BIOLOGICAL PSYCHIATRY

A Meta-Analysis of Cytokines in Major Depression

(2009) Yekta Dowlati et al.   BIOLOGICAL PSYCHIATRY

Carnitine palmitoyltransferase IA polymorphism P479L is common in Greenland Inuit and is associated with elevated plasma apolipoprotein A-I

(2009) Chandheeb Rajakumar et al.   JOURNAL OF LIPID RESEARCH

Opposite effects of anandamide andn-arachidonoyl dopamine in the regulation of prostaglandin E2and 8-iso-PGF2αformation in primary glial cells

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Working towards an exegesis for lipids in biology

(2009) H Alex Brown et al.   Nature Chemical Biology

Brain arachidonic and docosahexaenoic acid cascades are selectively altered by drugs, diet and disease

(2008) Stanley I. Rapoport   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Anandamide and NADA bi-directionally modulate presynaptic Ca2+ levels and transmitter release in the hippocampus

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