Gasdermin E permits interleukin-1 beta release in distinct sublytic and pyroptotic phases
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Title
Gasdermin E permits interleukin-1 beta release in distinct sublytic and pyroptotic phases
Authors
Keywords
cell death, interleukin-1, IL-1, inflammasome, gasdermins, gasdermin E, GSDME, gasdermin D, GSDMD, pore-forming proteins
Journal
Cell Reports
Volume 35, Issue 2, Pages 108998
Publisher
Elsevier BV
Online
2021-04-15
DOI
10.1016/j.celrep.2021.108998
References
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Note: Only part of the references are listed.- Gasdermin E–mediated target cell pyroptosis by CAR T cells triggers cytokine release syndrome
- (2020) Yuying Liu et al. Science Immunology
- Osthole inhibits ovarian carcinoma cells through LC3-mediated autophagy and GSDME-dependent pyroptosis except for apoptosis
- (2020) Jing Liang et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation
- (2020) Jun Jacob Hu et al. NATURE IMMUNOLOGY
- GSDME-Dependent Incomplete Pyroptosis Permits Selective IL-1α Release under Caspase-1 Inhibition
- (2020) Emi Aizawa et al. iScience
- Caspase-1 cleaves Bid to release mitochondrial SMAC and drive secondary necrosis in the absence of GSDMD
- (2020) Rosalie Heilig et al. Life Science Alliance
- Cleavage of GSDME by caspase-3 determines lobaplatin-induced pyroptosis in colon cancer cells
- (2019) Junhui Yu et al. Cell Death & Disease
- Calpain drives pyroptotic vimentin cleavage, intermediate filament loss, and cell rupture that mediates immunostimulation
- (2019) Michael A. Davis et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Extrinsic and intrinsic apoptosis activate pannexin‐1 to drive NLRP3 inflammasome assembly
- (2019) Kaiwen W Chen et al. EMBO JOURNAL
- Crystal Structures of the Full-Length Murine and Human Gasdermin D Reveal Mechanisms of Autoinhibition, Lipid Binding, and Oligomerization
- (2019) Zhonghua Liu et al. IMMUNITY
- Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation
- (2019) Corey Rogers et al. Nature Communications
- ATP induces caspase-3/gasdermin E-mediated pyroptosis in NLRP3 pathway-blocked murine macrophages
- (2019) Chen-Ying Zeng et al. APOPTOSIS
- Caspase-1 initiates apoptosis in the absence of gasdermin D
- (2019) Kohsuke Tsuchiya et al. Nature Communications
- Pannexin‐1 promotes NLRP3 activation during apoptosis but is dispensable for canonical or noncanonical inflammasome activation
- (2019) Kaiwen W. Chen et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Dioscin inhibits the growth of human osteosarcoma by inducing G2/M‐phase arrest, apoptosis, and GSDME‐dependent cell death in vitro and in vivo
- (2019) Qiuyue Ding et al. JOURNAL OF CELLULAR PHYSIOLOGY
- DPP8/9 inhibitors are universal activators of functional NLRP1 alleles
- (2019) Kuo Gai et al. Cell Death & Disease
- Determination of the Potential Tumor-Suppressive Effects of Gsdme in a Chemically Induced and in a Genetically Modified Intestinal Cancer Mouse Model
- (2019) Lieselot Croes et al. Cancers
- Beyond inflammasomes: emerging function of gasdermins during apoptosis and NETosis
- (2019) Kaiwen W Chen et al. EMBO JOURNAL
- The Gasdermin-D pore acts as a conduit for IL-1β secretion in mice
- (2018) Rosalie Heilig et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- The Pore-Forming Protein Gasdermin D Regulates Interleukin-1 Secretion from Living Macrophages
- (2018) Charles L. Evavold et al. IMMUNITY
- Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity
- (2018) Dave Boucher et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Caspase-1 Is an Apical Caspase Leading to Caspase-3 Cleavage in the AIM2 Inflammasome Response, Independent of Caspase-8
- (2018) Vitaliya Sagulenko et al. JOURNAL OF MOLECULAR BIOLOGY
- DPP8/DPP9 inhibitor-induced pyroptosis for treatment of acute myeloid leukemia
- (2018) Darren C. Johnson et al. NATURE MEDICINE
- Cryo-EM structure of the gasdermin A3 membrane pore
- (2018) Jianbin Ruan et al. NATURE
- ASC- and caspase-8-dependent apoptotic pathway diverges from the NLRC4 inflammasome in macrophages
- (2018) Bettina L. Lee et al. Scientific Reports
- Interleukin-1β Maturation Triggers Its Relocation to the Plasma Membrane for Gasdermin-D-Dependent and -Independent Secretion
- (2018) Mercedes Monteleone et al. Cell Reports
- Caspase-8 induces cleavage of gasdermin D to elicit pyroptosis during Yersinia infection
- (2018) Joseph Sarhan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pathogen blockade of TAK1 triggers caspase-8–dependent cleavage of gasdermin D and cell death
- (2018) Pontus Orning et al. SCIENCE
- ESCRT-dependent membrane repair negatively regulates pyroptosis downstream of GSDMD activation
- (2018) Sebastian Rühl et al. SCIENCE
- Gasdermin E Does Not Limit Apoptotic Cell Disassembly by Promoting Early Onset of Secondary Necrosis in Jurkat T Cells and THP-1 Monocytes
- (2018) Rochelle Tixeira et al. Frontiers in Immunology
- Nucleotide-binding oligomerization domain (NOD) signaling defects and cell death susceptibility cannot be uncoupled in X-linked inhibitor of apoptosis (XIAP)-driven inflammatory disease
- (2017) Steven M. Chirieleison et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin
- (2017) Yupeng Wang et al. NATURE
- Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death
- (2017) Corey Rogers et al. Nature Communications
- The Inflammasome Drives GSDMD-Independent Secondary Pyroptosis and IL-1 Release in the Absence of Caspase-1 Protease Activity
- (2017) Katharina S. Schneider et al. Cell Reports
- Systematic comparison of 2A peptides for cloning multi-genes in a polycistronic vector
- (2017) Ziqing Liu et al. Scientific Reports
- GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death
- (2016) Lorenzo Sborgi et al. EMBO JOURNAL
- Active Caspase-1 Induces Plasma Membrane Pores That Precede Pyroptotic Lysis and Are Blocked by Lanthanides
- (2016) Hana M. Russo et al. JOURNAL OF IMMUNOLOGY
- Pore-forming activity and structural autoinhibition of the gasdermin family
- (2016) Jingjin Ding et al. NATURE
- Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores
- (2016) Xing Liu et al. NATURE
- DPP8 and DPP9 inhibition induces pro-caspase-1-dependent monocyte and macrophage pyroptosis
- (2016) Marian C Okondo et al. Nature Chemical Biology
- GsdmD p30 elicited by caspase-11 during pyroptosis forms pores in membranes
- (2016) Robin A. Aglietti et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion
- (2015) Wan-ting He et al. CELL RESEARCH
- Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling
- (2015) Nobuhiko Kayagaki et al. NATURE
- Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
- (2015) Jianjin Shi et al. NATURE
- Cryo-EM structure of the activated NAIP2-NLRC4 inflammasome reveals nucleated polymerization
- (2015) L. Zhang et al. SCIENCE
- AIM2 and NLRP3 inflammasomes activate both apoptotic and pyroptotic death pathways via ASC
- (2013) V Sagulenko et al. CELL DEATH AND DIFFERENTIATION
- Cytoplasmic LPS Activates Caspase-11: Implications in TLR4-Independent Endotoxic Shock
- (2013) J. A. Hagar et al. SCIENCE
- Noncanonical Inflammasome Activation by Intracellular LPS Independent of TLR4
- (2013) N. Kayagaki et al. SCIENCE
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