Dioscin inhibits the growth of human osteosarcoma by inducing G2/M‐phase arrest, apoptosis, and GSDME‐dependent cell death in vitro and in vivo
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Dioscin inhibits the growth of human osteosarcoma by inducing G2/M‐phase arrest, apoptosis, and GSDME‐dependent cell death in vitro and in vivo
Authors
Keywords
-
Journal
JOURNAL OF CELLULAR PHYSIOLOGY
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2019-09-19
DOI
10.1002/jcp.29197
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Cleavage of GSDME by caspase-3 determines lobaplatin-induced pyroptosis in colon cancer cells
- (2019) Junhui Yu et al. Cell Death & Disease
- Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation
- (2019) Corey Rogers et al. Nature Communications
- Tetrandrine and cepharanthine induce apoptosis through caspase cascade regulation, cell cycle arrest, MAPK activation and PI3K/Akt/mTOR signal modification in glucocorticoid resistant human leukemia Jurkat T cells
- (2019) Wencheng Xu et al. CHEMICO-BIOLOGICAL INTERACTIONS
- GSDME mediates caspase-3-dependent pyroptosis in gastric cancer
- (2018) Yubin Wang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Connexin 43 upregulation by dioscin inhibits melanoma progression via suppressing malignancy and inducing M1 polarization
- (2017) Yu Kou et al. INTERNATIONAL JOURNAL OF CANCER
- Natural compounds targeting major cell signaling pathways: a novel paradigm for osteosarcoma therapy
- (2017) Pablo Angulo et al. Journal of Hematology & Oncology
- Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin
- (2017) Yupeng Wang et al. NATURE
- MAPK signalling pathway in cancers: Olive products as cancer preventive and therapeutic agents
- (2017) Ilaria Peluso et al. SEMINARS IN CANCER BIOLOGY
- Dioscin induces prostate cancer cell apoptosis through activation of estrogen receptor-β
- (2017) Xufeng Tao et al. Cell Death & Disease
- Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death
- (2017) Corey Rogers et al. Nature Communications
- Ki67, PCNA, and MCM proteins: Markers of proliferation in the diagnosis of breast cancer
- (2016) Miroslava Juríková et al. ACTA HISTOCHEMICA
- Dioscin suppresses human laryngeal cancer cells growth via induction of cell-cycle arrest and MAPK-mediated mitochondrial-derived apoptosis and inhibition of tumor invasion
- (2016) Lingling Si et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- miR-15b modulates multidrug resistance in human osteosarcomain vitroandin vivo
- (2016) Zhenfeng Duan et al. Molecular Oncology
- Dioscin Induces Apoptosis in Human Cervical Carcinoma HeLa and SiHa Cells through ROS-Mediated DNA Damage and the Mitochondrial Signaling Pathway
- (2016) Xinwei Zhao et al. MOLECULES
- Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores
- (2016) Xing Liu et al. NATURE
- Dioscin reduces ovariectomy-induced bone loss by enhancing osteoblastogenesis and inhibiting osteoclastogenesis
- (2016) Xufeng Tao et al. PHARMACOLOGICAL RESEARCH
- Dioscin suppresses hepatocellular carcinoma tumor growth by inducing apoptosis and regulation of TP53, BAX, BCL2 and cleaved CASP3
- (2016) Guangxian Zhang et al. PHYTOMEDICINE
- Gasdermin D: the long-awaited executioner of pyroptosis
- (2015) Si Ming Man et al. CELL RESEARCH
- Dioscin ameliorates cerebral ischemia/reperfusion injury through the downregulation of TLR4 signaling via HMGB-1 inhibition
- (2015) Xufeng Tao et al. FREE RADICAL BIOLOGY AND MEDICINE
- Long noncoding RNA MALAT1 as a potential therapeutic target in osteosarcoma
- (2015) Xianyi Cai et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
- (2015) Jianjin Shi et al. NATURE
- Erratum: Traditional Chinese medication for cardiovascular disease
- (2015) Pan-Pan Hao et al. Nature Reviews Cardiology
- Dioscin induces caspase-independent apoptosis through activation of apoptosis-inducing factor in breast cancer cells
- (2014) Eun-Ae Kim et al. APOPTOSIS
- Recent advances in osteosarcoma
- (2014) Sander M Botter et al. CURRENT OPINION IN PHARMACOLOGY
- Targeting Apoptosis Pathways for New Cancer Therapeutics
- (2013) Longchuan Bai et al. Annual Review of Medicine
- Dioscin-induced autophagy mitigates cell apoptosis through modulation of PI3K/Akt and ERK and JNK signaling pathways in human lung cancer cell lines
- (2013) Ming-Ju Hsieh et al. ARCHIVES OF TOXICOLOGY
- p38 and JNK MAPK pathways control the balance of apoptosis and autophagy in response to chemotherapeutic agents
- (2013) Xinbing Sui et al. CANCER LETTERS
- The ATM protein kinase: regulating the cellular response to genotoxic stress and more
- (2013) Yosef Shiloh et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Mitochondria: gatekeepers of response to chemotherapy
- (2013) Kristopher A. Sarosiek et al. TRENDS IN CELL BIOLOGY
- Pharmacological tools for the development of traditional Chinese medicine
- (2013) Xuan Liu et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Dioscin, a natural steroid saponin, shows remarkable protective effect against acetaminophen-induced liver damage in vitro and in vivo
- (2012) Xiaoming Zhao et al. TOXICOLOGY LETTERS
- TMEM14A inhibits N-(4-hydroxyphenyl)retinamide-induced apoptosis through the stabilization of mitochondrial membrane potential
- (2011) Im Sun Woo et al. CANCER LETTERS
- The DFNA5 gene, responsible for hearing loss and involved in cancer, encodes a novel apoptosis-inducing protein
- (2011) Ken Op de Beeck et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Activation of c-Jun N-terminal kinase is essential for mitochondrial membrane potential change and apoptosis induced by doxycycline in melanoma cells
- (2010) Jiunn-Min Shieh et al. BRITISH JOURNAL OF PHARMACOLOGY
- Targeting apoptosis pathways in cancer by Chinese medicine
- (2010) Min Li-Weber CANCER LETTERS
- Osteosarcoma incidence and survival rates from 1973 to 2004
- (2009) Lisa Mirabello et al. CANCER
- Aberrant promoter methylation and tumor suppressive activity of the DFNA5 gene in colorectal carcinoma
- (2008) M S Kim et al. ONCOGENE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started