Determination of the Potential Tumor-Suppressive Effects of Gsdme in a Chemically Induced and in a Genetically Modified Intestinal Cancer Mouse Model

Cleavage of GSDME by caspase-3 determines lobaplatin-induced pyroptosis in colon cancer cells

(2019) Junhui Yu et al.   Cell Death & Disease

Chemotherapeutic paclitaxel and cisplatin differentially induce pyroptosis in A549 lung cancer cells via caspase-3/GSDME activation

(2019) Cheng-cheng Zhang et al.   APOPTOSIS

Methylation analysis of Gasdermin E shows great promise as a biomarker for colorectal cancer

(2019) Joe Ibrahim et al.   Cancer Medicine

GSDME mediates caspase-3-dependent pyroptosis in gastric cancer

(2018) Yubin Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Large-scale analysis of DFNA5 methylation reveals its potential as biomarker for breast cancer

(2018) Lieselot Croes et al.   Clinical Epigenetics

Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin

(2017) Yupeng Wang et al.   NATURE

Pulling the apoptotic trigger for necrosis

(2017) Paulina Strzyz   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death

(2017) Corey Rogers et al.   Nature Communications

DFNA5 promoter methylation a marker for breast tumorigenesis

(2017) Lieselot Croes et al.   Oncotarget

Pro-necrotic molecules impact local immunosurveillance in human breast cancer

(2017) Gautier Stoll et al.   OncoImmunology

Nonproliferative and Proliferative Lesions ofthe Gastrointestinal Tract, Pancreas andSalivary Glands of the Rat and Mouse

(2016) Thomas Nolte et al.   Journal of Toxicologic Pathology

The deafness gene DFNA5 induces programmed cell death through mitochondria and MAPK-related pathways

(2015) Sofie Van Rossom et al.   Frontiers in Cellular Neuroscience

DFNA5, a Gene Involved in Hearing Loss and Cancer: A Review

(2014) Ken Op de Beeck et al.   ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY

Sex disparity in colonic adenomagenesis involves promotion by male hormones, not protection by female hormones

(2014) James M. Amos-Landgraf et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The expression and regulation of DFNA5 in human hepatocellular carcinoma DFNA5 in hepatocellular carcinoma

(2013) Cong-Jun Wang et al.   MOLECULAR BIOLOGY REPORTS

Rodent Intestinal Epithelial Carcinogenesis

(2013) Jerrold M. Ward et al.   TOXICOLOGIC PATHOLOGY

Modeling Colitis-Associated Cancer with Azoxymethane (AOM) and Dextran Sulfate Sodium (DSS)

(2012) Ameet I. Thaker et al.   Jove-Journal of Visualized Experiments

The splicing mutant of the human tumor suppressor protein DFNA5 induces programmed cell death when expressed in the yeast Saccharomyces cerevisiae

(2012) Sofie Van Rossom et al.   Frontiers in Oncology

The DFNA5 gene, responsible for hearing loss and involved in cancer, encodes a novel apoptosis-inducing protein

(2011) Ken Op de Beeck et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Genomic screening for genes upregulated by demethylation revealed novel targets of epigenetic silencing in breast cancer

(2009) Tomoko Fujikane et al.   BREAST CANCER RESEARCH AND TREATMENT

Methylation of the DFNA5 increases risk of lymph node metastasis in human breast cancer

(2008) Myoung Sook Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mouse models for the study of colon carcinogenesis

(2008) D. W. Rosenberg et al.   CARCINOGENESIS

Aberrant promoter methylation and tumor suppressive activity of the DFNA5 gene in colorectal carcinoma

(2008) M S Kim et al.   ONCOGENE