Ferulic Acid Ameliorates Alzheimer’s Disease-like Pathology and Repairs Cognitive Decline by Preventing Capillary Hypofunction in APP/PS1 Mice

3K3A-activated protein C blocks amyloidogenic BACE1 pathway and improves functional outcome in mice

(2019) Divna Lazic et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A critical appraisal of amyloid-β-targeting therapies for Alzheimer disease

(2019) Francesco Panza et al.   Nature Reviews Neurology

Neutrophil adhesion in brain capillaries reduces cortical blood flow and impairs memory function in Alzheimer’s disease mouse models

(2019) Jean C. Cruz Hernández et al.   NATURE NEUROSCIENCE

Amyloid β oligomers constrict human capillaries in Alzheimer’s disease via signaling to pericytes

(2019) Ross Nortley et al.   SCIENCE

High-resolution mapping of brain vasculature and its impairment in the hippocampus of Alzheimer's disease mice

(2019) Xiaochuan Zhang et al.   National Science Review

Alzheimer Disease: An Update on Pathobiology and Treatment Strategies

(2019) Justin M. Long et al.   CELL

Design, synthesis, and biological evaluation of ferulic acid based 1,3,4-oxadiazole hybrids as multifunctional therapeutics for the treatment of Alzheimer’s disease

(2019) Avanish Tripathi et al.   BIOORGANIC CHEMISTRY

Capillary cerebral amyloid angiopathy in Alzheimer’s disease: association with allocortical/hippocampal microinfarcts and cognitive decline

(2018) Moritz Hecht et al.   ACTA NEUROPATHOLOGICA

NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease

(2018) Clifford R. Jack et al.   Alzheimers & Dementia

Dysregulation of the epigenetic landscape of normal aging in Alzheimer’s disease

(2018) Raffaella Nativio et al.   NATURE NEUROSCIENCE

SWISS-MODEL: homology modelling of protein structures and complexes

(2018) Andrew Waterhouse et al.   NUCLEIC ACIDS RESEARCH

Cerebrovascular Alterations in Alzheimer Disease

(2018) Costantino Iadecola et al.   CIRCULATION RESEARCH

Effects of Hypoperfusion in Alzheimer's Disease

(2018) Benjamin P. Austin et al.   JOURNAL OF ALZHEIMERS DISEASE

Primary Cerebral Blood Flow Deficiency and Alzheimer's Disease: Shadows and Lights

(2018) Marianna Mazza et al.   JOURNAL OF ALZHEIMERS DISEASE

Combined treatment with the phenolics (−)-epigallocatechin-3-gallate and ferulic acid improves cognition and reduces Alzheimer-like pathology in mice

(2018) Takashi Mori et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reduced Cardiovascular Functions in Patients with Alzheimer’s Disease

(2017) Wang-Sheng Jin et al.   JOURNAL OF ALZHEIMERS DISEASE

A systemic view of Alzheimer disease — insights from amyloid-β metabolism beyond the brain

(2017) Jun Wang et al.   Nature Reviews Neurology

Cerebral blood flow regulation and neurovascular dysfunction in Alzheimer disease

(2017) Kassandra Kisler et al.   NATURE REVIEWS NEUROSCIENCE

The interhemispheric CA1 circuit governs rapid generalisation but not fear memory

(2017) Heng Zhou et al.   Nature Communications

Alzheimer’s Disease: From Genetic Variants to the Distinct Pathological Mechanisms

(2017) Qiying Sun et al.   Frontiers in Molecular Neuroscience

The Cellular Phase of Alzheimer’s Disease

(2016) Bart De Strooper et al.   CELL

The amyloid hypothesis of Alzheimer's disease at 25 years

(2016) Dennis J Selkoe et al.   EMBO Molecular Medicine

Protective effects of a dimeric derivative of ferulic acid in animal models of Alzheimer's disease

(2016) Jun-Sub Jung et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Memory retrieval by activating engram cells in mouse models of early Alzheimer’s disease

(2016) Dheeraj S. Roy et al.   NATURE

Transcript-level expression analysis of RNA-seq experiments with HISAT, StringTie and Ballgown

(2016) Mihaela Pertea et al.   Nature Protocols

Inhibition of Rac1 activity in the hippocampus impaired extinction of contextual fear

(2016) Lizhu Jiang et al.   NEUROPHARMACOLOGY

Early role of vascular dysregulation on late-onset Alzheimer’s disease based on multifactorial data-driven analysis

(2016) Y. Iturria-Medina et al.   Nature Communications

Cerebrovascular disease in ageing and Alzheimer’s disease

(2015) Seth Love et al.   ACTA NEUROPATHOLOGICA

Iterative Vessel Segmentation of Fundus Images

(2015) Sohini Roychowdhury et al.   IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING

Brain endothelial TAK1 and NEMO safeguard the neurovascular unit

(2015) Dirk A. Ridder et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Whole-scale neurobehavioral assessments of photothrombotic ischemia in freely moving mice

(2015) Cheng-Long Yu et al.   JOURNAL OF NEUROSCIENCE METHODS

StringTie enables improved reconstruction of a transcriptome from RNA-seq reads

(2015) Mihaela Pertea et al.   NATURE BIOTECHNOLOGY

Ballgown bridges the gap between transcriptome assembly and expression analysis

(2015) Alyssa C Frazee et al.   NATURE BIOTECHNOLOGY

HISAT: a fast spliced aligner with low memory requirements

(2015) Daehwan Kim et al.   NATURE METHODS

GLUT1 reductions exacerbate Alzheimer's disease vasculo-neuronal dysfunction and degeneration

(2015) Ethan A Winkler et al.   NATURE NEUROSCIENCE

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(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

Synaptic P-Rex1 signaling regulates hippocampal long-term depression and autism-like social behavior

(2015) Jun Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ferulic Acid: A Hope for Alzheimer’s Disease Therapy from Plants

(2015) Antonella Sgarbossa et al.   Nutrients

Skewer: a fast and accurate adapter trimmer for next-generation sequencing paired-end reads

(2014) Hongshan Jiang et al.   BMC BIOINFORMATICS

Blood–brain-barriers in aging and in Alzheimer’s disease

(2013) Fernanda Marques et al.   Molecular Neurodegeneration

Ferulic Acid Is a Nutraceutical β-Secretase Modulator That Improves Behavioral Impairment and Alzheimer-like Pathology in Transgenic Mice

(2013) Takashi Mori et al.   PLoS One

Neurovascular Dysfunction and Faulty Amyloid  -Peptide Clearance in Alzheimer Disease

(2013) A. P. Sagare et al.   Cold Spring Harbor Perspectives in Medicine

The Neuropsychological Profile of Alzheimer Disease

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Protective Effects of Ferulic Acid in Amyloid Precursor Protein Plus Presenilin-1 Transgenic Mouse Model of Alzheimer Disease

(2012) Ji-Jing Yan et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Alzheimer Mechanisms and Therapeutic Strategies

(2012) Yadong Huang et al.   CELL

A multimodal RAGE-specific inhibitor reduces amyloid β–mediated brain disorder in a mouse model of Alzheimer disease

(2012) Rashid Deane et al.   JOURNAL OF CLINICAL INVESTIGATION

Correlation of Alzheimer Disease Neuropathologic Changes With Cognitive Status: A Review of the Literature

(2012) Peter T. Nelson et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Pre-clinical models of human cerebral small vessel disease: Utility for clinical application

(2012) Atticus H. Hainsworth et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

The vascular factor in Alzheimer's disease: A study in Golgi technique and electron microscopy

(2012) Stavros J. Baloyannis et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

The capillary dysfunction hypothesis of Alzheimer's disease

(2012) Leif Østergaard et al.   NEUROBIOLOGY OF AGING

Laser Speckle Contrast Imaging of Cerebral Blood Flow

(2011) Andrew K. Dunn   ANNALS OF BIOMEDICAL ENGINEERING

HHblits: lightning-fast iterative protein sequence searching by HMM-HMM alignment

(2011) Michael Remmert et al.   NATURE METHODS

Ensembl BioMarts: a hub for data retrieval across taxonomic space

(2011) R. J. Kinsella et al.   Database-The Journal of Biological Databases and Curation

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(2010) Francesca Mangialasche et al.   LANCET NEUROLOGY

Soluble amyloid-β, effect on cerebral arteriolar regulation and vascular cells

(2010) Hans H Dietrich et al.   Molecular Neurodegeneration

Classification and basic pathology of Alzheimer disease

(2009) Charles Duyckaerts et al.   ACTA NEUROPATHOLOGICA

Phenolic Compounds Prevent Alzheimer’s Pathology through Different Effects on the Amyloid-β Aggregation Pathway

(2009) Tsuyoshi Hamaguchi et al.   AMERICAN JOURNAL OF PATHOLOGY

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

BLAST+: architecture and applications

(2009) Christiam Camacho et al.   BMC BIOINFORMATICS

Pathological role of hypoxia in Alzheimer's disease

(2009) Xin Zhang et al.   EXPERIMENTAL NEUROLOGY

Antistress Effect of TRPV1 Channel on Synaptic Plasticity and Spatial Memory

(2008) Hong-Bin Li et al.   BIOLOGICAL PSYCHIATRY