Ferulic Acid: A Hope for Alzheimer’s Disease Therapy from Plants

Key factors which concur to the correct therapeutic evaluation of herbal products in free radical-induced diseases

(2015) Cesare Mancuso   Frontiers in Pharmacology

Toxicity of Protein Oligomers Is Rationalized by a Function Combining Size and Surface Hydrophobicity

(2014) Benedetta Mannini et al.   ACS Chemical Biology

Mediterranean Diet And Longevity: An Example Of Nutraceuticals?

(2014) Sonya Vasto et al.   Current Vascular Pharmacology

Mediterranean Diet and Healthy Ageing: A Sicilian Perspective

(2014) Sonya Vasto et al.   GERONTOLOGY

Amyloid Aggregation: Role of Biological Membranes and the Aggregate–Membrane System

(2014) Monica Bucciantini et al.   Journal of Physical Chemistry Letters

Enzymatic Production of Ferulic Acid from Defatted Rice Bran by Using a Combination of Bacterial Enzymes

(2013) Misugi Uraji et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

The effects of ferulic acid on β-amyloid fibrillar structures investigated through experimental and computational techniques

(2013) Antonella Sgarbossa et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Neuroprotective ferulic acid (FA)–glycol chitosan (GC) nanoparticles for functional restoration of traumatically injured spinal cord

(2013) Wei Wu et al.   BIOMATERIALS

Trans-ferulic acid-based solid lipid nanoparticles and their antioxidant effect in rat brain microsomes

(2013) Sonia Trombino et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Ferulic acid: Pharmacological and toxicological aspects

(2013) Cesare Mancuso et al.   FOOD AND CHEMICAL TOXICOLOGY

Noise-Induced Hearing Loss (NIHL) as a Target of Oxidative Stress-Mediated Damage: Cochlear and Cortical Responses after an Increase in Antioxidant Defense

(2013) A. R. Fetoni et al.   JOURNAL OF NEUROSCIENCE

β-Amyloid Amorphous Aggregates Induced by the Small Natural Molecule Ferulic Acid

(2013) Emilia Bramanti et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Ferulic Acid Is a Nutraceutical β-Secretase Modulator That Improves Behavioral Impairment and Alzheimer-like Pathology in Transgenic Mice

(2013) Takashi Mori et al.   PLoS One

Protective Effects of Ferulic Acid in Amyloid Precursor Protein Plus Presenilin-1 Transgenic Mouse Model of Alzheimer Disease

(2012) Ji-Jing Yan et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Are oxidative stress and mitochondrial dysfunction the key players in the neurodegenerative diseases?

(2012) Marta Di Carlo et al.   FREE RADICAL RESEARCH

Natural Biomolecules and Protein Aggregation: Emerging Strategies against Amyloidogenesis

(2012) Antonella Sgarbossa   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Phenolic Compounds Prevent Amyloid β-Protein Oligomerization and Synaptic Dysfunction by Site-specific Binding

(2012) Kenjiro Ono et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipophilic Caffeic and Ferulic Acid Derivatives Presenting Cytotoxicity against Human Breast Cancer Cells

(2011) Teresa L. Serafim et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Pharmacologists and Alzheimer disease therapy: to boldly go where no scientist has gone before

(2011) Cesare Mancuso et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Toxic effects of amyloid fibrils on cell membranes: the importance of ganglioside GM1

(2011) Monica Bucciantini et al.   FASEB JOURNAL

Effect of Phenolic Compounds Against Aβ Aggregation and Aβ-Induced Toxicity in Transgenic C. elegans

(2011) Seema Jagota et al.   NEUROCHEMICAL RESEARCH

Ferulic acid prevents the cerebral ischemic injury-induced decrease of Akt and Bad phosphorylation

(2011) Phil-Ok Koh   NEUROSCIENCE LETTERS

Ferulic acid inhibits nitric oxide-induced apoptosis by enhancing GABAB1 receptor expression in transient focal cerebral ischemia in rats

(2010) Chin-yi Cheng et al.   ACTA PHARMACOLOGICA SINICA

REVIEW: Curcumin and Alzheimer's Disease

(2010) Tsuyoshi Hamaguchi et al.   CNS Neuroscience & Therapeutics

Effects of hypericin on the structure and aggregation properties of β-amyloid peptides

(2010) Emilia Bramanti et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Lignin Biosynthesis and Structure

(2010) R. Vanholme et al.   PLANT PHYSIOLOGY

Phenolic Compounds Prevent Alzheimer’s Pathology through Different Effects on the Amyloid-β Aggregation Pathway

(2009) Tsuyoshi Hamaguchi et al.   AMERICAN JOURNAL OF PATHOLOGY

Aβ Oligomers and Fibrillar Aggregates Induce Different Apoptotic Pathways in LAN5 Neuroblastoma Cell Cultures

(2009) Pasquale Picone et al.   BIOPHYSICAL JOURNAL

Ferulic Acid-Loaded Lipid Nanostructures as Drug Delivery Systems for Alzheimers Disease: Preparation, Characterization and Cytotoxicity Studies

(2009) M. Bondi et al.   Current Nanoscience

Ferulic acid inhibits oxidative stress and cell death induced by Ab oligomers: Improved delivery by solid lipid nanoparticles

(2009) Pasquale Picone et al.   FREE RADICAL RESEARCH

Ferulic acid induces neural progenitor cell proliferation in vitro and in vivo

(2009) T. Yabe et al.   NEUROSCIENCE

Oxidative stress increases levels of endogenous amyloid-β peptides secreted from primary chick brain neurons

(2008) Claire Goldsbury et al.   AGING CELL

Fitting Neurological Protein Aggregation Kinetic Data via a 2-Step, Minimal/“Ockham's Razor” Model:  The Finke−Watzky Mechanism of Nucleation Followed by Autocatalytic Surface Growth†

(2008) Aimee M. Morris et al.   BIOCHEMISTRY

Ferulic acid and its therapeutic potential as a hormetin for age-related diseases

(2008) Eugenio Barone et al.   BIOGERONTOLOGY

Ferulic acid provides neuroprotection against oxidative stress-related apoptosis after cerebral ischemia/reperfusion injury by inhibiting ICAM-1 mRNA expression in rats

(2008) Chin-Yi Cheng et al.   BRAIN RESEARCH

Redox regulation of cellular stress response by ferulic acid ethyl ester in human dermal fibroblasts: role of vitagenes

(2008) Vittorio Calabrese et al.   CLINICS IN DERMATOLOGY

In vitroperturbation of aggregation processes in β-amyloid peptides: A spectroscopic study

(2008) Antonella Sgarbossa et al.   FEBS LETTERS

In vitro and in vivo antioxidant properties of ferulic acid: A comparative study with other natural oxidation inhibitors

(2008) S ITAGAKI et al.   FOOD CHEMISTRY

Novel Effects of a Single Administration of Ferulic Acid on the Regulation of Blood Pressure and the Hepatic Lipid Metabolic Profile in Stroke-Prone Spontaneously Hypertensive Rats

(2008) Ardiansyah et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY