Mitochondrial Dysfunction and Mitophagy Closely Cooperate in Neurological Deficits Associated with Alzheimer’s Disease and Type 2 Diabetes

miR‐181a negatively modulates synaptic plasticity in hippocampal cultures and its inhibition rescues memory deficits in a mouse model of Alzheimer’s disease

(2020) Carlos J. Rodriguez‐Ortiz et al.   AGING CELL

Liraglutide Protects Against Brain Amyloid-β1–42 Accumulation in Female Mice with Early Alzheimer’s Disease-Like Pathology by Partially Rescuing Oxidative/Nitrosative Stress and Inflammation

(2020) Ana I. Duarte et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Role of Dietary Antioxidants in the Pathogenesis of Neurodegenerative Diseases and Their Impact on Cerebral Oxidoreductive Balance

(2020) Anna Winiarska-Mieczan et al.   Nutrients

Long-Lasting Exendin-4 Fusion Protein Improves Memory Deficits in High-Fat Diet/Streptozotocin-Induced Diabetic Mice

(2020) Kyung-Ah Park et al.   Pharmaceutics

The protective effect of metformin on mitochondrial dysfunction and endoplasmic reticulum stress in diabetic mice brain

(2020) Taskeen Fathima Docrat et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The Regulation of microRNAs in Alzheimer's Disease

(2020) Xianjuan Kou et al.   Frontiers in Neurology

Mitochondrial MicroRNAs in Aging and Neurodegenerative Diseases

(2020) Albin John et al.   Cells

Mitophagy: An Emerging Role in Aging and Age-Associated Diseases

(2020) Guo Chen et al.   Frontiers in Cell and Developmental Biology

Circulating mitochondrial DNA: New indices of type 2 diabetes-related cognitive impairment in Mexican Americans

(2019) Talisa Silzer et al.   PLoS One

Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer’s disease

(2019) Evandro F. Fang et al.   NATURE NEUROSCIENCE

Deficiency of Mitophagy Receptor FUNDC1 Impairs Mitochondrial Quality and Aggravates Dietary-Induced Obesity and Metabolic Syndrome

(2019) Hao Wu et al.   Autophagy

BDNF-mediated mitophagy alleviates high-glucose-induced brain microvascular endothelial cell injury

(2019) Hong Jin et al.   APOPTOSIS

Mitochondrial dysfunction in Alzheimer's disease: Role in pathogenesis and novel therapeutic opportunities

(2019) Judit M. Perez Ortiz et al.   BRITISH JOURNAL OF PHARMACOLOGY

Amyloid Beta and Phosphorylated Tau-Induced Defective Autophagy and Mitophagy in Alzheimer’s Disease

(2019) P. Hemachandra Reddy et al.   Cells

Altered Mitochondrial Network Morphology and Regulatory Proteins in Mitochondrial Quality Control in Myotubes from Severely Obese Humans With or Without Type 2 Diabetes

(2019) Anders E. Gundersen et al.   Applied Physiology Nutrition and Metabolism

Dynamic of mitochondrial network, cristae, and mitochondrial nucleoids in pancreatic β-cells

(2019) Petr Ježek et al.   MITOCHONDRION

Prevalence, Influence Factors and Cognitive Characteristics of Mild Cognitive Impairment in Type 2 Diabetes Mellitus

(2019) Wei Li et al.   Frontiers in Aging Neuroscience

Relationship Between Oxidative Stress, ER Stress, and Inflammation in Type 2 Diabetes: The Battle Continues

(2019) Burgos-Morón et al.   Journal of Clinical Medicine

The Mitochondrial Antioxidant SS-31 Modulates Oxidative Stress, Endoplasmic Reticulum Stress, and Autophagy in Type 2 Diabetes

(2019) Irene Escribano-López et al.   Journal of Clinical Medicine

Dynamics of Dynamin-Related Protein 1 in Alzheimer’s Disease and Other Neurodegenerative Diseases

(2019) Darryll Oliver et al.   Cells

Over-expression of miR-34a induces rapid cognitive impairment and Alzheimer’s disease-like pathology

(2019) S. Sarkar et al.   BRAIN RESEARCH

Age-related hyperinsulinemia leads to insulin resistance in neurons and cell-cycle-induced senescence

(2019) Hei-Man Chow et al.   NATURE NEUROSCIENCE

Metformin Improves Mitochondrial Respiratory Activity through Activation of AMPK

(2019) Yu Wang et al.   Cell Reports

Dysfunctional Mitochondria and Mitophagy as Drivers of Alzheimer’s Disease Pathogenesis

(2019) Anushka Chakravorty et al.   Frontiers in Aging Neuroscience

Transcriptomic and Network Analysis Highlight the Association of Diabetes at Different Stages of Alzheimer’s Disease

(2019) Jose A. Santiago et al.   Frontiers in Neuroscience

Antioxidant Therapies for Neuroprotection-A Review

(2019) Teleanu et al.   Journal of Clinical Medicine

MicroRNA-34a (miR-34a) Mediates Retinal Endothelial Cell Premature Senescence through Mitochondrial Dysfunction and Loss of Antioxidant Activities

(2019) Menaka C. Thounaojam et al.   Antioxidants

Autophagy and mitophagy biomarkers are reduced in sera of patients with Alzheimer’s disease and mild cognitive impairment

(2019) Massimiliano Castellazzi et al.   Scientific Reports

Effect of Metformin on Mitochondrial Pathways in Human Skeletal Muscle Cells

(2018) JESSICA SACKS et al.   DIABETES

Post-treatment with the GLP-1 analogue liraglutide alleviate chronic inflammation and mitochondrial stress induced by Status epilepticus

(2018) Rui-Fang Wang et al.   EPILEPSY RESEARCH

Mitochondrial dynamics: overview of molecular mechanisms

(2018) Lisa Tilokani et al.   Essays in Biochemistry

Sweet Mitochondria: A Shortcut to Alzheimer’s Disease

(2018) Paula I. Moreira   JOURNAL OF ALZHEIMERS DISEASE

Mitochondrial dynamics in adaptive and maladaptive cellular stress responses

(2018) Verónica Eisner et al.   NATURE CELL BIOLOGY

Connecting Alzheimer's disease to diabetes: Underlying mechanisms and potential therapeutic targets

(2018) Marcelo N.N. Vieira et al.   NEUROPHARMACOLOGY

Pancreatic β cells overexpressing hIAPP impaired mitophagy and unbalanced mitochondrial dynamics

(2018) Miriam García Hernández et al.   Cell Death & Disease

SIRT1, miR-132 and miR-212 link human longevity to Alzheimer’s Disease

(2018) A. Hadar et al.   Scientific Reports

Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy

(2018) Gian-Luca McLelland et al.   eLife

MicroRNA-146a: A Comprehensive Indicator of Inflammation and Oxidative Stress Status Induced in the Brain of Chronic T2DM Rats

(2018) Yangmei Xie et al.   Frontiers in Pharmacology

Diverse Roles of Mitochondria in Immune Responses: Novel Insights Into Immuno-Metabolism

(2018) Anusha Angajala et al.   Frontiers in Immunology

Mitochondrial Dynamics in Type 2 Diabetes and Cancer

(2018) Michelle Williams et al.   Frontiers in Endocrinology

Alzheimer's disease and Type 2 Diabetes mellitus are distinct diseases with potential overlapping metabolic dysfunction upstream of observed cognitive decline

(2018) Yevgen Chornenkyy et al.   BRAIN PATHOLOGY

Pathogenesis of Alzheimer's Disease: Role of Amyloid-beta and Hyperphosphorylated Tau Protein

(2018) Rabia Sajjad et al.   INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES

Incidence of Dementia is Increased in Type 2 Diabetes and Reduced by the Use of Sulfonylureas and Metformin

(2018) Chih-Cheng Hsu et al.   JOURNAL OF ALZHEIMERS DISEASE

Alzheimer's Disease and Diabetes: An Integrative View of the Role of Mitochondria, Oxidative Stress, and Insulin

(2018) Paula I. Moreira   JOURNAL OF ALZHEIMERS DISEASE

Type 2 Diabetic and Alzheimer's Disease Mice Present Similar Behavioral, Cognitive, and Vascular Anomalies

(2018) Cristina Carvalho et al.   JOURNAL OF ALZHEIMERS DISEASE

Neuroprotective Effects of Amylin Analogues on Alzheimer’s Disease Pathogenesis and Cognition

(2018) John Grizzanti et al.   JOURNAL OF ALZHEIMERS DISEASE

Lixisenatide enhances mitochondrial biogenesis and function through regulating the CREB/PGC-1α pathway

(2018) Zhen Zhao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Evolving and Expanding the Roles of Mitophagy as a Homeostatic and Pathogenic Process

(2018) Åsa B. Gustafsson et al.   PHYSIOLOGICAL REVIEWS

Oxidative Stress, Synaptic Dysfunction, and Alzheimer’s Disease

(2017) Eric Tönnies et al.   JOURNAL OF ALZHEIMERS DISEASE

Mitochondrial dynamics in neuronal injury, development and plasticity

(2017) Kyle H. Flippo et al.   JOURNAL OF CELL SCIENCE

Dementia-like pathology in type-2 diabetes: A novel microRNA mechanism

(2017) Anuradha Kalani et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Correcting miR92a-vGAT-Mediated GABAergic Dysfunctions Rescues Human Tau-Induced Anxiety in Mice

(2017) Xiaoguang Li et al.   MOLECULAR THERAPY

MicroRNA-125b promotes neurons cell apoptosis and Tau phosphorylation in Alzheimer’s disease

(2017) Xiaohui Ma et al.   NEUROSCIENCE LETTERS

Mitophagy and Alzheimer’s Disease: Cellular and Molecular Mechanisms

(2017) Jesse S. Kerr et al.   TRENDS IN NEUROSCIENCES

miR‑34a and miR‑125b are upregulated in peripheral blood mononuclear cells from patients with type 2 diabetes mellitus

(2017) Yanxin Shen et al.   Experimental and Therapeutic Medicine

MicroRNA-126 inhibits cell viability and invasion in a diabetic retinopathy model via targeting IRS-1

(2017) Shifeng Fang et al.   Oncology Letters

Upregulation of miR-181a impairs hepatic glucose and lipid homeostasis

(2017) Xiliang Du et al.   Oncotarget

Reduced Gray Matter Volume in Patients with Type 2 Diabetes Mellitus

(2017) Jia Liu et al.   Frontiers in Aging Neuroscience

Mitochondrial dynamics in type 2 diabetes: Pathophysiological implications

(2017) Susana Rovira-Llopis et al.   Redox Biology

Alterations in Mitochondrial Oxidative Stress and Mitophagy in Subjects with Prediabetes and Type 2 Diabetes Mellitus

(2017) Shipra Bhansali et al.   Frontiers in Endocrinology

Mitochondria-Targeted Antioxidants Protect Against Amyloid-β Toxicity in Alzheimer's Disease Neurons

(2017) Maria Manczak et al.   JOURNAL OF ALZHEIMERS DISEASE

A Multi-Center Randomized Proof-of-Concept Clinical Trial Applying [18F]FDG-PET for Evaluation of Metabolic Therapy with Rosiglitazone XR in Mild to Moderate Alzheimer's Disease

(2017) Sofia Tzimopoulou et al.   JOURNAL OF ALZHEIMERS DISEASE

Methylene blue inhibits NLRP3, NLRC4, AIM2, and non-canonical inflammasome activation

(2017) Huijeong Ahn et al.   Scientific Reports

Liraglutide restores chronic ER stress, autophagy impairments and apoptotic signalling in SH-SY5Y cells

(2017) Theodora Panagaki et al.   Scientific Reports

EFFECTS OF THE INSULIN SENSITIZER METFORMIN ON ALZHEIMER'S DISEASE BIOMARKERS: RESULTS OF A BRIEF CROSSOVER PILOT STUDY

(2016) Aaron M. Koenig   Alzheimers & Dementia

The prevalence of mild cognitive impairment with type 2 diabetes mellitus among elderly people in China: A cross-sectional study

(2016) Yuxia Gao et al.   ARCHIVES OF GERONTOLOGY AND GERIATRICS

Expression of microRNA-34a in Alzheimer's disease brain targets genes linked to synaptic plasticity, energy metabolism, and resting state network activity

(2016) S. Sarkar et al.   BRAIN RESEARCH

Evidence for Mitochondrial UPR Gene Activation in Familial and Sporadic Alzheimer's Disease

(2016) John S. Beck et al.   Current Alzheimer Research

miR-302 Attenuates Amyloid-β-Induced Neurotoxicity through Activation of Akt Signaling

(2016) Hsin-Hua Li et al.   JOURNAL OF ALZHEIMERS DISEASE

MiR-155 Enhances Insulin Sensitivity by Coordinated Regulation of Multiple Genes in Mice

(2016) Xiaolin Lin et al.   PLoS Genetics

Mitochondrial Dysfunction in Alzheimer’s Disease and the Rationale for Bioenergetics Based Therapies

(2016) Isaac G. Onyango et al.   Aging and Disease

miRNA expression profiles in cerebrospinal fluid and blood of patients with Alzheimer’s disease and other types of dementia – an exploratory study

(2016) Sofie Sølvsten Sørensen et al.   Translational Neurodegeneration

Restoring Mitochondrial Function: A Small Molecule-mediated Approach to Enhance Glucose Stimulated Insulin Secretion in Cholesterol Accumulated Pancreatic beta cells

(2016) Suman Asalla et al.   Scientific Reports

Alzheimer's disease and type 2 diabetes-related alterations in brain mitochondria, autophagy and synaptic markers

(2015) Cristina Carvalho et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Prevalence and prognosis of Alzheimer’s disease at the mild cognitive impairment stage

(2015) Stephanie J. B. Vos et al.   BRAIN

Increased Oxidative Stress and Mitochondrial Dysfunction in Zucker Diabetic Rat Liver and Brain

(2015) Haider Raza et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Defects in mitophagy promote redox-driven metabolic syndrome in the absence of TP53INP1

(2015) M. Seillier et al.   EMBO Molecular Medicine

Protective effects of exercise in metabolic disorders are mediated by inhibition of mitochondrial-derived sterile inflammation

(2015) Maghsoud Peeri et al.   MEDICAL HYPOTHESES

Shared genetic etiology underlying Alzheimer's disease and type 2 diabetes

(2015) Ke Hao et al.   MOLECULAR ASPECTS OF MEDICINE

Mechanisms of Mitochondrial Dysfunction in Alzheimer’s Disease

(2015) Chris Cadonic et al.   MOLECULAR NEUROBIOLOGY

Dysregulation of parkin in the substantia nigra of db/db and high-fat diet mice

(2015) R. Khang et al.   NEUROSCIENCE

Defining roles of PARKIN and ubiquitin phosphorylation by PINK1 in mitochondrial quality control using a ubiquitin replacement strategy

(2015) Alban Ordureau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Avocado Oil Improves Mitochondrial Function and Decreases Oxidative Stress in Brain of Diabetic Rats

(2015) Omar Ortiz-Avila et al.   Journal of Diabetes Research

Evidence for a neuroprotective microRNA pathway in amnestic mild cognitive impairment

(2015) Rebecca B. Weinberg et al.   Frontiers in Neuroscience

Type 2 diabetes mellitus

(2015) Ralph A. DeFronzo et al.   Nature Reviews Disease Primers

Choline dehydrogenase interacts with SQSTM1/p62 to recruit LC3 and stimulate mitophagy

(2014) Sungwoo Park et al.   Autophagy

Deterioration of plasticity and metabolic homeostasis in the brain of the UCD-T2DM rat model of naturally occurring type-2 diabetes

(2014) Rahul Agrawal et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

A Meta-Analysis of Cognitive Functioning in Nondemented Adults with Type 2 Diabetes Mellitus

(2014) Michelle C.E. Monette et al.   Canadian Journal of Diabetes

Receptor-mediated mitophagy in yeast and mammalian systems

(2014) Lei Liu et al.   CELL RESEARCH

Alzheimer’s Disease and Type 2 Diabetes: Multiple Mechanisms Contribute to Interactions

(2014) Anusha Jayaraman et al.   Current Diabetes Reports

Drp1-Mediated Mitochondrial Abnormalities Link to Synaptic Injury in Diabetes Model

(2014) Shengbin Huang et al.   DIABETES

Greater muscle protein synthesis and mitochondrial biogenesis in males compared with females during sprint interval training

(2014) Rebecca L. Scalzo et al.   FASEB JOURNAL

Mitochondrial quality control systems sustain brain mitochondrial bioenergetics in early stages of type 2 diabetes

(2014) R. X. Santos et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

MiR-126 Regulates Growth Factor Activities and Vulnerability to Toxic Insult in Neurons

(2014) Woori Kim et al.   MOLECULAR NEUROBIOLOGY

Flavonoid, morin inhibits oxidative stress, inflammation and enhances neurotrophic support in the brain of streptozotocin-induced diabetic rats

(2014) Mohammad S. Ola et al.   NEUROLOGICAL SCIENCES

Micro spies from the brain to the periphery: new clues from studies on microRNAs in neuropsychiatric disorders

(2014) Elisabetta Maffioletti et al.   Frontiers in Cellular Neuroscience

Defective mitophagy driven by dysregulation of rheb and KIF5B contributes to mitochondrial reactive oxygen species (ROS)-induced nod-like receptor 3 (NLRP3) dependent proinflammatory response and aggravates lipotoxicity

(2014) Sijun Yang et al.   Redox Biology

Restless legs syndrome in patients with type 2 diabetes: effectiveness of pramipexole therapy

(2014) Shin-Ichi Harashima et al.   BMJ Supportive & Palliative Care

After the banquet

(2013) Jianhui Zhu et al.   Autophagy

Crosstalk between diabetes and brain: Glucagon-like peptide-1 mimetics as a promising therapy against neurodegeneration

(2013) A.I. Duarte et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Brain Atrophy in Type 2 Diabetes: Regional distribution and influence on cognition

(2013) C. Moran et al.   DIABETES CARE

Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fission

(2013) Oliver C. Losón et al.   MOLECULAR BIOLOGY OF THE CELL

Neuroprotective effects of the amylin analogue pramlintide on Alzheimer's disease pathogenesis and cognition

(2013) Brittany L. Adler et al.   NEUROBIOLOGY OF AGING

Mitochondrial Dynamics — Mitochondrial Fission and Fusion in Human Diseases

(2013) Stephen L. Archer   NEW ENGLAND JOURNAL OF MEDICINE

Altered baseline brain activity in type 2 diabetes: A resting-state fMRI study

(2013) Wenqing Xia et al.   PSYCHONEUROENDOCRINOLOGY

A Small Molecule Promotes Mitochondrial Fusion in Mammalian Cells

(2012) Danling Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mitophagy: mechanisms, pathophysiological roles, and analysis

(2012) Wen-Xing Ding et al.   BIOLOGICAL CHEMISTRY

Inhibition of Drp1 provides neuroprotection in vitro and in vivo

(2012) J Grohm et al.   CELL DEATH AND DIFFERENTIATION

Alzheimer’s Disease And Type 2 Diabetes: Exploring The Association To Obesity And Tyrosine Hydroxylase

(2012) Medha Priyadarshini et al.   CNS & Neurological Disorders-Drug Targets

Metabolic Alterations Induced by Sucrose Intake and Alzheimer’s Disease Promote Similar Brain Mitochondrial Abnormalities

(2012) Cristina Carvalho et al.   DIABETES

Loss of mitochondrial protease OMA1 alters processing of the GTPase OPA1 and causes obesity and defective thermogenesis in mice

(2012) Pedro M Quirós et al.   EMBO JOURNAL

Adult mice maintained on a high-fat diet exhibit object location memory deficits and reduced hippocampal SIRT1 gene expression

(2012) Frankie D. Heyward et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Caffeine Consumption Prevents Diabetes-Induced Memory Impairment and Synaptotoxicity in the Hippocampus of NONcZNO10/LTJ Mice

(2012) João M. N. Duarte et al.   PLoS One

Mitofusin 2 (Mfn2) links mitochondrial and endoplasmic reticulum function with insulin signaling and is essential for normal glucose homeostasis

(2012) D. Sebastian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The diagnosis of mild cognitive impairment due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Marilyn S. Albert et al.   Alzheimers & Dementia

Amyloid beta impairs mitochondrial anterograde transport and degenerates synapses in Alzheimer's disease neurons

(2011) Marcus J. Calkins et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage

(2011) Maria Manczak et al.   HUMAN MOLECULAR GENETICS

MicroRNAs and Type 2 Diabetes/Obesity

(2011) Mustafa Abdo Saif Dehwah et al.   Journal of Genetics and Genomics

Impaired mitochondrial biogenesis contributes to mitochondrial dysfunction in Alzheimer’s disease

(2011) Baiyang Sheng et al.   JOURNAL OF NEUROCHEMISTRY

Anti-Tumor Activity of a Novel Compound-CDF Is Mediated by Regulating miR-21, miR-200, and PTEN in Pancreatic Cancer

(2011) Bin Bao et al.   PLoS One

Differential Glucose-Regulation of MicroRNAs in Pancreatic Islets of Non-Obese Type 2 Diabetes Model Goto-Kakizaki Rat

(2011) Jonathan Lou S. Esguerra et al.   PLoS One

Mitochondrial biogenesis and fission in axons in cell culture and animal models of diabetic neuropathy

(2010) Andrea M. Vincent et al.   ACTA NEUROPATHOLOGICA

The Interplay Between Mitochondrial Dynamics and Mitophagy

(2010) Gilad Twig et al.   ANTIOXIDANTS & REDOX SIGNALING

Cortical and hippocampal mitochondria bioenergetics and oxidative status during hyperglycemia and/or insulin-induced hypoglycemia

(2010) Susana Cardoso et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Type 2 Diabetes and Cognitive Decline in Middle-Aged Men and Women: The Doetinchem Cohort Study

(2010) A. C. J. Nooyens et al.   DIABETES CARE

MicroRNA-15a positively regulates insulin synthesis by inhibiting uncoupling protein-2 expression

(2010) Liang-Liang Sun et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Genetic ablation of Dicer in adult forebrain neurons results in abnormal tau hyperphosphorylation and neurodegeneration

(2010) Sébastien S. Hébert et al.   HUMAN MOLECULAR GENETICS

Mitochondrial fusion and fission in cell life and death

(2010) Benedikt Westermann   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Targeting mitochondrial biogenesis for preventing and treating insulin resistance in diabetes and obesity: Hope from natural mitochondrial nutrients☆

(2009) Jiankang Liu et al.   ADVANCED DRUG DELIVERY REVIEWS

Dynamic regulation of PGC-1α localization and turnover implicates mitochondrial adaptation in calorie restriction and the stress response

(2009) Rozalyn M. Anderson et al.   AGING CELL

Oxidative Stress and Neurodegenerative Diseases: A Review of Upstream and Downstream Antioxidant Therapeutic Options

(2009) Bayani Uttara et al.   Current Neuropharmacology

Diabetes regulates mitochondrial biogenesis and fission in mouse neurons

(2009) J. L. Edwards et al.   DIABETOLOGIA

Impaired Balance of Mitochondrial Fission and Fusion in Alzheimer's Disease

(2009) X. Wang et al.   JOURNAL OF NEUROSCIENCE

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

(2009) Carles Cantó et al.   NATURE

Efficacy of PPAR-γ agonist pioglitazone in mild Alzheimer disease

(2009) Tomohiko Sato et al.   NEUROBIOLOGY OF AGING

Diabetes and the Risk of Multi-System Aging Phenotypes: A Systematic Review and Meta-Analysis

(2009) Feng-Ping Lu et al.   PLoS One

Mitochondrial dynamics as a bridge between mitochondrial dysfunction and insulin resistance

(2009) Antonio Zorzano et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

Dynamin-Like Protein 1 Reduction Underlies Mitochondrial Morphology and Distribution Abnormalities in Fibroblasts from Sporadic Alzheimer's Disease Patients

(2008) Xinglong Wang et al.   AMERICAN JOURNAL OF PATHOLOGY

Mitochondrial fission mediates high glucose-induced cell death through elevated production of reactive oxygen species

(2008) Tianzheng Yu et al.   CARDIOVASCULAR RESEARCH

Chemical Inhibition of the Mitochondrial Division Dynamin Reveals Its Role in Bax/Bak-Dependent Mitochondrial Outer Membrane Permeabilization

(2008) Ann Cassidy-Stone et al.   DEVELOPMENTAL CELL

Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

(2008) Gilad Twig et al.   EMBO JOURNAL

Conditional Loss of Dicer Disrupts Cellular and Tissue Morphogenesis in the Cortex and Hippocampus

(2008) T. H. Davis et al.   JOURNAL OF NEUROSCIENCE

Mitochondrial dysfunction: An early event in Alzheimer pathology accumulates with age in AD transgenic mice

(2008) S. Hauptmann et al.   NEUROBIOLOGY OF AGING

Mitochondrial Ca2+ Overload Underlies Aβ Oligomers Neurotoxicity Providing an Unexpected Mechanism of Neuroprotection by NSAIDs

(2008) Sara Sanz-Blasco et al.   PLoS One

Dicer loss in striatal neurons produces behavioral and neuroanatomical phenotypes in the absence of neurodegeneration

(2008) T. L. Cuellar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deadenylation is a widespread effect of miRNA regulation

(2008) A. Eulalio et al.   RNA