Antioxidant Therapies for Neuroprotection-A Review

In vitro studies of the neuroprotective activities of astaxanthin and fucoxanthin against amyloid beta (Aβ1-42) toxicity and aggregation

(2019) Mousa Alghazwi et al.   NEUROCHEMISTRY INTERNATIONAL

Anti-Inflammatory Effect of Lycopene on Experimental Spinal Cord Ischemia Injury via Cyclooxygenase-2 Suppression

(2019) Ye  Hua et al.   NEUROIMMUNOMODULATION

Evaluating Dose- and Time-Dependent Effects of Vitamin C Treatment on a Parkinson’s Disease Fly Model

(2019) Huynh Man Anh et al.   Parkinsons Disease

Neuronanomedicine: An Up-to-Date Overview

(2019) Daniel Mihai Teleanu et al.   Pharmaceutics

Nanomaterials for Drug Delivery to the Central Nervous System

(2019) Daniel Teleanu et al.   Nanomaterials

Astaxanthin Ameliorates Lipopolysaccharide-Induced Neuroinflammation, Oxidative Stress and Memory Dysfunction through Inactivation of the Signal Transducer and Activator of Transcription 3 Pathway

(2019) Ji Han et al.   Marine Drugs

Lopinavir-NO, a nitric oxide-releasing HIV protease inhibitor, suppresses the growth of melanoma cells in vitro and in vivo

(2019) Svetlana Paskas et al.   INVESTIGATIONAL NEW DRUGS

The Effectiveness of Vitamin E Treatment in Alzheimer’s Disease

(2019) Ana Lloret et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Neuroprotective effect of astaxanthin on newborn rats exposed to prenatal maternal seizures

(2019) Yan Lu et al.   BRAIN RESEARCH BULLETIN

Elucidating the inhibitory potential of Vitamin A against fibrillation and amyloid associated cytotoxicity

(2019) Parvez Alam et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Mitochondrial electron transport chain, ROS generation and uncoupling (Review)

(2019) Ru‑Zhou Zhao et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Lycopene attenuates aluminum-induced hippocampal lesions by inhibiting oxidative stress-mediated inflammation and apoptosis in the rat

(2019) Zheng Cao et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Prophylactic neuroprotective propensity of Crocin, a carotenoid against rotenone induced neurotoxicity in mice: behavioural and biochemical evidence

(2019) Sriranjini Venkata Rao et al.   METABOLIC BRAIN DISEASE

Regulation of Toll-Like Receptor (TLR) Signaling Pathway by Polyphenols in the Treatment of Age-Linked Neurodegenerative Diseases: Focus on TLR4 Signaling

(2019) Shofiul Azam et al.   Frontiers in Immunology

Nitric oxide and hepatocellular cancer

(2019) Ronghua Wang et al.   BRITISH JOURNAL OF PHARMACOLOGY

Medicinal prospects of antioxidants: A review

(2019) Kumari Neha et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

The sour side of vitamin C might mediate neuroprotective, anticonvulsive and antidepressant-like effects

(2019) Udo Bonnet   MEDICAL HYPOTHESES

Endogenous non-enzymatic antioxidants in the human body

(2018) Iwona Mirończuk-Chodakowska et al.   Advances in Medical Sciences

Nrf2 Pathway in Age-Related Neurological Disorders: Insights into MicroRNAs

(2018) Simona Paladino et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Nitric oxide donors for prostate and bladder cancers: Current state and challenges

(2018) Amedea B. Seabra et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Oxidative stress in autoimmune rheumatic diseases

(2018) Miranda J. Smallwood et al.   FREE RADICAL BIOLOGY AND MEDICINE

Protective role of β-carotene against oxidative stress and neuroinflammation in a rat model of spinal cord injury

(2018) Lihui Zhou et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The flavonoid, 2′-methoxy-6-methylflavone, affords neuroprotection following focal cerebral ischaemia

(2018) Andrew N Clarkson et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Phenolic compounds, antioxidant capacity and physicochemical properties of Brazilian Apis mellifera honeys

(2018) Kelly Souza do Nascimento et al.   LWT-FOOD SCIENCE AND TECHNOLOGY

Activation of Nrf2 Pathway Contributes to Neuroprotection by the Dietary Flavonoid Tiliroside

(2018) Ravikanth Velagapudi et al.   MOLECULAR NEUROBIOLOGY

Oxidative stress, aging, and diseases

(2018) Ilaria Liguori et al.   Clinical Interventions in Aging

Neuroprotective Effects of Proanthocyanidins, Natural Flavonoids Derived From Plants, on Rotenone-Induced Oxidative Stress and Apoptotic Cell Death in Human Neuroblastoma SH-SY5Y Cells

(2018) Jian Ma et al.   Frontiers in Neuroscience

Neuroprotection through flavonoid: Enhancement of the glyoxalase pathway

(2018) Joel R. Frandsen et al.   Redox Biology

Bioactive flavonoids in medicinal plants: Structure, activity and biological fate

(2018) Tian-yang Wang et al.   Asian Journal of Pharmaceutical Sciences

Neuroprotective effect of crocin on substantia nigra in MPTP-induced Parkinson’s disease model of mice

(2018) Parisa Haeri et al.   ANATOMICAL SCIENCE INTERNATIONAL

Flavonoids and its Neuroprotective Effects on Brain Ischemia and Neurodegenerative Diseases

(2018) Manish Putteeraj et al.   CURRENT DRUG TARGETS

Anticancer and Differentiation Properties of the Nitric Oxide Derivative of Lopinavir in Human Glioblastoma Cells

(2018) Maria Basile et al.   MOLECULES

Vitamin C alleviates LPS-induced cognitive impairment in mice by suppressing neuroinflammation and oxidative stress

(2018) Xiao-Ying Zhang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Investigation of the neuroprotective effects of crocin via antioxidant activities in HT22 cells and in mice with Alzheimer's disease

(2018) Chunyue Wang et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

The Role of NADPH Oxidases and Oxidative Stress in Neurodegenerative Disorders

(2018) Anuradha Tarafdar et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The H2S Donor GYY4137 Stimulates Reactive Oxygen Species Generation in BV2 Cells While Suppressing the Secretion of TNF and Nitric Oxide

(2018) Milica Lazarević et al.   MOLECULES

Neuroprotective Natural Molecules, From Food to Brain

(2018) Joaquin González-Fuentes et al.   Frontiers in Neuroscience

Neuroprotective role of astaxanthin in hippocampal insulin resistance induced by Aβ peptides in animal model of Alzheimer’s disease

(2018) Syed Obaidur Rahman et al.   BIOMEDICINE & PHARMACOTHERAPY

Vitamin E: Emerging aspects and new directions

(2017) Francesco Galli et al.   FREE RADICAL BIOLOGY AND MEDICINE

Reactive oxygen species and cancer paradox: To promote or to suppress?

(2017) Sehamuddin Galadari et al.   FREE RADICAL BIOLOGY AND MEDICINE

Role of Vitamin E in the Treatment of Alzheimer’s Disease: Evidence from Animal Models

(2017) Agnese Gugliandolo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Oxidative Stress, Synaptic Dysfunction, and Alzheimer’s Disease

(2017) Eric Tönnies et al.   JOURNAL OF ALZHEIMERS DISEASE

Phenolic acid derivatives with neuroprotective effect from the aqueous extract of Clerodendranthus spicatus

(2017) Hai-Chun Zhou et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

Neuroprotective Effects of Antioxidants in the Management of Neurodegenerative Disorders: A Literature Review

(2017) Yunes Panahi et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Vitamin C prevents hypothyroidism associated neuronal damage in the hippocampus of neonatal and juvenile rats: A stereological study

(2017) Elnaz Khordad et al.   JOURNAL OF CHEMICAL NEUROANATOMY

A radical shift in perspective: mitochondria as regulators of reactive oxygen species

(2017) Daniel Munro et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Neuroprotective effect of total flavonoids from Ilex pubescens against focal cerebral ischemia/reperfusion injury in rats

(2017) Xiaoyan Fang et al.   Molecular Medicine Reports

Food, polyphenols and neuroprotection

(2017) Lea Pogačnik et al.   Neural Regeneration Research

Role of oxidative stress and antioxidants in daily nutrition and human health

(2017) Geir Bjørklund et al.   NUTRITION

Oxidative Stress: Harms and Benefits for Human Health

(2017) Gabriele Pizzino et al.   Oxidative Medicine and Cellular Longevity

Oxidative Stress in Neurodegenerative Diseases: From Molecular Mechanisms to Clinical Applications

(2017) Zewen Liu et al.   Oxidative Medicine and Cellular Longevity

NOX4-dependent neuronal autotoxicity and BBB breakdown explain the superior sensitivity of the brain to ischemic damage

(2017) Ana I. Casas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Isolation and identification of flavonoids from anticancer and neuroprotective extracts of Trigonella foenum graecum

(2017) Shabina Ishtiaq Ahmed et al.   TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH

Antioxidants: Friend or foe?

(2017) R. Sarangarajan et al.   Asian Pacific Journal of Tropical Medicine

The Neuroprotective Effects of Phenolic Acids: Molecular Mechanism of Action

(2017) et al.   Nutrients

Association of Antioxidant Supplement Use and Dementia in the Prevention of Alzheimer’s Disease by Vitamin E and Selenium Trial (PREADViSE)

(2017) Richard J. Kryscio et al.   JAMA Neurology

Use of Vitamin E and C Supplements for the Prevention of Cognitive Decline

(2016) Luta Luse Basambombo et al.   ANNALS OF PHARMACOTHERAPY

Rosmarinic acid prevents against memory deficits in ischemic mice

(2016) Analu Aragão Fonteles et al.   BEHAVIOURAL BRAIN RESEARCH

Protein oxidation and peroxidation

(2016) M. J. Davies   BIOCHEMICAL JOURNAL

Molecular mechanisms of ROS production and oxidative stress in diabetes

(2016) P. Newsholme et al.   BIOCHEMICAL JOURNAL

Adaptive regulation of the brain’s antioxidant defences by neurons and astrocytes

(2016) Paul S. Baxter et al.   FREE RADICAL BIOLOGY AND MEDICINE

Functional role of mitochondrial reactive oxygen species in physiology

(2016) Plamena R. Angelova et al.   FREE RADICAL BIOLOGY AND MEDICINE

Neuroprotective Effects of Bioavailable Polyphenol-Derived Metabolites against Oxidative Stress-Induced Cytotoxicity in Human Neuroblastoma SH-SY5Y Cells

(2016) Antonio González-Sarrías et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Antioxidant Activity/Capacity Measurement. 1. Classification, Physicochemical Principles, Mechanisms, and Electron Transfer (ET)-Based Assays

(2016) Reşat Apak et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Oxidative stress and metabolic disorders: Pathogenesis and therapeutic strategies

(2016) Vibha Rani et al.   LIFE SCIENCES

L-Ascorbate Protects Against Methamphetamine-Induced Neurotoxicity of Cortical Cells via Inhibiting Oxidative Stress, Autophagy, and Apoptosis

(2016) Ya-Ni Huang et al.   MOLECULAR NEUROBIOLOGY

Neuroprotection and antioxidants

(2016) Maria Lalkovicová et al.   Neural Regeneration Research

Oxidative stress and mitochondrial dysfunction-linked neurodegenerative disorders

(2016) Md. Torequl Islam   NEUROLOGICAL RESEARCH

New Insights into the Role of Oxidative Stress Mechanisms in the Pathophysiology and Treatment of Multiple Sclerosis

(2016) Bożena Adamczyk et al.   Oxidative Medicine and Cellular Longevity

Oxidative Stress and Inflammation: What Polyphenols Can Do for Us?

(2016) Tarique Hussain et al.   Oxidative Medicine and Cellular Longevity

Role of ROS and RNS Sources in Physiological and Pathological Conditions

(2016) Sergio Di Meo et al.   Oxidative Medicine and Cellular Longevity

The Role of Reactive Oxygen Species in the Pathogenesis of Alzheimer’s Disease, Parkinson’s Disease, and Huntington’s Disease: A Mini Review

(2016) Shanmugam Manoharan et al.   Oxidative Medicine and Cellular Longevity

ROS and ROS-Mediated Cellular Signaling

(2016) Jixiang Zhang et al.   Oxidative Medicine and Cellular Longevity

Oxidative stress: A major pathogenesis and potential therapeutic target of antioxidative agents in Parkinson’s disease and Alzheimer’s disease

(2016) Tianfang Jiang et al.   PROGRESS IN NEUROBIOLOGY

Protective effect of carnosic acid against paraquat-induced redox impairment and mitochondrial dysfunction in SH-SY5Y cells: Role for PI3K/Akt/Nrf2 pathway

(2016) Marcos Roberto de Oliveira et al.   TOXICOLOGY IN VITRO

Targeting Oxidative Stress in Central Nervous System Disorders

(2016) Manisha Patel   TRENDS IN PHARMACOLOGICAL SCIENCES

Food Antioxidants: Chemical Insights at the Molecular Level

(2016) Annia Galano et al.   Annual Review of Food Science and Technology

Neuroprotective Effects of A Standardized Flavonoid Extract of Safflower Against Neurotoxin-Induced Cellular and Animal Models of Parkinson’s Disease

(2016) Rutong Ren et al.   Scientific Reports

Effects of NO-Hybridization on the Immunomodulatory Properties of the HIV Protease Inhibitors Lopinavir and Ritonavir

(2015) Paolo Fagone et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

The NO-modified HIV protease inhibitor as a valuable drug for hematological malignancies: Role of p70S6K

(2015) Danijela Maksimovic-Ivanic et al.   LEUKEMIA RESEARCH

Oxidative Stress in Neurodegenerative Diseases

(2015) Ewa Niedzielska et al.   MOLECULAR NEUROBIOLOGY

The importance of antioxidants which play the role in cellular response against oxidative/nitrosative stress: current state

(2015) Ergul Belge Kurutas   Nutrition Journal

Measurement and meaning of markers of reactive species of oxygen, nitrogen and sulfur in healthy human subjects and patients with inflammatory joint disease

(2012) Paul G. Winyard et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Is the generation of neo-antigenic determinants by free radicals central to the development of autoimmune rheumatoid disease?

(2008) Helen R. Griffiths   AUTOIMMUNITY REVIEWS