Cyanobacteria—From the Oceans to the Potential Biotechnological and Biomedical Applications

Iheyamides A–C, Antitrypanosomal Linear Peptides Isolated from a Marine Dapis sp. Cyanobacterium

(2020) Naoaki Kurisawa et al.   JOURNAL OF NATURAL PRODUCTS

Marine Algal Antioxidants as Potential Vectors for Controlling Viral Diseases

(2020) Clementina Sansone et al.   Antioxidants

Cyanobacterial metabolites as promising drug leads against the Mpro and PLpro of SARS-CoV-2: an in silico analysis

(2020) Devashan Naidoo et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Exploitation of Filamentous and Picoplanktonic Cyanobacteria for Cosmetic Applications: Potential to Improve Skin Structure and Preserve Dermal Matrix Components

(2020) Janaína Morone et al.   Marine Drugs

Antioxidant and Cytoprotective Properties of Cyanobacteria: Potential for Biotechnological Applications

(2020) Adriana Guerreiro et al.   Toxins

Sensing the interactions between carbohydrate-binding agents and N-linked glycans of SARS-CoV-2 spike glycoprotein using molecular docking and simulation studies

(2020) Kiran Bharat Lokhande et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Natural Products from Cyanobacteria: Focus on Beneficial Activities

(2019) Justine Demay et al.   Marine Drugs

Skin Carotenoids in Public Health and Nutricosmetics: The Emerging Roles and Applications of the UV Radiation-Absorbing Colourless Carotenoids Phytoene and Phytofluene

(2019) Meléndez-Martínez et al.   Nutrients

Cytotoxic Microcolin Lipopeptides from the Marine Cyanobacterium Moorea producens

(2019) Hao-Bing Yu et al.   JOURNAL OF NATURAL PRODUCTS

Isolation and Total Synthesis of Mabuniamide, a Lipopeptide from an Okeania sp. Marine Cyanobacterium

(2019) Kaori Ozaki et al.   JOURNAL OF NATURAL PRODUCTS

Revealing the potential of cyanobacteria in cosmetics and cosmeceuticals — A new bioactive approach

(2019) Janaína Morone et al.   Algal Research-Biomass Biofuels and Bioproducts

Sangivamycin and its derivatives inhibit Haspin-Histone H3-survivin signaling and induce pancreatic cancer cell death

(2019) Ligia I. Bastea et al.   Scientific Reports

An “olivomycin A” derivative from a sponge-associated Streptomyces sp. strain SP 85

(2019) Mohsen Gozari et al.   3 Biotech

Applications of microalgal and cyanobacterial biomass on a way to safe, cleaner and a sustainable environment

(2019) Garlapati Deviram et al.   JOURNAL OF CLEANER PRODUCTION

Single cyanobacteria@silica porous microcapsules via a sol–gel layer by layer for heavy-metal remediation

(2018) Cyrille Delneuville et al.   JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY

Developments of Cyanobacteria for Nano-Marine Drugs: Relevance of Nanoformulations in Cancer Therapies

(2018) Vivek Bajpai et al.   Marine Drugs

Fast Profiling of Natural Pigments in Different Spirulina (Arthrospira platensis) Dietary Supplements by DI-FT-ICR and Evaluation of their Antioxidant Potential by Pre-Column DPPH-UHPLC Assay

(2018) Eduardo Sommella et al.   MOLECULES

Total Synthesis of the Highly N-Methylated Acetylene-Containing Anticancer Peptide Jahanyne

(2018) Andrew Siow et al.   ORGANIC LETTERS

Total synthesis of janadolide

(2018) Daisuke Ojima et al.   TETRAHEDRON LETTERS

First Record of Microbiomes of Sponges Collected From the Persian Gulf, Using Tag Pyrosequencing

(2018) Akram Najafi et al.   Frontiers in Microbiology

Spirulina platensis effectively ameliorates anthropometric measurements and obesity-related metabolic disorders in obese or overweight healthy individuals: A randomized controlled trial

(2018) Reyhaneh Yousefi et al.   COMPLEMENTARY THERAPIES IN MEDICINE

Isolation of Jahanene and Jahanane, and Total Synthesis of the Jahanyne Family

(2018) Arihiro Iwasaki et al.   JOURNAL OF ORGANIC CHEMISTRY

Nano based drug delivery systems: recent developments and future prospects

(2018) Jayanta Kumar Patra et al.   JOURNAL OF NANOBIOTECHNOLOGY

Anticancer Activity of Natural Compounds from Plant and Marine Environment

(2018) Anna Lichota et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Antioxidant and Oxidative Stress: A Mutual Interplay in Age-Related Diseases

(2018) Bee Ling Tan et al.   Frontiers in Pharmacology

Preparation and nanoformulation of new quinolone scaffold-based anticancer agents: Enhancing solubility for better cellular delivery

(2017) Nehal H. Elghazawy et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Skin whitening agents: medicinal chemistry perspective of tyrosinase inhibitors

(2017) Thanigaimalai Pillaiyar et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Biseokeaniamides A, B, and C, Sterol O-Acyltransferase Inhibitors from an Okeania sp. Marine Cyanobacterium

(2017) Arihiro Iwasaki et al.   JOURNAL OF NATURAL PRODUCTS

Total Synthesis of Kanamienamide and Clarification of Biological Activity

(2017) Daisuke Ojima et al.   JOURNAL OF ORGANIC CHEMISTRY

Structural Diversity, Biological Properties and Applications of Natural Products from Cyanobacteria. A Review

(2017) Sayed Shah et al.   Marine Drugs

Isolation and Total Synthesis of Hoshinolactam, an Antitrypanosomal Lactam from a Marine Cyanobacterium

(2017) Hidetoshi Ogawa et al.   ORGANIC LETTERS

In vitro evaluation of Spirulina platensis extract incorporated skin cream with its wound healing and antioxidant activities

(2017) Seda Gunes et al.   PHARMACEUTICAL BIOLOGY

Marine Biopolymer-Based Nanomaterials as a Novel Platform for Theranostic Applications

(2017) Panchanathan Manivasagan et al.   Polymer Reviews

Uncovering Potential Applications of Cyanobacteria and Algal Metabolites in Biology, Agriculture and Medicine: Current Status and Future Prospects

(2017) Rachana Singh et al.   Frontiers in Microbiology

A phase 2 study of glembatumumab vedotin (GV), an antibody-drug conjugate (ADC) targeting gpNMB, in advanced melanoma

(2016) P.A. Ott et al.   ANNALS OF ONCOLOGY

The antioxidant, immunomodulatory, and anti-inflammatory activities of Spirulina: an overview

(2016) Qinghua Wu et al.   ARCHIVES OF TOXICOLOGY

Discovery, Total Synthesis and Key Structural Elements for the Immunosuppressive Activity of Cocosolide, a Symmetrical Glycosylated Macrolide Dimer from Marine Cyanobacteria

(2016) Sarath P. Gunasekera et al.   CHEMISTRY-A EUROPEAN JOURNAL

The Evolution and Versatility of Microalgal Biotechnology: A Review

(2016) Imen Hamed   COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY

The Antioxidant Effects of Radix Astragali (Astragalus membranaceus and Related Species) in Protecting Tissues from Injury and Disease

(2016) Muhammad Shahzad et al.   CURRENT DRUG TARGETS

Seaweeds: A resource for marine bionanotechnology

(2016) Sri Ramkumar Vijayan et al.   ENZYME AND MICROBIAL TECHNOLOGY

Cyanobacterial metabolites as a source of sunscreens and moisturizers: a comparison with current synthetic compounds

(2016) Peyman Derikvand et al.   EUROPEAN JOURNAL OF PHYCOLOGY

Quantification of Phytochemicals from CommercialSpirulinaProducts and Their Antioxidant Activities

(2016) Naif Abdullah Al-Dhabi et al.   Evidence-based Complementary and Alternative Medicine

Herbal extracts, lichens and biomolecules as natural photo-protection alternatives to synthetic UV filters. A systematic review

(2016) Matteo Radice et al.   FITOTERAPIA

Janadolide, a Cyclic Polyketide–Peptide Hybrid Possessing a tert-Butyl Group from an Okeania sp. Marine Cyanobacterium

(2016) Hidetoshi Ogawa et al.   JOURNAL OF NATURAL PRODUCTS

Total Synthesis of Miuraenamides A and D

(2016) Daisuke Ojima et al.   JOURNAL OF ORGANIC CHEMISTRY

Nitrogen fixing cyanobacteria: their diversity, ecology and utilisation with special reference to rice cultivation

(2016) SA Kulasooriya et al.   JOURNAL OF THE NATIONAL SCIENCE FOUNDATION OF SRI LANKA

Chronic Inflammation: Accelerator of Biological Aging

(2016) Bertrand Fougère et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Marine Origin Polysaccharides in Drug Delivery Systems

(2016) Matias Cardoso et al.   Marine Drugs

Total synthesis and stereochemical determination of yoshinone A

(2016) Seiichi Shinomiya et al.   PHYTOCHEMISTRY

Bioethanol from microalgae and cyanobacteria: A review and technological outlook

(2016) Carlos Eduardo de Farias Silva et al.   PROCESS BIOCHEMISTRY

Potential of Synechocystis PCC 6803 as a novel cyanobacterial chassis for heterologous expression of enzymes in the trans-resveratrol biosynthetic pathway

(2016) Supaluk Tantong et al.   PROTEIN EXPRESSION AND PURIFICATION

Odoamide, a cytotoxic cyclodepsipeptide from the marine cyanobacterium Okeania sp.

(2016) Kosuke Sueyoshi et al.   TETRAHEDRON

Total synthesis and absolute configuration of koshikalide

(2016) Kazuki Kunifuda et al.   TETRAHEDRON LETTERS

Cyanobacteria: A Precious Bio-resource in Agriculture, Ecosystem, and Environmental Sustainability

(2016) Jay Shankar Singh et al.   Frontiers in Microbiology

Antioxidant properties in some selected cyanobacteria isolated from fresh water bodies of Sri Lanka

(2016) Md Fuad Hossain et al.   Food Science & Nutrition

Cyclic depsipeptides as potential cancer therapeutics

(2015) Jirouta Kitagaki et al.   ANTI-CANCER DRUGS

Recent developments in therapeutic applications of Cyanobacteria

(2015) Rathinam Raja et al.   CRITICAL REVIEWS IN MICROBIOLOGY

Isolation and Structure of Kurahyne B and Total Synthesis of the Kurahynes

(2015) Shinichiro Okamoto et al.   JOURNAL OF NATURAL PRODUCTS

Total Synthesis of the Potent Marine-Derived Elastase Inhibitor Lyngbyastatin 7 and in Vitro Biological Evaluation in Model Systems for Pulmonary Diseases

(2015) Danmeng Luo et al.   JOURNAL OF ORGANIC CHEMISTRY

Enantioselective Total Synthesis of (+)-Lyngbyabellin M

(2015) Rodrigo Pirovani et al.   Marine Drugs

The importance of antioxidants which play the role in cellular response against oxidative/nitrosative stress: current state

(2015) Ergul Belge Kurutas   Nutrition Journal

Jahanyne, an Apoptosis-Inducing Lipopeptide from the Marine Cyanobacterium Lyngbya sp.

(2015) Arihiro Iwasaki et al.   ORGANIC LETTERS

Total synthesis and stereochemical reassignment of maedamide

(2015) Ayano Takayanagi et al.   TETRAHEDRON LETTERS

Bloom Dynamics of Cyanobacteria and Their Toxins: Environmental Health Impacts and Mitigation Strategies

(2015) Rajesh P. Rastogi et al.   Frontiers in Microbiology

Characterization of a Hot Water Extract of an Edible Cyanobacterium Nostochopsis sp. for Use as an Ingredient in Cosmetics

(2014) Yukinori Yabuta et al.   FOOD SCIENCE AND TECHNOLOGY RESEARCH

The science of dermocosmetics and its role in dermatology

(2014) B. Dreno et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Exploring Bioactive Properties of Marine Cyanobacteria Isolated from the Portuguese Coast: High Potential as a Source of Anticancer Compounds

(2014) Margarida Costa et al.   Marine Drugs

New drugs with antiprotozoal activity from marine algae: a review

(2014) Fábio A.E. Torres et al.   Revista Brasileira de Farmacognosia-Brazilian Journal of Pharmacognosy

An inhibitor of the adipogenic differentiation of 3T3-L1 cells, yoshinone A, and its analogs, isolated from the marine cyanobacterium Leptolyngbya sp.

(2014) Toshiyasu Inuzuka et al.   TETRAHEDRON LETTERS

Kurahyne, an acetylene-containing lipopeptide from a marine cyanobacterial assemblage of Lyngbya sp.

(2014) Arihiro Iwasaki et al.   RSC Advances

Cyanobacteria: potential candidates for drug discovery

(2013) Rakhi Bajpai Dixit et al.   ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY

Partial characterization, UV-induction and photoprotective function of sunscreen pigment, scytonemin from Rivularia sp. HKAR-4

(2013) Rajesh P. Rastogi et al.   CHEMOSPHERE

Characterization of UV-screening compounds, mycosporine-like amino acids, and scytonemin in the cyanobacteriumLyngbyasp. CU2555

(2013) Rajesh P. Rastogi et al.   FEMS MICROBIOLOGY ECOLOGY

Reactive oxygen species and the free radical theory of aging

(2013) Stefan I. Liochev   FREE RADICAL BIOLOGY AND MEDICINE

Total Synthesis of the Marine Cyclic Depsipeptide Viequeamide A

(2013) Dongyu Wang et al.   JOURNAL OF NATURAL PRODUCTS

Coibacins A and B: Total Synthesis and Stereochemical Revision

(2013) Vânia M. T. Carneiro et al.   JOURNAL OF ORGANIC CHEMISTRY

Antitumor Activity of Hierridin B, a Cyanobacterial Secondary Metabolite Found in both Filamentous and Unicellular Marine Strains

(2013) Pedro N. Leão et al.   PLoS One

Present and future global distributions of the marine Cyanobacteria Prochlorococcus and Synechococcus

(2013) P. Flombaum et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cyanobacteria and Cyanotoxins: From Impacts on Aquatic Ecosystems and Human Health to Anticarcinogenic Effects

(2013) Giliane Zanchett et al.   Toxins

Total synthesis and stereochemical revision of lagunamide A

(2012) Lu Dai et al.   CHEMICAL COMMUNICATIONS

Brentuximab Vedotin

(2012) C. Deng et al.   CLINICAL CANCER RESEARCH

Lyngbyabellins K-N from Two Palmyra Atoll Collections of the Marine Cyanobacterium Moorea bouillonii

(2012) Hyukjae Choi et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Analysis of Anabaena vaginicola and Nostoc calcicola from Northern Iran, as rich sources of major carotenoids

(2012) Mehri Seyed Hashtroudi et al.   FOOD CHEMISTRY

Phenylalanine ammonia lyase (PAL) enzyme activity and antioxidant properties of some cyanobacteria isolates

(2012) Selcen Babaoğlu Aydaş et al.   FOOD CHEMISTRY

Mechanisms of free radical-induced damage to DNA

(2012) Miral Dizdaroglu et al.   FREE RADICAL RESEARCH

Enhancing biological hydrogen production from cyanobacteria by removal of excreted products

(2012) Gennady M. Ananyev et al.   JOURNAL OF BIOTECHNOLOGY

The cyanobacterial UV-absorbing pigment scytonemin displays radical-scavenging activity

(2012) Kei Matsui et al.   JOURNAL OF GENERAL AND APPLIED MICROBIOLOGY

Viequeamide A, a Cytotoxic Member of the Kulolide Superfamily of Cyclic Depsipeptides from a Marine Button Cyanobacterium

(2012) Paul D. Boudreau et al.   JOURNAL OF NATURAL PRODUCTS

Bacteriocins — a viable alternative to antibiotics?

(2012) Paul D. Cotter et al.   NATURE REVIEWS MICROBIOLOGY

Coibacins A–D, Antileishmanial Marine Cyanobacterial Polyketides with Intriguing Biosynthetic Origins

(2012) Marcy J. Balunas et al.   ORGANIC LETTERS

Cyanobacteria produce a high variety of hepatotoxic peptides in lichen symbiosis

(2012) U. Kaasalainen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exploring Marine Cyanobacteria for Lead Compounds of Pharmaceutical Importance

(2012) Bushra Uzair et al.   TheScientificWorldJOURNAL

Anti-inflammatory effects of sacran, a novel polysaccharide from Aphanothece sacrum, on 2,4,6-trinitrochlorobenzene–induced allergic dermatitis in vivo

(2011) Nlandu Roger Ngatu et al.   ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY

Genome Mining Demonstrates the Widespread Occurrence of Gene Clusters Encoding Bacteriocins in Cyanobacteria

(2011) Hao Wang et al.   PLoS One

Delivery of antiinflammatory nutraceuticals by nanoparticles for the prevention and treatment of cancer

(2010) Hareesh B. Nair et al.   BIOCHEMICAL PHARMACOLOGY

Toxicity of cyanobacterial bloom in the eutrophic dam reservoir (Southeast Poland)

(2010) Anna Sierosławska et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Genetic Engineering of Algae for Enhanced Biofuel Production

(2010) Randor Radakovits et al.   EUKARYOTIC CELL

Almiramides A−C: Discovery and Development of a New Class of Leishmaniasis Lead Compounds

(2010) Laura M. Sanchez et al.   JOURNAL OF MEDICINAL CHEMISTRY

Lagunamides A and B: Cytotoxic and Antimalarial Cyclodepsipeptides from the Marine CyanobacteriumLyngbya majuscula

(2010) Ashootosh Tripathi et al.   JOURNAL OF NATURAL PRODUCTS

Total synthesis and stereochemical reassignment of tasiamide B

(2010) Tiantian Sun et al.   JOURNAL OF PEPTIDE SCIENCE

New Peptides Isolated from Lyngbya Species: A Review

(2010) Li Liu et al.   Marine Drugs

Bacteriocin as Weapons in the Marine Animal-Associated Bacteria Warfare: Inventory and Potential Applications as an Aquaculture Probiotic

(2010) Florie Desriac et al.   Marine Drugs

The unique mechanistic transformations involved in the biosynthesis of modular natural products from marine cyanobacteria

(2010) Adam C. Jones et al.   NATURAL PRODUCT REPORTS

Two cytotoxic stereoisomers of malyngamide C, 8-epi-malyngamide C and 8-O-acetyl-8-epi-malyngamide C, from the marine cyanobacterium Lyngbya majuscula

(2010) Harald Gross et al.   PHYTOCHEMISTRY

Microbial excavation of solid carbonates powered by P-type ATPase-mediated transcellular Ca2+ transport

(2010) F. Garcia-Pichel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biotechnological and industrial significance of cyanobacterial secondary metabolites

(2009) Rajesh P. Rastogi et al.   BIOTECHNOLOGY ADVANCES

ARC (NSC 188491) has identical activity to Sangivamycin (NSC 65346) including inhibition of both P-TEFb and PKC

(2009) Luke H Stockwin et al.   BMC CANCER

Cyclodepsipeptides - Potential Drugs and Lead Compounds in the Drug Development Process

(2009) R. Lemmens-Gruber et al.   CURRENT MEDICINAL CHEMISTRY

Energy biotechnology with cyanobacteria

(2009) S Andreas Angermayr et al.   CURRENT OPINION IN BIOTECHNOLOGY

Desmethoxymajusculamide C, a Cyanobacterial Depsipeptide with Potent Cytotoxicity in Both Cyclic and Ring-Opened Forms

(2009) T. Luke Simmons et al.   JOURNAL OF NATURAL PRODUCTS

Dragonamide E, a Modified Linear Lipopeptide fromLyngbya majusculawith Antileishmanial Activity

(2009) Marcy J. Balunas et al.   JOURNAL OF NATURAL PRODUCTS

Isolation and structure of koshikalide, a 14-membered macrolide from the marine cyanobacterium Lyngbya sp.

(2009) Arihiro Iwasaki et al.   TETRAHEDRON LETTERS

Neurotoxic cyanobacterial toxins

(2009) Rómulo Aráoz et al.   TOXICON

Applications of cyanobacteria in biotechnology

(2008) R.M.M. Abed et al.   JOURNAL OF APPLIED MICROBIOLOGY

Cyanovirin-N potently inhibits human immunodeficiency virus type 1 infection in cellular and cervical explant models

(2008) V. Buffa et al.   JOURNAL OF GENERAL VIROLOGY

Dragonamides C and D, Linear Lipopeptides from the Marine Cyanobacterium BrownLyngbya polychroa

(2008) Sarath P. Gunasekera et al.   JOURNAL OF NATURAL PRODUCTS

Apratoxin D, a Potent Cytotoxic Cyclodepsipeptide from Papua New Guinea Collections of the Marine CyanobacteriaLyngbya majusculaandLyngbya sordida

(2008) Marcelino Gutiérrez et al.   JOURNAL OF NATURAL PRODUCTS

Total Structure Determination of Grassypeptolide, a New Marine Cyanobacterial Cytotoxin

(2008) Jason C. Kwan et al.   ORGANIC LETTERS

Novel approaches in herbal cosmetics

(2008) Deep Chanchal et al.   Journal of Cosmetic Dermatology

Symplocamide A, a Potent Cytotoxin and Chymotrypsin Inhibitor from the Marine CyanobacteriumSymplocasp.

(2007) Roger G. Linington et al.   JOURNAL OF NATURAL PRODUCTS