Protein N-myristoylation: functions and mechanisms in control of innate immunity

Genome Composition and Divergence of the Novel Coronavirus (2019-nCoV) Originating in China

(2020) Aiping Wu et al.   Cell Host & Microbe

China’s response to a novel coronavirus stands in stark contrast to the 2002 SARS outbreak response

(2020) John Nkengasong   NATURE MEDICINE

High-resolution snapshots of human N-myristoyltransferase in action illuminate a mechanism promoting N-terminal Lys and Gly myristoylation

(2020) Cyril Dian et al.   Nature Communications

NMT1 and NMT2 are lysine myristoyltransferases regulating the ARF6 GTPase cycle

(2020) Tatsiana Kosciuk et al.   Nature Communications

N-myristoylation: from cell biology to translational medicine

(2020) Meng Yuan et al.   ACTA PHARMACOLOGICA SINICA

Inhibition of SARS-CoV-2 Infections in Engineered Human Tissues Using Clinical-Grade Soluble Human ACE2

(2020) Vanessa Monteil et al.   CELL

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor

(2020) Jun Lan et al.   NATURE

Myristoylation, an Ancient Protein Modification Mirroring Eukaryogenesis and Evolution

(2020) Thierry Meinnel et al.   TRENDS IN BIOCHEMICAL SCIENCES

A neutralizing human antibody binds to the N-terminal domain of the Spike protein of SARS-CoV-2

(2020) Xiangyang Chi et al.   SCIENCE

Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model

(2020) Thomas F. Rogers et al.   SCIENCE

Distinct conformational states of SARS-CoV-2 spike protein

(2020) Yongfei Cai et al.   SCIENCE

SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies

(2020) Christopher O. Barnes et al.   NATURE

Spike mutation D614G alters SARS-CoV-2 fitness

(2020) Jessica A. Plante et al.   NATURE

SARS-CoV-2 and COVID-19: From the Bench to the Bedside

(2020) Stefano Romagnoli et al.   PHYSIOLOGICAL REVIEWS

In situ structural analysis of SARS-CoV-2 spike reveals flexibility mediated by three hinges

(2020) Beata Turoňová et al.   SCIENCE

De novo design of picomolar SARS-CoV-2 miniprotein inhibitors

(2020) Longxing Cao et al.   SCIENCE

HDAC11 regulates type I interferon signaling through defatty-acylation of SHMT2

(2019) Ji Cao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A deep proteome and transcriptome abundance atlas of 29 healthy human tissues

(2019) Dongxue Wang et al.   Molecular Systems Biology

Coronavirus envelope protein: current knowledge

(2019) Dewald Schoeman et al.   Virology Journal

Myristoylation-Dependent Palmitoylation of the Receptor Tyrosine Kinase Adaptor FRS2α

(2019) Barbara Barylko et al.   BIOCHEMISTRY

A glycine-specific N-degron pathway mediates the quality control of protein N-myristoylation

(2019) Richard T. Timms et al.   SCIENCE

TLR8 Is a Sensor of RNase T2 Degradation Products

(2019) Wilhelm Greulich et al.   CELL

Innate Immunity

(2019) Bani Preet Kaur et al.   PEDIATRIC CLINICS OF NORTH AMERICA

Protein Lipidation: Occurrence, Mechanisms, Biological Functions, and Enabling Technologies

(2018) Hong Jiang et al.   CHEMICAL REVIEWS

Myristoylation: An Important Protein Modification in the Immune Response

(2017) Daniel Ikenna Udenwobele et al.   Frontiers in Immunology

Importance of Nucleic Acid Recognition in Inflammation and Autoimmunity

(2016) Franck J. Barrat et al.   Annual Review of Medicine

Inhibition of enterovirus VP4 myristoylation is a potential antiviral strategy for hand, foot and mouth disease

(2016) Yong Wah Tan et al.   ANTIVIRAL RESEARCH

Recognition of Endogenous Nucleic Acids by the Innate Immune System

(2016) Axel Roers et al.   IMMUNITY

Innate immunity in vertebrates: an overview

(2016) Mario Riera Romo et al.   IMMUNOLOGY

Innate Immune Pattern Recognition: A Cell Biological Perspective

(2015) Sky W. Brubaker et al.   Annual Review of Immunology

C-type lectins in immunity: recent developments

(2015) Ivy M Dambuza et al.   CURRENT OPINION IN IMMUNOLOGY

Heme oxygenase-2 deletion impairs macrophage function: implication in wound healing

(2015) Lars Bellner et al.   FASEB JOURNAL

Phosphatase PTPN4 Preferentially Inhibits TRIF-Dependent TLR4 Pathway by Dephosphorylating TRAM

(2015) Wanwan Huai et al.   JOURNAL OF IMMUNOLOGY

Myristoylome Profiling Reveals a Concerted Mechanism of ARF GTPase Deacylation by the Bacterial Protease IpaJ

(2015) Nikolay Burnaevskiy et al.   MOLECULAR CELL

HIV-1 assembly, release and maturation

(2015) Eric O. Freed   NATURE REVIEWS MICROBIOLOGY

Requirement of N-Myristoyltransferase 1 in the Development of Monocytic Lineage

(2014) A. Shrivastav et al.   JOURNAL OF IMMUNOLOGY

Heme Oxygenase-2 Suppress TNF-α and IL6 Expression via TLR4/MyD88-Dependent Signaling Pathway in Mouse Cerebral Vascular Endothelial Cells

(2014) Ren-Jin Chen et al.   MOLECULAR NEUROBIOLOGY

Induction of Siglec-G by RNA Viruses Inhibits the Innate Immune Response by Promoting RIG-I Degradation

(2013) Weilin Chen et al.   CELL

Cytosolic Sensing of Viruses

(2013) Delphine Goubau et al.   IMMUNITY

Plant innate immunity: An updated insight into defense mechanism

(2013) Mehanathan Muthamilarasan et al.   JOURNAL OF BIOSCIENCES

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome

(2013) Yangyang Bian et al.   Journal of Proteomics

Proteolytic elimination of N-myristoyl modifications by the Shigella virulence factor IpaJ

(2013) Nikolay Burnaevskiy et al.   NATURE

Cutting Edge: TLR13 Is a Receptor for Bacterial RNA

(2012) A. Hidmark et al.   JOURNAL OF IMMUNOLOGY

Toward a Comprehensive Characterization of a Human Cancer Cell Phosphoproteome

(2012) Houjiang Zhou et al.   JOURNAL OF PROTEOME RESEARCH

ARF family G proteins and their regulators: roles in membrane transport, development and disease

(2011) Julie G. Donaldson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

SENP2 negatively regulates cellular antiviral response by deSUMOylating IRF3 and conditioning it for ubiquitination and degradation

(2011) Yong Ran et al.   Journal of Molecular Cell Biology

Induction and function of type I and III interferon in response to viral infection

(2011) David E Levy et al.   Current Opinion in Virology

Bacterial Contact-Dependent Delivery Systems

(2010) Christopher S. Hayes et al.   Annual Review of Genetics

Post-translational myristoylation: Fat matters in cellular life and death

(2010) Dale D.O. Martin et al.   BIOCHIMIE

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

Myristoylation of the dual-specificity phosphatase c-JUN N-terminal kinase (JNK) stimulatory phosphatase 1 is necessary for its activation of JNK signaling and apoptosis

(2010) Ulla Schwertassek et al.   FEBS Journal

Myristoylated Naked2 Antagonizes Wnt-β-Catenin Activity by Degrading Dishevelled-1 at the Plasma Membrane

(2010) Tianhui Hu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

Regulation of Adaptive Immunity by the Innate Immune System

(2010) A. Iwasaki et al.   SCIENCE

Quantitative Phosphoproteomics Reveals Widespread Full Phosphorylation Site Occupancy During Mitosis

(2010) J. V. Olsen et al.   Science Signaling

Dual Acylation Accounts for the Localization of α19-Giardin in the Ventral Flagellum Pair ofGiardia lamblia

(2009) Mirela Šarić et al.   EUKARYOTIC CELL

Toward a model for Arf GTPases as regulators of traffic at the Golgi

(2009) Richard A. Kahn   FEBS LETTERS

Recognition of Lipopeptide Patterns by Toll-like Receptor 2-Toll-like Receptor 6 Heterodimer

(2009) Jin Young Kang et al.   IMMUNITY

Structure and Membrane Interaction of Myristoylated ARF1

(2009) Yizhou Liu et al.   STRUCTURE

Expression and activity of N-myristoyltransferase in lung inflammation of cattle and its role in neutrophil apoptosis

(2009) Anuraag Shrivastav et al.   VETERINARY RESEARCH

Innate immunity to virus infection

(2008) Osamu Takeuchi et al.   IMMUNOLOGICAL REVIEWS

A quantitative atlas of mitotic phosphorylation

(2008) N. Dephoure et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA