A glycine-specific N-degron pathway mediates the quality control of protein N-myristoylation

N-degron and C-degron pathways of protein degradation

(2019) Alexander Varshavsky   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Eukaryotic Proteome Is Shaped by E3 Ubiquitin Ligases Targeting C-Terminal Degrons

(2018) Itay Koren et al.   CELL

Mapping Degradation Signals and Pathways in a Eukaryotic N-terminome

(2018) Ilia Kats et al.   MOLECULAR CELL

Fragment-derived inhibitors of human N-myristoyltransferase block capsid assembly and replication of the common cold virus

(2018) Aurélie Mousnier et al.   Nature Chemistry

Recognition of the Diglycine C-End Degron by CRL2KLHDC2 Ubiquitin Ligase

(2018) Domniţa-Valeria Rusnac et al.   MOLECULAR CELL

An N-end rule pathway that recognizes proline and destroys gluconeogenic enzymes

(2017) Shun-Jia Chen et al.   SCIENCE

Degrons in cancer

(2017) Bálint Mészáros et al.   Science Signaling

Degrons in cancer

(2017) Bálint Mészáros et al.   Science Signaling

Metazoan evolution of the armadillo repeat superfamily

(2016) Ismail Sahin Gul et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The ubiquitin ligase CRL2 ZYG11 targets cyclin B1 for degradation in a conserved pathway that facilitates mitotic slippage

(2016) Riju S. Balachandran et al.   JOURNAL OF CELL BIOLOGY

Analysis of protein-coding genetic variation in 60,706 humans

(2016) Monkol Lek et al.   NATURE

First Things First: Vital Protein Marks by N-Terminal Acetyltransferases

(2016) Henriette Aksnes et al.   TRENDS IN BIOCHEMICAL SCIENCES

Rationally designed fluorogenic protease reporter visualizes spatiotemporal dynamics of apoptosis in vivo

(2015) Tsz-Leung To et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

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Improved vectors and genome-wide libraries for CRISPR screening

(2014) Neville E Sanjana et al.   NATURE METHODS

Calpain-generated natural protein fragments as short-lived substrates of the N-end rule pathway

(2014) Konstantin I. Piatkov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Perilous journey: a tour of the ubiquitin–proteasome system

(2014) Gary Kleiger et al.   TRENDS IN CELL BIOLOGY

Global profiling of co- and post-translationally N-myristoylated proteomes in human cells

(2014) Emmanuelle Thinon et al.   Nature Communications

The N-Terminal Methionine of Cellular Proteins as a Degradation Signal

(2013) Heon-Ki Kim et al.   CELL

Control of Protein Quality and Stoichiometries by N-Terminal Acetylation and the N-End Rule Pathway

(2013) Anna Shemorry et al.   MOLECULAR CELL

The DegraBase: A Database of Proteolysis in Healthy and Apoptotic Human Cells

(2012) Emily D. Crawford et al.   MOLECULAR & CELLULAR PROTEOMICS

The Auto-Generated Fragment of the Usp1 Deubiquitylase Is a Physiological Substrate of the N-End Rule Pathway

(2012) Konstantin I. Piatkov et al.   MOLECULAR CELL

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

Seq2Logo: a method for construction and visualization of amino acid binding motifs and sequence profiles including sequence weighting, pseudo counts and two-sided representation of amino acid enrichment and depletion

(2012) Martin Christen Frølund Thomsen et al.   NUCLEIC ACIDS RESEARCH

PROSPER: An Integrated Feature-Based Tool for Predicting Protease Substrate Cleavage Sites

(2012) Jiangning Song et al.   PLoS One

The N-end rule pathway counteracts cell death by destroying proapoptotic protein fragments

(2012) K. I. Piatkov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The N-end rule pathway and regulation by proteolysis

(2011) Alexander Varshavsky   PROTEIN SCIENCE

N-Terminal Acetylation of Cellular Proteins Creates Specific Degradation Signals

(2010) C.-S. Hwang et al.   SCIENCE

An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer

(2009) Teresa A. Soucy et al.   NATURE

Improved visualization of protein consensus sequences by iceLogo

(2009) Niklaas Colaert et al.   NATURE METHODS

Diversity of degradation signals in the ubiquitin–proteasome system

(2008) Tommer Ravid et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Global Protein Stability Profiling in Mammalian Cells

(2008) H.-C. S. Yen et al.   SCIENCE