Curcumin and cardiovascular diseases: Focus on cellular targets and cascades

Curcumin analog A13 alleviates oxidative stress by activating Nrf2/ARE pathway and ameliorates fibrosis in the myocardium of high-fat-diet and streptozotocin-induced diabetic rats

(2020) Lanting Xiang et al.   Diabetology & Metabolic Syndrome

Protective effect of curcumin nanoparticles against cardiotoxicity induced by doxorubicin in rat

(2020) Haitham S. Mohammed et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Curcumin supplementation improves heat-stress-induced cardiac injury of mice: physiological and molecular mechanisms

(2020) Yong Chen et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

The Synthetic Curcumin Analogue GO-Y030 Effectively Suppresses the Development of Pressure Overload-induced Heart Failure in Mice

(2020) Kana Shimizu et al.   Scientific Reports

The impact of curcumin and its modified formulations on Alzheimer's disease

(2019) Tahereh Farkhondeh et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Curcumin attenuates palmitic acid-induced cell apoptosis by inhibiting endoplasmic reticulum stress in H9C2 cardiomyocytes

(2019) G Guan et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Heart Disease and Stroke Statistics—2019 Update: A Report From the American Heart Association

(2019) Emelia J. Benjamin et al.   CIRCULATION

Acetylation of SERCA2a, Another Target for Heart Failure Treatment?

(2019) Xiongwen Chen et al.   CIRCULATION RESEARCH

Tetrahydrocurcumin Ameliorates Diabetic Cardiomyopathy by Attenuating High Glucose-Induced Oxidative Stress and Fibrosis via Activating the SIRT1 Pathway

(2019) Kaifeng Li et al.   Oxidative Medicine and Cellular Longevity

Bisdemethoxycurcumin Protection of Cardiomyocyte Mainly Depends on Nrf2/HO-1 Activation Mediated by the PI3K/AKT Pathway

(2019) Xing Li et al.   CHEMICAL RESEARCH IN TOXICOLOGY

SIRT1 activation attenuates cardiac fibrosis by endothelial-to-mesenchymal transition

(2019) Zhen-Hua Liu et al.   BIOMEDICINE & PHARMACOTHERAPY

Role of TLR4/MyD88/NF-κB signaling pathway in coronary microembolization-induced myocardial injury prevented and treated with nicorandil

(2018) Qiang Su et al.   BIOMEDICINE & PHARMACOTHERAPY

MicroRNA-449a Inhibition Protects H9C2 Cells Against Hypoxia/Reoxygenation-Induced Injury by Targeting the Notch-1 Signaling Pathway

(2018) Jing Cheng et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Featured Article: TGF-β1 dominates extracellular matrix rigidity for inducing differentiation of human cardiac fibroblasts to myofibroblasts

(2018) Nathan Cho et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Curcumin Protects against Atherosclerosis in Apolipoprotein E-Knockout Mice by Inhibiting Toll-like Receptor 4 Expression

(2018) Shanshan Zhang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Curcumin enhances LXRα in an AMP-activated protein kinase-dependent manner in human macrophages

(2018) Javier Sáenz et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Deciphering PPARγ activation in cardiometabolic syndrome: studies by in silico and in vivo experimental assessment

(2018) Rohini Agrawal et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

SIRT3: A New Regulator of Cardiovascular Diseases

(2018) Wei Sun et al.   Oxidative Medicine and Cellular Longevity

Hypolipidemic activity and mechanisms of the total phenylpropanoid glycosides from Ligustrum robustum (Roxb.) Blume by AMPK-SREBP-1c pathway in hamsters fed a high-fat diet

(2018) Runmei Yang et al.   PHYTOTHERAPY RESEARCH

Protection by dimethyl fumarate against diabetic cardiomyopathy in type 1 diabetic mice likely via activation of nuclear factor erythroid-2 related factor 2

(2018) Xinyue Hu et al.   TOXICOLOGY LETTERS

Obesity, Inflammation, Toll-Like Receptor 4 and Fatty Acids

(2018) Marcelo Rogero et al.   Nutrients

c-Jun N-Terminal Kinases (JNKs) in Myocardial and Cerebral Ischemia/Reperfusion Injury

(2018) Maria Shvedova et al.   Frontiers in Pharmacology

Curcumin exerts anti-inflammatory and vasoprotective effects through amelioration of NFAT-dependent endothelin-1 production in mice with acute Chagas cardiomyopathy

(2018) Matías Hernández et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

Curcumin ameliorates atherosclerosis in apolipoprotein E deficient asthmatic mice by regulating the balance of Th2/Treg cells

(2018) Shanshan Gao et al.   PHYTOMEDICINE

Curcumin attenuates doxorubicin-induced cardiotoxicity via suppressing oxidative stress and preventing mitochondrial dysfunction mediated by 14-3-3γ

(2018) Huan He et al.   Food & Function

Curcumin augments the cardioprotective effect of metformin in an experimental model of type I diabetes mellitus; Impact of Nrf2/HO-1 and JAK/STAT pathways

(2018) Eman M. Abdelsamia et al.   BIOMEDICINE & PHARMACOTHERAPY

Arachidonic Acid Metabolites in Cardiovascular and Metabolic Diseases

(2018) Thomas Sonnweber et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A novel curcumin-loaded nanoparticle restricts atherosclerosis development and promotes plaques stability in apolipoprotein E deficient mice

(2018) Ning Meng et al.   JOURNAL OF BIOMATERIALS APPLICATIONS

Protective effects and mechanism of curcumin on myocardial injury induced by coronary microembolization

(2018) Yang Liu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Curcumin protects against diabetic cardiomyopathy by promoting autophagy and alleviating apoptosis

(2018) Qing Yao et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Novel Curcumin C66 That Protects Diabetes-Induced Aortic Damage Was Associated with Suppressing JNK2 and Upregulating Nrf2 Expression and Function

(2018) Cheng Li et al.   Oxidative Medicine and Cellular Longevity

Global, Regional, and National Burden of Cardiovascular Diseases for 10 Causes, 1990 to 2015

(2017) Gregory A. Roth et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Oxidative Stress and Cellular Response to Doxorubicin: A Common Factor in the Complex Milieu of Anthracycline Cardiotoxicity

(2017) Donato Cappetta et al.   Oxidative Medicine and Cellular Longevity

Protective effect of curcumin against myocardium injury in ischemia reperfusion rats

(2017) HuaJin Liu et al.   PHARMACEUTICAL BIOLOGY

DDiT4L promotes autophagy and inhibits pathological cardiac hypertrophy in response to stress

(2017) Bridget Simonson et al.   Science Signaling

Curcumin attenuates myocardial ischemia–reperfusion injury

(2017) Kun Liu et al.   Oncotarget

DDiT4L promotes autophagy and inhibits pathological cardiac hypertrophy in response to stress

(2017) Bridget Simonson et al.   Science Signaling

High Sensitivity of SIRT3 Deficient Hearts to Ischemia-Reperfusion Is Associated with Mitochondrial Abnormalities

(2017) Rebecca M. Parodi-Rullán et al.   Frontiers in Pharmacology

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

Curcumin protects cardiac myocyte against hypoxia-induced apoptosis through upregulating miR-7a/b expression

(2016) Hai-Hua Geng et al.   BIOMEDICINE & PHARMACOTHERAPY

Cardiac Fibrosis

(2016) Joshua G. Travers et al.   CIRCULATION RESEARCH

Chronic Hypobaric Hypoxia Induces Right Ventricular Hypertrophy and Apoptosis in Rats: Therapeutic Potential of Nanocurcumin in Improving Adaptation

(2016) Sarita Nehra et al.   HIGH ALTITUDE MEDICINE & BIOLOGY

SIRT3 in cardiovascular diseases: Emerging roles and therapeutic implications

(2016) Yi Lu et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Endothelin-1 mediates intermittent hypoxia-induced inflammatory vascular remodeling through HIF-1 activation

(2016) Emmanuelle Gras et al.   JOURNAL OF APPLIED PHYSIOLOGY

Notch1 Pathway Protects against Burn-Induced Myocardial Injury by Repressing Reactive Oxygen Species Production through JAK2/STAT3 Signaling

(2016) Weixia Cai et al.   Oxidative Medicine and Cellular Longevity

Targeting the ROS-HIF-1-endothelin axis as a therapeutic approach for the treatment of obstructive sleep apnea-related cardiovascular complications

(2016) Elise Belaidi et al.   PHARMACOLOGY & THERAPEUTICS

Cardioprotective actions of curcumin on the pathogenic NFAT/COX-2/prostaglandin E2 pathway induced during Trypanosoma cruzi infection

(2016) Matías Hernández et al.   PHYTOMEDICINE

Improved bioavailability of targeted Curcumin delivery efficiently regressed cardiac hypertrophy by modulating apoptotic load within cardiac microenvironment

(2016) Aramita Ray et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Curcumin Protects Neonatal Rat Cardiomyocytes against High Glucose-Induced Apoptosis via PI3K/Akt Signalling Pathway

(2016) Wei Yu et al.   Journal of Diabetes Research

Nicotinate-Curcumin Impedes Foam Cell Formation from THP-1 Cells through Restoring Autophagy Flux

(2016) Hong-Feng Gu et al.   PLoS One

Dickkopf-3 protects against cardiac dysfunction and ventricular remodelling following myocardial infarction

(2015) Ming-Wei Bao et al.   BASIC RESEARCH IN CARDIOLOGY

Dickkopf-3 regulates prostate epithelial cell acinar morphogenesis and prostate cancer cell invasion by limiting TGF-β-dependent activation of matrix metalloproteases

(2015) Diana Romero et al.   CARCINOGENESIS

Cardioprotection by Curcumin Post-Treatment in Rats with Established Chronic Kidney Disease

(2015) Sauri Hernández-Reséndiz et al.   CARDIOVASCULAR DRUGS AND THERAPY

Calhex231 Ameliorates Cardiac Hypertrophy by Inhibiting Cellular Autophagy in Vivo and in Vitro

(2015) Lei Liu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Curcumin Enhanced Cholesterol Efflux by Upregulating ABCA1 Expression Through AMPK-SIRT1-LXRα Signaling in THP-1 Macrophage-Derived Foam Cells

(2015) Xiao-long Lin et al.   DNA AND CELL BIOLOGY

Effects of Buprenorphine on Balance of Oxidant/Antioxidant System in the Different Ages of Male Rat Liver

(2015) Saeed Samarghandian et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Curcumin protects hearts from FFA-induced injury by activating Nrf2 and inactivating NF-κB both in vitro and in vivo

(2015) Chunlai Zeng et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Curcumin induces apoptosis in pancreatic cancer cells through the induction of forkhead box O1 and inhibition of the PI3K/Akt pathway

(2015) ZHIMING ZHAO et al.   Molecular Medicine Reports

Curcumin inhibits autophagy and apoptosis in hypoxia/reoxygenation-induced myocytes

(2015) ZHOUQING HUANG et al.   Molecular Medicine Reports

Novel curcumin analogue 14p protects against myocardial ischemia reperfusion injury through Nrf2-activating anti-oxidative activity

(2015) Weixin Li et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Platycodin-D Induced Autophagy in Non-Small Cell Lung Cancer Cells via PI3K/Akt/mTOR and MAPK Signaling Pathways

(2015) Ruolin Zhao et al.   Journal of Cancer

Role of the MAPKs/TGF-β1/TRAF6 Signaling Pathway in Atrial Fibrosis of Patients with Chronic Atrial Fibrillation and Rheumatic Mitral Valve Disease

(2014) Daoliang Zhang et al.   CARDIOLOGY

High glucose induces Smad activation via the transcriptional coregulator p300 and contributes to cardiac fibrosis and hypertrophy

(2014) Antoinette Bugyei-Twum et al.   Cardiovascular Diabetology

Dickkopf-3 attenuates pressure overload-induced cardiac remodelling

(2014) Yan Zhang et al.   CARDIOVASCULAR RESEARCH

Induction of Myocardial PDCD4 in Coronary Microembolization-Related Cardiac Dysfunction: Evidence from a Large-Animal Study

(2014) Qiang Su et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Inhibition of JNK Phosphorylation by a Novel Curcumin Analog Prevents High Glucose-Induced Inflammation and Apoptosis in Cardiomyocytes and the Development of Diabetic Cardiomyopathy

(2014) Y. Pan et al.   DIABETES

Emerging roles of Notch signaling in liver disease

(2014) Fabian Geisler et al.   HEPATOLOGY

Endothelin-1 and its role in the pathogenesis of infectious diseases

(2014) Brandi D. Freeman et al.   LIFE SCIENCES

TRPV1 activation impedes foam cell formation by inducing autophagy in oxLDL-treated vascular smooth muscle cells

(2014) B-H Li et al.   Cell Death & Disease

A Review on Antibacterial, Antiviral, and Antifungal Activity of Curcumin

(2014) Soheil Zorofchian Moghadamtousi et al.   Biomed Research International

Isoproterenol instigates cardiomyocyte apoptosis and heart failure via AMPK inactivation-mediated endoplasmic reticulum stress

(2013) Xiao-Zhen Zhuo et al.   APOPTOSIS

Curcumin modulation of high fat diet-induced atherosclerosis and steatohepatosis in LDL receptor deficient mice

(2013) S.T. Hasan et al.   ATHEROSCLEROSIS

Dietary Curcumin Ameliorates Aging-Related Cerebrovascular Dysfunction through the AMPK/Uncoupling Protein 2 Pathway

(2013) Yunfei Pu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

NFAT Gene Family in Inflammation and Cancer

(2013) M.-G. Pan et al.   CURRENT MOLECULAR MEDICINE

Combination of D942 With Curcumin Protects Cardiomyocytes From Ischemic Damage Through Promoting Autophagy

(2013) Keping Yang et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS

Mitogen-Activated Protein Kinase-Activated Protein Kinases 2 and 3 Regulate SERCA2a Expression and Fiber Type Composition To Modulate Skeletal Muscle and Cardiomyocyte Function

(2013) M. Scharf et al.   MOLECULAR AND CELLULAR BIOLOGY

The complexity of NF-κB signaling in inflammation and cancer

(2013) Bastian Hoesel et al.   Molecular Cancer

Induction of an Inflammatory Loop by Interleukin-1β and Tumor Necrosis Factor-α Involves NF-kB and STAT-1 in Differentiated Human Neuroprogenitor Cells

(2013) Subbiah Pugazhenthi et al.   PLoS One

Palmitate induces interleukin-8 expression in human aortic vascular smooth muscle cells via Toll-like receptor 4/nuclear factor-κB pathway (TLR4/NF-κB通路介导了软脂酸诱导人主动脉血管平滑肌细胞白细胞介素-8的基因表达)

(2013) Jinxing Quan et al.   Journal of Diabetes

Hypoxic preconditioning protects microvascular endothelial cells against hypoxia/reoxygenation injury by attenuating endoplasmic reticulum stress

(2012) Xu-Dong Wu et al.   APOPTOSIS

Curcumin induces autophagy to protect vascular endothelial cell survival from oxidative stress damage

(2012) Jing Han et al.   Autophagy

The effects of curcumin post-treatment against myocardial ischemia and reperfusion by activation of the JAK2/STAT3 signaling pathway

(2012) Weixun Duan et al.   BASIC RESEARCH IN CARDIOLOGY

Inhibition of histone acetylation by curcumin reduces alcohol-induced expression of heart development-related transcription factors in cardiac progenitor cells

(2012) Linyi Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Differential suppression of intracellular reactive oxygen species-mediated signaling pathway in vascular endothelial cells by several subclasses of flavonoids

(2012) Long Yi et al.   BIOCHIMIE

Curcumin promotes cardiac repair and ameliorates cardiac dysfunction following myocardial infarction

(2012) Ning-Ping Wang et al.   BRITISH JOURNAL OF PHARMACOLOGY

Curcumin inhibits gene expression of receptor for advanced glycation end-products (RAGE) in hepatic stellate cells in vitro by elevating PPARγ activity and attenuating oxidative stress

(2012) Jianguo Lin et al.   BRITISH JOURNAL OF PHARMACOLOGY

Emerging role of epigenetics and miRNA in diabetic cardiomyopathy

(2012) Mohamed Asrih et al.   CARDIOVASCULAR PATHOLOGY

Autophagy as a therapeutic target for ischaemia /reperfusion injury? Concepts, controversies, and challenges

(2012) K. Przyklenk et al.   CARDIOVASCULAR RESEARCH

Association of Sp1 Tandem Repeat Polymorphism ofALOX5with Coronary Artery Disease in Indian Subjects

(2012) Seema P. Todur et al.   CTS-Clinical and Translational Science

Curcumin Protects Against Regional Myocardial Ischemia/Reperfusion Injury Through Activation of RISK/GSK-3β and Inhibition of p38 MAPK and JNK

(2012) Cheol-Won Jeong et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS

Curcumin reduces the cardiac ischemia–reperfusion injury: involvement of the toll-like receptor 2 in cardiomyocytes

(2012) Yong Sook Kim et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

β-Adrenergic receptor stimulation induces endoplasmic reticulum stress in adult cardiac myocytes: role in apoptosis

(2012) Suman Dalal et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Dietary curcumin inhibits atherosclerosis by affecting the expression of genes involved in leukocyte adhesion and transendothelial migration

(2012) Dilek Coban et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Curcumin attenuates rat thoracic aortic aneurysm formation by inhibition of the c-Jun N-terminal kinase pathway and apoptosis

(2012) Jun Fan et al.   NUTRITION

Macrophage-Stimulated Cardiac Fibroblast Production of IL-6 Is Essential for TGF β/Smad Activation and Cardiac Fibrosis Induced by Angiotensin II

(2012) Feifei Ma et al.   PLoS One

Heparin-Binding EGF-Like Growth Factor Induces Heart Interstitial Fibrosis via an Akt/mTor/p70s6k Pathway

(2012) Hong Lian et al.   PLoS One

Curcumin Alleviates Diabetic Cardiomyopathy in Experimental Diabetic Rats

(2012) Wei Yu et al.   PLoS One

PI3K-PKB/Akt Pathway

(2012) B. A. Hemmings et al.   Cold Spring Harbor Perspectives in Biology

MAP Kinase Pathways

(2012) D. K. Morrison   Cold Spring Harbor Perspectives in Biology

Endothelin-1 contributes to increased NFATc3 activation by chronic hypoxia in pulmonary arteries

(2011) Sergio de Frutos et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

PPARs are a unique set of fatty acid regulated transcription factors controlling both lipid metabolism and inflammation

(2011) Tamas Varga et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Attenuation of CHOP-mediated Myocardial Apoptosis in Pressure-overloaded Dominant Negative p38α Mitogen-activated Protein Kinase Mice

(2011) Flori R. Sari et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Induction of cardiac fibroblast lysyl oxidase by TGF-β1 requires PI3K/Akt, Smad3, and MAPK signaling

(2011) Tetyana G. Voloshenyuk et al.   CYTOKINE

Diabetic Downregulation of Nrf2 Activity via ERK Contributes to Oxidative Stress-Induced Insulin Resistance in Cardiac Cells In Vitro and In Vivo

(2011) Y. Tan et al.   DIABETES

Inhibition of cardiac oxidative and endoplasmic reticulum stress-mediated apoptosis by curcumin treatment contributes to protection against acute myocarditis

(2011) Sayaka Mito et al.   FREE RADICAL RESEARCH

LOX-1 abrogation reduces cardiac hypertrophy and collagen accumulation following chronic ischemia in the mouse

(2011) J Lu et al.   GENE THERAPY

MMP-9 Inhibition by ACE Inhibitor Reduces Oxidized LDL-Mediated Foam-Cell Formation

(2011) Chiari Kojima et al.   Journal of Atherosclerosis and Thrombosis

Curcumin: a potential therapeutic polyphenol, prevents noradrenaline-induced hypertrophy in rat cardiac myocytes

(2011) Suchit Ahuja et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Sirt3 Mediates Reduction of Oxidative Damage and Prevention of Age-Related Hearing Loss under Caloric Restriction

(2010) Shinichi Someya et al.   CELL

Proteomic and biochemical analysis of 14-3-3-binding proteins during C2-ceramide-induced apoptosis

(2010) Mercedes Pozuelo-Rubio   FEBS Journal

Identification of Two Nuclear Factor of Activated T-cells (NFAT)-response Elements in the 5′-Upstream Regulatory Region of the ET-1 Promoter

(2010) Kevin A. Strait et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Curcumin Reduces Angiotensin II–mediated Cardiomyocyte Growth via LOX-1 Inhibition

(2010) Bum-Yong Kang et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

TGFβ signaling in the brain increases with aging and signals to astrocytes and innate immune cells in the weeks after stroke

(2010) Kristian P Doyle et al.   Journal of Neuroinflammation

A model of ischemia and reperfusion increases JNK activity, inhibits the association of BAD and 14-3-3, and induces apoptosis of rabbit spinal neurocytes

(2010) Jin Fan et al.   NEUROSCIENCE LETTERS

Hypocholesterolemic effects of curcumin via up-regulation of cholesterol 7a-hydroxylase in rats fed a high fat diet

(2010) Minji Kim et al.   Nutrition Research and Practice

Activation of NF-κB by Palmitate in Endothelial Cells

(2009) Ezekiel Maloney et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Simvastatin Inhibits Angiotensin II-Induced Abdominal Aortic Aneurysm Formation in Apolipoprotein E-Knockout Mice

(2009) Yali Zhang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Using LC3 to monitor autophagy flux in the retinal pigment epithelium

(2009) Ai Ling Wang et al.   Autophagy

FGF-inducible 14-kDa protein (Fn14) is regulated via the RhoA/ROCK kinase pathway in cardiomyocytes and mediates nuclear factor-kappaB activation by TWEAK

(2009) Emmanuel Chorianopoulos et al.   BASIC RESEARCH IN CARDIOLOGY

Native and reconstituted HDL protect cardiomyocytes from doxorubicin-induced apoptosis

(2009) Miguel A. Frias et al.   CARDIOVASCULAR RESEARCH

NF-κB-induced oxidative stress contributes to mitochondrial and cardiac dysfunction in type II diabetes

(2009) Nithya Mariappan et al.   CARDIOVASCULAR RESEARCH

Coronary Microembolization

(2009) Gerd Heusch et al.   CIRCULATION

Inactivation of GSK-3  by Metallothionein Prevents Diabetes-Related Changes in Cardiac Energy Metabolism, Inflammation, Nitrosative Damage, and Remodeling

(2009) Y. Wang et al.   DIABETES

The protective role of curcumin in cardiovascular diseases

(2009) Wanwarang Wongcharoen et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

mTOR signaling at a glance

(2009) M. Laplante et al.   JOURNAL OF CELL SCIENCE

Choosing hamsters but not rats as a model for studying plasma cholesterol-lowering activity of functional foods

(2009) Zesheng Zhang et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Discovery of Atg5/Atg7-independent alternative macroautophagy

(2009) Yuya Nishida et al.   NATURE

Endoplasmic Reticulum Stress in Disease Pathogenesis

(2008) Jonathan H. Lin et al.   Annual Review of Pathology-Mechanisms of Disease

Effects and underlying mechanisms of curcumin on the proliferation of vascular smooth muscle cells induced by Chol:MβCD

(2008) Li Qin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Oxidative stress and left ventricular remodelling after myocardial infarction

(2008) M. Hori et al.   CARDIOVASCULAR RESEARCH

High-Mobility Group Box-1 in Ischemia-Reperfusion Injury of the Heart

(2008) Martin Andrassy et al.   CIRCULATION

Curcumin protects cardiac cells against ischemia-reperfusion injury: effects on oxidative stress, NF-κB, and JNK pathways

(2008) Claudia Fiorillo et al.   FREE RADICAL BIOLOGY AND MEDICINE

High glucose attenuates VEGF expression in rat multipotent adult progenitor cells in association with inhibition of JAK2/STAT3 signalling

(2008) Zehao Liu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy

(2008) I. H. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA