Curcumin exerts anti-inflammatory and vasoprotective effects through amelioration of NFAT-dependent endothelin-1 production in mice with acute Chagas cardiomyopathy

Curcumin Enhances the Anti-Trypanosoma cruzi Activity of Benznidazole-Based Chemotherapy in Acute Experimental Chagas Disease

(2016) Rômulo Dias Novaes et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Cardioprotective actions of curcumin on the pathogenic NFAT/COX-2/prostaglandin E2 pathway induced during Trypanosoma cruzi infection

(2016) Matías Hernández et al.   PHYTOMEDICINE

Mechanisms of vascular dysfunction in acute phase of Trypanosoma cruzi infection in mice

(2016) Josiane F. Silva et al.   VASCULAR PHARMACOLOGY

Antitrypanosomal Treatment with Benznidazole Is Superior to Posaconazole Regimens in Mouse Models of Chagas Disease

(2015) Shilpi Khare et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Cyclooxygenase-2 and Prostaglandin E2 Signaling through Prostaglandin Receptor EP-2 Favor the Development of Myocarditis during Acute Trypanosoma cruzi Infection

(2015) Néstor A. Guerrero et al.   PLoS Neglected Tropical Diseases

Endothelin-1 and its role in the pathogenesis of infectious diseases

(2014) Brandi D. Freeman et al.   LIFE SCIENCES

Cardiopathogenic mediators generated by GATA4 signaling upon co-activation with endothelin-1 and Trypanosoma cruzi infection

(2014) Cristina S. Rigazio et al.   MICROBIAL PATHOGENESIS

Trypanosoma cruzi Infection and Endothelin-1 Cooperatively Activate Pathogenic Inflammatory Pathways in Cardiomyocytes

(2013) Ricardo S. Corral et al.   PLoS Neglected Tropical Diseases

Therapeutic Roles of Curcumin: Lessons Learned from Clinical Trials

(2012) Subash C. Gupta et al.   AAPS Journal

Curcumin Suppresses T Cell Activation by Blocking Ca 2+ Mobilization and Nuclear Factor of Activated T Cells (NFAT) Activation

(2012) Christian Kliem et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Curcumin treatment provides protection against Trypanosoma cruzi infection

(2012) Fnu Nagajyothi et al.   PARASITOLOGY RESEARCH

Chagasic cardiomyopathy, from acute to chronic: is this mediated by host susceptibility factors?

(2012) Andrés F. Henao-Martínez et al.   TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE

Endothelin-1 contributes to increased NFATc3 activation by chronic hypoxia in pulmonary arteries

(2011) Sergio de Frutos et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Identification of Two Nuclear Factor of Activated T-cells (NFAT)-response Elements in the 5′-Upstream Regulatory Region of the ET-1 Promoter

(2010) Kevin A. Strait et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chronic Trypanosoma cruzi-elicited cardiomyopathy: from the discovery to the proposal of rational therapeutic interventions targeting cell adhesion molecules and chemokine receptors - how to make a dream come true

(2009) Joseli Lannes-Vieira et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

Effect of NCB-02, Atorvastatin and Placebo on Endothelial Function, Oxidative Stress and Inflammatory Markers in Patients with Type 2 Diabetes Mellitus

(2008) P Usharani et al.   Drugs in research & development