Novel Compounds Targeting Neuropilin Receptor 1 with Potential To Interfere with SARS-CoV-2 Virus Entry
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Novel Compounds Targeting Neuropilin Receptor 1 with Potential To Interfere with SARS-CoV-2 Virus Entry
Authors
Keywords
-
Journal
ACS Chemical Neuroscience
Volume 12, Issue 8, Pages 1299-1312
Publisher
American Chemical Society (ACS)
Online
2021-03-31
DOI
10.1021/acschemneuro.0c00619
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Discovery of a novel fluorescent chemical probe suitable for evaluation of neuropilin‐1 binding of small molecules
- (2020) Daniel Conole et al. DRUG DEVELOPMENT RESEARCH
- An interactive web-based dashboard to track COVID-19 in real time
- (2020) Ensheng Dong et al. LANCET INFECTIOUS DISEASES
- Structural basis for the recognition of the SARS-CoV-2 by full-length human ACE2
- (2020) Renhong Yan et al. SCIENCE
- Structural and Functional Basis of SARS-CoV-2 Entry by Using Human ACE2
- (2020) Qihui Wang et al. CELL
- SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
- (2020) Markus Hoffmann et al. CELL
- Switch from oral anticoagulants to parenteral heparin in SARS-CoV-2 hospitalized patients
- (2020) Sophie Testa et al. Internal and Emergency Medicine
- A Multibasic Cleavage Site in the Spike Protein of SARS-CoV-2 Is Essential for Infection of Human Lung Cells
- (2020) Markus Hoffmann et al. MOLECULAR CELL
- Review on natural products databases: where to find data in 2020
- (2020) Maria Sorokina et al. Journal of Cheminformatics
- Transmembrane Peptides as Inhibitors of Protein-Protein Interactions: An Efficient Strategy to Target Cancer Cells?
- (2020) Camille Albrecht et al. Frontiers in Oncology
- Neutralizing Antibody and Soluble ACE2 Inhibition of a Replication-Competent VSV-SARS-CoV-2 and a Clinical Isolate of SARS-CoV-2
- (2020) James Brett Case et al. Cell Host & Microbe
- Neuropilin-1: a checkpoint target with unique implications for cancer immunology and immunotherapy
- (2020) Christopher A Chuckran et al. Journal for ImmunoTherapy of Cancer
- Preclinical Efficacy and Safety of an Anti-Human VEGFA and Anti-Human NRP1 Dual-Targeting Bispecific Antibody (IDB0076)
- (2020) Jong-Hee Ko et al. Biomolecules
- SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2
- (2020) Thomas Mandel Clausen et al. CELL
- Neuropilin‑1 as a new potential SARS‑CoV‑2 infection mediator implicated in the neurologic features and central nervous system involvement of COVID‑19
- (2020) Julie Davies et al. Molecular Medicine Reports
- KLIFS: an overhaul after the first 5 years of supporting kinase research
- (2020) Georgi K Kanev et al. NUCLEIC ACIDS RESEARCH
- SARS-CoV-2 Spike protein co-opts VEGF-A/Neuropilin-1 receptor signaling to induce analgesia
- (2020) Aubin Moutal et al. PAIN
- Neuropilin-1 is a host factor for SARS-CoV-2 infection
- (2020) James L. Daly et al. SCIENCE
- Neuropilin-1 facilitates SARS-CoV-2 cell entry and infectivity
- (2020) Ludovico Cantuti-Castelvetri et al. SCIENCE
- Urea-Peptide Hybrids as VEGF-A165/NRP-1 Complex Inhibitors with Improved Receptor Affinity and Biological Properties
- (2020) Anna K. Puszko et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Heparin Inhibits Cellular Invasion by SARS-CoV-2: Structural Dependence of the Interaction of the Spike S1 Receptor-Binding Domain with Heparin
- (2020) Courtney J. Mycroft-West et al. THROMBOSIS AND HAEMOSTASIS
- Triazolopeptides Inhibiting the Interaction between Neuropilin-1 and Vascular Endothelial Growth Factor-165
- (2019) Bartlomiej Fedorczyk et al. MOLECULES
- Heparan Sulfate Proteoglycans and Viral Attachment: True Receptors or Adaptation Bias?
- (2019) Cagno et al. Viruses-Basel
- The Blood–Brain Barrier (BBB) Score
- (2019) Mayuri Gupta et al. JOURNAL OF MEDICINAL CHEMISTRY
- Dual-targeting of EGFR and Neuropilin-1 attenuates resistance to EGFR-targeted antibody therapy in KRAS-mutant non-small cell lung cancer
- (2019) Ye-Jin Kim et al. CANCER LETTERS
- Dual Action of Sulfated Hyaluronan on Angiogenic Processes in Relation to Vascular Endothelial Growth Factor-A
- (2019) Linda Koehler et al. Scientific Reports
- Vascular endothelial growth factor expression and their action in the synovial membranes of patients with painful knee osteoarthritis
- (2018) Shotaro Takano et al. BMC MUSCULOSKELETAL DISORDERS
- NRPa-308, a new neuropilin-1 antagonist, exerts in vitro anti-angiogenic and anti-proliferative effects and in vivo anti-cancer effects in a mouse xenograft model
- (2018) Wang-Qing Liu et al. CANCER LETTERS
- Architecture and hydration of the arginine-binding site of neuropilin-1
- (2018) Filipa Mota et al. FEBS Journal
- Molecular Pharmacology of VEGF-A Isoforms: Binding and Signalling at VEGFR2
- (2018) Chloe Peach et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Small Molecule Neuropilin-1 Antagonists Combine Antiangiogenic and Antitumor Activity with Immune Modulation through Reduction of Transforming Growth Factor Beta (TGFβ) Production in Regulatory T-Cells
- (2018) Jonathan Powell et al. JOURNAL OF MEDICINAL CHEMISTRY
- Adipose-derived stem cells decrease pain in a rat model of oxaliplatin-induced neuropathy: Role of VEGF-A modulation
- (2018) Lorenzo Di Cesare Mannelli et al. NEUROPHARMACOLOGY
- Branched pentapeptides as potent inhibitors of the vascular endothelial growth factor 165 binding to Neuropilin-1: Design, synthesis and biological activity
- (2018) Dagmara Tymecka et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Two Decades under the Influence of the Rule of Five and the Changing Properties of Approved Oral Drugs
- (2018) Michael D. Shultz JOURNAL OF MEDICINAL CHEMISTRY
- Painful Understanding of VEGF
- (2018) María Llorián-Salvador et al. Frontiers in Pharmacology
- Conformational latitude - activity relationship of KPPR tetrapeptide analogues toward their ability to inhibit binding of vascular endothelial growth factor 165 to neuropilin-1
- (2017) Bartlomiej Fedorczyk et al. JOURNAL OF PEPTIDE SCIENCE
- Structure-activity relationship study of tetrapeptide inhibitors of the Vascular Endothelial Growth Factor A binding to Neuropilin-1
- (2017) Dagmara Tymecka et al. PEPTIDES
- Role of VEGF-A in chronic pain
- (2017) Richard P. Hulse Oncotarget
- Multifaceted Role of Neuropilins in the Immune System: Potential Targets for Immunotherapy
- (2017) Sohini Roy et al. Frontiers in Immunology
- Carbohydrate-based peptidomimetics targeting neuropilin-1: Synthesis, molecular docking study and in vitro biological activities
- (2016) Mylène Richard et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Design, synthesis and in vitro biological evaluation of a small cyclic peptide as inhibitor of vascular endothelial growth factor binding to neuropilin-1
- (2016) Karolina Grabowska et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- VEGF Requires the Receptor NRP-1 To Inhibit Lipopolysaccharide-Dependent Dendritic Cell Maturation
- (2016) Nougboli A. E. Oussa et al. JOURNAL OF IMMUNOLOGY
- The control of alternative splicing by SRSF1 in myelinated afferents contributes to the development of neuropathic pain
- (2016) Richard P. Hulse et al. NEUROBIOLOGY OF DISEASE
- Crystal Structure of the Neuropilin-1 MAM Domain: Completing the Neuropilin-1 Ectodomain Picture
- (2016) Tamas Yelland et al. STRUCTURE
- Inhibition of PlexA1-mediated brain tumor growth and tumor-associated angiogenesis using a transmembrane domain targeting peptide
- (2016) Laurent Jacob et al. Oncotarget
- Inhibition of primary breast tumor growth and metastasis using a neuropilin-1 transmembrane domain interfering peptide
- (2016) Alexia Arpel et al. Oncotarget
- Neuropilin Functions as an Essential Cell Surface Receptor
- (2015) Hou-Fu Guo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- ZINC 15 – Ligand Discovery for Everyone
- (2015) Teague Sterling et al. Journal of Chemical Information and Modeling
- Immunoglobulin Fc-fused, neuropilin-1-specific peptide shows efficient tumor tissue penetration and inhibits tumor growth via anti-angiogenesis
- (2015) Ye-Jin Kim et al. JOURNAL OF CONTROLLED RELEASE
- Neuropilin 1 is an entry factor that promotes EBV infection of nasopharyngeal epithelial cells
- (2015) Hong-Bo Wang et al. Nature Communications
- Discovery of novel inhibitors of vascular endothelial growth factor-A–Neuropilin-1 interaction by structure-based virtual screening
- (2014) Anna Starzec et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Synthesis and structure–activity relationship of non-peptidic antagonists of neuropilin-1 receptor
- (2014) Wang-Qing Liu et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Structure-based discovery of a small non-peptidic Neuropilins antagonist exerting in vitro and in vivo anti-tumor activity on breast cancer model
- (2014) Lucia Borriello et al. CANCER LETTERS
- N-Terminal Modification of VEGF-A C Terminus-Derived Peptides Delineates Structural Features Involved in Neuropilin-1 Binding and Functional Activity
- (2014) Haiyan Jia et al. CHEMBIOCHEM
- A phase I study of the human monoclonal anti-NRP1 antibody MNRP1685A in patients with advanced solid tumors
- (2014) Colin D. Weekes et al. INVESTIGATIONAL NEW DRUGS
- Neuropilin Regulation of Angiogenesis, Arteriogenesis, and Vascular Permeability
- (2014) Alice Plein et al. MICROCIRCULATION
- Regulation of alternative VEGF-A mRNA splicing is a therapeutic target for analgesia
- (2014) R.P. Hulse et al. NEUROBIOLOGY OF DISEASE
- Characterisation of the interaction of neuropilin-1 with heparin and a heparan sulfate mimetic library of heparin-derived sugars
- (2014) Katarzyna A. Uniewicz et al. PeerJ
- Design of a Cyclotide Antagonist of Neuropilin-1 and -2 That Potently Inhibits Endothelial Cell Migration
- (2013) Jennifer A. Getz et al. ACS Chemical Biology
- Protein and ligand preparation: parameters, protocols, and influence on virtual screening enrichments
- (2013) G. Madhavi Sastry et al. JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN
- Tuftsin signals through its receptor neuropilin-1 via the transforming growth factor beta pathway
- (2013) Jillian C. Nissen et al. JOURNAL OF NEUROCHEMISTRY
- Vascular Endothelial Cells Mediate Mechanical Stimulation-Induced Enhancement of Endothelin Hyperalgesia via Activation of P2X2/3 Receptors on Nociceptors
- (2013) E. K. Joseph et al. JOURNAL OF NEUROSCIENCE
- SRPK1 inhibitionin vivo: modulation of VEGF splicing and potential treatment for multiple diseases: Figure 1
- (2012) Sebastian Oltean et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Systemic anti-vascular endothelial growth factor therapies induce a painful sensory neuropathy
- (2012) An Verheyen et al. BRAIN
- Targeting VEGF signalling via the neuropilin co-receptor
- (2012) Snezana Djordjevic et al. DRUG DISCOVERY TODAY
- Structural Basis for Selective Vascular Endothelial Growth Factor-A (VEGF-A) Binding to Neuropilin-1
- (2012) Matthew W. Parker et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Neuropilins lock secreted semaphorins onto plexins in a ternary signaling complex
- (2012) Bert J C Janssen et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Sugar-based peptidomimetics as potential inhibitors of the vascular endothelium growth factor binding to neuropilin-1
- (2010) Alexandre Novoa et al. BIOORGANIC & MEDICINAL CHEMISTRY
- In SilicoDocking and Electrophysiological Characterization of Lacosamide Binding Sites on Collapsin Response Mediator Protein-2 Identifies a Pocket Important in Modulating Sodium Channel Slow Inactivation
- (2010) Yuying Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Small Molecule Inhibitors of the Neuropilin-1 Vascular Endothelial Growth Factor A (VEGF-A) Interaction
- (2010) Ashley Jarvis et al. JOURNAL OF MEDICINAL CHEMISTRY
- Peptide-based interference of the transmembrane domain of neuropilin-1 inhibits glioma growth in vivo
- (2010) C Nasarre et al. ONCOGENE
- HTLV-1 uses HSPG and neuropilin-1 for entry by molecular mimicry of VEGF165
- (2009) S. Lambert et al. BLOOD
- C-end rule peptides mediate neuropilin-1-dependent cell, vascular, and tissue penetration
- (2009) T. Teesalu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Neuropilins: structure, function and role in disease
- (2008) Caroline Pellet-Many et al. BIOCHEMICAL JOURNAL
- Neuropilin-1 Expression on Regulatory T Cells Enhances Their Interactions with Dendritic Cells during Antigen Recognition
- (2008) Milka Sarris et al. IMMUNITY
- Transmembrane Domain Interactions Control Biological Functions of Neuropilin-1
- (2007) Lise Roth et al. MOLECULAR BIOLOGY OF THE CELL
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now