Conformational latitude - activity relationship of KPPR tetrapeptide analogues toward their ability to inhibit binding of vascular endothelial growth factor 165 to neuropilin-1

Design, synthesis and in vitro biological evaluation of a small cyclic peptide as inhibitor of vascular endothelial growth factor binding to neuropilin-1

(2016) Karolina Grabowska et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

CHARMM-GUI Input Generator for NAMD, GROMACS, AMBER, OpenMM, and CHARMM/OpenMM Simulations Using the CHARMM36 Additive Force Field

(2015) Jumin Lee et al.   Journal of Chemical Theory and Computation

Discovery of novel inhibitors of vascular endothelial growth factor-A–Neuropilin-1 interaction by structure-based virtual screening

(2014) Anna Starzec et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis and structure–activity relationship of non-peptidic antagonists of neuropilin-1 receptor

(2014) Wang-Qing Liu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Structure-based discovery of a small non-peptidic Neuropilins antagonist exerting in vitro and in vivo anti-tumor activity on breast cancer model

(2014) Lucia Borriello et al.   CANCER LETTERS

N-Terminal Modification of VEGF-A C Terminus-Derived Peptides Delineates Structural Features Involved in Neuropilin-1 Binding and Functional Activity

(2014) Haiyan Jia et al.   CHEMBIOCHEM

Design of a Cyclotide Antagonist of Neuropilin-1 and -2 That Potently Inhibits Endothelial Cell Migration

(2013) Jennifer A. Getz et al.   ACS Chemical Biology

CHARMM36 all-atom additive protein force field: Validation based on comparison to NMR data

(2013) Jing Huang et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Sequence dependence of C-end rule peptides in binding and activation of neuropilin-1 receptor

(2013) David Zanuy et al.   JOURNAL OF STRUCTURAL BIOLOGY

Structural Basis for Selective Vascular Endothelial Growth Factor-A (VEGF-A) Binding to Neuropilin-1

(2012) Matthew W. Parker et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Signal transduction by vascular endothelial growth factor receptors

(2011) Sina Koch et al.   BIOCHEMICAL JOURNAL

Binding of a C-End Rule Peptide to the Neuropilin-1 Receptor: A Molecular Modeling Approach

(2011) Nurit Haspel et al.   BIOCHEMISTRY

MDAnalysis: A toolkit for the analysis of molecular dynamics simulations

(2011) Naveen Michaud-Agrawal et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Neuropilin-1 expression in cancer and development

(2011) Adrian M Jubb et al.   JOURNAL OF PATHOLOGY

Quantitative ratiometric discrimination between noncancerous and cancerous prostate cells based on neuropilin-1 overexpression

(2011) A. Pallaoro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sugar-based peptidomimetics as potential inhibitors of the vascular endothelium growth factor binding to neuropilin-1

(2010) Alexandre Novoa et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Small Molecule Inhibitors of the Neuropilin-1 Vascular Endothelial Growth Factor A (VEGF-A) Interaction

(2010) Ashley Jarvis et al.   JOURNAL OF MEDICINAL CHEMISTRY

C-end rule peptides mediate neuropilin-1-dependent cell, vascular, and tissue penetration

(2009) T. Teesalu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA